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Items: 30

1.

Rhomboid-Like-2 Intramembrane Protease Mediates Metalloprotease-Independent Regulation of Cadherins.

Battistini C, Rehman M, Avolio M, Arduin A, Valdembri D, Serini G, Tamagnone L.

Int J Mol Sci. 2019 Nov 27;20(23). pii: E5958. doi: 10.3390/ijms20235958.

2.

A rationally designed NRP1-independent superagonist SEMA3A mutant is an effective anticancer agent.

Gioelli N, Maione F, Camillo C, Ghitti M, Valdembri D, Morello N, Darche M, Zentilin L, Cagnoni G, Qiu Y, Giacca M, Giustetto M, Paques M, Cascone I, Musco G, Tamagnone L, Giraudo E, Serini G.

Sci Transl Med. 2018 May 23;10(442). pii: eaah4807. doi: 10.1126/scitranslmed.aah4807. Erratum in: Sci Transl Med. 2018 Jul 25;10(451):.

3.

Sema3F (Semaphorin 3F) Selectively Drives an Extraembryonic Proangiogenic Program.

Regano D, Visintin A, Clapero F, Bussolino F, Valdembri D, Maione F, Serini G, Giraudo E.

Arterioscler Thromb Vasc Biol. 2017 Sep;37(9):1710-1721. doi: 10.1161/ATVBAHA.117.308226. Epub 2017 Jul 20.

4.

TRPM8 inhibits endothelial cell migration via a non-channel function by trapping the small GTPase Rap1.

Genova T, Grolez GP, Camillo C, Bernardini M, Bokhobza A, Richard E, Scianna M, Lemonnier L, Valdembri D, Munaron L, Philips MR, Mattot V, Serini G, Prevarskaya N, Gkika D, Pla AF.

J Cell Biol. 2017 Jul 3;216(7):2107-2130. doi: 10.1083/jcb.201506024. Epub 2017 May 26.

5.

PPFIA1 drives active α5β1 integrin recycling and controls fibronectin fibrillogenesis and vascular morphogenesis.

Mana G, Clapero F, Panieri E, Panero V, Böttcher RT, Tseng HY, Saltarin F, Astanina E, Wolanska KI, Morgan MR, Humphries MJ, Santoro MM, Serini G, Valdembri D.

Nat Commun. 2016 Nov 23;7:13546. doi: 10.1038/ncomms13546.

6.

Class 3 semaphorins in cardiovascular development.

Valdembri D, Regano D, Maione F, Giraudo E, Serini G.

Cell Adh Migr. 2016 Nov;10(6):641-651. Epub 2016 Jul 20. Review.

7.

Peritoneal and hematogenous metastases of ovarian cancer cells are both controlled by the p90RSK through a self-reinforcing cell autonomous mechanism.

Torchiaro E, Lorenzato A, Olivero M, Valdembri D, Gagliardi PA, Gai M, Erriquez J, Serini G, Di Renzo MF.

Oncotarget. 2016 Jan 5;7(1):712-28. doi: 10.18632/oncotarget.6412.

8.

Linifanib: current status and future potential in cancer therapy.

Aversa C, Leone F, Zucchini G, Serini G, Geuna E, Milani A, Valdembri D, Martinello R, Montemurro F.

Expert Rev Anticancer Ther. 2015 Jun;15(6):677-87. doi: 10.1586/14737140.2015.1042369. Epub 2015 May 2. Review.

PMID:
25936222
9.

Tivantinib (ARQ197) displays cytotoxic activity that is independent of its ability to bind MET.

Basilico C, Pennacchietti S, Vigna E, Chiriaco C, Arena S, Bardelli A, Valdembri D, Serini G, Michieli P.

Clin Cancer Res. 2013 May 1;19(9):2381-92. doi: 10.1158/1078-0432.CCR-12-3459. Epub 2013 Mar 26.

10.

Regulation of adhesion site dynamics by integrin traffic.

Valdembri D, Serini G.

Curr Opin Cell Biol. 2012 Oct;24(5):582-91. doi: 10.1016/j.ceb.2012.08.004. Epub 2012 Sep 13. Review.

PMID:
22981739
11.

The R-Ras/RIN2/Rab5 complex controls endothelial cell adhesion and morphogenesis via active integrin endocytosis and Rac signaling.

Sandri C, Caccavari F, Valdembri D, Camillo C, Veltel S, Santambrogio M, Lanzetti L, Bussolino F, Ivaska J, Serini G.

Cell Res. 2012 Oct;22(10):1479-501. doi: 10.1038/cr.2012.110. Epub 2012 Jul 24.

12.

Regulation of integrins by conformation and traffic: it takes two to tango.

Valdembri D, Sandri C, Santambrogio M, Serini G.

Mol Biosyst. 2011 Sep;7(9):2539-46. doi: 10.1039/c1mb05066d. Epub 2011 Jul 15. Review.

PMID:
21761076
13.

Increasing traffic on vascular routes.

Santambrogio M, Valdembri D, Serini G.

Mol Aspects Med. 2011 Apr;32(2):112-22. doi: 10.1016/j.mam.2011.04.003. Epub 2011 Apr 23. Review.

PMID:
21536065
14.

Angiogenesis: a balancing act between integrin activation and inhibition?

Bussolino F, Caccavari F, Valdembri D, Serini G.

Eur Cytokine Netw. 2009 Dec;20(4):191-6. doi: 10.1684/ecn.2009.0168. Review.

15.

Integrin signaling and lung cancer.

Caccavari F, Valdembri D, Sandri C, Bussolino F, Serini G.

Cell Adh Migr. 2010 Jan-Mar;4(1):124-9. Epub 2010 Jan 16. Review.

16.

Neuropilin-1/GIPC1 signaling regulates alpha5beta1 integrin traffic and function in endothelial cells.

Valdembri D, Caswell PT, Anderson KI, Schwarz JP, König I, Astanina E, Caccavari F, Norman JC, Humphries MJ, Bussolino F, Serini G.

PLoS Biol. 2009 Jan 27;7(1):e25. doi: 10.1371/journal.pbio.1000025.

17.

Microenvironment drives the endothelial or neural fate of differentiating embryonic stem cells coexpressing neuropilin-1 and Flk-1.

Gualandris A, Noghero A, Geuna M, Arese M, Valdembri D, Serini G, Bussolino F.

FASEB J. 2009 Jan;23(1):68-78. doi: 10.1096/fj.08-112847. Epub 2008 Aug 29.

PMID:
18757501
18.

AP-2alpha and AP-2gamma regulate tumor progression via specific genetic programs.

Orso F, Penna E, Cimino D, Astanina E, Maione F, Valdembri D, Giraudo E, Serini G, Sismondi P, De Bortoli M, Taverna D.

FASEB J. 2008 Aug;22(8):2702-14. doi: 10.1096/fj.08-106492. Epub 2008 Apr 28.

PMID:
18443366
19.

Semaphoring vascular morphogenesis.

Bussolino F, Valdembri D, Caccavari F, Serini G.

Endothelium. 2006 Mar-Apr;13(2):81-91. Review.

PMID:
16728327
20.

Gorham-Stout syndrome: a monocyte-mediated cytokine propelled disease.

Colucci S, Taraboletti G, Primo L, Viale A, Roca C, Valdembri D, Geuna M, Pagano M, Grano M, Pogrel AM, Harris AL, Athanasou NN, Mantovani A, Zallone A, Bussolino F.

J Bone Miner Res. 2006 Feb;21(2):207-18. Epub 2005 Oct 31.

21.

Integrins and angiogenesis: a sticky business.

Serini G, Valdembri D, Bussolino F.

Exp Cell Res. 2006 Mar 10;312(5):651-8. Epub 2005 Dec 2. Review.

PMID:
16325811
22.

Sema4D induces angiogenesis through Met recruitment by Plexin B1.

Conrotto P, Valdembri D, Corso S, Serini G, Tamagnone L, Comoglio PM, Bussolino F, Giordano S.

Blood. 2005 Jun 1;105(11):4321-9. Epub 2005 Jan 4.

PMID:
15632204
23.

Inhibition of vascular endothelial growth factor receptor 2-mediated endothelial cell activation by Axl tyrosine kinase receptor.

Gallicchio M, Mitola S, Valdembri D, Fantozzi R, Varnum B, Avanzi GC, Bussolino F.

Blood. 2005 Mar 1;105(5):1970-6. Epub 2004 Oct 26.

PMID:
15507525
24.

Aminopeptidase A is a functional target in angiogenic blood vessels.

Marchiò S, Lahdenranta J, Schlingemann RO, Valdembri D, Wesseling P, Arap MA, Hajitou A, Ozawa MG, Trepel M, Giordano RJ, Nanus DM, Dijkman HB, Oosterwijk E, Sidman RL, Cooper MD, Bussolino F, Pasqualini R, Arap W.

Cancer Cell. 2004 Feb;5(2):151-62.

25.

CCL16 activates an angiogenic program in vascular endothelial cells.

Strasly M, Doronzo G, Cappello P, Valdembri D, Arese M, Mitola S, Moore P, Alessandri G, Giovarelli M, Bussolino F.

Blood. 2004 Jan 1;103(1):40-9. Epub 2003 Sep 4. Erratum in: Blood. 2008 Sep 1;112(5):2170.. Correct Capello to Cappello..

26.

Class 3 semaphorins control vascular morphogenesis by inhibiting integrin function.

Serini G, Valdembri D, Zanivan S, Morterra G, Burkhardt C, Caccavari F, Zammataro L, Primo L, Tamagnone L, Logan M, Tessier-Lavigne M, Taniguchi M, Püschel AW, Bussolino F.

Nature. 2003 Jul 24;424(6947):391-7. Erratum in: Nature. 2003 Aug 21;424(6951):974.

PMID:
12879061
27.

Hyperthermia inhibits angiogenesis by a plasminogen activator inhibitor 1-dependent mechanism.

Roca C, Primo L, Valdembri D, Cividalli A, Declerck P, Carmeliet P, Gabriele P, Bussolino F.

Cancer Res. 2003 Apr 1;63(7):1500-7. Erratum in: Cancer Res. 2003 May 1;63(9):2345.

28.

Recombinant AAV vector encoding human VEGF165 enhances wound healing.

Deodato B, Arsic N, Zentilin L, Galeano M, Santoro D, Torre V, Altavilla D, Valdembri D, Bussolino F, Squadrito F, Giacca M.

Gene Ther. 2002 Jun;9(12):777-85.

29.

HIV protease inhibitors are potent anti-angiogenic molecules and promote regression of Kaposi sarcoma.

Sgadari C, Barillari G, Toschi E, Carlei D, Bacigalupo I, Baccarini S, Palladino C, Leone P, Bugarini R, Malavasi L, Cafaro A, Falchi M, Valdembri D, Rezza G, Bussolino F, Monini P, Ensoli B.

Nat Med. 2002 Mar;8(3):225-32.

PMID:
11875492
30.

In vivo activation of JAK2/STAT-3 pathway during angiogenesis induced by GM-CSF.

Valdembri D, Serini G, Vacca A, Ribatti D, Bussolino F.

FASEB J. 2002 Feb;16(2):225-7. Epub 2001 Dec 14.

PMID:
11744626

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