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Items: 1 to 50 of 140

1.

Isolation and Chemical Characterization of Chondroitin Sulfate from Cartilage By-Products of Blackmouth Catshark (Galeus melastomus).

Vázquez JA, Fraguas J, Novoa-Carvallal R, Reis RL, Antelo LT, Pérez-Martín RI, Valcarcel J.

Mar Drugs. 2018 Sep 20;16(10). pii: E344. doi: 10.3390/md16100344.

2.

Corrigendum: Large-scale analysis of genome and transcriptome alterations in multiple tumors unveils novel cancer-relevant splicing networks.

Sebestyén E, Singh B, Miñana B, Pagès A, Mateo F, Pujana MA, Valcárcel J, Eyras E.

Genome Res. 2018 Sep;28(9):1426. doi: 10.1101/gr.242214.118. No abstract available.

3.

Elisa Izaurralde 1959-2018.

Hentze MW, Valcárcel J.

Nat Struct Mol Biol. 2018 Jul;25(7):547. doi: 10.1038/s41594-018-0081-1. No abstract available.

PMID:
29915387
4.

Impaired Spermatogenesis, Muscle, and Erythrocyte Function in U12 Intron Splicing-Defective Zrsr1 Mutant Mice.

Horiuchi K, Perez-Cerezales S, Papasaikas P, Ramos-Ibeas P, López-Cardona AP, Laguna-Barraza R, Fonseca Balvís N, Pericuesta E, Fernández-González R, Planells B, Viera A, Suja JA, Ross PJ, Alén F, Orio L, Rodriguez de Fonseca F, Pintado B, Valcárcel J, Gutiérrez-Adán A.

Cell Rep. 2018 Apr 3;23(1):143-155. doi: 10.1016/j.celrep.2018.03.028.

5.

Systems analysis identifies melanoma-enriched pro-oncogenic networks controlled by the RNA binding protein CELF1.

Cifdaloz M, Osterloh L, Graña O, Riveiro-Falkenbach E, Ximénez-Embún P, Muñoz J, Tejedo C, Calvo TG, Karras P, Olmeda D, Miñana B, Gómez-López G, Cañon E, Eyras E, Guo H, Kappes F, Ortiz-Romero PL, Rodríguez-Peralto JL, Megías D, Valcárcel J, Soengas MS.

Nat Commun. 2017 Dec 21;8(1):2249. doi: 10.1038/s41467-017-02353-y.

6.

Molecular basis of differential 3' splice site sensitivity to anti-tumor drugs targeting U2 snRNP.

Vigevani L, Gohr A, Webb T, Irimia M, Valcárcel J.

Nat Commun. 2017 Dec 13;8(1):2100. doi: 10.1038/s41467-017-02007-z.

7.

Perceived Stress among French Dental Students and Their Opinion about Education Curriculum and Pedagogy.

Inquimbert C, Tramini P, Alsina I, Valcarcel J, Giraudeau N.

J Int Soc Prev Community Dent. 2017 Oct;7(Suppl 2):S92-S98. doi: 10.4103/jispcd.JISPCD_257_17. Epub 2017 Oct 30.

8.

Optimization of high purity chitin and chitosan production from Illex argentinus pens by a combination of enzymatic and chemical processes.

Vázquez JA, Noriega D, Ramos P, Valcarcel J, Novoa-Carballal R, Pastrana L, Reis RL, Pérez-Martín RI.

Carbohydr Polym. 2017 Oct 15;174:262-272. doi: 10.1016/j.carbpol.2017.06.070. Epub 2017 Jun 20.

PMID:
28821067
9.

Glycosaminoglycans from marine sources as therapeutic agents.

Valcarcel J, Novoa-Carballal R, Pérez-Martín RI, Reis RL, Vázquez JA.

Biotechnol Adv. 2017 Nov 1;35(6):711-725. doi: 10.1016/j.biotechadv.2017.07.008. Epub 2017 Jul 21. Review.

PMID:
28739506
10.
11.

Teledentistry, new oral care tool for prisoners.

Giraudeau N, Inquimbert C, Delafoy R, Tramini P, Valcarcel J, Meroueh F.

Int J Prison Health. 2017 Jun 12;13(2):124-134. doi: 10.1108/IJPH-04-2016-0011.

PMID:
28581375
12.

Sudemycin K: A Synthetic Antitumor Splicing Inhibitor Variant with Improved Activity and Versatile Chemistry.

Makowski K, Vigevani L, Albericio F, Valcárcel J, Álvarez M.

ACS Chem Biol. 2017 Jan 20;12(1):163-173. doi: 10.1021/acschembio.6b00562. Epub 2016 Dec 1.

PMID:
28103691
13.

Structural basis for the recognition of spliceosomal SmN/B/B' proteins by the RBM5 OCRE domain in splicing regulation.

Mourão A, Bonnal S, Soni K, Warner L, Bordonné R, Valcárcel J, Sattler M.

Elife. 2016 Nov 29;5. pii: e14707. doi: 10.7554/eLife.14707.

14.

Viral cell biology: Influenza raids the splicing store.

Valcárcel J, Ortín J.

Nat Microbiol. 2016 Jun 24;1(7):16100. doi: 10.1038/nmicrobiol.2016.100. No abstract available.

PMID:
27572980
15.

Correction to: The Spliceosome: The Ultimate RNA Chaperone and Sculptor: [Trends in Biochemical Sciences, January 2016, Vol 41, No. 1, 33-45].

Papasaikas P, Valcárcel J.

Trends Biochem Sci. 2016 Apr;41(4):386. doi: 10.1016/j.tibs.2015.12.010. Epub 2016 Jan 20. No abstract available.

PMID:
27307312
16.

Large-scale analysis of genome and transcriptome alterations in multiple tumors unveils novel cancer-relevant splicing networks.

Sebestyén E, Singh B, Miñana B, Pagès A, Mateo F, Pujana MA, Valcárcel J, Eyras E.

Genome Res. 2016 Jun;26(6):732-44. doi: 10.1101/gr.199935.115. Epub 2016 Apr 13. Erratum in: Genome Res. 2018 Sep;28(9):1426.

17.

The complete local genotype-phenotype landscape for the alternative splicing of a human exon.

Julien P, Miñana B, Baeza-Centurion P, Valcárcel J, Lehner B.

Nat Commun. 2016 May 10;7:11558. doi: 10.1038/ncomms11558.

18.

Erratum to: Promoter-like epigenetic signatures in exons displaying cell type-specific splicing.

Curado J, Iannone C, Tilgner H, Valcárcel J, Guigó R.

Genome Biol. 2016 Mar 18;17:52. doi: 10.1186/s13059-016-0890-7. No abstract available.

19.

Tumor suppressor properties of the splicing regulatory factor RBM10.

Hernández J, Bechara E, Schlesinger D, Delgado J, Serrano L, Valcárcel J.

RNA Biol. 2016;13(4):466-72. doi: 10.1080/15476286.2016.1144004.

20.

The Spliceosome: The Ultimate RNA Chaperone and Sculptor.

Papasaikas P, Valcárcel J.

Trends Biochem Sci. 2016 Jan;41(1):33-45. doi: 10.1016/j.tibs.2015.11.003. Epub 2015 Dec 9. Review. Erratum in: Trends Biochem Sci. 2016 Apr;41(4):386.

PMID:
26682498
21.

Quantitative evaluation of alternatively spliced mRNA isoforms by label-free real-time plasmonic sensing.

Huertas CS, Carrascosa LG, Bonnal S, Valcárcel J, Lechuga LM.

Biosens Bioelectron. 2016 Apr 15;78:118-125. doi: 10.1016/j.bios.2015.11.023. Epub 2015 Nov 10.

PMID:
26599481
22.

The pathogenicity of splicing defects: mechanistic insights into pre-mRNA processing inform novel therapeutic approaches.

Daguenet E, Dujardin G, Valcárcel J.

EMBO Rep. 2015 Dec;16(12):1640-55. doi: 10.15252/embr.201541116. Epub 2015 Nov 13. Review.

23.

Promoter-like epigenetic signatures in exons displaying cell type-specific splicing.

Curado J, Iannone C, Tilgner H, Valcárcel J, Guigó R.

Genome Biol. 2015 Oct 23;16:236. doi: 10.1186/s13059-015-0797-8. Erratum in: Genome Biol. 2016;17(1):52.

24.

Reconstruction of composite regulator-target splicing networks from high-throughput transcriptome data.

Papasaikas P, Rao A, Huggins P, Valcarcel J, Lopez A.

BMC Genomics. 2015;16 Suppl 10:S7. doi: 10.1186/1471-2164-16-S10-S7. Epub 2015 Oct 2.

25.

Pseudomonas aeruginosa and Achromobacter sp. clonal selection leads to successive waves of contamination of water in dental care units.

Abdouchakour F, Dupont C, Grau D, Aujoulat F, Mournetas P, Marchandin H, Parer S, Gibert P, Valcarcel J, Jumas-Bilak E.

Appl Environ Microbiol. 2015 Nov;81(21):7509-24. doi: 10.1128/AEM.01279-15. Epub 2015 Aug 21.

26.

Corrigendum: Relationship between nucleosome positioning and progesterone-induced alternative splicing in breast cancer cells.

Iannone C, Pohl A, Papasaikas P, Soronellas D, Vicent GP, Beato M, Valcárcel J.

RNA. 2015 Jul;21(7):1390. No abstract available.

27.

Role of six single nucleotide polymorphisms, risk factors in coronary disease, in OLR1 alternative splicing.

Tejedor JR, Tilgner H, Iannone C, Guigó R, Valcárcel J.

RNA. 2015 Jun;21(6):1187-202. doi: 10.1261/rna.049890.115. Epub 2015 Apr 22.

29.

Relationship between nucleosome positioning and progesterone-induced alternative splicing in breast cancer cells.

Iannone C, Pohl A, Papasaikas P, Soronellas D, Vicent GP, Beato M, ValcáRcel J.

RNA. 2015 Mar;21(3):360-74. Erratum in: RNA. 2015 Jul;21(7):1390.

30.

RNA. Prescribing splicing.

Guigó R, Valcárcel J.

Science. 2015 Jan 9;347(6218):124-5. doi: 10.1126/science.aaa4864. No abstract available.

31.

Outcomes after stroke thrombolysis according to prior antiplatelet use.

Meseguer E, Labreuche J, Guidoux C, Lavallée PC, Cabrejo L, Sirimarco G, Valcarcel JG, Klein IF, Amarenco P, Mazighi M.

Int J Stroke. 2015 Feb;10(2):163-9. doi: 10.1111/ijs.12421. Epub 2014 Dec 8. Review.

PMID:
25487908
32.

Functional splicing network reveals extensive regulatory potential of the core spliceosomal machinery.

Papasaikas P, Tejedor JR, Vigevani L, Valcárcel J.

Mol Cell. 2015 Jan 8;57(1):7-22. doi: 10.1016/j.molcel.2014.10.030. Epub 2014 Dec 4.

33.

Genome-wide identification of Fas/CD95 alternative splicing regulators reveals links with iron homeostasis.

Tejedor JR, Papasaikas P, Valcárcel J.

Mol Cell. 2015 Jan 8;57(1):23-38. doi: 10.1016/j.molcel.2014.10.029. Epub 2014 Dec 4.

34.

Argonaute-1 binds transcriptional enhancers and controls constitutive and alternative splicing in human cells.

Alló M, Agirre E, Bessonov S, Bertucci P, Gómez Acuña L, Buggiano V, Bellora N, Singh B, Petrillo E, Blaustein M, Miñana B, Dujardin G, Pozzi B, Pelisch F, Bechara E, Agafonov DE, Srebrow A, Lührmann R, Valcárcel J, Eyras E, Kornblihtt AR.

Proc Natl Acad Sci U S A. 2014 Nov 4;111(44):15622-9. doi: 10.1073/pnas.1416858111. Epub 2014 Oct 13.

35.

Splicing together sister chromatids.

Valcárcel J, Malumbres M.

EMBO J. 2014 Nov 18;33(22):2601-3. doi: 10.15252/embj.201489988. Epub 2014 Sep 29.

36.

Co-option of the piRNA pathway for germline-specific alternative splicing of C. elegans TOR.

Barberán-Soler S, Fontrodona L, Ribó A, Lamm AT, Iannone C, Cerón J, Lehner B, Valcárcel J.

Cell Rep. 2014 Sep 25;8(6):1609-1616. doi: 10.1016/j.celrep.2014.08.016. Epub 2014 Sep 15.

37.

Molecular biology. A splicing magic bullet.

Vigevani L, Valcárcel J.

Science. 2014 Aug 8;345(6197):624-5. doi: 10.1126/science.1258444. No abstract available.

PMID:
25104373
38.

Regulation of FAS exon definition and apoptosis by the Ewing sarcoma protein.

Paronetto MP, Bernardis I, Volpe E, Bechara E, Sebestyén E, Eyras E, Valcárcel J.

Cell Rep. 2014 May 22;7(4):1211-26. doi: 10.1016/j.celrep.2014.03.077. Epub 2014 May 10.

39.

Effect of genotype and environment on the glycoalkaloid content of rare, heritage, and commercial potato varieties.

Valcarcel J, Reilly K, Gaffney M, O'Brien N.

J Food Sci. 2014 May;79(5):T1039-48. doi: 10.1111/1750-3841.12443. Epub 2014 Apr 2.

PMID:
24697731
40.

Structure, dynamics and RNA binding of the multi-domain splicing factor TIA-1.

Wang I, Hennig J, Jagtap PK, Sonntag M, Valcárcel J, Sattler M.

Nucleic Acids Res. 2014 May;42(9):5949-66. doi: 10.1093/nar/gku193. Epub 2014 Mar 25.

41.

Synonymous mutations frequently act as driver mutations in human cancers.

Supek F, Miñana B, Valcárcel J, Gabaldón T, Lehner B.

Cell. 2014 Mar 13;156(6):1324-1335. doi: 10.1016/j.cell.2014.01.051.

42.

RBM5, 6, and 10 differentially regulate NUMB alternative splicing to control cancer cell proliferation.

Bechara EG, Sebestyén E, Bernardis I, Eyras E, Valcárcel J.

Mol Cell. 2013 Dec 12;52(5):720-33. doi: 10.1016/j.molcel.2013.11.010.

43.

RNAtomy of the Spliceosome's heart.

Bonnal S, Valcárcel J.

EMBO J. 2013 Oct 30;32(21):2785-7. doi: 10.1038/emboj.2013.213. Epub 2013 Sep 24. No abstract available.

44.

Competition by the masses.

Bechara E, Valcárcel J.

Mol Cell. 2013 Aug 8;51(3):279-80. doi: 10.1016/j.molcel.2013.07.018.

45.

Chromatin's thread to alternative splicing regulation.

Iannone C, Valcárcel J.

Chromosoma. 2013 Dec;122(6):465-74. doi: 10.1007/s00412-013-0425-x. Epub 2013 Aug 3. Review.

PMID:
23912688
46.

In vitro correction of a pseudoexon-generating deep intronic mutation in LGMD2A by antisense oligonucleotides and modified small nuclear RNAs.

Blázquez L, Aiastui A, Goicoechea M, Martins de Araujo M, Avril A, Beley C, García L, Valcárcel J, Fortes P, López de Munain A.

Hum Mutat. 2013 Oct;34(10):1387-95. doi: 10.1002/humu.22379. Epub 2013 Aug 7.

PMID:
23864287
47.

Isolated pseudo-RNA-recognition motifs of SR proteins can regulate splicing using a noncanonical mode of RNA recognition.

Cléry A, Sinha R, Anczuków O, Corrionero A, Moursy A, Daubner GM, Valcárcel J, Krainer AR, Allain FH.

Proc Natl Acad Sci U S A. 2013 Jul 23;110(30):E2802-11. doi: 10.1073/pnas.1303445110. Epub 2013 Jul 8.

48.

[Oral health and precariousness in pregnant women].

Delemotte M, Valcarcel J, Tramini P.

Odontostomatol Trop. 2013 Mar;36(141):14-26. French.

PMID:
23781682
49.

CPEB1 coordinates alternative 3'-UTR formation with translational regulation.

Bava FA, Eliscovich C, Ferreira PG, Miñana B, Ben-Dov C, Guigó R, Valcárcel J, Méndez R.

Nature. 2013 Mar 7;495(7439):121-5. doi: 10.1038/nature11901. Epub 2013 Feb 24.

PMID:
23434754
50.

Evolution. Splicing in 4D.

Papasaikas P, Valcárcel J.

Science. 2012 Dec 21;338(6114):1547-8. doi: 10.1126/science.1233219. No abstract available.

PMID:
23258879

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