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Items: 34

1.

Entry of Polarized Effector Cells into Quiescence Forces HIV Latency.

Dobrowolski C, Valadkhan S, Graham AC, Shukla M, Ciuffi A, Telenti A, Karn J.

MBio. 2019 Mar 26;10(2). pii: e00337-19. doi: 10.1128/mBio.00337-19.

2.

The lncRNA BORG facilitates the survival and chemoresistance of triple-negative breast cancers.

Gooding AJ, Zhang B, Gunawardane L, Beard A, Valadkhan S, Schiemann WP.

Oncogene. 2019 Mar;38(12):2020-2041. doi: 10.1038/s41388-018-0586-4. Epub 2018 Nov 22.

3.
4.

Estrogen receptor-1 is a key regulator of HIV-1 latency that imparts gender-specific restrictions on the latent reservoir.

Das B, Dobrowolski C, Luttge B, Valadkhan S, Chomont N, Johnston R, Bacchetti P, Hoh R, Gandhi M, Deeks SG, Scully E, Karn J.

Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):E7795-E7804. doi: 10.1073/pnas.1803468115. Epub 2018 Jul 30.

5.

Regulation of the Interferon Response by lncRNAs in HCV Infection.

Valadkhan S, Fortes P.

Front Microbiol. 2018 Feb 16;9:181. doi: 10.3389/fmicb.2018.00181. eCollection 2018. Review.

6.

The lncRNA BORG Drives Breast Cancer Metastasis and Disease Recurrence.

Gooding AJ, Zhang B, Jahanbani FK, Gilmore HL, Chang JC, Valadkhan S, Schiemann WP.

Sci Rep. 2017 Oct 5;7(1):12698. doi: 10.1038/s41598-017-12716-6.

7.

Immortalization of primary microglia: a new platform to study HIV regulation in the central nervous system.

Garcia-Mesa Y, Jay TR, Checkley MA, Luttge B, Dobrowolski C, Valadkhan S, Landreth GE, Karn J, Alvarez-Carbonell D.

J Neurovirol. 2017 Feb;23(1):47-66. doi: 10.1007/s13365-016-0499-3. Epub 2016 Nov 21.

8.

lncRNAs in Stress Response.

Valadkhan S, Valencia-HipĆ³lito A.

Curr Top Microbiol Immunol. 2016;394:203-36. doi: 10.1007/82_2015_489. Review.

PMID:
26658944
9.

lncRNA-mediated regulation of the interferon response.

Valadkhan S, Gunawardane LS.

Virus Res. 2016 Jan 2;212:127-36. doi: 10.1016/j.virusres.2015.09.023. Epub 2015 Oct 22. Review.

10.

Regulation of Interferon-Stimulated Gene BST2 by a lncRNA Transcribed from a Shared Bidirectional Promoter.

Kambara H, Gunawardane L, Zebrowski E, Kostadinova L, Jobava R, Krokowski D, Hatzoglou M, Anthony DD, Valadkhan S.

Front Immunol. 2015 Jan 30;5:676. doi: 10.3389/fimmu.2014.00676. eCollection 2014.

11.

Negative regulation of the interferon response by an interferon-induced long non-coding RNA.

Kambara H, Niazi F, Kostadinova L, Moonka DK, Siegel CT, Post AB, Carnero E, Barriocanal M, Fortes P, Anthony DD, Valadkhan S.

Nucleic Acids Res. 2014;42(16):10668-80. doi: 10.1093/nar/gku713. Epub 2014 Aug 13.

12.

A novel RNA motif mediates the strict nuclear localization of a long noncoding RNA.

Zhang B, Gunawardane L, Niazi F, Jahanbani F, Chen X, Valadkhan S.

Mol Cell Biol. 2014 Jun;34(12):2318-29. doi: 10.1128/MCB.01673-13. Epub 2014 Apr 14.

13.

The role of snRNAs in spliceosomal catalysis.

Valadkhan S.

Prog Mol Biol Transl Sci. 2013;120:195-228. doi: 10.1016/B978-0-12-381286-5.00006-8.

PMID:
24156945
14.

Role of small nuclear RNAs in eukaryotic gene expression.

Valadkhan S, Gunawardane LS.

Essays Biochem. 2013;54:79-90. doi: 10.1042/bse0540079. Review.

PMID:
23829528
15.

Computational analysis of functional long noncoding RNAs reveals lack of peptide-coding capacity and parallels with 3' UTRs.

Niazi F, Valadkhan S.

RNA. 2012 Apr;18(4):825-43. doi: 10.1261/rna.029520.111. Epub 2012 Feb 23.

16.

A snRNP's ordered path to maturity.

Valadkhan S.

Genes Dev. 2011 Aug 1;25(15):1563-7. doi: 10.1101/gad.17311211.

17.

Splicing of an intervening sequence by protein-free human snRNAs.

Jaladat Y, Zhang B, Mohammadi A, Valadkhan S.

RNA Biol. 2011 May-Jun;8(3):372-7. Epub 2011 May 1.

18.

The spliceosomal proteome: at the heart of the largest cellular ribonucleoprotein machine.

Valadkhan S, Jaladat Y.

Proteomics. 2010 Nov;10(22):4128-41. doi: 10.1002/pmic.201000354. Epub 2010 Nov 2. Review.

19.

Metal binding and substrate positioning by evolutionarily invariant U6 sequences in catalytically active protein-free snRNAs.

Lee C, Jaladat Y, Mohammadi A, Sharifi A, Geisler S, Valadkhan S.

RNA. 2010 Nov;16(11):2226-38. doi: 10.1261/rna.2170910. Epub 2010 Sep 8.

20.

Role of the snRNAs in spliceosomal active site.

Valadkhan S.

RNA Biol. 2010 May-Jun;7(3):345-53. Epub 2010 May 16. Review.

PMID:
20458185
21.

Reprogramming of the non-coding transcriptome during brain development.

Valadkhan S, Nilsen TW.

J Biol. 2010;9(1):5. doi: 10.1186/jbiol197. Epub 2010 Feb 5.

22.

Protein-free small nuclear RNAs catalyze a two-step splicing reaction.

Valadkhan S, Mohammadi A, Jaladat Y, Geisler S.

Proc Natl Acad Sci U S A. 2009 Jul 21;106(29):11901-6. doi: 10.1073/pnas.0902020106. Epub 2009 Jun 22.

23.

The use of simple model systems to study spliceosomal catalysis.

Valadkhan S, Manley JL.

RNA. 2009 Jan;15(1):4-7. doi: 10.1261/rna.1425809. Epub 2008 Nov 24.

24.

Protein-free spliceosomal snRNAs catalyze a reaction that resembles the first step of splicing.

Valadkhan S, Mohammadi A, Wachtel C, Manley JL.

RNA. 2007 Dec;13(12):2300-11. Epub 2007 Oct 16.

25.

The spliceosome: caught in a web of shifting interactions.

Valadkhan S.

Curr Opin Struct Biol. 2007 Jun;17(3):310-5. Epub 2007 Jun 15. Review.

PMID:
17574835
26.

The spliceosome: a ribozyme at heart?

Valadkhan S.

Biol Chem. 2007 Jul;388(7):693-7. Review.

PMID:
17570821
27.

snRNAs as the catalysts of pre-mRNA splicing.

Valadkhan S.

Curr Opin Chem Biol. 2005 Dec;9(6):603-8. Epub 2005 Oct 20. Review.

PMID:
16242989
28.

Qualitative discrepancy between different measures of dynamics in thin polymer films.

Fakhraai Z, Valadkhan S, Forrest JA.

Eur Phys J E Soft Matter. 2005 Oct;18(2):143-8. Epub 2005 Oct 7.

PMID:
16211335
29.

Young Scientist Award essay winner. Construction of a minimal, protein-free spliceosome.

Valadkhan S.

Science. 2005 Feb 11;307(5711):863-4. No abstract available.

30.

Characterization of the catalytic activity of U2 and U6 snRNAs.

Valadkhan S, Manley JL.

RNA. 2003 Jul;9(7):892-904.

31.

Intrinsic metal binding by a spliceosomal RNA.

Valadkhan S, Manley JL.

Nat Struct Biol. 2002 Jul;9(7):498-9. No abstract available. Erratum in: Nat Struct Biol 2002 Sep;9(9):711.

PMID:
12080335
32.

Splicing-related catalysis by protein-free snRNAs.

Valadkhan S, Manley JL.

Nature. 2001 Oct 18;413(6857):701-7.

PMID:
11607023
34.

A UV-crosslinkable interaction in human U6 snRNA.

Sun JS, Valadkhan S, Manley JL.

RNA. 1998 May;4(5):489-97.

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