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Items: 37

1.

Low Expression of miR-18a as a Characteristic of Pediatric Acute Lymphoblastic Leukemia.

Mosakhani N, Missiry ME, Vakkila E, Knuutila S, Vakkila J.

J Pediatr Hematol Oncol. 2017 Nov;39(8):585-588. doi: 10.1097/MPH.0000000000000921.

PMID:
29068867
2.

Comprehensive real-time epidemiological data from respiratory infections in Finland between 2010 and 2014 obtained from an automated and multianalyte mariPOC® respiratory pathogen test.

Gunell M, Antikainen P, Porjo N, Irjala K, Vakkila J, Hotakainen K, Kaukoranta SS, Hirvonen JJ, Saha K, Manninen R, Forsblom B, Rantakokko-Jalava K, Peltola V, Koskinen JO, Huovinen P.

Eur J Clin Microbiol Infect Dis. 2016 Mar;35(3):405-13. doi: 10.1007/s10096-015-2553-0. Epub 2016 Jan 6.

PMID:
26740322
3.

Detection of Group A Streptococcus from Pharyngeal Swab Samples by Bacterial Culture Is Challenged by a Novel mariPOC Point-of-Care Test.

Vakkila J, Koskinen JO, Brandt A, Muotiala A, Liukko V, Soittu S, Meriluoto S, Vesalainen M, Huovinen P, Irjala K.

J Clin Microbiol. 2015 Jul;53(7):2079-83. doi: 10.1128/JCM.00018-15. Epub 2015 Apr 22.

4.

Dasatinib promotes Th1-type responses in granzyme B expressing T-cells.

Kreutzman A, Ilander M, Porkka K, Vakkila J, Mustjoki S.

Oncoimmunology. 2014 May 29;3:e28925. eCollection 2014.

5.

Enlarged memory T-cell pool and enhanced Th1-type responses in chronic myeloid leukemia patients who have successfully discontinued IFN-α monotherapy.

Ilander M, Kreutzman A, Rohon P, Melo T, Faber E, Porkka K, Vakkila J, Mustjoki S.

PLoS One. 2014 Jan 31;9(1):e87794. doi: 10.1371/journal.pone.0087794. eCollection 2014.

6.

Imatinib and pegylated IFN-α2b discontinuation in first-line chronic myeloid leukemia patients following a major molecular response.

Koskenvesa P, Kreutzman A, Rohon P, Pihlman M, Vakkila E, Räsänen A, Vapaatalo M, Remes K, Lundán T, Hjorth-Hansen H, Vakkila J, Simonsson B, Mustjoki S, Porkka K.

Eur J Haematol. 2014;92(5):413-20. doi: 10.1111/ejh.12258. Epub 2014 Jan 28.

PMID:
24372965
7.

Dendritic cells from Crohn's disease patients show aberrant STAT1 and STAT3 signaling.

Nieminen JK, Niemi M, Sipponen T, Salo HM, Klemetti P, Färkkilä M, Vakkila J, Vaarala O.

PLoS One. 2013 Aug 7;8(8):e70738. doi: 10.1371/journal.pone.0070738. eCollection 2013.

8.

The CXCR4-CXCL12 axis in Ewing sarcoma: promotion of tumor growth rather than metastatic disease.

Berghuis D, Schilham MW, Santos SJ, Savola S, Knowles HJ, Dirksen U, Schaefer KL, Vakkila J, Hogendoorn PC, Lankester AC.

Clin Sarcoma Res. 2012 Dec 18;2(1):24. doi: 10.1186/2045-3329-2-24.

9.

Rapid mobilization of cytotoxic lymphocytes induced by dasatinib therapy.

Mustjoki S, Auvinen K, Kreutzman A, Rousselot P, Hernesniemi S, Melo T, Lahesmaa-Korpinen AM, Hautaniemi S, Bouchet S, Molimard M, Smykla R, Lee FY, Vakkila J, Jalkanen S, Salmi M, Porkka K.

Leukemia. 2013 Apr;27(4):914-24. doi: 10.1038/leu.2012.348. Epub 2012 Nov 29.

PMID:
23192016
10.

The presence of sinusoidal CD163(+) macrophages in lymph nodes is associated with favorable nodal status in patients with breast cancer.

Mansfield AS, Heikkila P, von Smitten K, Vakkila J, Leidenius M.

Virchows Arch. 2012 Dec;461(6):639-46. doi: 10.1007/s00428-012-1338-4. Epub 2012 Nov 13.

PMID:
23149573
11.

Altered phenotype of peripheral blood dendritic cells in pediatric type 1 diabetes.

Nieminen JK, Vakkila J, Salo HM, Ekström N, Härkönen T, Ilonen J, Knip M, Vaarala O.

Diabetes Care. 2012 Nov;35(11):2303-10. doi: 10.2337/dc11-2460. Epub 2012 Jul 11.

12.

High Expression of Complement Component 5 (C5) at Tumor Site Associates with Superior Survival in Ewing's Sarcoma Family of Tumour Patients.

Savola S, Klami A, Myllykangas S, Manara C, Scotlandi K, Picci P, Knuutila S, Vakkila J.

ISRN Oncol. 2011;2011:168712. doi: 10.5402/2011/168712. Epub 2011 Oct 2.

13.

Metastasis to sentinel lymph nodes in breast cancer is associated with maturation arrest of dendritic cells and poor co-localization of dendritic cells and CD8+ T cells.

Mansfield AS, Heikkila P, von Smitten K, Vakkila J, Leidenius M.

Virchows Arch. 2011 Oct;459(4):391-8. doi: 10.1007/s00428-011-1145-3. Epub 2011 Sep 6.

PMID:
21894561
14.

Chronic myeloid leukemia patients in prolonged remission following interferon-α monotherapy have distinct cytokine and oligoclonal lymphocyte profile.

Kreutzman A, Rohon P, Faber E, Indrak K, Juvonen V, Kairisto V, Voglová J, Sinisalo M, Flochová E, Vakkila J, Arstila P, Porkka K, Mustjoki S.

PLoS One. 2011;6(8):e23022. doi: 10.1371/journal.pone.0023022. Epub 2011 Aug 9.

15.

Poor cytokine-induced phosphorylation in chronic myeloid leukemia patients at diagnosis is effectively reversed by tyrosine kinase inhibitor therapy.

Jalkanen SE, Vakkila J, Kreutzman A, Nieminen JK, Porkka K, Mustjoki S.

Exp Hematol. 2011 Jan;39(1):102-113.e1. doi: 10.1016/j.exphem.2010.09.005. Epub 2010 Oct 12.

PMID:
20869423
16.

Simultaneous Foxp3 and IDO expression is associated with sentinel lymph node metastases in breast cancer.

Mansfield AS, Heikkila PS, Vaara AT, von Smitten KA, Vakkila JM, Leidenius MH.

BMC Cancer. 2009 Jul 15;9:231. doi: 10.1186/1471-2407-9-231.

17.

Coordinate NF-kappaB and STAT1 activation promotes development of myeloid type 1 dendritic cells.

Vakkila J, Demarco RA, Lotze MT.

Scand J Immunol. 2008 Mar;67(3):260-9. doi: 10.1111/j.1365-3083.2007.02068.x.

18.

A novel modification of a flow cytometric assay of phosphorylated STAT1 in whole blood monocytes for immunomonitoring of patients on IFN alpha regimen.

Vakkila J, Nieminen U, Siitonen S, Turunen U, Halme L, Nuutinen H, Mustonen H, Puolakkainen P, Färkkilä M, Repo H.

Scand J Immunol. 2008 Jan;67(1):95-102. Epub 2007 Nov 17.

19.
20.

Imaging analysis of STAT1 and NF-kappaB translocation in dendritic cells at the single cell level.

Vakkila J, DeMarco RA, Lotze MT.

Drug Discov Today. 2005 Autumn;Suppl:19-30.

PMID:
23570163
21.

A basis for distinguishing cultured dendritic cells and macrophages in cytospins and fixed sections.

Vakkila J, Lotze MT, Riga C, Jaffe R.

Pediatr Dev Pathol. 2005 Jan-Feb;8(1):43-51. Epub 2005 Feb 21.

PMID:
15717117
22.
23.

Imaging analysis of STAT1 and NF-kappaB translocation in dendritic cells at the single cell level.

Vakkila J, DeMarco RA, Lotze MT.

J Immunol Methods. 2004 Nov;294(1-2):123-34. Epub 2004 Oct 5.

PMID:
15604022
24.

A novel epitope of N-CAM defines precursors of human adherent NK cells.

Li S, Xu J, Makarenkova VP, Tjandrawan T, Vakkila J, Reichert T, Gooding W, Lagenaur CF, Achim CL, Chambers WH, Herberman RB, Whiteside TL, Vujanovic NL.

J Leukoc Biol. 2004 Dec;76(6):1187-99. Epub 2004 Sep 8.

PMID:
15356097
25.

Inflammation and necrosis promote tumour growth.

Vakkila J, Lotze MT.

Nat Rev Immunol. 2004 Aug;4(8):641-8. doi: 10.1038/nri1415. Review. No abstract available.

PMID:
15286730
26.

Dendritic cell subsets in childhood and in children with cancer: relation to age and disease prognosis.

Vakkila J, Thomson AW, Vettenranta K, Sariola H, Saarinen-Pihkala UM.

Clin Exp Immunol. 2004 Mar;135(3):455-61.

27.

[Dendritic cell--the conductor of the orchestra of immunological responses].

Hänninen A, Vakkila J.

Duodecim. 2003;119(8):763-72. Review. Finnish. No abstract available.

PMID:
12806740
28.

[Cancer immunotherapy].

Vakkila J, Pihkala U.

Duodecim. 1999;115(7):785-94. Review. Finnish. No abstract available.

PMID:
11859512
29.

Poor yield of dendritic cell precursors from untreated pediatric cancer.

Vakkila J, Vettenranta K, Sariola H, Saarinen-Pihkala UM.

J Hematother Stem Cell Res. 2001 Dec;10(6):787-93.

PMID:
11798505
30.

Naive CD4+ T cells can be sensitized with IL-7.

Vakkila J, Aystö S, Saarinen-Pihkala UM, Sariola H.

Scand J Immunol. 2001 Nov;54(5):501-5.

31.
32.
35.

[Leukocyte adhesion molecules and their clinical significance].

Hurme M, Jalkanen S, Vakkila J.

Duodecim. 1988;104(19):1507-14. Review. Finnish. No abstract available.

PMID:
2903823
36.

Dendritic cells in human peripheral blood: effective enrichment from the nonadherent cells.

Vakkila J, Lehtonen E, Koskimies S, Hurme M.

Immunol Lett. 1987 Jul;15(3):229-36.

PMID:
3666802
37.

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