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Items: 1 to 50 of 86

1.

Determining the incidence of familiality in ALS: A study of temporal trends in Ireland from 1994 to 2016.

Ryan M, Heverin M, Doherty MA, Davis N, Corr EM, Vajda A, Pender N, McLaughlin R, Hardiman O.

Neurol Genet. 2018 May 18;4(3):e239. doi: 10.1212/NXG.0000000000000239. eCollection 2018 Jun.

2.

Evaluation of targeted and untargeted effects-based monitoring tools to assess impacts of contaminants of emerging concern on fish in the South Platte River, CO.

Ekman DR, Keteles K, Beihoffer J, Cavallin JE, Dahlin K, Davis JM, Jastrow A, Lazorchak JM, Mills MA, Murphy M, Nguyen D, Vajda AM, Villeneuve DL, Winkelman DL, Collette TW.

Environ Pollut. 2018 Aug;239:706-713. doi: 10.1016/j.envpol.2018.04.054. Epub 2018 Apr 30.

PMID:
29715690
3.

Prognosis for patients with amyotrophic lateral sclerosis: development and validation of a personalised prediction model.

Westeneng HJ, Debray TPA, Visser AE, van Eijk RPA, Rooney JPK, Calvo A, Martin S, McDermott CJ, Thompson AG, Pinto S, Kobeleva X, Rosenbohm A, Stubendorff B, Sommer H, Middelkoop BM, Dekker AM, van Vugt JJFA, van Rheenen W, Vajda A, Heverin M, Kazoka M, Hollinger H, Gromicho M, Körner S, Ringer TM, Rödiger A, Gunkel A, Shaw CE, Bredenoord AL, van Es MA, Corcia P, Couratier P, Weber M, Grosskreutz J, Ludolph AC, Petri S, de Carvalho M, Van Damme P, Talbot K, Turner MR, Shaw PJ, Al-Chalabi A, Chiò A, Hardiman O, Moons KGM, Veldink JH, van den Berg LH.

Lancet Neurol. 2018 May;17(5):423-433. doi: 10.1016/S1474-4422(18)30089-9. Epub 2018 Mar 26.

4.

Connectivity-based characterisation of subcortical grey matter pathology in frontotemporal dementia and ALS: a multimodal neuroimaging study.

Bede P, Omer T, Finegan E, Chipika RH, Iyer PM, Doherty MA, Vajda A, Pender N, McLaughlin RL, Hutchinson S, Hardiman O.

Brain Imaging Behav. 2018 Feb 8. doi: 10.1007/s11682-018-9837-9. [Epub ahead of print]

PMID:
29423814
5.

Measuring reliable change in cognition using the Edinburgh Cognitive and Behavioural ALS Screen (ECAS).

Crockford C, Newton J, Lonergan K, Madden C, Mays I, O'Sullivan M, Costello E, Pinto-Grau M, Vajda A, Heverin M, Pender N, Al-Chalabi A, Hardiman O, Abrahams S.

Amyotroph Lateral Scler Frontotemporal Degener. 2018 Feb;19(1-2):65-73. doi: 10.1080/21678421.2017.1407794. Epub 2017 Dec 7.

PMID:
29214872
6.

The occurrence of intersex fishes in Boulder Creek, Colorado, is a recent phenomenon.

Norris DO, Bolden AL, Vajda AM.

Gen Comp Endocrinol. 2017 Dec 2. pii: S0016-6480(17)30610-X. doi: 10.1016/j.ygcen.2017.12.001. [Epub ahead of print]

PMID:
29203388
7.

Characteristic Increases in EEG Connectivity Correlate With Changes of Structural MRI in Amyotrophic Lateral Sclerosis.

Nasseroleslami B, Dukic S, Broderick M, Mohr K, Schuster C, Gavin B, McLaughlin R, Heverin M, Vajda A, Iyer PM, Pender N, Bede P, Lalor EC, Hardiman O.

Cereb Cortex. 2017 Nov 9:1-15. doi: 10.1093/cercor/bhx301. [Epub ahead of print]

PMID:
29136131
8.

Clustering of Neuropsychiatric Disease in First-Degree and Second-Degree Relatives of Patients With Amyotrophic Lateral Sclerosis.

O'Brien M, Burke T, Heverin M, Vajda A, McLaughlin R, Gibbons J, Byrne S, Pinto-Grau M, Elamin M, Pender N, Hardiman O.

JAMA Neurol. 2017 Dec 1;74(12):1425-1430. doi: 10.1001/jamaneurol.2017.2699.

PMID:
29049464
9.

Effects of an Extreme Flood on Trace Elements in River Water-From Urban Stream to Major River Basin.

Barber LB, Paschke SS, Battaglin WA, Douville C, Fitzgerald KC, Keefe SH, Roth DA, Vajda AM.

Environ Sci Technol. 2017 Sep 19;51(18):10344-10356. doi: 10.1021/acs.est.7b01767. Epub 2017 Sep 1.

PMID:
28862461
10.

Mismatch Negativity as an Indicator of Cognitive Sub-Domain Dysfunction in Amyotrophic Lateral Sclerosis.

Iyer PM, Mohr K, Broderick M, Gavin B, Burke T, Bede P, Pinto-Grau M, Pender NP, McLaughlin R, Vajda A, Heverin M, Lalor EC, Hardiman O, Nasseroleslami B.

Front Neurol. 2017 Aug 15;8:395. doi: 10.3389/fneur.2017.00395. eCollection 2017.

11.

The path to specialist multidisciplinary care in amyotrophic lateral sclerosis: A population- based study of consultations, interventions and costs.

Galvin M, Ryan P, Maguire S, Heverin M, Madden C, Vajda A, Normand C, Hardiman O.

PLoS One. 2017 Jun 22;12(6):e0179796. doi: 10.1371/journal.pone.0179796. eCollection 2017.

12.

Amyotrophic lateral sclerosis patient iPSC-derived astrocytes impair autophagy via non-cell autonomous mechanisms.

Madill M, McDonagh K, Ma J, Vajda A, McLoughlin P, O'Brien T, Hardiman O, Shen S.

Mol Brain. 2017 Jun 13;10(1):22. doi: 10.1186/s13041-017-0300-4.

13.

Neuroimaging patterns along the ALS-FTD spectrum: a multiparametric imaging study.

Omer T, Finegan E, Hutchinson S, Doherty M, Vajda A, McLaughlin RL, Pender N, Hardiman O, Bede P.

Amyotroph Lateral Scler Frontotemporal Degener. 2017 Nov;18(7-8):611-623. doi: 10.1080/21678421.2017.1332077. Epub 2017 May 31.

PMID:
28562080
14.

A Cross-sectional population-based investigation into behavioral change in amyotrophic lateral sclerosis: subphenotypes, staging, cognitive predictors, and survival.

Burke T, Pinto-Grau M, Lonergan K, Bede P, O'Sullivan M, Heverin M, Vajda A, McLaughlin RL, Pender N, Hardiman O.

Ann Clin Transl Neurol. 2017 Apr 11;4(5):305-317. doi: 10.1002/acn3.407. eCollection 2017 May.

15.

Genetic testing in ALS: A survey of current practices.

Vajda A, McLaughlin RL, Heverin M, Thorpe O, Abrahams S, Al-Chalabi A, Hardiman O.

Neurology. 2017 Mar 7;88(10):991-999. doi: 10.1212/WNL.0000000000003686. Epub 2017 Feb 3. Review.

16.

Screening for cognitive dysfunction in ALS: validation of the Edinburgh Cognitive and Behavioural ALS Screen (ECAS) using age and education adjusted normative data.

Pinto-Grau M, Burke T, Lonergan K, McHugh C, Mays I, Madden C, Vajda A, Heverin M, Elamin M, Hardiman O, Pender N.

Amyotroph Lateral Scler Frontotemporal Degener. 2017 Feb;18(1-2):99-106. doi: 10.1080/21678421.2016.1249887. Epub 2016 Nov 28.

PMID:
27894201
17.

Identifying behavioural changes in ALS: Validation of the Beaumont Behavioural Inventory (BBI).

Elamin M, Pinto-Grau M, Burke T, Bede P, Rooney J, O'Sullivan M, Lonergan K, Kirby E, Quinlan E, Breen N, Vajda A, Heverin M, Pender N, Hardiman O.

Amyotroph Lateral Scler Frontotemporal Degener. 2017 Feb;18(1-2):68-73. doi: 10.1080/21678421.2016.1248976. Epub 2016 Nov 28.

PMID:
27894191
18.

What does the ALSFRS-R really measure? A longitudinal and survival analysis of functional dimension subscores in amyotrophic lateral sclerosis.

Rooney J, Burke T, Vajda A, Heverin M, Hardiman O.

J Neurol Neurosurg Psychiatry. 2017 May;88(5):381-385. doi: 10.1136/jnnp-2016-314661. Epub 2016 Nov 25.

PMID:
27888187
19.

C9orf72 expansion differentially affects males with spinal onset amyotrophic lateral sclerosis.

Rooney J, Fogh I, Westeneng HJ, Vajda A, McLaughlin R, Heverin M, Jones A, van Eijk R, Calvo A, Mazzini L, Shaw C, Morrison K, Shaw PJ, Robberecht W, Van Damme P, Al-Chalabi A, van den Berg L, Chiò A, Veldink J, Hardiman O.

J Neurol Neurosurg Psychiatry. 2017 Apr;88(4):281. doi: 10.1136/jnnp-2016-314093. Epub 2016 Sep 23.

PMID:
27663272
20.

Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis.

van Rheenen W, Shatunov A, Dekker AM, McLaughlin RL, Diekstra FP, Pulit SL, van der Spek RA, Võsa U, de Jong S, Robinson MR, Yang J, Fogh I, van Doormaal PT, Tazelaar GH, Koppers M, Blokhuis AM, Sproviero W, Jones AR, Kenna KP, van Eijk KR, Harschnitz O, Schellevis RD, Brands WJ, Medic J, Menelaou A, Vajda A, Ticozzi N, Lin K, Rogelj B, Vrabec K, Ravnik-Glavač M, Koritnik B, Zidar J, Leonardis L, Grošelj LD, Millecamps S, Salachas F, Meininger V, de Carvalho M, Pinto S, Mora JS, Rojas-García R, Polak M, Chandran S, Colville S, Swingler R, Morrison KE, Shaw PJ, Hardy J, Orrell RW, Pittman A, Sidle K, Fratta P, Malaspina A, Topp S, Petri S, Abdulla S, Drepper C, Sendtner M, Meyer T, Ophoff RA, Staats KA, Wiedau-Pazos M, Lomen-Hoerth C, Van Deerlin VM, Trojanowski JQ, Elman L, McCluskey L, Basak AN, Tunca C, Hamzeiy H, Parman Y, Meitinger T, Lichtner P, Radivojkov-Blagojevic M, Andres CR, Maurel C, Bensimon G, Landwehrmeyer B, Brice A, Payan CA, Saker-Delye S, Dürr A, Wood NW, Tittmann L, Lieb W, Franke A, Rietschel M, Cichon S, Nöthen MM, Amouyel P, Tzourio C, Dartigues JF, Uitterlinden AG, Rivadeneira F, Estrada K, Hofman A, Curtis C, Blauw HM, van der Kooi AJ, de Visser M, Goris A, Weber M, Shaw CE, Smith BN, Pansarasa O, Cereda C, Del Bo R, Comi GP, D'Alfonso S, Bertolin C, Sorarù G, Mazzini L, Pensato V, Gellera C, Tiloca C, Ratti A, Calvo A, Moglia C, Brunetti M, Arcuti S, Capozzo R, Zecca C, Lunetta C, Penco S, Riva N, Padovani A, Filosto M, Muller B, Stuit RJ; PARALS Registry; SLALOM Group; SLAP Registry; FALS Sequencing Consortium; SLAGEN Consortium; NNIPPS Study Group, Blair I, Zhang K, McCann EP, Fifita JA, Nicholson GA, Rowe DB, Pamphlett R, Kiernan MC, Grosskreutz J, Witte OW, Ringer T, Prell T, Stubendorff B, Kurth I, Hübner CA, Leigh PN, Casale F, Chio A, Beghi E, Pupillo E, Tortelli R, Logroscino G, Powell J, Ludolph AC, Weishaupt JH, Robberecht W, Van Damme P, Franke L, Pers TH, Brown RH, Glass JD, Landers JE, Hardiman O, Andersen PM, Corcia P, Vourc'h P, Silani V, Wray NR, Visscher PM, de Bakker PI, van Es MA, Pasterkamp RJ, Lewis CM, Breen G, Al-Chalabi A, van den Berg LH, Veldink JH.

Nat Genet. 2016 Sep;48(9):1043-8. doi: 10.1038/ng.3622. Epub 2016 Jul 25.

21.

Age-period-cohort analysis of trends in amyotrophic lateral sclerosis incidence.

Tobin K, Gilthorpe MS, Rooney J, Heverin M, Vajda A, Staines A, Hardiman O.

J Neurol. 2016 Oct;263(10):1919-26. doi: 10.1007/s00415-016-8215-z. Epub 2016 Jul 2.

PMID:
27372451
22.

Survival analysis of geospatial factors in the Irish ALS cohort.

Rooney J, Heverin M, Vajda A, Burke T, Galvin M, Tobin K, Elamin M, Staines A, Hardiman O.

Amyotroph Lateral Scler Frontotemporal Degener. 2016 Oct - Nov;17(7-8):555-560. Epub 2016 May 4.

PMID:
27145090
23.

No association between soil constituents and amyotrophic lateral sclerosis relative risk in Ireland.

Rooney J, Vajda A, Heverin M, Crampsie A, Tobin K, McLaughlin R, Staines A, Hardiman O.

Environ Res. 2016 May;147:102-7. doi: 10.1016/j.envres.2016.01.038. Epub 2016 Feb 6.

PMID:
26855128
24.

Patient journey to a specialist amyotrophic lateral sclerosis multidisciplinary clinic: an exploratory study.

Galvin M, Madden C, Maguire S, Heverin M, Vajda A, Staines A, Hardiman O.

BMC Health Serv Res. 2015 Dec 23;15:571. doi: 10.1186/s12913-015-1229-x.

25.

Social deprivation and population density are not associated with small area risk of amyotrophic lateral sclerosis.

Rooney JP, Tobin K, Crampsie A, Vajda A, Heverin M, McLaughlin R, Staines A, Hardiman O.

Environ Res. 2015 Oct;142:141-7. doi: 10.1016/j.envres.2015.06.024. Epub 2015 Jul 2.

PMID:
26142719
26.

Heritability of Amyotrophic Lateral Sclerosis: Insights From Disparate Numbers.

McLaughlin RL, Vajda A, Hardiman O.

JAMA Neurol. 2015 Aug;72(8):857-8. doi: 10.1001/jamaneurol.2014.4049. No abstract available.

PMID:
26029874
27.

Impact of wastewater infrastructure upgrades on the urban water cycle: Reduction in halogenated reaction byproducts following conversion from chlorine gas to ultraviolet light disinfection.

Barber LB, Hladik ML, Vajda AM, Fitzgerald KC, Douville C.

Sci Total Environ. 2015 Oct 1;529:264-74. doi: 10.1016/j.scitotenv.2015.04.112. Epub 2015 May 27.

PMID:
26025637
28.

Perturbation and restoration of the fathead minnow gut microbiome after low-level triclosan exposure.

Narrowe AB, Albuthi-Lantz M, Smith EP, Bower KJ, Roane TM, Vajda AM, Miller CS.

Microbiome. 2015 Mar 3;3:6. doi: 10.1186/s40168-015-0069-6. eCollection 2015.

29.

Spatial cluster analysis of population amyotrophic lateral sclerosis risk in Ireland.

Rooney J, Vajda A, Heverin M, Elamin M, Crampsie A, McLaughlin R, Staines A, Hardiman O.

Neurology. 2015 Apr 14;84(15):1537-44. doi: 10.1212/WNL.0000000000001477. Epub 2015 Mar 13.

PMID:
25770197
30.

Integrated assessment of wastewater treatment plant effluent estrogenicity in the Upper Murray River, Australia, using the native Murray rainbowfish (Melanotaenia fluviatilis).

Vajda AM, Kumar A, Woods M, Williams M, Doan H, Tolsher P, Kookana RS, Barber LB.

Environ Toxicol Chem. 2015 May;34(5):1078-87. doi: 10.1002/etc.2895. Epub 2015 Apr 7.

PMID:
25645549
31.

Homozygosity mapping in an Irish ALS case-control cohort describes local demographic phenomena and points towards potential recessive risk loci.

McLaughlin RL, Kenna KP, Vajda A, Heverin M, Byrne S, Donaghy CG, Cronin S, Bradley DG, Hardiman O.

Genomics. 2015 Apr;105(4):237-41. doi: 10.1016/j.ygeno.2015.01.002. Epub 2015 Jan 23.

32.

Second-generation Irish genome-wide association study for amyotrophic lateral sclerosis.

McLaughlin RL, Kenna KP, Vajda A, Bede P, Elamin M, Cronin S, Donaghy CG, Bradley DG, Hardiman O.

Neurobiol Aging. 2015 Feb;36(2):1221.e7-13. doi: 10.1016/j.neurobiolaging.2014.08.030. Epub 2014 Sep 6.

PMID:
25442119
33.

First-in-class thyrotropin-releasing hormone (TRH)-based compound binds to a pharmacologically distinct TRH receptor subtype in human brain and is effective in neurodegenerative models.

Kelly JA, Boyle NT, Cole N, Slator GR, Colivicchi MA, Stefanini C, Gobbo OL, Scalabrino GA, Ryan SM, Elamin M, Walsh C, Vajda A, Goggin MM, Campbell M, Mash DC, O'Mara SM, Brayden DJ, Callanan JJ, Tipton KF, Della Corte L, Hunter J, O'Boyle KM, Williams CH, Hardiman O.

Neuropharmacology. 2015 Feb;89:193-203. doi: 10.1016/j.neuropharm.2014.09.024. Epub 2014 Sep 30.

PMID:
25281210
34.

Patterns of cerebral and cerebellar white matter degeneration in ALS.

Bede P, Elamin M, Byrne S, McLaughlin RL, Kenna K, Vajda A, Fagan A, Bradley DG, Hardiman O.

J Neurol Neurosurg Psychiatry. 2015 Apr;86(4):468-70. doi: 10.1136/jnnp-2014-308172. Epub 2014 Jul 21. No abstract available.

35.

[Investigation of the compulsive and impulsive behavioral addictions among adolescents].

Vajda A, Láng A, Péley B.

Psychiatr Hung. 2014;29(2):152-7. Hungarian.

PMID:
25041745
36.

An exploratory spatial analysis of ALS incidence in Ireland over 17.5 years (1995-July 2013).

Rooney J, Heverin M, Vajda A, Crampsie A, Tobin K, Byrne S, Staines A, Hardiman O.

PLoS One. 2014 May 27;9(5):e96556. doi: 10.1371/journal.pone.0096556. eCollection 2014.

37.

Laser-induced instabilities in liquid crystal cells with a photosensitive substrate.

Jánossy I, Fodor-Csorba K, Vajda A, Tóth-Katona T.

Phys Rev E Stat Nonlin Soft Matter Phys. 2014 Jan;89(1):012504. Epub 2014 Jan 9.

PMID:
24580243
38.

Basal ganglia involvement in amyotrophic lateral sclerosis.

Bede P, Elamin M, Byrne S, McLaughlin RL, Kenna K, Vajda A, Pender N, Bradley DG, Hardiman O.

Neurology. 2013 Dec 10;81(24):2107-15. doi: 10.1212/01.wnl.0000437313.80913.2c. Epub 2013 Nov 8.

PMID:
24212388
39.

UBQLN2 mutations are not a frequent cause of amyotrophic lateral sclerosis in Ireland.

McLaughlin RL, Kenna KP, Vajda A, Byrne S, Bradley DG, Hardiman O.

Neurobiol Aging. 2014 Jan;35(1):267.e9-11. doi: 10.1016/j.neurobiolaging.2013.07.023. Epub 2013 Aug 21.

PMID:
23973441
40.

A clinical feasibility study to evaluate the safety and efficacy of PEOT/PBT implants for human donor site filling during mosaicplasty.

Bartha L, Hamann D, Pieper J, Péters F, Riesle J, Vajda A, Novak PK, Hangody LR, Vasarhelyi G, Bodó L, van Blitterswijk C, de Wijn J, Kenyeres A, Modis L, Balo E, Hangody L.

Eur J Orthop Surg Traumatol. 2013 Jan;23(1):81-91. doi: 10.1007/s00590-011-0907-6. Epub 2011 Dec 6.

PMID:
23412412
41.

[The use of Integra dermal regeneration matrix in the surgical treatment of a recurrent, extensive, malignant skin lesion in the temporal region].

Halmy C, Nádai Z, Csőre K, Vajda A, Tamás R.

Orv Hetil. 2013 Feb 10;154(6):225-7. doi: 10.1556/OH.2013.29535. Hungarian.

PMID:
23376690
42.

Gene expression analysis in prostate cancer: the importance of the endogenous control.

Vajda A, Marignol L, Barrett C, Madden SF, Lynch TH, Hollywood D, Perry AS.

Prostate. 2013 Mar;73(4):382-90. doi: 10.1002/pros.22578. Epub 2012 Aug 27.

PMID:
22926970
43.

Fish endocrine disruption responses to a major wastewater treatment facility upgrade.

Barber LB, Vajda AM, Douville C, Norris DO, Writer JH.

Environ Sci Technol. 2012 Feb 21;46(4):2121-31. doi: 10.1021/es202880e. Epub 2012 Feb 2.

PMID:
22300164
44.

Clinical potential of gene-directed enzyme prodrug therapy to improve radiation therapy in prostate cancer patients.

Vajda A, Marignol L, Foley R, Lynch TH, Lawler M, Hollywood D.

Cancer Treat Rev. 2011 Dec;37(8):643-54. doi: 10.1016/j.ctrv.2011.03.003. Epub 2011 Apr 9. Review.

PMID:
21481534
45.

Demasculinization of male fish by wastewater treatment plant effluent.

Vajda AM, Barber LB, Gray JL, Lopez EM, Bolden AM, Schoenfuss HL, Norris DO.

Aquat Toxicol. 2011 Jun;103(3-4):213-21. doi: 10.1016/j.aquatox.2011.02.007. Epub 2011 Feb 18.

PMID:
21473848
46.

[Acute pancreatitis caused by hypertriglyceridemia].

Baranyai T, Terzin V, Vajda A, Wittmann T, Czakó L.

Orv Hetil. 2010 Nov 7;151(45):1869-74. doi: 10.1556/OH.2010.28966. Hungarian.

PMID:
20980226
47.

Antidepressant pharmaceuticals in two U.S. effluent-impacted streams: occurrence and fate in water and sediment, and selective uptake in fish neural tissue.

Schultz MM, Furlong ET, Kolpin DW, Werner SL, Schoenfuss HL, Barber LB, Blazer VS, Norris DO, Vajda AM.

Environ Sci Technol. 2010 Mar 15;44(6):1918-25. doi: 10.1021/es9022706.

PMID:
20121081
48.

Electroconvection in nematic mixtures of bent-core and calamitic molecules.

Tanaka S, Takezoe H, Eber N, Fodor-Csorba K, Vajda A, Buka A.

Phys Rev E Stat Nonlin Soft Matter Phys. 2009 Aug;80(2 Pt 1):021702. Epub 2009 Aug 10.

PMID:
19792141
49.

Antidepressants at environmentally relevant concentrations affect predator avoidance behavior of larval fathead minnows (Pimephales promelas).

Painter MM, Buerkley MA, Julius ML, Vajda AM, Norris DO, Barber LB, Furlong ET, Schultz MM, Schoenfuss HL.

Environ Toxicol Chem. 2009 Dec;28(12):2677-84. doi: 10.1897/08-556.1. Epub 2009 Apr 30.

PMID:
19405782
50.

Predator avoidance performance of larval fathead minnows (Pimephales promelas) following short-term exposure to estrogen mixtures.

McGee MR, Julius ML, Vajda AM, Norris DO, Barber LB, Schoenfuss HL.

Aquat Toxicol. 2009 Mar 9;91(4):355-61. doi: 10.1016/j.aquatox.2008.12.002. Epub 2008 Dec 11.

PMID:
19162341

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