Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 68

1.

The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight.

Garrett-Bakelman FE, Darshi M, Green SJ, Gur RC, Lin L, Macias BR, McKenna MJ, Meydan C, Mishra T, Nasrini J, Piening BD, Rizzardi LF, Sharma K, Siamwala JH, Taylor L, Vitaterna MH, Afkarian M, Afshinnekoo E, Ahadi S, Ambati A, Arya M, Bezdan D, Callahan CM, Chen S, Choi AMK, Chlipala GE, Contrepois K, Covington M, Crucian BE, De Vivo I, Dinges DF, Ebert DJ, Feinberg JI, Gandara JA, George KA, Goutsias J, Grills GS, Hargens AR, Heer M, Hillary RP, Hoofnagle AN, Hook VYH, Jenkinson G, Jiang P, Keshavarzian A, Laurie SS, Lee-McMullen B, Lumpkins SB, MacKay M, Maienschein-Cline MG, Melnick AM, Moore TM, Nakahira K, Patel HH, Pietrzyk R, Rao V, Saito R, Salins DN, Schilling JM, Sears DD, Sheridan CK, Stenger MB, Tryggvadottir R, Urban AE, Vaisar T, Van Espen B, Zhang J, Ziegler MG, Zwart SR, Charles JB, Kundrot CE, Scott GBI, Bailey SM, Basner M, Feinberg AP, Lee SMC, Mason CE, Mignot E, Rana BK, Smith SM, Snyder MP, Turek FW.

Science. 2019 Apr 12;364(6436). pii: eaau8650. doi: 10.1126/science.aau8650.

PMID:
30975860
2.

Erratum. Urine Complement Proteins and the Risk of Kidney Disease Progression and Mortality in Type 2 Diabetes. Diabetes Care 2018;41:2361-2369.

Vaisar T, Durbin-Johnson B, Whitlock K, Babenko I, Mehrotra R, Rocke DM, Afkarian M.

Diabetes Care. 2019 Jun;42(6):1155. doi: 10.2337/dc19-er06a. Epub 2019 Apr 1. No abstract available.

PMID:
30936112
3.

Urine Complement Proteins and the Risk of Kidney Disease Progression and Mortality in Type 2 Diabetes.

Vaisar T, Durbin-Johnson B, Whitlock K, Babenko I, Mehrotra R, Rocke DM, Afkarian M.

Diabetes Care. 2018 Nov;41(11):2361-2369. doi: 10.2337/dc18-0699. Epub 2018 Aug 27. Erratum in: Diabetes Care. 2019 Jun;42(6):1155.

PMID:
30150236
4.

Alteration of HDL Protein Composition with Hemodialysis Initiation.

Wang K, Zelnick LR, Hoofnagle AN, Vaisar T, Henderson CM, Imrey PB, Robinson-Cohen C, de Boer IH, Shiu YT, Himmelfarb J, Beck GJ, Kestenbaum B; HFM Study.

Clin J Am Soc Nephrol. 2018 Aug 7;13(8):1225-1233. doi: 10.2215/CJN.11321017. Epub 2018 Jul 25.

PMID:
30045914
5.

Obesity and Insulin Resistance Promote Atherosclerosis through an IFNγ-Regulated Macrophage Protein Network.

Reardon CA, Lingaraju A, Schoenfelt KQ, Zhou G, Cui C, Jacobs-El H, Babenko I, Hoofnagle A, Czyz D, Shuman H, Vaisar T, Becker L.

Cell Rep. 2018 Jun 5;23(10):3021-3030. doi: 10.1016/j.celrep.2018.05.010.

6.

Sex steroids mediate discrete effects on HDL cholesterol efflux capacity and particle concentration in healthy men.

Rubinow KB, Vaisar T, Chao JH, Heinecke JW, Page ST.

J Clin Lipidol. 2018 Jul - Aug;12(4):1072-1082. doi: 10.1016/j.jacl.2018.04.013. Epub 2018 Apr 30.

PMID:
29793828
7.

Type 2 diabetes is associated with loss of HDL endothelium protective functions.

Vaisar T, Couzens E, Hwang A, Russell M, Barlow CE, DeFina LF, Hoofnagle AN, Kim F.

PLoS One. 2018 Mar 15;13(3):e0192616. doi: 10.1371/journal.pone.0192616. eCollection 2018.

8.

Statin dose reduction with complementary diet therapy: A pilot study of personalized medicine.

Scolaro B, Nogueira MS, Paiva A, Bertolami A, Barroso LP, Vaisar T, Heffron SP, Fisher EA, Castro IA.

Mol Metab. 2018 May;11:137-144. doi: 10.1016/j.molmet.2018.02.005. Epub 2018 Feb 20.

9.

Interactome Screening Identifies the ER Luminal Chaperone Hsp47 as a Regulator of the Unfolded Protein Response Transducer IRE1α.

Sepulveda D, Rojas-Rivera D, Rodríguez DA, Groenendyk J, Köhler A, Lebeaupin C, Ito S, Urra H, Carreras-Sureda A, Hazari Y, Vasseur-Cognet M, Ali MMU, Chevet E, Campos G, Godoy P, Vaisar T, Bailly-Maitre B, Nagata K, Michalak M, Sierralta J, Hetz C.

Mol Cell. 2018 Jan 18;69(2):238-252.e7. doi: 10.1016/j.molcel.2017.12.028.

10.

The Authors Reply.

Vaisar T, Rubinow KB, Hoofnagle AN.

Kidney Int. 2017 Dec;92(6):1556. doi: 10.1016/j.kint.2017.09.001. No abstract available.

11.

Plasminogen promotes cholesterol efflux by the ABCA1 pathway.

Pamir N, Hutchins PM, Ronsein GE, Wei H, Tang C, Das R, Vaisar T, Plow E, Schuster V, Koschinsky ML, Reardon CA, Weinberg R, Dichek DA, Marcovina S, Getz GS, Heinecke JW.

JCI Insight. 2017 Aug 3;2(15). pii: 92176. doi: 10.1172/jci.insight.92176. eCollection 2017 Aug 3.

12.

Kidney function is associated with an altered protein composition of high-density lipoprotein.

Rubinow KB, Henderson CM, Robinson-Cohen C, Himmelfarb J, de Boer IH, Vaisar T, Kestenbaum B, Hoofnagle AN.

Kidney Int. 2017 Dec;92(6):1526-1535. doi: 10.1016/j.kint.2017.05.020. Epub 2017 Jul 26.

13.

Inflammation, remodeling, and other factors affecting HDL cholesterol efflux.

Ronsein GE, Vaisar T.

Curr Opin Lipidol. 2017 Feb;28(1):52-59. doi: 10.1097/MOL.0000000000000382. Review.

14.

Proteome analysis of mast cell releasates reveals a role for chymase in the regulation of coagulation factor XIIIA levels via proteolytic degradation.

Shubin NJ, Glukhova VA, Clauson M, Truong P, Abrink M, Pejler G, White NJ, Deutsch GH, Reeves SR, Vaisar T, James RG, Piliponsky AM.

J Allergy Clin Immunol. 2017 Jan;139(1):323-334. doi: 10.1016/j.jaci.2016.03.051. Epub 2016 May 13.

15.

Concentration of Smaller High-Density Lipoprotein Particle (HDL-P) Is Inversely Correlated With Carotid Intima Media Thickening After Confounder Adjustment: The Multi Ethnic Study of Atherosclerosis (MESA).

Kim DS, Li YK, Bell GA, Burt AA, Vaisar T, Hutchins PM, Furlong CE, Otvos JD, Polak JF, Arnan MK, Kaufman JD, McClelland RL, Longstreth WT Jr, Jarvik GP.

J Am Heart Assoc. 2016 May 20;5(5). pii: e002977. doi: 10.1161/JAHA.115.002977.

16.

Patients With Coronary Endothelial Dysfunction Have Impaired Cholesterol Efflux Capacity and Reduced HDL Particle Concentration.

Monette JS, Hutchins PM, Ronsein GE, Wimberger J, Irwin AD, Tang C, Sara JD, Shao B, Vaisar T, Lerman A, Heinecke JW.

Circ Res. 2016 Jun 24;119(1):83-90. doi: 10.1161/CIRCRESAHA.116.308357. Epub 2016 Apr 25.

17.

Isolating and Quantifying Plasma HDL Proteins by Sequential Density Gradient Ultracentrifugation and Targeted Proteomics.

Henderson CM, Vaisar T, Hoofnagle AN.

Methods Mol Biol. 2016;1410:105-20. doi: 10.1007/978-1-4939-3524-6_7.

18.

Serum amyloid A impairs the antiinflammatory properties of HDL.

Han CY, Tang C, Guevara ME, Wei H, Wietecha T, Shao B, Subramanian S, Omer M, Wang S, O'Brien KD, Marcovina SM, Wight TN, Vaisar T, de Beer MC, de Beer FC, Osborne WR, Elkon KB, Chait A.

J Clin Invest. 2016 Feb;126(2):796. doi: 10.1172/JCI86401. Epub 2016 Feb 1. No abstract available.

19.

Niacin Therapy Increases High-Density Lipoprotein Particles and Total Cholesterol Efflux Capacity But Not ABCA1-Specific Cholesterol Efflux in Statin-Treated Subjects.

Ronsein GE, Hutchins PM, Isquith D, Vaisar T, Zhao XQ, Heinecke JW.

Arterioscler Thromb Vasc Biol. 2016 Feb;36(2):404-11. doi: 10.1161/ATVBAHA.115.306268. Epub 2015 Dec 17.

20.

Proteomic analysis of HDL from inbred mouse strains implicates APOE associated with HDL in reduced cholesterol efflux capacity via the ABCA1 pathway.

Pamir N, Hutchins P, Ronsein G, Vaisar T, Reardon CA, Getz GS, Lusis AJ, Heinecke JW.

J Lipid Res. 2016 Feb;57(2):246-57. doi: 10.1194/jlr.M063701. Epub 2015 Dec 15.

21.

Serum amyloid A impairs the antiinflammatory properties of HDL.

Han CY, Tang C, Guevara ME, Wei H, Wietecha T, Shao B, Subramanian S, Omer M, Wang S, O'Brien KD, Marcovina SM, Wight TN, Vaisar T, de Beer MC, de Beer FC, Osborne WR, Elkon KB, Chait A.

J Clin Invest. 2016 Jan;126(1):266-81. doi: 10.1172/JCI83475. Epub 2015 Dec 7. Erratum in: J Clin Invest. 2016 Feb;126(2):796.

22.

HDL-apolipoprotein A-I exchange is independently associated with cholesterol efflux capacity.

Borja MS, Ng KF, Irwin A, Hong J, Wu X, Isquith D, Zhao XQ, Prazen B, Gildengorin V, Oda MN, Vaisar T.

J Lipid Res. 2015 Oct;56(10):2002-9. doi: 10.1194/jlr.M059865. Epub 2015 Aug 7.

23.

PLTP activity inversely correlates with CAAD: effects of PON1 enzyme activity and genetic variants on PLTP activity.

Kim DS, Burt AA, Ranchalis JE, Vuletic S, Vaisar T, Li WF, Rosenthal EA, Dong W, Eintracht JF, Motulsky AG, Brunzell JD, Albers JJ, Furlong CE, Jarvik GP.

J Lipid Res. 2015 Jul;56(7):1351-62. doi: 10.1194/jlr.P058032. Epub 2015 May 25.

24.

Inflammatory remodeling of the HDL proteome impairs cholesterol efflux capacity.

Vaisar T, Tang C, Babenko I, Hutchins P, Wimberger J, Suffredini AF, Heinecke JW.

J Lipid Res. 2015 Aug;56(8):1519-30. doi: 10.1194/jlr.M059089. Epub 2015 May 20.

25.

Paraoxonase-3 is depleted from the high-density lipoproteins of autoimmune disease patients with subclinical atherosclerosis.

Marsillach J, Becker JO, Vaisar T, Hahn BH, Brunzell JD, Furlong CE, de Boer IH, McMahon MA, Hoofnagle AN; DCCT/EDIC Research Group.

J Proteome Res. 2015 May 1;14(5):2046-54. doi: 10.1021/pr5011586. Epub 2015 Mar 13.

26.

Parallel reaction monitoring (PRM) and selected reaction monitoring (SRM) exhibit comparable linearity, dynamic range and precision for targeted quantitative HDL proteomics.

Ronsein GE, Pamir N, von Haller PD, Kim DS, Oda MN, Jarvik GP, Vaisar T, Heinecke JW.

J Proteomics. 2015 Jan 15;113:388-99. doi: 10.1016/j.jprot.2014.10.017. Epub 2014 Oct 31.

27.

Quantification of HDL particle concentration by calibrated ion mobility analysis.

Hutchins PM, Ronsein GE, Monette JS, Pamir N, Wimberger J, He Y, Anantharamaiah GM, Kim DS, Ranchalis JE, Jarvik GP, Vaisar T, Heinecke JW.

Clin Chem. 2014 Nov;60(11):1393-401. doi: 10.1373/clinchem.2014.228114. Epub 2014 Sep 15.

28.

Macrophage ADAM17 deficiency augments CD36-dependent apoptotic cell uptake and the linked anti-inflammatory phenotype.

Driscoll WS, Vaisar T, Tang J, Wilson CL, Raines EW.

Circ Res. 2013 Jun 21;113(1):52-61. doi: 10.1161/CIRCRESAHA.112.300683. Epub 2013 Apr 12.

29.

Cholesterol accumulation regulates expression of macrophage proteins implicated in proteolysis and complement activation.

Suzuki M, Becker L, Pritchard DK, Gharib SA, Wijsman EM, Bammler TK, Beyer RP, Vaisar T, Oram JF, Heinecke JW.

Arterioscler Thromb Vasc Biol. 2012 Dec;32(12):2910-8. doi: 10.1161/ATVBAHA.112.300383. Epub 2012 Oct 4.

30.

BH3-only proteins are part of a regulatory network that control the sustained signalling of the unfolded protein response sensor IRE1α.

Rodriguez DA, Zamorano S, Lisbona F, Rojas-Rivera D, Urra H, Cubillos-Ruiz JR, Armisen R, Henriquez DR, Cheng EH, Letek M, Vaisar T, Irrazabal T, Gonzalez-Billault C, Letai A, Pimentel-Muiños FX, Kroemer G, Hetz C.

EMBO J. 2012 May 16;31(10):2322-35. doi: 10.1038/emboj.2012.84. Epub 2012 Apr 17.

31.

Testosterone replacement in hypogonadal men alters the HDL proteome but not HDL cholesterol efflux capacity.

Rubinow KB, Vaisar T, Tang C, Matsumoto AM, Heinecke JW, Page ST.

J Lipid Res. 2012 Jul;53(7):1376-83. doi: 10.1194/jlr.P026005. Epub 2012 Apr 13.

32.

Naturally occurring variant of mouse apolipoprotein A-I alters the lipid and HDL association properties of the protein.

Sontag TJ, Carnemolla R, Vaisar T, Reardon CA, Getz GS.

J Lipid Res. 2012 May;53(5):951-63. doi: 10.1194/jlr.M021154. Epub 2012 Mar 8.

33.

Impact of mifepristone, a glucocorticoid/progesterone antagonist, on HDL cholesterol, HDL particle concentration, and HDL function.

Page ST, Krauss RM, Gross C, Ishida B, Heinecke JW, Tang C, Amory JK, Schaefer PM, Cox CJ, Kane J, Purnell JQ, Weinstein RL, Vaisar T.

J Clin Endocrinol Metab. 2012 May;97(5):1598-605. doi: 10.1210/jc.2011-2813. Epub 2012 Mar 7.

34.

Proteomics investigations of HDL: challenges and promise.

Vaisar T.

Curr Vasc Pharmacol. 2012 Jul;10(4):410-21. Review.

35.

Multiple-reaction monitoring-mass spectrometric assays can accurately measure the relative protein abundance in complex mixtures.

Hoofnagle AN, Becker JO, Oda MN, Cavigiolio G, Mayer P, Vaisar T.

Clin Chem. 2012 Apr;58(4):777-81. doi: 10.1373/clinchem.2011.173856. Epub 2012 Feb 3.

36.

Shedding of the Mer tyrosine kinase receptor is mediated by ADAM17 protein through a pathway involving reactive oxygen species, protein kinase Cδ, and p38 mitogen-activated protein kinase (MAPK).

Thorp E, Vaisar T, Subramanian M, Mautner L, Blobel C, Tabas I.

J Biol Chem. 2011 Sep 23;286(38):33335-44. doi: 10.1074/jbc.M111.263020. Epub 2011 Aug 2.

37.

Serum amyloid A facilitates the binding of high-density lipoprotein from mice injected with lipopolysaccharide to vascular proteoglycans.

Chiba T, Chang MY, Wang S, Wight TN, McMillen TS, Oram JF, Vaisar T, Heinecke JW, De Beer FC, De Beer MC, Chait A.

Arterioscler Thromb Vasc Biol. 2011 Jun;31(6):1326-32. doi: 10.1161/ATVBAHA.111.226159. Epub 2011 Apr 7.

38.

High-density lipoprotein suppresses the type I interferon response, a family of potent antiviral immunoregulators, in macrophages challenged with lipopolysaccharide.

Suzuki M, Pritchard DK, Becker L, Hoofnagle AN, Tanimura N, Bammler TK, Beyer RP, Bumgarner R, Vaisar T, de Beer MC, de Beer FC, Miyake K, Oram JF, Heinecke JW.

Circulation. 2010 Nov 9;122(19):1919-27. doi: 10.1161/CIRCULATIONAHA.110.961193. Epub 2010 Oct 25.

39.

Phospholipid transfer protein in human plasma associates with proteins linked to immunity and inflammation.

Cheung MC, Vaisar T, Han X, Heinecke JW, Albers JJ.

Biochemistry. 2010 Aug 31;49(34):7314-22. doi: 10.1021/bi100359f.

40.

HDL lipids and insulin resistance.

Hoofnagle AN, Vaisar T, Mitra P, Chait A.

Curr Diab Rep. 2010 Feb;10(1):78-86. doi: 10.1007/s11892-009-0085-7. Review.

PMID:
20425071
41.

PepC: proteomics software for identifying differentially expressed proteins based on spectral counting.

Heinecke NL, Pratt BS, Vaisar T, Becker L.

Bioinformatics. 2010 Jun 15;26(12):1574-5. doi: 10.1093/bioinformatics/btq171. Epub 2010 Apr 22.

42.

HDL in humans with cardiovascular disease exhibits a proteomic signature.

Vaisar T, Mayer P, Nilsson E, Zhao XQ, Knopp R, Prazen BJ.

Clin Chim Acta. 2010 Jul 4;411(13-14):972-9. doi: 10.1016/j.cca.2010.03.023. Epub 2010 Mar 20.

43.

A macrophage sterol-responsive network linked to atherogenesis.

Becker L, Gharib SA, Irwin AD, Wijsman E, Vaisar T, Oram JF, Heinecke JW.

Cell Metab. 2010 Feb 3;11(2):125-35. doi: 10.1016/j.cmet.2010.01.003.

44.

An apoA-I mimetic peptide containing a proline residue has greater in vivo HDL binding and anti-inflammatory ability than the 4F peptide.

Wool GD, Vaisar T, Reardon CA, Getz GS.

J Lipid Res. 2009 Sep;50(9):1889-900. doi: 10.1194/jlr.M900151-JLR200. Epub 2009 May 11.

45.

Mapping the lung proteome in cystic fibrosis.

Gharib SA, Vaisar T, Aitken ML, Park DR, Heinecke JW, Fu X.

J Proteome Res. 2009 Jun;8(6):3020-8. doi: 10.1021/pr900093j.

PMID:
19354268
46.

Serum amyloid A3 does not contribute to circulating SAA levels.

Chiba T, Han CY, Vaisar T, Shimokado K, Kargi A, Chen MH, Wang S, McDonald TO, O'Brien KD, Heinecke JW, Chait A.

J Lipid Res. 2009 Jul;50(7):1353-62. doi: 10.1194/jlr.M900089-JLR200. Epub 2009 Mar 12.

47.

Thematic review series: proteomics. Proteomic analysis of lipid-protein complexes.

Vaisar T.

J Lipid Res. 2009 May;50(5):781-6. doi: 10.1194/jlr.R900005-JLR200. Epub 2009 Feb 19. Review.

48.

MMP-9 sheds the beta2 integrin subunit (CD18) from macrophages.

Vaisar T, Kassim SY, Gomez IG, Green PS, Hargarten S, Gough PJ, Parks WC, Wilson CL, Raines EW, Heinecke JW.

Mol Cell Proteomics. 2009 May;8(5):1044-60. doi: 10.1074/mcp.M800449-MCP200. Epub 2008 Dec 30.

49.

Combined statin and niacin therapy remodels the high-density lipoprotein proteome.

Green PS, Vaisar T, Pennathur S, Kulstad JJ, Moore AB, Marcovina S, Brunzell J, Knopp RH, Zhao XQ, Heinecke JW.

Circulation. 2008 Sep 16;118(12):1259-67. doi: 10.1161/CIRCULATIONAHA.108.770669. Epub 2008 Sep 2.

50.

Proteomic and computational analysis of bronchoalveolar proteins during the course of the acute respiratory distress syndrome.

Chang DW, Hayashi S, Gharib SA, Vaisar T, King ST, Tsuchiya M, Ruzinski JT, Park DR, Matute-Bello G, Wurfel MM, Bumgarner R, Heinecke JW, Martin TR.

Am J Respir Crit Care Med. 2008 Oct 1;178(7):701-9. doi: 10.1164/rccm.200712-1895OC. Epub 2008 Jul 24.

Supplemental Content

Loading ...
Support Center