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Items: 1 to 50 of 67

1.

MFF REGULATION OF MITOCHONDRIAL CELL DEATH IS A THERAPEUTIC TARGET IN CANCER.

Seo JH, Chae YC, Kossenkov AV, Lee YG, Tang HY, Agarwal E, Gabrilovich DI, Languino LR, Speicher DW, Shastrula PK, Storaci AM, Ferrero S, Gaudioso G, Caroli M, Tosi D, Giroda M, Vaira V, Rebecca VW, Herlyn M, Xiao M, Fingerman D, Martorella A, Skordalakes E, Altieri DC.

Cancer Res. 2019 Oct 3. pii: canres.1982.2019. doi: 10.1158/0008-5472.CAN-19-1982. [Epub ahead of print]

PMID:
31582380
2.

Mitochondrial fission factor is a novel Myc-dependent regulator of mitochondrial permeability in cancer.

Seo JH, Agarwal E, Chae YC, Lee YG, Garlick DS, Storaci AM, Ferrero S, Gaudioso G, Gianelli U, Vaira V, Altieri DC.

EBioMedicine. 2019 Oct;48:353-363. doi: 10.1016/j.ebiom.2019.09.017. Epub 2019 Sep 18.

3.

A miRNome analysis of drug-free manic psychotic bipolar patients versus healthy controls.

Tabano S, Caldiroli A, Terrasi A, Colapietro P, Grassi S, Carnevali GS, Fontana L, Serati M, Vaira V, Altamura AC, Miozzo M, Buoli M.

Eur Arch Psychiatry Clin Neurosci. 2019 Aug 17. doi: 10.1007/s00406-019-01057-2. [Epub ahead of print]

PMID:
31422452
4.

Mismatch Repair Protein Loss as a Prognostic and Predictive Biomarker in Breast Cancers Regardless of Microsatellite Instability.

Fusco N, Lopez G, Corti C, Pesenti C, Colapietro P, Ercoli G, Gaudioso G, Faversani A, Gambini D, Michelotti A, Despini L, Blundo C, Vaira V, Miozzo M, Ferrero S, Bosari S.

JNCI Cancer Spectr. 2018 Dec 13;2(4):pky056. doi: 10.1093/jncics/pky056. eCollection 2018 Oct.

5.

p65BTK is a novel potential actionable target in KRAS-mutated/EGFR-wild type lung adenocarcinoma.

Giordano F, Vaira V, Cortinovis D, Bonomo S, Goedmakers J, Brena F, Cialdella A, Ianzano L, Forno I, Cerrito MG, Giovannoni R, Ferri GL, Tasciotti E, Vicent S, Damarco F, Bosari S, Lavitrano M, Grassilli E.

J Exp Clin Cancer Res. 2019 Jun 14;38(1):260. doi: 10.1186/s13046-019-1199-7.

6.

Demystifying autoimmune small bowel enteropathy.

Elli L, Ferretti F, Vaira V.

Curr Opin Gastroenterol. 2019 May;35(3):243-249. doi: 10.1097/MOG.0000000000000515.

PMID:
30747741
7.

Specific V-ATPase expression sub-classifies IDHwt lower-grade gliomas and impacts glioma growth in vivo.

Terrasi A, Bertolini I, Martelli C, Gaudioso G, Di Cristofori A, Storaci AM, Formica M, Bosari S, Caroli M, Ottobrini L, Vaccari T, Vaira V.

EBioMedicine. 2019 Mar;41:214-224. doi: 10.1016/j.ebiom.2019.01.052. Epub 2019 Feb 5.

8.

A GBM-like V-ATPase signature directs cell-cell tumor signaling and reprogramming via large oncosomes.

Bertolini I, Terrasi A, Martelli C, Gaudioso G, Di Cristofori A, Storaci AM, Formica M, Braidotti P, Todoerti K, Ferrero S, Caroli M, Ottobrini L, Vaccari T, Vaira V.

EBioMedicine. 2019 Mar;41:225-235. doi: 10.1016/j.ebiom.2019.01.051. Epub 2019 Feb 6.

9.

Author Correction: MYC-driven epigenetic reprogramming favors the onset of tumorigenesis by inducing a stem cell-like state.

Poli V, Fagnocchi L, Fasciani A, Cherubini A, Mazzoleni S, Ferrillo S, Miluzio A, Gaudioso G, Vaira V, Turdo A, Gaggianesi M, Chinnici A, Lipari E, Bicciato S, Bosari S, Todaro M, Zippo A.

Nat Commun. 2018 Sep 20;9(1):3921. doi: 10.1038/s41467-018-06480-y.

10.

Gliadin effect on the oxidative balance and DNA damage: An in-vitro, ex-vivo study.

Monguzzi E, Marabini L, Elli L, Vaira V, Ferrero S, Ferretti F, Branchi F, Gaudioso G, Scricciolo A, Lombardo V, Doneda L, Roncoroni L.

Dig Liver Dis. 2019 Jan;51(1):47-54. doi: 10.1016/j.dld.2018.06.020. Epub 2018 Jul 3.

PMID:
30055963
11.

Transglutaminase 2 Mediates the Cytotoxicity of Resveratrol in a Human Cholangiocarcinoma and Gallbladder Cancer Cell Lines.

Roncoroni L, Elli L, Braidotti P, Tosi D, Vaira V, Tacchini L, Lombardo V, Branchi F, Scricciolo A, Doneda L.

Nutr Cancer. 2018 Jul;70(5):761-769. doi: 10.1080/01635581.2018.1470648. Epub 2018 May 14.

PMID:
29757003
12.

The aberrantly expressed miR-372 partly impairs sensitivity to apoptosis in parathyroid tumor cells.

Verdelli C, Forno I, Morotti A, Creo P, Guarnieri V, Scillitani A, Cetani F, Vicentini L, Balza G, Beretta E, Ferrero S, Vaira V, Corbetta S.

Endocr Relat Cancer. 2018 Jul;25(7):761-771. doi: 10.1530/ERC-17-0204. Epub 2018 May 3.

PMID:
29724878
13.

Expression of C19MC miRNAs in HCC associates with stem-cell features and the cancer-testis genes signature.

Augello C, Colombo F, Terrasi A, Trombetta E, Maggioni M, Porretti L, Rossi G, Guerneri S, Silipigni R, Bosari S, Vaira V.

Dig Liver Dis. 2018 Jun;50(6):583-593. doi: 10.1016/j.dld.2018.03.026. Epub 2018 Mar 30.

PMID:
29673952
14.

MYC-driven epigenetic reprogramming favors the onset of tumorigenesis by inducing a stem cell-like state.

Poli V, Fagnocchi L, Fasciani A, Cherubini A, Mazzoleni S, Ferrillo S, Miluzio A, Gaudioso G, Vaira V, Turdo A, Gaggianesi M, Chinnici A, Lipari E, Bicciato S, Bosari S, Todaro M, Zippo A.

Nat Commun. 2018 Mar 9;9(1):1024. doi: 10.1038/s41467-018-03264-2. Erratum in: Nat Commun. 2018 Sep 20;9(1):3921.

15.

Metformin and temozolomide, a synergic option to overcome resistance in glioblastoma multiforme models.

Valtorta S, Lo Dico A, Raccagni I, Gaglio D, Belloli S, Politi LS, Martelli C, Diceglie C, Bonanomi M, Ercoli G, Vaira V, Ottobrini L, Moresco RM.

Oncotarget. 2017 Dec 6;8(68):113090-113104. doi: 10.18632/oncotarget.23028. eCollection 2017 Dec 22.

16.

IMP3 expression in NSCLC brain metastases demonstrates its role as a prognostic factor in non-neuroendocrine phenotypes.

Del Gobbo A, Morotti A, Colombo AE, Vaira V, Ercoli G, Pesenti C, Bonaparte E, Guerini-Rocco E, Di Cristofori A, Locatelli M, Palleschi A, Ferrero S.

Med Oncol. 2017 Dec 1;35(1):2. doi: 10.1007/s12032-017-1062-7.

PMID:
29209838
17.

Expression, function, and regulation of the embryonic transcription factor TBX1 in parathyroid tumors.

Verdelli C, Avagliano L, Guarnieri V, Cetani F, Ferrero S, Vicentini L, Beretta E, Scillitani A, Creo P, Bulfamante GP, Vaira V, Corbetta S.

Lab Invest. 2017 Dec;97(12):1488-1499. doi: 10.1038/labinvest.2017.88. Epub 2017 Sep 18.

18.

Dopamine receptor type 2 (DRD2) and somatostatin receptor type 2 (SSTR2) agonists are effective in inhibiting proliferation of progenitor/stem-like cells isolated from nonfunctioning pituitary tumors.

Peverelli E, Giardino E, Treppiedi D, Meregalli M, Belicchi M, Vaira V, Corbetta S, Verdelli C, Verrua E, Serban AL, Locatelli M, Carrabba G, Gaudenzi G, Malchiodi E, Cassinelli L, Lania AG, Ferrero S, Bosari S, Vitale G, Torrente Y, Spada A, Mantovani G.

Int J Cancer. 2017 Apr 15;140(8):1870-1880. doi: 10.1002/ijc.30613. Epub 2017 Feb 8.

19.

Multicellular spheroids from normal and neoplastic thyroid tissues as a suitable model to test the effects of multikinase inhibitors.

Cirello V, Vaira V, Grassi ES, Vezzoli V, Ricca D, Colombo C, Bosari S, Vicentini L, Persani L, Ferrero S, Fugazzola L.

Oncotarget. 2017 Feb 7;8(6):9752-9766. doi: 10.18632/oncotarget.14187.

20.

A neuronal network of mitochondrial dynamics regulates metastasis.

Caino MC, Seo JH, Aguinaldo A, Wait E, Bryant KG, Kossenkov AV, Hayden JE, Vaira V, Morotti A, Ferrero S, Bosari S, Gabrilovich DI, Languino LR, Cohen AR, Altieri DC.

Nat Commun. 2016 Dec 19;7:13730. doi: 10.1038/ncomms13730.

21.

miR-494-3p is a novel tumor driver of lung carcinogenesis.

Faversani A, Amatori S, Augello C, Colombo F, Porretti L, Fanelli M, Ferrero S, Palleschi A, Pelicci PG, Belloni E, Ercoli G, Degrassi A, Baccarin M, Altieri DC, Vaira V, Bosari S.

Oncotarget. 2017 Jan 31;8(5):7231-7247. doi: 10.18632/oncotarget.13933.

22.

Filamin A is reduced and contributes to the CASR sensitivity in human parathyroid tumors.

Mingione A, Verdelli C, Ferrero S, Vaira V, Guarnieri V, Scillitani A, Vicentini L, Balza G, Beretta E, Terranegra A, Vezzoli G, Soldati L, Corbetta S.

J Mol Endocrinol. 2017 Feb;58(2):91-103. doi: 10.1530/JME-16-0184. Epub 2016 Nov 21.

23.

Transcriptional Landscape of Human Tissue Lymphocytes Unveils Uniqueness of Tumor-Infiltrating T Regulatory Cells.

De Simone M, Arrigoni A, Rossetti G, Gruarin P, Ranzani V, Politano C, Bonnal RJP, Provasi E, Sarnicola ML, Panzeri I, Moro M, Crosti M, Mazzara S, Vaira V, Bosari S, Palleschi A, Santambrogio L, Bovo G, Zucchini N, Totis M, Gianotti L, Cesana G, Perego RA, Maroni N, Pisani Ceretti A, Opocher E, De Francesco R, Geginat J, Stunnenberg HG, Abrignani S, Pagani M.

Immunity. 2016 Nov 15;45(5):1135-1147. doi: 10.1016/j.immuni.2016.10.021.

24.

MicroRNAs in parathyroid physiopathology.

Vaira V, Verdelli C, Forno I, Corbetta S.

Mol Cell Endocrinol. 2017 Nov 15;456:9-15. doi: 10.1016/j.mce.2016.10.035. Epub 2016 Nov 2. Review.

PMID:
27816765
25.

Dopamine receptor type 2 (DRD2) inhibits migration and invasion of human tumorous pituitary cells through ROCK-mediated cofilin inactivation.

Peverelli E, Giardino E, Treppiedi D, Locatelli M, Vaira V, Ferrero S, Bosari S, Lania AG, Spada A, Mantovani G.

Cancer Lett. 2016 Oct 28;381(2):279-86. doi: 10.1016/j.canlet.2016.08.005. Epub 2016 Aug 9.

PMID:
27519461
26.

Mitochondrial Akt Regulation of Hypoxic Tumor Reprogramming.

Chae YC, Vaira V, Caino MC, Tang HY, Seo JH, Kossenkov AV, Ottobrini L, Martelli C, Lucignani G, Bertolini I, Locatelli M, Bryant KG, Ghosh JC, Lisanti S, Ku B, Bosari S, Languino LR, Speicher DW, Altieri DC.

Cancer Cell. 2016 Aug 8;30(2):257-272. doi: 10.1016/j.ccell.2016.07.004.

27.

The Mitochondrial Unfoldase-Peptidase Complex ClpXP Controls Bioenergetics Stress and Metastasis.

Seo JH, Rivadeneira DB, Caino MC, Chae YC, Speicher DW, Tang HY, Vaira V, Bosari S, Palleschi A, Rampini P, Kossenkov AV, Languino LR, Altieri DC.

PLoS Biol. 2016 Jul 7;14(7):e1002507. doi: 10.1371/journal.pbio.1002507. eCollection 2016 Jul.

28.

Role of Strain Rate in the Pathogenesis of Ventilator-Induced Lung Edema.

Protti A, Maraffi T, Milesi M, Votta E, Santini A, Pugni P, Andreis DT, Nicosia F, Zannin E, Gatti S, Vaira V, Ferrero S, Gattinoni L.

Crit Care Med. 2016 Sep;44(9):e838-45. doi: 10.1097/CCM.0000000000001718.

PMID:
27054894
29.

The Contrasting Role of p16Ink4A Patterns of Expression in Neuroendocrine and Non-Neuroendocrine Lung Tumors: A Comprehensive Analysis with Clinicopathologic and Molecular Correlations.

Fusco N, Guerini-Rocco E, Del Gobbo A, Franco R, Zito-Marino F, Vaira V, Bulfamante G, Ercoli G, Nosotti M, Palleschi A, Bosari S, Ferrero S.

PLoS One. 2015 Dec 16;10(12):e0144923. doi: 10.1371/journal.pone.0144923. eCollection 2015.

30.

Analysis of NSCLC tumour heterogeneity, proliferative and 18F-FDG PET indices reveals Ki67 prognostic role in adenocarcinomas.

Del Gobbo A, Pellegrinelli A, Gaudioso G, Castellani M, Zito Marino F, Franco R, Palleschi A, Nosotti M, Bosari S, Vaira V, Ferrero S.

Histopathology. 2016 Apr;68(5):746-51. doi: 10.1111/his.12808. Epub 2015 Oct 23.

PMID:
26272457
31.

PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion.

Caino MC, Ghosh JC, Chae YC, Vaira V, Rivadeneira DB, Faversani A, Rampini P, Kossenkov AV, Aird KM, Zhang R, Webster MR, Weeraratna AT, Bosari S, Languino LR, Altieri DC.

Proc Natl Acad Sci U S A. 2015 Jul 14;112(28):8638-43. doi: 10.1073/pnas.1500722112. Epub 2015 Jun 29.

32.

Deregulation of MiR-34b/Sox2 Predicts Prostate Cancer Progression.

Forno I, Ferrero S, Russo MV, Gazzano G, Giangiobbe S, Montanari E, Del Nero A, Rocco B, Albo G, Languino LR, Altieri DC, Vaira V, Bosari S.

PLoS One. 2015 Jun 24;10(6):e0130060. doi: 10.1371/journal.pone.0130060. eCollection 2015.

33.

The vacuolar H+ ATPase is a novel therapeutic target for glioblastoma.

Di Cristofori A, Ferrero S, Bertolini I, Gaudioso G, Russo MV, Berno V, Vanini M, Locatelli M, Zavanone M, Rampini P, Vaccari T, Caroli M, Vaira V.

Oncotarget. 2015 Jul 10;6(19):17514-31.

34.

Identification of imaging biomarkers for the assessment of tumour response to different treatments in a preclinical glioma model.

Lo Dico A, Martelli C, Valtorta S, Raccagni I, Diceglie C, Belloli S, Gianelli U, Vaira V, Politi LS, Bosari S, Lucignani G, Moresco RM, Ottobrini L.

Eur J Nucl Med Mol Imaging. 2015 Jun;42(7):1093-105. doi: 10.1007/s00259-015-3040-7. Epub 2015 Mar 27.

PMID:
25813354
35.

A new mouse avatar model of non-small cell lung cancer.

Russo MV, Faversani A, Gatti S, Ricca D, Del Gobbo A, Ferrero S, Palleschi A, Vaira V, Bosari S.

Front Oncol. 2015 Mar 3;5:52. doi: 10.3389/fonc.2015.00052. eCollection 2015.

36.

Epigenetic alterations in human parathyroid tumors.

Verdelli C, Forno I, Vaira V, Corbetta S.

Endocrine. 2015 Jun;49(2):324-32. doi: 10.1007/s12020-015-0555-4. Epub 2015 Feb 27. Review.

PMID:
25722013
37.

The oncofetal protein IMP3: a novel grading tool and predictor of poor clinical outcome in human gliomas.

Del Gobbo A, Vaira V, Ferrari L, Patriarca C, Di Cristofori A, Ricca D, Caroli M, Rampini P, Bosari S, Ferrero S.

Biomed Res Int. 2015;2015:413897. doi: 10.1155/2015/413897. Epub 2015 Jan 28.

38.

Adaptive mitochondrial reprogramming and resistance to PI3K therapy.

Ghosh JC, Siegelin MD, Vaira V, Faversani A, Tavecchio M, Chae YC, Lisanti S, Rampini P, Giroda M, Caino MC, Seo JH, Kossenkov AV, Michalek RD, Schultz DC, Bosari S, Languino LR, Altieri DC.

J Natl Cancer Inst. 2015 Feb 3;107(3). pii: dju502. doi: 10.1093/jnci/dju502. Print 2015 Mar.

39.

Epigenetic alterations in cancer and personalized cancer treatment.

Miozzo M, Vaira V, Sirchia SM.

Future Oncol. 2015;11(2):333-48. doi: 10.2217/fon.14.237. Review.

PMID:
25591842
40.

MicroRNA deregulation in parathyroid tumours suggests an embryonic signature.

Verdelli C, Forno I, Vaira V, Corbetta S.

J Endocrinol Invest. 2015 Apr;38(4):383-8. doi: 10.1007/s40618-014-0234-y. Epub 2015 Jan 11. Review.

PMID:
25577262
41.

Interferon lambda-3 is not associated with clinical outcome in patients with HCV-induced compensated cirrhosis: a long-term cohort study.

Bruno S, Thompson AJ, Critelli R, Crosignani A, Rossi S, De Lisi S, Cariani E, Zermiani P, Vaira V, Boccaccio V, Maisonneuve P, Villa E.

Antiviral Res. 2015 Jan;113:27-32. doi: 10.1016/j.antiviral.2014.11.002. Epub 2014 Nov 11.

PMID:
25446338
42.

Different expression of protein kinase A (PKA) regulatory subunits in normal and neoplastic thyroid tissues.

Ferrero S, Vaira V, Del Gobbo A, Vicentini L, Bosari S, Beck-Peccoz P, Mantovani G, Spada A, Lania AG.

Histol Histopathol. 2015 Apr;30(4):473-8. doi: 10.14670/HH-30.473. Epub 2014 Sep 26.

43.

The oncofetal protein IMP3: a useful marker to predict poor clinical outcome in neuroendocrine tumors of the lung.

Del Gobbo A, Vaira V, Guerini Rocco E, Palleschi A, Bulfamante G, Ricca D, Fiori S, Bosari S, Ferrero S.

J Thorac Oncol. 2014 Nov;9(11):1656-61. doi: 10.1097/JTO.0000000000000316.

44.

MicroRNA-425-3p predicts response to sorafenib therapy in patients with hepatocellular carcinoma.

Vaira V, Roncalli M, Carnaghi C, Faversani A, Maggioni M, Augello C, Rimassa L, Pressiani T, Spagnuolo G, Di Tommaso L, Fagiuoli S, Rota Caremoli E, Barberis M, Labianca R, Santoro A, Bosari S.

Liver Int. 2015 Mar;35(3):1077-86. doi: 10.1111/liv.12636. Epub 2014 Jul 21.

PMID:
25040368
45.

MicroRNA as potential biomarker in HCV-associated diffuse large B-cell lymphoma.

Augello C, Gianelli U, Savi F, Moro A, Bonoldi E, Gambacorta M, Vaira V, Baldini L, Bosari S.

J Clin Pathol. 2014 Aug;67(8):697-701. doi: 10.1136/jclinpath-2014-202352. Epub 2014 Jun 9.

PMID:
24914240
46.

Survivin family proteins as novel molecular determinants of doxorubicin resistance in organotypic human breast tumors.

Faversani A, Vaira V, Moro GP, Tosi D, Lopergolo A, Schultz DC, Rivadeneira D, Altieri DC, Bosari S.

Breast Cancer Res. 2014 May 30;16(3):R55. doi: 10.1186/bcr3666.

47.

miR-296/Scribble axis is deregulated in human breast cancer and miR-296 restoration reduces tumour growth in vivo.

Savi F, Forno I, Faversani A, Luciani A, Caldiera S, Gatti S, Foa P, Ricca D, Bulfamante G, Vaira V, Bosari S.

Clin Sci (Lond). 2014 Aug;127(4):233-42. doi: 10.1042/CS20130580.

PMID:
24527800
48.

microRNA profiles in coeliac patients distinguish different clinical phenotypes and are modulated by gliadin peptides in primary duodenal fibroblasts.

Vaira V, Roncoroni L, Barisani D, Gaudioso G, Bosari S, Bulfamante G, Doneda L, Conte D, Tomba C, Bardella MT, Ferrero S, Locatelli M, Elli L.

Clin Sci (Lond). 2014 Mar;126(6):417-23. doi: 10.1042/CS20130248.

PMID:
24063611
49.

Metabolic stress regulates cytoskeletal dynamics and metastasis of cancer cells.

Caino MC, Chae YC, Vaira V, Ferrero S, Nosotti M, Martin NM, Weeraratna A, O'Connell M, Jernigan D, Fatatis A, Languino LR, Bosari S, Altieri DC.

J Clin Invest. 2013 Jul;123(7):2907-20. doi: 10.1172/JCI67841. Epub 2013 Jun 10.

50.

Regulation of lung cancer metastasis by Klf4-Numb-like signaling.

Vaira V, Faversani A, Martin NM, Garlick DS, Ferrero S, Nosotti M, Kissil JL, Bosari S, Altieri DC.

Cancer Res. 2013 Apr 15;73(8):2695-705. doi: 10.1158/0008-5472.CAN-12-4232. Epub 2013 Feb 25.

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