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Items: 37

1.

Self-assembled nanofibrils from RGD-functionalized cellulose nanocrystals to improve the performance of PEI/DNA polyplexes.

Hujaya SD, Manninen A, Kling K, Wagner JB, Vainio SJ, Liimatainen H.

J Colloid Interface Sci. 2019 Oct 1;553:71-82. doi: 10.1016/j.jcis.2019.06.001. Epub 2019 Jun 3.

PMID:
31200231
2.

Embryonic Stem Cells Derived Kidney Organoids as Faithful Models to Target Programmed Nephrogenesis.

Tan Z, Shan J, Rak-Raszewska A, Vainio SJ.

Sci Rep. 2018 Nov 9;8(1):16618. doi: 10.1038/s41598-018-34995-3.

3.

Polyion complex hydrogels from chemically modified cellulose nanofibrils: Structure-function relationship and potential for controlled and pH-responsive release of doxorubicin.

Hujaya SD, Lorite GS, Vainio SJ, Liimatainen H.

Acta Biomater. 2018 Jul 15;75:346-357. doi: 10.1016/j.actbio.2018.06.013. Epub 2018 Jun 7.

PMID:
29885527
4.

Exosomes as secondary inductive signals involved in kidney organogenesis.

Krause M, Rak-Raszewska A, Naillat F, Saarela U, Schmidt C, Ronkainen VP, Bart G, Ylä-Herttuala S, Vainio SJ.

J Extracell Vesicles. 2018 Jan 23;7(1):1422675. doi: 10.1080/20013078.2017.1422675. eCollection 2018.

5.

HNF1B controls epithelial organization and cell polarity during ureteric bud branching and collecting duct morphogenesis.

Desgrange A, Heliot C, Skovorodkin I, Akram SU, Heikkilä J, Ronkainen VP, Miinalainen I, Vainio SJ, Cereghini S.

Development. 2017 Dec 15;144(24):4704-4719. doi: 10.1242/dev.154336. Epub 2017 Nov 20.

6.

Renal carcinoma/kidney progenitor cell chimera organoid as a novel tumorigenesis gene discovery model.

Xu Q, Junttila S, Scherer A, Giri KR, Kivelä O, Skovorodkin I, Röning J, Quaggin SE, Marti HP, Shan J, Samoylenko A, Vainio SJ.

Dis Model Mech. 2017 Dec 19;10(12):1503-1515. doi: 10.1242/dmm.028332.

7.

Editorial: Organogenesis: From Development to Disease.

Sims-Lucas S, Good M, Vainio SJ.

Front Cell Dev Biol. 2017 Sep 20;5:85. doi: 10.3389/fcell.2017.00085. eCollection 2017. No abstract available.

8.

Kidney development and perspectives for organ engineering.

Reint G, Rak-Raszewska A, Vainio SJ.

Cell Tissue Res. 2017 Jul;369(1):171-183. doi: 10.1007/s00441-017-2616-x. Epub 2017 Apr 20. Review.

PMID:
28429072
9.

BMP7 Induces Uterine Receptivity and Blastocyst Attachment.

Monsivais D, Clementi C, Peng J, Fullerton PT Jr, Prunskaite-Hyyryläinen R, Vainio SJ, Matzuk MM.

Endocrinology. 2017 Apr 1;158(4):979-992. doi: 10.1210/en.2016-1629.

10.

The CapZ interacting protein Rcsd1 is required for cardiogenesis downstream of Wnt11a in Xenopus laevis.

Hempel A, Kühl SJ, Rothe M, Rao Tata P, Sirbu IO, Vainio SJ, Kühl M.

Dev Biol. 2017 Apr 1;424(1):28-39. doi: 10.1016/j.ydbio.2017.02.014. Epub 2017 Feb 22.

11.

Novel fixed z-direction (FiZD) kidney primordia and an organoid culture system for time-lapse confocal imaging.

Saarela U, Akram SU, Desgrange A, Rak-Raszewska A, Shan J, Cereghini S, Ronkainen VP, Heikkilä J, Skovorodkin I, Vainio SJ.

Development. 2017 Mar 15;144(6):1113-1117. doi: 10.1242/dev.142950. Epub 2017 Feb 20.

12.

Impairment of Wnt11 function leads to kidney tubular abnormalities and secondary glomerular cystogenesis.

Nagy II, Xu Q, Naillat F, Ali N, Miinalainen I, Samoylenko A, Vainio SJ.

BMC Dev Biol. 2016 Aug 31;16(1):30. doi: 10.1186/s12861-016-0131-z.

13.

CD146(+) cells are essential for kidney vasculature development.

Halt KJ, Pärssinen HE, Junttila SM, Saarela U, Sims-Lucas S, Koivunen P, Myllyharju J, Quaggin S, Skovorodkin IN, Vainio SJ.

Kidney Int. 2016 Aug;90(2):311-324. doi: 10.1016/j.kint.2016.02.021. Epub 2016 Apr 18.

14.

Wnt5a Deficiency Leads to Anomalies in Ureteric Tree Development, Tubular Epithelial Cell Organization and Basement Membrane Integrity Pointing to a Role in Kidney Collecting Duct Patterning.

Pietilä I, Prunskaite-Hyyryläinen R, Kaisto S, Tika E, van Eerde AM, Salo AM, Garma L, Miinalainen I, Feitz WF, Bongers EM, Juffer A, Knoers NV, Renkema KY, Myllyharju J, Vainio SJ.

PLoS One. 2016 Jan 21;11(1):e0147171. doi: 10.1371/journal.pone.0147171. eCollection 2016.

15.

Wnt4 coordinates directional cell migration and extension of the Müllerian duct essential for ontogenesis of the female reproductive tract.

Prunskaite-Hyyryläinen R, Skovorodkin I, Xu Q, Miinalainen I, Shan J, Vainio SJ.

Hum Mol Genet. 2016 Mar 15;25(6):1059-73. doi: 10.1093/hmg/ddv621. Epub 2015 Dec 31.

16.

Exosomes as renal inductive signals in health and disease, and their application as diagnostic markers and therapeutic agents.

Krause M, Samoylenko A, Vainio SJ.

Front Cell Dev Biol. 2015 Oct 20;3:65. doi: 10.3389/fcell.2015.00065. eCollection 2015. Review.

17.

ATGme: Open-source web application for rare codon identification and custom DNA sequence optimization.

Daniel E, Onwukwe GU, Wierenga RK, Quaggin SE, Vainio SJ, Krause M.

BMC Bioinformatics. 2015 Sep 21;16:303. doi: 10.1186/s12859-015-0743-5.

18.

Identification of the genes regulated by Wnt-4, a critical signal for commitment of the ovary.

Naillat F, Yan W, Karjalainen R, Liakhovitskaia A, Samoylenko A, Xu Q, Sun Z, Shen B, Medvinsky A, Quaggin S, Vainio SJ.

Exp Cell Res. 2015 Mar 15;332(2):163-78. doi: 10.1016/j.yexcr.2015.01.010. Epub 2015 Jan 30.

19.

Progesterone and Wnt4 control mammary stem cells via myoepithelial crosstalk.

Rajaram RD, Buric D, Caikovski M, Ayyanan A, Rougemont J, Shan J, Vainio SJ, Yalcin-Ozuysal O, Brisken C.

EMBO J. 2015 Mar 4;34(5):641-52. doi: 10.15252/embj.201490434. Epub 2015 Jan 20.

20.

Functional genetic targeting of embryonic kidney progenitor cells ex vivo.

Junttila S, Saarela U, Halt K, Manninen A, Pärssinen H, Lecca MR, Brändli AW, Sims-Lucas S, Skovorodkin I, Vainio SJ.

J Am Soc Nephrol. 2015 May;26(5):1126-37. doi: 10.1681/ASN.2013060584. Epub 2014 Sep 8.

21.

ErbB4, a receptor tyrosine kinase, coordinates organization of the seminiferous tubules in the developing testis.

Naillat F, Veikkolainen V, Miinalainen I, Sipilä P, Poutanen M, Elenius K, Vainio SJ.

Mol Endocrinol. 2014 Sep;28(9):1534-46. doi: 10.1210/me.2013-1244. Epub 2014 Jul 24.

22.

Loss of the podocyte-expressed transcription factor Tcf21/Pod1 results in podocyte differentiation defects and FSGS.

Maezawa Y, Onay T, Scott RP, Keir LS, Dimke H, Li C, Eremina V, Maezawa Y, Jeansson M, Shan J, Binnie M, Lewin M, Ghosh A, Miner JH, Vainio SJ, Quaggin SE.

J Am Soc Nephrol. 2014 Nov;25(11):2459-70. doi: 10.1681/ASN.2013121307. Epub 2014 Jun 5.

23.

Kidney development: an overview.

Pietilä I, Vainio SJ.

Nephron Exp Nephrol. 2014;126(2):40. doi: 10.1159/000360659. Epub 2014 May 19. Review.

24.

Wnt4, a pleiotropic signal for controlling cell polarity, basement membrane integrity, and antimüllerian hormone expression during oocyte maturation in the female follicle.

Prunskaite-Hyyryläinen R, Shan J, Railo A, Heinonen KM, Miinalainen I, Yan W, Shen B, Perreault C, Vainio SJ.

FASEB J. 2014 Apr;28(4):1568-81. doi: 10.1096/fj.13-233247. Epub 2013 Dec 26.

PMID:
24371124
25.

Improving signal detection in emission optical projection tomography via single source multi-exposure image fusion.

Cheddad A, Nord C, Hörnblad A, Prunskaite-Hyyryläinen R, Eriksson M, Georgsson F, Vainio SJ, Ahlgren U.

Opt Express. 2013 Jul 15;21(14):16584-604. doi: 10.1364/OE.21.016584.

PMID:
23938510
26.

Wnt5a cooperates with canonical Wnts to generate midbrain dopaminergic neurons in vivo and in stem cells.

Andersson ER, Saltó C, Villaescusa JC, Cajanek L, Yang S, Bryjova L, Nagy II, Vainio SJ, Ramirez C, Bryja V, Arenas E.

Proc Natl Acad Sci U S A. 2013 Feb 12;110(7):E602-10. doi: 10.1073/pnas.1208524110. Epub 2013 Jan 16.

27.

Conditional expression of Lodavin, an avidin-tagged LDL receptor, for biotin-mediated applications in vivo.

Murugan S, Saarela U, Airenne K, Shan J, Skovorodkin I, Ylä-Herttuala S, Vainio SJ.

Genesis. 2012 Sep;50(9):693-9. doi: 10.1002/dvg.22028. Epub 2012 Apr 24.

PMID:
22467513
28.

WT1 and Sox11 regulate synergistically the promoter of the Wnt4 gene that encodes a critical signal for nephrogenesis.

Murugan S, Shan J, Kühl SJ, Tata A, Pietilä I, Kühl M, Vainio SJ.

Exp Cell Res. 2012 Jun 10;318(10):1134-45. doi: 10.1016/j.yexcr.2012.03.008. Epub 2012 Mar 17.

PMID:
22465478
29.

A secreted BMP antagonist, Cer1, fine tunes the spatial organization of the ureteric bud tree during mouse kidney development.

Chi L, Saarela U, Railo A, Prunskaite-Hyyryläinen R, Skovorodkin I, Anthony S, Katsu K, Liu Y, Shan J, Salgueiro AM, Belo JA, Davies J, Yokouchi Y, Vainio SJ.

PLoS One. 2011;6(11):e27676. doi: 10.1371/journal.pone.0027676. Epub 2011 Nov 17.

30.

Wnt4 regulates thymic cellularity through the expansion of thymic epithelial cells and early thymic progenitors.

Heinonen KM, Vanegas JR, Brochu S, Shan J, Vainio SJ, Perreault C.

Blood. 2011 Nov 10;118(19):5163-73. doi: 10.1182/blood-2011-04-350553. Epub 2011 Sep 21.

PMID:
21937690
31.

Secreted Wnt antagonist Dickkopf-1 controls kidney papilla development coordinated by Wnt-7b signalling.

Pietilä I, Ellwanger K, Railo A, Jokela T, Barrantes Idel B, Shan J, Niehrs C, Vainio SJ.

Dev Biol. 2011 May 1;353(1):50-60. doi: 10.1016/j.ydbio.2011.02.019. Epub 2011 Feb 24.

32.

Wnt4/5a signalling coordinates cell adhesion and entry into meiosis during presumptive ovarian follicle development.

Naillat F, Prunskaite-Hyyryläinen R, Pietilä I, Sormunen R, Jokela T, Shan J, Vainio SJ.

Hum Mol Genet. 2010 Apr 15;19(8):1539-50. doi: 10.1093/hmg/ddq027. Epub 2010 Jan 27.

PMID:
20106871
33.

Wnt-11 signalling controls ventricular myocardium development by patterning N-cadherin and beta-catenin expression.

Nagy II, Railo A, Rapila R, Hast T, Sormunen R, Tavi P, Räsänen J, Vainio SJ.

Cardiovasc Res. 2010 Jan 1;85(1):100-9. doi: 10.1093/cvr/cvp254.

PMID:
19622544
34.

A mouse model for alpha-methylacyl-CoA racemase deficiency: adjustment of bile acid synthesis and intolerance to dietary methyl-branched lipids.

Savolainen K, Kotti TJ, Schmitz W, Savolainen TI, Sormunen RT, Ilves M, Vainio SJ, Conzelmann E, Hiltunen JK.

Hum Mol Genet. 2004 May 1;13(9):955-65. Epub 2004 Mar 11.

PMID:
15016763
35.

Nephrogenesis regulated by Wnt signaling.

Vainio SJ.

J Nephrol. 2003 Mar-Apr;16(2):279-85. Review.

PMID:
12768078
36.

A road to kidney tubules via the Wnt pathway.

Vainio SJ, Uusitalo MS.

Pediatr Nephrol. 2000 Nov;15(1-2):151-6. Review.

PMID:
11095034
37.

Wnts as kidney tubule inducing factors.

Vainio SJ, Itäranta PV, Peräsaari JP, Uusitalo MS.

Int J Dev Biol. 1999;43(5):419-23. Review.

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