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Items: 1 to 50 of 57

1.

Biomarker-guided antifungal stewardship policies for patients with invasive candidiasis.

Honarvar B, Bagheri Lankarani K, Taghavi M, Vahedi G, Mortaz E.

Curr Med Mycol. 2018 Dec;4(4):37-44. doi: 10.18502/cmm.4.4.385. Review.

2.

Oncogenic Notch Promotes Long-Range Regulatory Interactions within Hyperconnected 3D Cliques.

Petrovic J, Zhou Y, Fasolino M, Goldman N, Schwartz GW, Mumbach MR, Nguyen SC, Rome KS, Sela Y, Zapataro Z, Blacklow SC, Kruhlak MJ, Shi J, Aster JC, Joyce EF, Little SC, Vahedi G, Pear WS, Faryabi RB.

Mol Cell. 2019 Mar 21;73(6):1174-1190.e12. doi: 10.1016/j.molcel.2019.01.006. Epub 2019 Feb 7.

PMID:
30745086
3.

Epigenetic mechanisms are behind the regulation of the key genes associated with the osteoblastic differentiation of the mesenchymal stem cells: The role of zoledronic acid on tuning the epigenetic changes.

Marofi F, Hassanzadeh A, Solali S, Vahedi G, Mousavi Ardehaie R, Salarinasab S, Aliparasti MR, Ghaebi M, Farshdousti Hagh M.

J Cell Physiol. 2019 Jan 16. doi: 10.1002/jcp.28152. [Epub ahead of print]

PMID:
30652308
4.

Gene expression of TWIST1 and ZBTB16 is regulated by methylation modifications during the osteoblastic differentiation of mesenchymal stem cells.

Marofi F, Vahedi G, Solali S, Alivand M, Salarinasab S, Zadi Heydarabad M, Farshdousti Hagh M.

J Cell Physiol. 2019 May;234(5):6230-6243. doi: 10.1002/jcp.27352. Epub 2018 Sep 24.

PMID:
30246336
5.

Mesenchymal stem cells as the game-changing tools in the treatment of various organs disorders: Mirage or reality?

Marofi F, Vahedi G, Hasanzadeh A, Salarinasab S, Arzhanga P, Khademi B, Farshdousti Hagh M.

J Cell Physiol. 2019 Feb;234(2):1268-1288. doi: 10.1002/jcp.27152. Epub 2018 Sep 7. Review.

PMID:
30191962
6.

A Cosine Similarity-Based Method to Infer Variability of Chromatin Accessibility at the Single-Cell Level.

Cai S, Georgakilas GK, Johnson JL, Vahedi G.

Front Genet. 2018 Aug 15;9:319. doi: 10.3389/fgene.2018.00319. eCollection 2018.

7.

Identification and characterization of HIV-specific resident memory CD8+ T cells in human lymphoid tissue.

Buggert M, Nguyen S, Salgado-Montes de Oca G, Bengsch B, Darko S, Ransier A, Roberts ER, Del Alcazar D, Brody IB, Vella LA, Beura L, Wijeyesinghe S, Herati RS, Del Rio Estrada PM, Ablanedo-Terrazas Y, Kuri-Cervantes L, Sada Japp A, Manne S, Vartanian S, Huffman A, Sandberg JK, Gostick E, Nadolski G, Silvestri G, Canaday DH, Price DA, Petrovas C, Su LF, Vahedi G, Dori Y, Frank I, Itkin MG, Wherry EJ, Deeks SG, Naji A, Reyes-Terán G, Masopust D, Douek DC, Betts MR.

Sci Immunol. 2018 Jun 1;3(24). pii: eaar4526. doi: 10.1126/sciimmunol.aar4526.

8.

Long genes linked to autism spectrum disorders harbor broad enhancer-like chromatin domains.

Zhao YT, Kwon DY, Johnson BS, Fasolino M, Lamonica JM, Kim YJ, Zhao BS, He C, Vahedi G, Kim TH, Zhou Z.

Genome Res. 2018 Jul;28(7):933-942. doi: 10.1101/gr.233775.117. Epub 2018 May 30.

9.

Zymosan attenuates melanoma growth progression, increases splenocyte proliferation and induces TLR-2/4 and TNF-α expression in mice.

Taghavi M, Mortaz E, Khosravi A, Vahedi G, Folkerts G, Varahram M, Kazempour-Dizaji M, Garssen J, Adcock IM.

J Inflamm (Lond). 2018 Mar 22;15:5. doi: 10.1186/s12950-018-0182-y. eCollection 2018.

10.

Chronic mucocutaneous candidiasis, a case study and literature review.

Khosravi AR, Mansouri P, Saffarian Z, Vahedi G, Nikaein D.

J Mycol Med. 2018 Mar;28(1):206-210. doi: 10.1016/j.mycmed.2018.02.004. Epub 2018 Feb 28. Review.

PMID:
29500032
11.

Lineage-Determining Transcription Factor TCF-1 Initiates the Epigenetic Identity of T Cells.

Johnson JL, Georgakilas G, Petrovic J, Kurachi M, Cai S, Harly C, Pear WS, Bhandoola A, Wherry EJ, Vahedi G.

Immunity. 2018 Feb 20;48(2):243-257.e10. doi: 10.1016/j.immuni.2018.01.012.

12.

Mesenchymal Stromal/Stem Cells: A New Era in the Cell-Based Targeted Gene Therapy of Cancer.

Marofi F, Vahedi G, Biglari A, Esmaeilzadeh A, Athari SS.

Front Immunol. 2017 Dec 18;8:1770. doi: 10.3389/fimmu.2017.01770. eCollection 2017. Review.

13.

Biotin tagging of MeCP2 in mice reveals contextual insights into the Rett syndrome transcriptome.

Johnson BS, Zhao YT, Fasolino M, Lamonica JM, Kim YJ, Georgakilas G, Wood KH, Bu D, Cui Y, Goffin D, Vahedi G, Kim TH, Zhou Z.

Nat Med. 2017 Oct;23(10):1203-1214. doi: 10.1038/nm.4406. Epub 2017 Sep 18.

14.

GR Extinguishes Inflamed Chromatin, and NF-κB Evacuates.

Fasolino M, Vahedi G.

Immunity. 2017 Aug 15;47(2):214-216. doi: 10.1016/j.immuni.2017.07.025.

15.

IL-10 induces a STAT3-dependent autoregulatory loop in TH2 cells that promotes Blimp-1 restriction of cell expansion via antagonism of STAT5 target genes.

Poholek AC, Jankovic D, Villarino AV, Petermann F, Hettinga A, Shouval DS, Snapper SB, Kaech SM, Brooks SR, Vahedi G, Sher A, Kanno Y, O'Shea JJ.

Sci Immunol. 2016 Oct;1(5). pii: eaaf8612. Epub 2016 Nov 11.

16.

Do Memory CD4 T Cells Keep Their Cell-Type Programming: Plasticity versus Fate Commitment? Epigenome: A Dynamic Vehicle for Transmitting and Recording Cytokine Signaling.

Johnson JL, Vahedi G.

Cold Spring Harb Perspect Biol. 2018 Mar 1;10(3). pii: a028779. doi: 10.1101/cshperspect.a028779. Review.

PMID:
28432132
17.

Presence and distribution of yeasts in the reproductive tract in healthy female horses.

Azarvandi A, Khosravi AR, Shokri H, Talebkhan Garoussi M, Gharahgouzlou F, Vahedi G, Sharifzadeh A.

Equine Vet J. 2017 Sep;49(5):614-617. doi: 10.1111/evj.12657. Epub 2017 Jan 22.

PMID:
27931081
18.

Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade.

Pauken KE, Sammons MA, Odorizzi PM, Manne S, Godec J, Khan O, Drake AM, Chen Z, Sen DR, Kurachi M, Barnitz RA, Bartman C, Bengsch B, Huang AC, Schenkel JM, Vahedi G, Haining WN, Berger SL, Wherry EJ.

Science. 2016 Dec 2;354(6316):1160-1165. Epub 2016 Oct 27.

19.

Targeted genomic analysis reveals widespread autoimmune disease association with regulatory variants in the TNF superfamily cytokine signalling network.

Richard AC, Peters JE, Lee JC, Vahedi G, Schäffer AA, Siegel RM, Lyons PA, Smith KG.

Genome Med. 2016 Jul 19;8(1):76. doi: 10.1186/s13073-016-0329-5.

20.

Exploiting Chromatin Biology to Understand Immunology.

Johnson JL, Vahedi G.

Methods Enzymol. 2016;574:365-383. doi: 10.1016/bs.mie.2016.03.016. Epub 2016 Apr 27.

PMID:
27423869
21.

A comparative study of the timecourse of the expression of the thermo‑inducible HSP70 gene in clinical and environmental isolates of Aspergillus fumigatus.

Sharafi G, Khosravi AR, Vahedi G, Yahyaraeyat R, Abbasi T.

Mol Med Rep. 2016 May;13(5):4513-21. doi: 10.3892/mmr.2016.5058. Epub 2016 Mar 28.

PMID:
27035559
22.

Factors in Etiology and Predisposition of Adult Tinea Capitis and Review of Published Literature.

Khosravi AR, Shokri H, Vahedi G.

Mycopathologia. 2016 Jun;181(5-6):371-8. doi: 10.1007/s11046-016-0004-9. Epub 2016 Mar 23. Review.

PMID:
27004946
23.

Interleukin-23-Induced Transcription Factor Blimp-1 Promotes Pathogenicity of T Helper 17 Cells.

Jain R, Chen Y, Kanno Y, Joyce-Shaikh B, Vahedi G, Hirahara K, Blumenschein WM, Sukumar S, Haines CJ, Sadekova S, McClanahan TK, McGeachy MJ, O'Shea JJ, Cua DJ.

Immunity. 2016 Jan 19;44(1):131-142. doi: 10.1016/j.immuni.2015.11.009. Epub 2015 Dec 29.

24.

Enhancing our understanding of enhancers in T-helper cells.

Paiano JJ, Johnson JL, Vahedi G.

Eur J Immunol. 2015 Nov;45(11):2998-3001. doi: 10.1002/eji.201546035. Epub 2015 Oct 20.

25.

Super-enhancers: Asset management in immune cell genomes.

Witte S, O'Shea JJ, Vahedi G.

Trends Immunol. 2015 Sep;36(9):519-26. doi: 10.1016/j.it.2015.07.005. Epub 2015 Aug 12. Review.

26.

EZH2 is crucial for both differentiation of regulatory T cells and T effector cell expansion.

Yang XP, Jiang K, Hirahara K, Vahedi G, Afzali B, Sciume G, Bonelli M, Sun HW, Jankovic D, Kanno Y, Sartorelli V, O'Shea JJ, Laurence A.

Sci Rep. 2015 Jun 19;5:10643. doi: 10.1038/srep10643.

27.

Asymmetric Action of STAT Transcription Factors Drives Transcriptional Outputs and Cytokine Specificity.

Hirahara K, Onodera A, Villarino AV, Bonelli M, Sciumè G, Laurence A, Sun HW, Brooks SR, Vahedi G, Shih HY, Gutierrez-Cruz G, Iwata S, Suzuki R, Mikami Y, Okamoto Y, Nakayama T, Holland SM, Hunter CA, Kanno Y, O'Shea JJ.

Immunity. 2015 May 19;42(5):877-89. doi: 10.1016/j.immuni.2015.04.014.

28.

Super-enhancers delineate disease-associated regulatory nodes in T cells.

Vahedi G, Kanno Y, Furumoto Y, Jiang K, Parker SC, Erdos MR, Davis SR, Roychoudhuri R, Restifo NP, Gadina M, Tang Z, Ruan Y, Collins FS, Sartorelli V, O'Shea JJ.

Nature. 2015 Apr 23;520(7548):558-62. doi: 10.1038/nature14154. Epub 2015 Feb 16.

29.

BRD4 assists elongation of both coding and enhancer RNAs by interacting with acetylated histones.

Kanno T, Kanno Y, LeRoy G, Campos E, Sun HW, Brooks SR, Vahedi G, Heightman TD, Garcia BA, Reinberg D, Siebenlist U, O'Shea JJ, Ozato K.

Nat Struct Mol Biol. 2014 Dec;21(12):1047-57. doi: 10.1038/nsmb.2912. Epub 2014 Nov 10.

30.

Transcriptional and epigenetic networks of helper T and innate lymphoid cells.

Shih HY, Sciumè G, Poholek AC, Vahedi G, Hirahara K, Villarino AV, Bonelli M, Bosselut R, Kanno Y, Muljo SA, O'Shea JJ.

Immunol Rev. 2014 Sep;261(1):23-49. doi: 10.1111/imr.12208. Review.

31.

Enhancing the understanding of asthma.

Vahedi G, Richard AC, O'Shea JJ.

Nat Immunol. 2014 Aug;15(8):701-3. doi: 10.1038/ni.2946. No abstract available.

32.

Helper T cell plasticity: impact of extrinsic and intrinsic signals on transcriptomes and epigenomes.

Bonelli M, Shih HY, Hirahara K, Singelton K, Laurence A, Poholek A, Hand T, Mikami Y, Vahedi G, Kanno Y, O'Shea JJ.

Curr Top Microbiol Immunol. 2014;381:279-326. doi: 10.1007/82_2014_371. Review.

33.

A mouse model of HIES reveals pro- and anti-inflammatory functions of STAT3.

Steward-Tharp SM, Laurence A, Kanno Y, Kotlyar A, Villarino AV, Sciume G, Kuchen S, Resch W, Wohlfert EA, Jiang K, Hirahara K, Vahedi G, Sun HW, Feigenbaum L, Milner JD, Holland SM, Casellas R, Powrie F, O'Shea JJ.

Blood. 2014 May 8;123(19):2978-87. doi: 10.1182/blood-2013-09-523167. Epub 2014 Mar 14.

34.

Type I IFN induces binding of STAT1 to Bcl6: divergent roles of STAT family transcription factors in the T follicular helper cell genetic program.

Nakayamada S, Poholek AC, Lu KT, Takahashi H, Kato M, Iwata S, Hirahara K, Cannons JL, Schwartzberg PL, Vahedi G, Sun HW, Kanno Y, O'Shea JJ.

J Immunol. 2014 Mar 1;192(5):2156-66. doi: 10.4049/jimmunol.1300675. Epub 2014 Jan 31.

35.

BACH2 represses effector programs to stabilize T(reg)-mediated immune homeostasis.

Roychoudhuri R, Hirahara K, Mousavi K, Clever D, Klebanoff CA, Bonelli M, Sciumè G, Zare H, Vahedi G, Dema B, Yu Z, Liu H, Takahashi H, Rao M, Muranski P, Crompton JG, Punkosdy G, Bedognetti D, Wang E, Hoffmann V, Rivera J, Marincola FM, Nakamura A, Sartorelli V, Kanno Y, Gattinoni L, Muto A, Igarashi K, O'Shea JJ, Restifo NP.

Nature. 2013 Jun 27;498(7455):506-10. doi: 10.1038/nature12199. Epub 2013 Jun 2.

36.

Mechanisms underlying helper T-cell plasticity: implications for immune-mediated disease.

Hirahara K, Poholek A, Vahedi G, Laurence A, Kanno Y, Milner JD, O'Shea JJ.

J Allergy Clin Immunol. 2013 May;131(5):1276-87. doi: 10.1016/j.jaci.2013.03.015. Review.

37.

Transcription factors and CD4 T cells seeking identity: masters, minions, setters and spikers.

Vahedi G, Kanno Y, Sartorelli V, O'Shea JJ.

Immunology. 2013 Jul;139(3):294-8. doi: 10.1111/imm.12113. Review.

38.

Tissue inhibitor of metalloproteinase 1 is preferentially expressed in Th1 and Th17 T-helper cell subsets and is a direct STAT target gene.

Adamson A, Ghoreschi K, Rittler M, Chen Q, Sun HW, Vahedi G, Kanno Y, Stetler-Stevenson WG, O'Shea JJ, Laurence A.

PLoS One. 2013;8(3):e59367. doi: 10.1371/journal.pone.0059367. Epub 2013 Mar 26.

39.

Helper T-cell identity and evolution of differential transcriptomes and epigenomes.

Vahedi G, C Poholek A, Hand TW, Laurence A, Kanno Y, O'Shea JJ, Hirahara K.

Immunol Rev. 2013 Mar;252(1):24-40. doi: 10.1111/imr.12037. Review.

40.

Distinct requirements for T-bet in gut innate lymphoid cells.

Sciumé G, Hirahara K, Takahashi H, Laurence A, Villarino AV, Singleton KL, Spencer SP, Wilhelm C, Poholek AC, Vahedi G, Kanno Y, Belkaid Y, O'Shea JJ.

J Exp Med. 2012 Dec 17;209(13):2331-8. doi: 10.1084/jem.20122097. Epub 2012 Dec 3.

41.

STATs shape the active enhancer landscape of T cell populations.

Vahedi G, Takahashi H, Nakayamada S, Sun HW, Sartorelli V, Kanno Y, O'Shea JJ.

Cell. 2012 Nov 21;151(5):981-93. doi: 10.1016/j.cell.2012.09.044.

42.

Interleukin-27 priming of T cells controls IL-17 production in trans via induction of the ligand PD-L1.

Hirahara K, Ghoreschi K, Yang XP, Takahashi H, Laurence A, Vahedi G, Sciumè G, Hall AO, Dupont CD, Francisco LM, Chen Q, Tanaka M, Kanno Y, Sun HW, Sharpe AH, Hunter CA, O'Shea JJ.

Immunity. 2012 Jun 29;36(6):1017-30. doi: 10.1016/j.immuni.2012.03.024. Epub 2012 Jun 21.

43.

Transcriptional and epigenetic control of T helper cell specification: molecular mechanisms underlying commitment and plasticity.

Kanno Y, Vahedi G, Hirahara K, Singleton K, O'Shea JJ.

Annu Rev Immunol. 2012;30:707-31. doi: 10.1146/annurev-immunol-020711-075058. Epub 2012 Jan 6. Review.

44.

Early Th1 cell differentiation is marked by a Tfh cell-like transition.

Nakayamada S, Kanno Y, Takahashi H, Jankovic D, Lu KT, Johnson TA, Sun HW, Vahedi G, Hakim O, Handon R, Schwartzberg PL, Hager GL, O'Shea JJ.

Immunity. 2011 Dec 23;35(6):919-31. doi: 10.1016/j.immuni.2011.11.012.

45.

Helper T-cell differentiation and plasticity: insights from epigenetics.

Hirahara K, Vahedi G, Ghoreschi K, Yang XP, Nakayamada S, Kanno Y, O'Shea JJ, Laurence A.

Immunology. 2011 Nov;134(3):235-45. doi: 10.1111/j.1365-2567.2011.03483.x. Review.

46.

Genomic views of STAT function in CD4+ T helper cell differentiation.

O'Shea JJ, Lahesmaa R, Vahedi G, Laurence A, Kanno Y.

Nat Rev Immunol. 2011 Apr;11(4):239-50. doi: 10.1038/nri2958. Review.

47.

Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5.

Yang XP, Ghoreschi K, Steward-Tharp SM, Rodriguez-Canales J, Zhu J, Grainger JR, Hirahara K, Sun HW, Wei L, Vahedi G, Kanno Y, O'Shea JJ, Laurence A.

Nat Immunol. 2011 Mar;12(3):247-54. doi: 10.1038/ni.1995. Epub 2011 Jan 30.

48.

Discrete roles of STAT4 and STAT6 transcription factors in tuning epigenetic modifications and transcription during T helper cell differentiation.

Wei L, Vahedi G, Sun HW, Watford WT, Takatori H, Ramos HL, Takahashi H, Liang J, Gutierrez-Cruz G, Zang C, Peng W, O'Shea JJ, Kanno Y.

Immunity. 2010 Jun 25;32(6):840-51. doi: 10.1016/j.immuni.2010.06.003.

49.

Diverse targets of the transcription factor STAT3 contribute to T cell pathogenicity and homeostasis.

Durant L, Watford WT, Ramos HL, Laurence A, Vahedi G, Wei L, Takahashi H, Sun HW, Kanno Y, Powrie F, O'Shea JJ.

Immunity. 2010 May 28;32(5):605-15. doi: 10.1016/j.immuni.2010.05.003. Epub 2010 May 20.

50.

Recent advances in intervention in markovian regulatory networks.

Faryabi B, Vahedi G, Datta A, Chamberland JF, Dougherty ER.

Curr Genomics. 2009 Nov;10(7):463-77. doi: 10.2174/138920209789208246.

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