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Items: 23

1.

Improving Drug Penetrability with iRGD Leverages the Therapeutic Response to Sorafenib and Doxorubicin in Hepatocellular Carcinoma.

Schmithals C, Köberle V, Korkusuz H, Pleli T, Kakoschky B, Augusto EA, Ibrahim AA, Arencibia JM, Vafaizadeh V, Groner B, Korf HW, Kronenberger B, Zeuzem S, Vogl TJ, Waidmann O, Piiper A.

Cancer Res. 2015 Aug 1;75(15):3147-54. doi: 10.1158/0008-5472.CAN-15-0395.

2.

Expression of the miR-302/367 cluster in glioblastoma cells suppresses tumorigenic gene expression patterns and abolishes transformation related phenotypes.

Yang CM, Chiba T, Brill B, Delis N, von Manstein V, Vafaizadeh V, Oellerich T, Groner B.

Int J Cancer. 2015 Nov 15;137(10):2296-309. doi: 10.1002/ijc.29606. Epub 2015 Jun 5.

3.

Stat5 Exerts Distinct, Vital Functions in the Cytoplasm and Nucleus of Bcr-Abl+ K562 and Jak2(V617F)+ HEL Leukemia Cells.

Weber A, Borghouts C, Brendel C, Moriggl R, Delis N, Brill B, Vafaizadeh V, Groner B.

Cancers (Basel). 2015 Mar 19;7(1):503-37. doi: 10.3390/cancers7010503.

4.

Inhibiting STAT5 by the BET bromodomain inhibitor JQ1 disrupts human dendritic cell maturation.

Toniolo PA, Liu S, Yeh JE, Moraes-Vieira PM, Walker SR, Vafaizadeh V, Barbuto JA, Frank DA.

J Immunol. 2015 Apr 1;194(7):3180-90. doi: 10.4049/jimmunol.1401635. Epub 2015 Feb 27.

5.

Resistance of Cancer Cells to Targeted Therapies Through the Activation of Compensating Signaling Loops.

von Manstein V, Yang CM, Richter D, Delis N, Vafaizadeh V, Groner B.

Curr Signal Transduct Ther. 2013 Dec;8(3):193-202.

6.

STAT3 induction of miR-146b forms a feedback loop to inhibit the NF-κB to IL-6 signaling axis and STAT3-driven cancer phenotypes.

Xiang M, Birkbak NJ, Vafaizadeh V, Walker SR, Yeh JE, Liu S, Kroll Y, Boldin M, Taganov K, Groner B, Richardson AL, Frank DA.

Sci Signal. 2014 Jan 28;7(310):ra11. doi: 10.1126/scisignal.2004497.

7.

The inhibition of stat5 by a Peptide aptamer ligand specific for the DNA binding domain prevents target gene transactivation and the growth of breast and prostate tumor cells.

Weber A, Borghouts C, Brendel C, Moriggl R, Delis N, Brill B, Vafaizadeh V, Groner B.

Pharmaceuticals (Basel). 2013 Aug 20;6(8):960-87. doi: 10.3390/ph6080960.

8.

Cytokine regulation of mammary gland development and epithelial cell functions through discrete activities of Stat proteins.

Groner B, Vafaizadeh V.

Mol Cell Endocrinol. 2014 Jan 25;382(1):552-559. doi: 10.1016/j.mce.2013.08.019. Epub 2013 Sep 27. No abstract available.

PMID:
24076095
9.

Dual roles of the transcription factor grainyhead-like 2 (GRHL2) in breast cancer.

Werner S, Frey S, Riethdorf S, Schulze C, Alawi M, Kling L, Vafaizadeh V, Sauter G, Terracciano L, Schumacher U, Pantel K, Assmann V.

J Biol Chem. 2013 Aug 9;288(32):22993-3008. doi: 10.1074/jbc.M113.456293. Epub 2013 Jun 29.

10.

Stem cells of the mammary epithelium and their role in breast cancer.

Vafaizadeh V, Groner B.

Eur J Radiol. 2012 Sep;81 Suppl 1:S174-6. doi: 10.1016/S0720-048X(12)70071-2. No abstract available.

PMID:
23083579
11.

STAT3 silencing inhibits glioma single cell infiltration and tumor growth.

Priester M, Copanaki E, Vafaizadeh V, Hensel S, Bernreuther C, Glatzel M, Seifert V, Groner B, Kögel D, Weissenberger J.

Neuro Oncol. 2013 Jul;15(7):840-52. doi: 10.1093/neuonc/not025. Epub 2013 Mar 13. Erratum in: Neuro Oncol. 2013 Oct;15(10):1452.

12.

Transforming growth factor β signaling regulates the invasiveness of normal mammary epithelial cells and the metastasis formation of tumor cells.

Vafaizadeh V, Graab U, Darvishi T, Machado R, Groner B.

Horm Mol Biol Clin Investig. 2012 Jun;10(1):227-39. doi: 10.1515/hmbci-2012-0016.

PMID:
25436679
13.

Stat5 assumes distinct functions in mammary gland development and mammary tumor formation.

Vafaizadeh V, Klemmt PA, Groner B.

Front Biosci (Landmark Ed). 2012 Jan 1;17:1232-50.

PMID:
22201800
14.

c-Kit is required for growth and survival of the cells of origin of Brca1-mutation-associated breast cancer.

Regan JL, Kendrick H, Magnay FA, Vafaizadeh V, Groner B, Smalley MJ.

Oncogene. 2012 Feb 16;31(7):869-83. doi: 10.1038/onc.2011.289. Epub 2011 Jul 18.

PMID:
21765473
15.

The potential of amniotic fluid stem cells for cellular therapy and tissue engineering.

Klemmt PA, Vafaizadeh V, Groner B.

Expert Opin Biol Ther. 2011 Oct;11(10):1297-314. doi: 10.1517/14712598.2011.587800. Epub 2011 May 31. Review.

PMID:
21623704
16.

MicroRNA-dependent regulation of the microenvironment and the epithelial stromal cell interactions in the mouse mammary gland.

Ucar A, Vafaizadeh V, Chowdhury K, Groner B.

Cell Cycle. 2011 Feb 15;10(4):563-5. Epub 2011 Feb 15. No abstract available.

PMID:
21266838
17.

miR-212 and miR-132 are required for epithelial stromal interactions necessary for mouse mammary gland development.

Ucar A, Vafaizadeh V, Jarry H, Fiedler J, Klemmt PA, Thum T, Groner B, Chowdhury K.

Nat Genet. 2010 Dec;42(12):1101-8. doi: 10.1038/ng.709. Epub 2010 Nov 7.

PMID:
21057503
18.

Murine amniotic fluid stem cells contribute mesenchymal but not epithelial components to reconstituted mammary ducts.

Klemmt PA, Vafaizadeh V, Groner B.

Stem Cell Res Ther. 2010 Jul 7;1(3):20. doi: 10.1186/scrt20.

19.

Mammary epithelial reconstitution with gene-modified stem cells assigns roles to Stat5 in luminal alveolar cell fate decisions, differentiation, involution, and mammary tumor formation.

Vafaizadeh V, Klemmt P, Brendel C, Weber K, Doebele C, Britt K, Grez M, Fehse B, Desriviéres S, Groner B.

Stem Cells. 2010 May;28(5):928-38. doi: 10.1002/stem.407.

20.

Stem cells of the breast and cancer therapy.

Groner B, Vafaizadeh V, Brill B, Klemmt P.

Womens Health (Lond). 2010 Mar;6(2):205-19. doi: 10.2217/whe.10.5. Review.

PMID:
20187727
21.

Visualization of Stat3 and Stat5 transactivation activity with specific response element dependent reporter constructs integrated into lentiviral gene transfer vectors.

Gäbel K, Bednorz NL, Klemmt P, Vafaizadeh V, Borghouts C, Groner B.

Horm Mol Biol Clin Investig. 2010 Jan 1;1(3):127-37. doi: 10.1515/HMBCI.2010.017.

PMID:
25961188
22.

Mammary epithelial and breast cancer stem cells.

Groner B, Vafaizadeh V, Brill B, Klemmt P.

Eur J Cancer. 2009 Sep;45 Suppl 1:186-93. doi: 10.1016/S0959-8049(09)70032-2. No abstract available.

PMID:
19775617
23.

The biological functions of the versatile transcription factors STAT3 and STAT5 and new strategies for their targeted inhibition.

Desrivières S, Kunz C, Barash I, Vafaizadeh V, Borghouts C, Groner B.

J Mammary Gland Biol Neoplasia. 2006 Jan;11(1):75-87. Review.

PMID:
16947086

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