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Differential regulation of Ca2+ influx by ORAI channels mediates enamel mineralization.

Eckstein M, Vaeth M, Aulestia FJ, Costiniti V, Kassam SN, Bromage TG, Pedersen P, Issekutz T, Idaghdour Y, Moursi AM, Feske S, Lacruz RS.

Sci Signal. 2019 Apr 23;12(578). pii: eaav4663. doi: 10.1126/scisignal.aav4663.


Tissue resident and follicular Treg cell differentiation is regulated by CRAC channels.

Vaeth M, Wang YH, Eckstein M, Yang J, Silverman GJ, Lacruz RS, Kannan K, Feske S.

Nat Commun. 2019 Mar 12;10(1):1183. doi: 10.1038/s41467-019-08959-8.


Predicting Difference in Mean Survival Time from Reported Hazard Ratios for Cancer Patients.

Røssell Johansen EL, Lousdal ML, Vinther Skriver M, Væth M, Sønbø Kristiansen I, Støvring H.

Med Decis Making. 2019 Apr;39(3):228-238. doi: 10.1177/0272989X19832879. Epub 2019 Mar 5.


ORAI1, STIM1/2, and RYR1 shape subsecond Ca2+ microdomains upon T cell activation.

Diercks BP, Werner R, Weidemüller P, Czarniak F, Hernandez L, Lehmann C, Rosche A, Krüger A, Kaufmann U, Vaeth M, Failla AV, Zobiak B, Kandil FI, Schetelig D, Ruthenbeck A, Meier C, Lodygin D, Flügel A, Ren D, Wolf IMA, Feske S, Guse AH.

Sci Signal. 2018 Dec 18;11(561). pii: eaat0358. doi: 10.1126/scisignal.aat0358.


The role of intention and self-efficacy on the association between breastfeeding of first and second child, a Danish cohort study.

Kronborg H, Foverskov E, Væth M, Maimburg RD.

BMC Pregnancy Childbirth. 2018 Nov 22;18(1):454. doi: 10.1186/s12884-018-2086-5.


Diagnostic accuracy of cone beam computed tomography used for assessment of apical periodontitis: an ex vivo histopathological study on human cadavers.

Kruse C, Spin-Neto R, Evar Kraft DC, Vaeth M, Kirkevang LL.

Int Endod J. 2019 Apr;52(4):439-450. doi: 10.1111/iej.13020. Epub 2018 Oct 25.


STIM1 and STIM2 Mediate Cancer-Induced Inflammation in T Cell Acute Lymphoblastic Leukemia.

Saint Fleur-Lominy S, Maus M, Vaeth M, Lange I, Zee I, Suh D, Liu C, Wu X, Tikhonova A, Aifantis I, Feske S.

Cell Rep. 2018 Sep 11;24(11):3045-3060.e5. doi: 10.1016/j.celrep.2018.08.030.


Functional Interrogation of Primary Human T Cells via CRISPR Genetic Editing.

Chen X, Kozhaya L, Tastan C, Placek L, Dogan M, Horne M, Abblett R, Karhan E, Vaeth M, Feske S, Unutmaz D.

J Immunol. 2018 Sep 1;201(5):1586-1598. doi: 10.4049/jimmunol.1701616. Epub 2018 Jul 18.


Marginal bone level in two Danish cross-sectional population samples in 1997-1998 and 2007-2008.

Bahrami G, Vaeth M, Wenzel A, Isidor F.

Acta Odontol Scand. 2018 Jul;76(5):357-363. doi: 10.1080/00016357.2018.1460492. Epub 2018 Apr 12.


Ion channelopathies of the immune system.

Vaeth M, Feske S.

Curr Opin Immunol. 2018 Jun;52:39-50. doi: 10.1016/j.coi.2018.03.021. Epub 2018 Apr 7. Review.


NFAT control of immune function: New Frontiers for an Abiding Trooper.

Vaeth M, Feske S.

F1000Res. 2018 Mar 2;7:260. doi: 10.12688/f1000research.13426.1. eCollection 2018. Review.


Loss of life expectancy derived from a standardized mortality ratio in Denmark, Finland, Norway and Sweden.

Skriver MV, Væth M, Støvring H.

Scand J Public Health. 2018 Nov;46(7):767-773. doi: 10.1177/1403494817749050. Epub 2018 Jan 31.


Impact of cone beam computed tomography on periapical assessment and treatment planning five to eleven years after surgical endodontic retreatment.

Kruse C, Spin-Neto R, Wenzel A, Vaeth M, Kirkevang LL.

Int Endod J. 2018 Jul;51(7):729-737. doi: 10.1111/iej.12888. Epub 2018 Feb 16.


ORAI1 mutations abolishing store-operated Ca2+ entry cause anhidrotic ectodermal dysplasia with immunodeficiency.

Lian J, Cuk M, Kahlfuss S, Kozhaya L, Vaeth M, Rieux-Laucat F, Picard C, Benson MJ, Jakovcevic A, Bilic K, Martinac I, Stathopulos P, Kacskovics I, Vraetz T, Speckmann C, Ehl S, Issekutz T, Unutmaz D, Feske S.

J Allergy Clin Immunol. 2018 Oct;142(4):1297-1310.e11. doi: 10.1016/j.jaci.2017.10.031. Epub 2017 Nov 16.


Charcot-Marie-Tooth disease in Denmark: a nationwide register-based study of mortality, prevalence and incidence.

Vaeth S, Vaeth M, Andersen H, Christensen R, Jensen UB.

BMJ Open. 2017 Nov 3;7(11):e018048. doi: 10.1136/bmjopen-2017-018048.


Quality aspects of ex vivo root canal treatments done by undergraduate dental students using four different endodontic treatment systems.

Jungnickel L, Kruse C, Vaeth M, Kirkevang LL.

Acta Odontol Scand. 2018 Apr;76(3):169-174. doi: 10.1080/00016357.2017.1396494. Epub 2017 Oct 29.


Store-Operated Ca2+ Entry Controls Clonal Expansion of T Cells through Metabolic Reprogramming.

Vaeth M, Maus M, Klein-Hessling S, Freinkman E, Yang J, Eckstein M, Cameron S, Turvey SE, Serfling E, Berberich-Siebelt F, Possemato R, Feske S.

Immunity. 2017 Oct 17;47(4):664-679.e6. doi: 10.1016/j.immuni.2017.09.003. Epub 2017 Oct 11.


NFATc1 controls the cytotoxicity of CD8+ T cells.

Klein-Hessling S, Muhammad K, Klein M, Pusch T, Rudolf R, Flöter J, Qureischi M, Beilhack A, Vaeth M, Kummerow C, Backes C, Schoppmeyer R, Hahn U, Hoth M, Bopp T, Berberich-Siebelt F, Patra A, Avots A, Müller N, Schulze A, Serfling E.

Nat Commun. 2017 Sep 11;8(1):511. doi: 10.1038/s41467-017-00612-6.


Store-operated Ca2+ entry controls ameloblast cell function and enamel development.

Eckstein M, Vaeth M, Fornai C, Vinu M, Bromage TG, Nurbaeva MK, Sorge JL, Coelho PG, Idaghdour Y, Feske S, Lacruz RS.

JCI Insight. 2017 Mar 23;2(6):e91166. doi: 10.1172/jci.insight.91166.


Marginal Bone Loss after Ten Years in an Adult Danish Population: A Radiographic Study.

Bahrami G, Vaeth M, Wenzel A, Isidor F.

Oral Health Prev Dent. 2017;15(2):183-189. doi: 10.3290/j.ohpd.a37932.


ORAI2 modulates store-operated calcium entry and T cell-mediated immunity.

Vaeth M, Yang J, Yamashita M, Zee I, Eckstein M, Knosp C, Kaufmann U, Karoly Jani P, Lacruz RS, Flockerzi V, Kacskovics I, Prakriya M, Feske S.

Nat Commun. 2017 Mar 15;8:14714. doi: 10.1038/ncomms14714.


Store-operated Ca2+ entry regulates Ca2+-activated chloride channels and eccrine sweat gland function.

Concepcion AR, Vaeth M, Wagner LE 2nd, Eckstein M, Hecht L, Yang J, Crottes D, Seidl M, Shin HP, Weidinger C, Cameron S, Turvey SE, Issekutz T, Meyts I, Lacruz RS, Cuk M, Yule DI, Feske S.

J Clin Invest. 2016 Nov 1;126(11):4303-4318. doi: 10.1172/JCI89056. Epub 2016 Oct 10.


Women's experience of childbirth - A five year follow-up of the randomised controlled trial "Ready for Child Trial".

Maimburg RD, Væth M, Dahlen H.

Women Birth. 2016 Oct;29(5):450-454. doi: 10.1016/j.wombi.2016.02.003. Epub 2016 Mar 30.


The impact of smoking on marginal bone loss in a 10-year prospective longitudinal study.

Bahrami G, Vaeth M, Kirkevang LL, Wenzel A, Isidor F.

Community Dent Oral Epidemiol. 2017 Feb;45(1):59-65. doi: 10.1111/cdoe.12260. Epub 2016 Sep 21.


Exogenous TNFR2 activation protects from acute GvHD via host T reg cell expansion.

Chopra M, Biehl M, Steinfatt T, Brandl A, Kums J, Amich J, Vaeth M, Kuen J, Holtappels R, Podlech J, Mottok A, Kraus S, Jordán-Garrote AL, Bäuerlein CA, Brede C, Ribechini E, Fick A, Seher A, Polz J, Ottmüller KJ, Baker J, Nishikii H, Ritz M, Mattenheimer K, Schwinn S, Winter T, Schäfer V, Krappmann S, Einsele H, Müller TD, Reddehase MJ, Lutz MB, Männel DN, Berberich-Siebelt F, Wajant H, Beilhack A.

J Exp Med. 2016 Aug 22;213(9):1881-900. doi: 10.1084/jem.20151563. Epub 2016 Aug 15.


Identification of PGAM5 as a Mammalian Protein Histidine Phosphatase that Plays a Central Role to Negatively Regulate CD4(+) T Cells.

Panda S, Srivastava S, Li Z, Vaeth M, Fuhs SR, Hunter T, Skolnik EY.

Mol Cell. 2016 Aug 4;63(3):457-69. doi: 10.1016/j.molcel.2016.06.021. Epub 2016 Jul 21.


Store-Operated Ca(2+) Entry in Follicular T Cells Controls Humoral Immune Responses and Autoimmunity.

Vaeth M, Eckstein M, Shaw PJ, Kozhaya L, Yang J, Berberich-Siebelt F, Clancy R, Unutmaz D, Feske S.

Immunity. 2016 Jun 21;44(6):1350-64. doi: 10.1016/j.immuni.2016.04.013. Epub 2016 May 31.


Prediction of periapical status and tooth extraction.

Kirkevang LL, Ørstavik D, Bahrami G, Wenzel A, Vaeth M.

Int Endod J. 2017 Jan;50(1):5-14. doi: 10.1111/iej.12581. Epub 2015 Dec 23.


Comparison of Riboflavin and Toluidine Blue O as Photosensitizers for Photoactivated Disinfection on Endodontic and Periodontal Pathogens In Vitro.

Nielsen HK, Garcia J, Væth M, Schlafer S.

PLoS One. 2015 Oct 15;10(10):e0140720. doi: 10.1371/journal.pone.0140720. eCollection 2015.


Ca2+ Signaling but Not Store-Operated Ca2+ Entry Is Required for the Function of Macrophages and Dendritic Cells.

Vaeth M, Zee I, Concepcion AR, Maus M, Shaw P, Portal-Celhay C, Zahra A, Kozhaya L, Weidinger C, Philips J, Unutmaz D, Feske S.

J Immunol. 2015 Aug 1;195(3):1202-17. doi: 10.4049/jimmunol.1403013. Epub 2015 Jun 24.


Lack of evidence of increased risk of bacterial transmission during cystic fibrosis educational programmes.

Ridderberg W, Andersen C, Væth M, Bregnballe V, Nørskov-Lauritsen N, Schiøtz PO.

J Cyst Fibros. 2016 Jan;15(1):109-15. doi: 10.1016/j.jcf.2015.04.007. Epub 2015 May 21.


Postpartum depression among first-time mothers - results from a parallel randomised trial.

Maimburg RD, Vaeth M.

Sex Reprod Healthc. 2015 Jun;6(2):95-100. doi: 10.1016/j.srhc.2015.01.003. Epub 2015 Jan 15.


STIM1 controls T cell-mediated immune regulation and inflammation in chronic infection.

Desvignes L, Weidinger C, Shaw P, Vaeth M, Ribierre T, Liu M, Fergus T, Kozhaya L, McVoy L, Unutmaz D, Ernst JD, Feske S.

J Clin Invest. 2015 Jun;125(6):2347-62. doi: 10.1172/JCI80273. Epub 2015 May 4.


Economic and health implications of routine CBCT examination before surgical removal of the mandibular third molar in the Danish population.

Petersen LB, Olsen KR, Matzen LH, Vaeth M, Wenzel A.

Dentomaxillofac Radiol. 2015;44(6):20140406. doi: 10.1259/dmfr.20140406. Epub 2015 Mar 18.


TCAIM decreases T cell priming capacity of dendritic cells by inhibiting TLR-induced Ca2+ influx and IL-2 production.

Vogel SZ, Schlickeiser S, Jürchott K, Akyuez L, Schumann J, Appelt C, Vogt K, Schröder M, Vaeth M, Berberich-Siebelt F, Lutz MB, Grütz G, Sawitzki B.

J Immunol. 2015 Apr 1;194(7):3136-46. doi: 10.4049/jimmunol.1400713. Epub 2015 Mar 6.


Breastfeeding and introduction of complementary food in Danish infants.

Kronborg H, Foverskov E, Væth M.

Scand J Public Health. 2015 Mar;43(2):138-45. doi: 10.1177/1403494814567171. Epub 2015 Jan 28.


NFAT1 deficit and NFAT2 deficit attenuate EAE via different mechanisms.

Dietz L, Frommer F, Vogel AL, Vaeth M, Serfling E, Waisman A, Buttmann M, Berberich-Siebelt F.

Eur J Immunol. 2015 May;45(5):1377-89. doi: 10.1002/eji.201444638. Epub 2015 Feb 19.


Implications of less-than-perfect reliability of clinical parameters for the misclassification of periodontitis.

Corraini P, Lopez R, Vaeth M.

Community Dent Oral Epidemiol. 2015 Apr;43(2):183-92. doi: 10.1111/cdoe.12142. Epub 2015 Jan 27.


Selective NFAT targeting in T cells ameliorates GvHD while maintaining antitumor activity.

Vaeth M, Bäuerlein CA, Pusch T, Findeis J, Chopra M, Mottok A, Rosenwald A, Beilhack A, Berberich-Siebelt F.

Proc Natl Acad Sci U S A. 2015 Jan 27;112(4):1125-30. doi: 10.1073/pnas.1409290112. Epub 2015 Jan 12.


Immature dendritic cells convert anergic nonregulatory T cells into Foxp3- IL-10+ regulatory T cells by engaging CD28 and CTLA-4.

Pletinckx K, Vaeth M, Schneider T, Beyersdorf N, Hünig T, Berberich-Siebelt F, Lutz MB.

Eur J Immunol. 2015 Feb;45(2):480-91. doi: 10.1002/eji.201444991. Epub 2014 Dec 2.


The mitochondrial protein TCAIM regulates activation of T cells and thereby promotes tolerance induction of allogeneic transplants.

Schumann J, Stanko K, Woertge S, Appelt C, Schumann M, Kühl AA, Panov I, Schliesser U, Vogel S, Ahrlich S, Vaeth M, Berberich-Siebelt F, Waisman A, Sawitzki B.

Am J Transplant. 2014 Dec;14(12):2723-35. doi: 10.1111/ajt.12941. Epub 2014 Oct 31.


Prognostic value of the full-scale Periapical Index.

Kirkevang LL, Ørstavik D, Wenzel A, Vaeth M.

Int Endod J. 2015 Nov;48(11):1051-8. doi: 10.1111/iej.12402. Epub 2014 Nov 24.


Predictors for early introduction of solid food among Danish mothers and infants: an observational study.

Kronborg H, Foverskov E, Væth M.

BMC Pediatr. 2014 Oct 1;14:243. doi: 10.1186/1471-2431-14-243.


CD4⁺ and CD8⁺ T cell-dependent antiviral immunity requires STIM1 and STIM2.

Shaw PJ, Weidinger C, Vaeth M, Luethy K, Kaech SM, Feske S.

J Clin Invest. 2014 Oct;124(10):4549-63. doi: 10.1172/JCI76602. Epub 2014 Aug 26.


Risk of second primary lung cancer in women after radiotherapy for breast cancer.

Grantzau T, Thomsen MS, Væth M, Overgaard J.

Radiother Oncol. 2014 Jun;111(3):366-73. doi: 10.1016/j.radonc.2014.05.004. Epub 2014 Jun 5.


Five-year evaluation of a low-shrinkage Silorane resin composite material: a randomized clinical trial.

Schmidt M, Dige I, Kirkevang LL, Vaeth M, Hørsted-Bindslev P.

Clin Oral Investig. 2015 Mar;19(2):245-51. doi: 10.1007/s00784-014-1238-x. Epub 2014 Apr 1.


Follicular regulatory T cells control humoral autoimmunity via NFAT2-regulated CXCR5 expression.

Vaeth M, Müller G, Stauss D, Dietz L, Klein-Hessling S, Serfling E, Lipp M, Berberich I, Berberich-Siebelt F.

J Exp Med. 2014 Mar 10;211(3):545-61. doi: 10.1084/jem.20130604. Epub 2014 Mar 3.


Ten-year follow-up of root filled teeth: a radiographic study of a Danish population.

Kirkevang LL, Vaeth M, Wenzel A.

Int Endod J. 2014 Oct;47(10):980-8. doi: 10.1111/iej.12245. Epub 2014 Feb 17.


Is thermography useful for assessment of postoperative inflammation after surgical removal of mandibular third molars when methylprednisolone is administered and how does it correlate with patients' perception of swelling?

Christensen J, Matzen LH, Schou S, Væth M, Wenzel A.

J Oral Maxillofac Surg. 2014 Mar;72(3):463-9. doi: 10.1016/j.joms.2013.09.035. Epub 2013 Oct 5.


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