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Items: 40

1.

PDE4 Inhibition as a therapeutic target for alcoholic liver disease: from bedside to bench.

Rodriguez WE, Wahlang B, Wang Y, Zhang J, Vadhanam MV, Joshi-Barve S, Bauer P, Cannon R, Ahmadi AR, Sun Z, Cameron A, Barve S, Maldonado C, McClain C, Gobejishvili L.

Hepatology. 2019 May 13. doi: 10.1002/hep.30761. [Epub ahead of print]

PMID:
31081957
2.

A natural molecule, urolithin A, downregulates androgen receptor activation and suppresses growth of prostate cancer.

Dahiya NR, Chandrasekaran B, Kolluru V, Ankem M, Damodaran C, Vadhanam MV.

Mol Carcinog. 2018 Oct;57(10):1332-1341. doi: 10.1002/mc.22848. Epub 2018 Aug 1. Erratum in: Mol Carcinog. 2019 Feb;58(2):305.

PMID:
30069922
3.

Development of a goat model for evaluation of withaferin A: Cervical implants for the treatment of cervical intraepithelial neoplasia.

Sherwood LC, Aqil F, Vadhanam MV, Jeyabalan J, Munagala R, Hoetker D, Srivastava S, Singh IP, Cambron S, O'Toole M, Spencer W, Parker LP, Gupta RC.

Exp Mol Pathol. 2017 Dec;103(3):320-329. doi: 10.1016/j.yexmp.2017.11.008. Epub 2017 Nov 21.

4.

Chemoprevention of Rat Mammary Carcinogenesis by Apiaceae Spices.

Aqil F, Jeyabalan J, Munagala R, Ravoori S, Vadhanam MV, Schultz DJ, Gupta RC.

Int J Mol Sci. 2017 Feb 16;18(2). pii: E425. doi: 10.3390/ijms18020425.

5.

Exosomal formulation of anthocyanidins against multiple cancer types.

Munagala R, Aqil F, Jeyabalan J, Agrawal AK, Mudd AM, Kyakulaga AH, Singh IP, Vadhanam MV, Gupta RC.

Cancer Lett. 2017 May 1;393:94-102. doi: 10.1016/j.canlet.2017.02.004. Epub 2017 Feb 12.

6.

Effect of phytochemical intervention on dibenzo[a,l]pyrene-induced DNA adduct formation.

Russell GK, Gupta RC, Vadhanam MV.

Mutat Res. 2015 Apr;774:25-32. doi: 10.1016/j.mrfmmm.2015.02.003. Epub 2015 Feb 25.

7.

Detection of anthocyanins/anthocyanidins in animal tissues.

Aqil F, Vadhanam MV, Jeyabalan J, Cai J, Singh IP, Gupta RC.

J Agric Food Chem. 2014 May 7;62(18):3912-8. doi: 10.1021/jf500467b. Epub 2014 Apr 21.

8.

Curcumin implants, not curcumin diet, inhibit estrogen-induced mammary carcinogenesis in ACI rats.

Bansal SS, Kausar H, Vadhanam MV, Ravoori S, Pan J, Rai SN, Gupta RC.

Cancer Prev Res (Phila). 2014 Apr;7(4):456-65. doi: 10.1158/1940-6207.CAPR-13-0248. Epub 2014 Feb 5.

9.

Polymeric implants for the delivery of green tea polyphenols.

Cao P, Jeyabalan J, Aqil F, Ravoori S, Gupta RC, Vadhanam MV.

J Pharm Sci. 2014 Mar;103(3):945-51. doi: 10.1002/jps.23864. Epub 2014 Jan 24.

10.

Chemopreventive and therapeutic activity of dietary blueberry against estrogen-mediated breast cancer.

Jeyabalan J, Aqil F, Munagala R, Annamalai L, Vadhanam MV, Gupta RC.

J Agric Food Chem. 2014 May 7;62(18):3963-71. doi: 10.1021/jf403734j. Epub 2014 Apr 15.

11.

MicroRNA 'signature' during estrogen-mediated mammary carcinogenesis and its reversal by ellagic acid intervention.

Munagala R, Aqil F, Vadhanam MV, Gupta RC.

Cancer Lett. 2013 Oct 10;339(2):175-84. doi: 10.1016/j.canlet.2013.06.012. Epub 2013 Jun 18.

12.

Featuring the special issue editors Dr. M.N.V. Ravi Kumar, Dr. Manicka V. Vadhanam and Dr. Jamal M. Arif.

Ravi Kumar MN, Vadhanam MV, Arif JM.

Cancer Lett. 2013 Jun 28;334(1):1-2. doi: 10.1016/j.canlet.2013.03.013. Epub 2013 Mar 22. No abstract available.

PMID:
23523872
13.

Anti-proliferative activity and protection against oxidative DNA damage by punicalagin isolated from pomegranate husk.

Aqil F, Munagala R, Vadhanam MV, Kausar H, Jeyabalan J, Schultz DJ, Gupta RC.

Food Res Int. 2012 Nov 1;49(1):345-353. Epub 2012 Aug 7.

14.

Bioavailability of phytochemicals and its enhancement by drug delivery systems.

Aqil F, Munagala R, Jeyabalan J, Vadhanam MV.

Cancer Lett. 2013 Jun 28;334(1):133-41. doi: 10.1016/j.canlet.2013.02.032. Epub 2013 Feb 19. Review.

15.

Cucurbitacin B potently suppresses non-small-cell lung cancer growth: identification of intracellular thiols as critical targets.

Kausar H, Munagala R, Bansal SS, Aqil F, Vadhanam MV, Gupta RC.

Cancer Lett. 2013 May 10;332(1):35-45. doi: 10.1016/j.canlet.2013.01.008. Epub 2013 Jan 20.

PMID:
23340170
16.

Vaginal cells of smokers are more resistant to human papillomavirus infection than that of non-smokers.

Moktar A, Ravoori S, Vadhanam MV, Pan J, Rai SN, Jenson AB, Parker LP, Gupta RC.

Exp Mol Pathol. 2012 Dec;93(3):422-7. doi: 10.1016/j.yexmp.2012.10.016. Epub 2012 Nov 5.

17.

Oxidative DNA adducts detected in vitro from redox activity of cigarette smoke constituents.

Vadhanam MV, Thaiparambil J, Gairola CG, Gupta RC.

Chem Res Toxicol. 2012 Nov 19;25(11):2499-504. doi: 10.1021/tx300312f. Epub 2012 Oct 26.

PMID:
22994544
18.

Multi-layer polymeric implants for sustained release of chemopreventives.

Aqil F, Jeyabalan J, Kausar H, Bansal SS, Sharma RJ, Singh IP, Vadhanam MV, Gupta RC.

Cancer Lett. 2012 Dec 29;326(1):33-40. doi: 10.1016/j.canlet.2012.07.017. Epub 2012 Jul 20.

19.

Controlled-release systemic delivery - a new concept in cancer chemoprevention.

Gupta RC, Bansal SS, Aqil F, Jeyabalan J, Cao P, Kausar H, Russell GK, Munagala R, Ravoori S, Vadhanam MV.

Carcinogenesis. 2012 Aug;33(8):1608-15. doi: 10.1093/carcin/bgs209. Epub 2012 Jun 13.

20.

Inhibition of estrogen-mediated mammary tumorigenesis by blueberry and black raspberry.

Ravoori S, Vadhanam MV, Aqil F, Gupta RC.

J Agric Food Chem. 2012 Jun 6;60(22):5547-55. doi: 10.1021/jf205325p. Epub 2012 May 22.

PMID:
22571764
21.

Enhanced activity of punicalagin delivered via polymeric implants against benzo[a]pyrene-induced DNA adducts.

Aqil F, Vadhanam MV, Gupta RC.

Mutat Res. 2012 Mar 18;743(1-2):59-66. doi: 10.1016/j.mrgentox.2011.12.022. Epub 2012 Jan 5.

22.

Controlled systemic delivery by polymeric implants enhances tissue and plasma curcumin levels compared with oral administration.

Bansal SS, Kausar H, Vadhanam MV, Ravoori S, Gupta RC.

Eur J Pharm Biopharm. 2012 Apr;80(3):571-7. doi: 10.1016/j.ejpb.2011.12.009. Epub 2011 Dec 30.

23.

Oxidative DNA damage following microsome/Cu(II)-mediated activation of the estrogens, 17β-estradiol, equilenin, and equilin: role of reactive oxygen species.

Spencer WA, Vadhanam MV, Jeyabalan J, Gupta RC.

Chem Res Toxicol. 2012 Feb 20;25(2):305-14. doi: 10.1021/tx200356v. Epub 2012 Jan 6.

PMID:
22126130
24.

Sustained overexpression of CYP1A1 and 1B1 and steady accumulation of DNA adducts by low-dose, continuous exposure to benzo[a]pyrene by polymeric implants.

Jeyabalan J, Vadhanam MV, Ravoori S, Gupta RC.

Chem Res Toxicol. 2011 Nov 21;24(11):1937-43. doi: 10.1021/tx2002788. Epub 2011 Oct 12.

PMID:
21942922
25.

Curcumin implants for continuous systemic delivery: safety and biocompatibility.

Bansal SS, Kausar H, Aqil F, Jeyabalan J, Vadhanam MV, Gupta RC, Ravoori S.

Drug Deliv Transl Res. 2011 Aug;1(4):332-41. doi: 10.1007/s13346-011-0028-0.

PMID:
25788367
26.

Chemoprevention of mammary carcinogenesis by sustained systemic delivery of ellagic acid.

Vadhanam MV, Ravoori S, Aqil F, Gupta RC.

Eur J Cancer Prev. 2011 Nov;20(6):484-91. doi: 10.1097/CEJ.0b013e3283498e00.

PMID:
21768881
27.

Cigarette smoke condensate-induced oxidative DNA damage and its removal in human cervical cancer cells.

Moktar A, Singh R, Vadhanam MV, Ravoori S, Lillard JW, Gairola CG, Gupta RC.

Int J Oncol. 2011 Oct;39(4):941-7. doi: 10.3892/ijo.2011.1106. Epub 2011 Jun 29.

28.

Sustained systemic delivery of green tea polyphenols by polymeric implants significantly diminishes benzo[a]pyrene-induced DNA adducts.

Cao P, Vadhanam MV, Spencer WA, Cai J, Gupta RC.

Chem Res Toxicol. 2011 Jun 20;24(6):877-86. doi: 10.1021/tx2000625. Epub 2011 May 31.

29.

Advanced drug delivery systems of curcumin for cancer chemoprevention.

Bansal SS, Goel M, Aqil F, Vadhanam MV, Gupta RC.

Cancer Prev Res (Phila). 2011 Aug;4(8):1158-71. doi: 10.1158/1940-6207.CAPR-10-0006. Epub 2011 May 5. Review.

30.

Development and in vitro-in vivo evaluation of polymeric implants for continuous systemic delivery of curcumin.

Bansal SS, Vadhanam MV, Gupta RC.

Pharm Res. 2011 May;28(5):1121-30. doi: 10.1007/s11095-011-0375-z. Epub 2011 Feb 11.

PMID:
21311958
31.

Early changes in gene expression induced by tobacco smoke: Evidence for the importance of estrogen within lung tissue.

Meireles SI, Esteves GH, Hirata R Jr, Peri S, Devarajan K, Slifker M, Mosier SL, Peng J, Vadhanam MV, Hurst HE, Neves EJ, Reis LF, Gairola CG, Gupta RC, Clapper ML.

Cancer Prev Res (Phila). 2010 Jun;3(6):707-17. doi: 10.1158/1940-6207.CAPR-09-0162. Epub 2010 Jun 1.

32.

Cigarette smoke-induced DNA damage and repair detected by the comet assay in HPV-transformed cervical cells.

Moktar A, Ravoori S, Vadhanam MV, Gairola CG, Gupta RC.

Int J Oncol. 2009 Dec;35(6):1297-304.

33.

Dietary berries and ellagic acid prevent oxidative DNA damage and modulate expression of DNA repair genes.

Aiyer HS, Vadhanam MV, Stoyanova R, Caprio GD, Clapper ML, Gupta RC.

Int J Mol Sci. 2008 Mar;9(3):327-41. Epub 2008 Mar 12.

34.

Time-dependent formation of 8-oxo-deoxyguanosine in the lungs of mice exposed to cigarette smoke.

Thaiparambil JT, Vadhanam MV, Srinivasan C, Gairola CG, Gupta RC.

Chem Res Toxicol. 2007 Dec;20(12):1737-40. Epub 2007 Nov 22.

PMID:
18031018
35.

Mammary tumor induction in ACI rats exposed to low levels of 17beta-estradiol.

Ravoori S, Vadhanam MV, Sahoo S, Srinivasan C, Gupta RC.

Int J Oncol. 2007 Jul;31(1):113-20.

PMID:
17549411
36.

Modulation of novel DNA adducts during human uterine cervix cancer progression.

Ravoori S, Vadhanam MV, Davey DD, Srinivasan C, Nagarajan B, Gupta RC.

Int J Oncol. 2006 Dec;29(6):1437-43.

PMID:
17088982
37.

Formation of benzylic-DNA adducts resulting from 7,12-dimethylbenz[a]anthracene in vivo.

Ravi Kumar MN, Vadhanam MV, Horn J, Flesher JW, Gupta RC.

Chem Res Toxicol. 2005 Apr;18(4):686-91.

PMID:
15833028
38.
39.

A rapid screening assay for antioxidant potential of natural and synthetic agents in vitro.

Srinivasan P, Vadhanam MV, Arif JM, Gupta RC.

Int J Oncol. 2002 May;20(5):983-6.

PMID:
11956593
40.

Effect of cigarette smoke exposure on the modulation of 8-oxo-2'-deoxyguanosine in rat lungs as analyzed by 32P-postlabeling and HPLC-ECD.

Arif JM, Vadhanam MV, De Groot AJ, Van Zeeland AA, Gairola CG, Gupta RC.

Int J Oncol. 2001 Oct;19(4):763-6.

PMID:
11562752

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