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Organ Procurement Organization Run Department of Motor Vehicle Registration and Drivers Licensing Offices Leads to Increased Organ Donor First Person Authorization Registrations.

Dageforde LA, Muren W, Chang SH, Vachharajani N, Brockmeier D, Yu J, Anderson B, Shenoy S, Lin Y, Khan A, Wellen J, Chapman W, Doyle M.

Transplantation. 2019 Jun 24. doi: 10.1097/TP.0000000000002842. [Epub ahead of print]


Pathologic Response to Pretransplant Locoregional Therapy is Predictive of Patient Outcome After Liver Transplantation for Hepatocellular Carcinoma: Analysis From the US Multicenter HCC Transplant Consortium.

DiNorcia J, Florman SS, Haydel B, Tabrizian P, Ruiz RM, Klintmalm GB, Senguttuvan S, Lee DD, Taner CB, Verna EC, Halazun KJ, Hoteit M, Levine MH, Chapman WC, Vachharajani N, Aucejo F, Nguyen MH, Melcher ML, Tevar AD, Humar A, Mobley C, Ghobrial M, Nydam TL, Amundsen B, Markmann JF, Berumen J, Hemming AW, Langnas AN, Carney CA, Sudan DL, Hong JC, Kim J, Zimmerman MA, Rana A, Kueht ML, Jones CM, Fishbein TM, Markovic D, Busuttil RW, Agopian VG.

Ann Surg. 2019 Mar 5. doi: 10.1097/SLA.0000000000003253. [Epub ahead of print]


The short-chain fatty acid pentanoate suppresses autoimmunity by modulating the metabolic-epigenetic crosstalk in lymphocytes.

Luu M, Pautz S, Kohl V, Singh R, Romero R, Lucas S, Hofmann J, Raifer H, Vachharajani N, Carrascosa LC, Lamp B, Nist A, Stiewe T, Shaul Y, Adhikary T, Zaiss MM, Lauth M, Steinhoff U, Visekruna A.

Nat Commun. 2019 Feb 15;10(1):760. doi: 10.1038/s41467-019-08711-2.


Systemic Therapy for Combined Hepatocellular-Cholangiocarcinoma: A Single-Institution Experience.

Trikalinos NA, Zhou A, Doyle MBM, Fowler KJ, Morton A, Vachharajani N, Amin M, Keller JW, Chapman WC, Brunt EM, Tan BR.

J Natl Compr Canc Netw. 2018 Oct;16(10):1193-1199. doi: 10.6004/jnccn.2018.7053.


Organ procurement center allows for daytime liver transplantation with less resource utilization: May address burnout, pipeline, and safety for field of transplantation.

Lindemann J, Dageforde LA, Brockmeier D, Vachharajani N, Scherer M, Chapman W, Doyle MBM.

Am J Transplant. 2019 May;19(5):1296-1304. doi: 10.1111/ajt.15129. Epub 2018 Oct 19.


Mini-incision versus hand-assisted laparoscopic donor nephrectomy in living-donor kidney transplantation: A retrospective cohort study.

Subramanian T, Dageforde LA, Vachharajani N, Wellen J, Doyle MBM, Lin Y, Khan A, Senter-Zapata M, Chapman W, Shenoy S.

Int J Surg. 2018 May;53:339-344. doi: 10.1016/j.ijsu.2018.04.003. Epub 2018 Apr 11.


Cost Evaluation of a Donation after Cardiac Death Program: How Cost per Organ Compares to Other Donor Types.

Lindemann J, Dageforde LA, Vachharajani N, Stahlschmidt E, Brockmeier D, Wellen JR, Khan A, Chapman WC, Doyle MM.

J Am Coll Surg. 2018 May;226(5):909-916. doi: 10.1016/j.jamcollsurg.2018.02.005. Epub 2018 Mar 2.


Patient and Graft Survival: Biliary Complications after Liver Transplantation.

Senter-Zapata M, Khan AS, Subramanian T, Vachharajani N, Dageforde LA, Wellen JR, Shenoy S, Majella Doyle MB, Chapman WC.

J Am Coll Surg. 2018 Apr;226(4):484-494. doi: 10.1016/j.jamcollsurg.2017.12.039. Epub 2018 Jan 31.


Serum alpha-fetoprotein level per total tumor volume as a predictor of recurrence of hepatocellular carcinoma after resection.

Sharma Y, Weaver MJ, Ludwig DR, Fowler K, Vachharajani N, Chapman WC, Crippin JS.

Surgery. 2018 May;163(5):1002-1007. doi: 10.1016/j.surg.2017.10.063. Epub 2017 Dec 25.


The Microbial Metabolite Butyrate Induces Expression of Th1-Associated Factors in CD4+ T Cells.

Kespohl M, Vachharajani N, Luu M, Harb H, Pautz S, Wolff S, Sillner N, Walker A, Schmitt-Kopplin P, Boettger T, Renz H, Offermanns S, Steinhoff U, Visekruna A.

Front Immunol. 2017 Aug 28;8:1036. doi: 10.3389/fimmu.2017.01036. eCollection 2017.


Transcription factor c-Rel is indispensable for generation of thymic but not of peripheral Foxp3+ regulatory T cells.

Luu M, Jenike E, Vachharajani N, Visekruna A.

Oncotarget. 2017 Apr 13;8(32):52678-52689. doi: 10.18632/oncotarget.17079. eCollection 2017 Aug 8.


Prevention of colitis-associated cancer by selective targeting of immunoproteasome subunit LMP7.

Vachharajani N, Joeris T, Luu M, Hartmann S, Pautz S, Jenike E, Pantazis G, Prinz I, Hofer MJ, Steinhoff U, Visekruna A.

Oncotarget. 2017 Jan 10;8(31):50447-50459. doi: 10.18632/oncotarget.14579. eCollection 2017 Aug 1.


Long-term outcome of upper extremity arteriovenous fistula using pSLOT: single-center longitudinal follow-up using a protocol-based approach.

Darcy M, Vachharajani N, Zhang T, Mani N, Kim SK, Matson S, Wood M, Shenoy S.

J Vasc Access. 2017 Nov 17;18(6):515-521. doi: 10.5301/jva.5000764. Epub 2017 Jul 29.


The influence of functional warm ischemia time on DCD liver transplant recipients' outcomes.

Coffey JC, Wanis KN, Monbaliu D, Gilbo N, Selzner M, Vachharajani N, Levstik MA, Marquez M, Doyle MBM, Pirenne J, Grant D, Heimbach JK, Chapman W, Vogt K, Hernandez-Alejandro R.

Clin Transplant. 2017 Oct;31(10). doi: 10.1111/ctr.13068. Epub 2017 Aug 29.


Impact of Pretransplant Bridging Locoregional Therapy for Patients With Hepatocellular Carcinoma Within Milan Criteria Undergoing Liver Transplantation: Analysis of 3601 Patients From the US Multicenter HCC Transplant Consortium.

Agopian VG, Harlander-Locke MP, Ruiz RM, Klintmalm GB, Senguttuvan S, Florman SS, Haydel B, Hoteit M, Levine MH, Lee DD, Taner CB, Verna EC, Halazun KJ, Abdelmessih R, Tevar AD, Humar A, Aucejo F, Chapman WC, Vachharajani N, Nguyen MH, Melcher ML, Nydam TL, Mobley C, Ghobrial RM, Amundsen B, Markmann JF, Langnas AN, Carney CA, Berumen J, Hemming AW, Sudan DL, Hong JC, Kim J, Zimmerman MA, Rana A, Kueht ML, Jones CM, Fishbein TM, Busuttil RW.

Ann Surg. 2017 Sep;266(3):525-535. doi: 10.1097/SLA.0000000000002381.


Prediction of Hepatocellular Carcinoma Recurrence Beyond Milan Criteria After Resection: Validation of a Clinical Risk Score in an International Cohort.

Zheng J, Chou JF, Gönen M, Vachharajani N, Chapman WC, Majella Doyle MB, Turcotte S, Vandenbroucke-Menu F, Lapointe R, Buettner S, Groot Koerkamp B, Ijzermans JNM, Chan CY, Goh BKP, Teo JY, Kam JH, Jeyaraj PR, Cheow PC, Chung AYF, Chow PKH, Ooi LLPJ, Balachandran VP, Kingham TP, Allen PJ, D'Angelica MI, DeMatteo RP, Jarnagin WR, Lee SY.

Ann Surg. 2017 Oct;266(4):693-701. doi: 10.1097/SLA.0000000000002360.


Development of immune response to tissue-restricted self-antigens in simultaneous kidney-pancreas transplant recipients with acute rejection.

Gunasekaran M, Vachharajani N, Gaut JP, Maw TT, Delos Santos R, Shenoy S, Chapman WC, Wellen J, Mohanakumar T.

Clin Transplant. 2017 Aug;31(8). doi: 10.1111/ctr.13009. Epub 2017 Jun 21.


Neoadjuvant Locoregional Therapy and Recurrent Hepatocellular Carcinoma after Liver Transplantation.

Xu M, Doyle MM, Banan B, Vachharajani N, Wang X, Saad N, Fowler K, Brunt EM, Lin Y, Chapman WC.

J Am Coll Surg. 2017 Jul;225(1):28-40. doi: 10.1016/j.jamcollsurg.2017.03.015. Epub 2017 Apr 9. Erratum in: J Am Coll Surg. 2018 Jan;226(1):115.


Liver Transplantation for Malignant Primary Pediatric Hepatic Tumors.

Khan AS, Brecklin B, Vachharajani N, Subramanian V, Nadler M, Stoll J, Turmelle Y, Lowell JA, Chapman WC, Doyle MM.

J Am Coll Surg. 2017 Jul;225(1):103-113. doi: 10.1016/j.jamcollsurg.2017.02.006. Epub 2017 Feb 20.


Reducing peripherally inserted central catheters in the neonatal intensive care unit.

Vachharajani AJ, Vachharajani NA, Morris H, Niesen A, Elward A, Linck DA, Mathur AM.

J Perinatol. 2017 Apr;37(4):409-413. doi: 10.1038/jp.2016.243. Epub 2017 Jan 12.


Liver Transplantation for Advanced Hepatocellular Carcinoma after Downstaging Without Up-Front Stage Restrictions.

Chapman WC, Garcia-Aroz S, Vachharajani N, Fowler K, Saad N, Lin Y, Wellen J, Tan B, Khan AS, Doyle MB.

J Am Coll Surg. 2017 Apr;224(4):610-621. doi: 10.1016/j.jamcollsurg.2016.12.020. Epub 2017 Jan 6.


Physician-Patient Communication is Associated With Hepatocellular Carcinoma Screening in Chronic Liver Disease Patients.

Li DJ, Park Y, Vachharajani N, Aung WY, Garonzik-Wang J, Chapman WC.

J Clin Gastroenterol. 2017 May/Jun;51(5):454-460. doi: 10.1097/MCG.0000000000000747.


Liver Resection and Transplantation for Patients With Hepatocellular Carcinoma Beyond Milan Criteria.

Zaydfudim VM, Vachharajani N, Klintmalm GB, Jarnagin WR, Hemming AW, Doyle MB, Cavaness KM, Chapman WC, Nagorney DM.

Ann Surg. 2016 Oct;264(4):650-8. doi: 10.1097/SLA.0000000000001866.


Time-to-Surgery and Survival Outcomes in Resectable Colorectal Liver Metastases: A Multi-Institutional Evaluation.

Leal JN, Bressan AK, Vachharajani N, Gonen M, Kingham TP, D'Angelica MI, Allen PJ, DeMatteo RP, Doyle MB, Bathe OF, Greig PD, Wei A, Chapman WC, Dixon E, Jarnagin WR.

J Am Coll Surg. 2016 May;222(5):766-79. doi: 10.1016/j.jamcollsurg.2016.01.046. Epub 2016 Jan 30.


Results of Simultaneous Liver and Kidney Transplantation: A Single-Center Review.

Doyle MB, Subramanian V, Vachharajani N, Maynard E, Shenoy S, Wellen JR, Lin Y, Chapman WC.

J Am Coll Surg. 2016 Jul;223(1):193-201. doi: 10.1016/j.jamcollsurg.2016.04.005. Epub 2016 Apr 18.


Organ Donor Recovery Performed at an Organ Procurement Organization-Based Facility Is an Effective Way to Minimize Organ Recovery Costs and Increase Organ Yield.

Doyle M, Subramanian V, Vachharajani N, Collins K, Wellen JR, Stahlschmidt E, Brockmeier D, Coleman J, Kappel D, Chapman WC.

J Am Coll Surg. 2016 Apr;222(4):591-600. doi: 10.1016/j.jamcollsurg.2015.12.032. Epub 2016 Feb 29.


Successful use of minimal incision superficialization technique for arteriovenous fistula maturation.

Inkollu S, Wellen J, Beller Z, Zhang T, Vachharajani N, Shenoy S.

J Vasc Surg. 2016 Apr;63(4):1018-25. doi: 10.1016/j.jvs.2015.10.063. Epub 2015 Dec 8.


ABO incompatible renal transplants and decreased likelihood for developing immune responses to HLA and kidney self-antigens.

Subramanian V, Gunasekaran M, Gaut JP, Phelan D, Vachharajani N, Santos RD, Wellen J, Shenoy S, Mohanakumar T.

Hum Immunol. 2016 Jan;77(1):76-83. doi: 10.1016/j.humimm.2015.10.014. Epub 2015 Oct 22.


A quantitative model to predict blood use in adult orthotopic liver transplantation.

Liu C, Vachharajani N, Song S, Cooke R, Kangrga I, Chapman WC, Grossman BJ.

Transfus Apher Sci. 2015 Dec;53(3):386-92. doi: 10.1016/j.transci.2015.07.008. Epub 2015 Aug 10.


Biphenotypic Primary Liver Carcinomas: Assessing Outcomes of Hepatic Directed Therapy.

Fowler K, Saad NE, Brunt E, Doyle MB, Amin M, Vachharajani N, Tan B, Chapman WC.

Ann Surg Oncol. 2015 Dec;22(13):4130-7. doi: 10.1245/s10434-015-4774-y. Epub 2015 Aug 21.


Outcomes Using Grafts from Donors after Cardiac Death.

Doyle MB, Collins K, Vachharajani N, Lowell JA, Shenoy S, Nalbantoglu I, Byrnes K, Garonzik-Wang J, Wellen J, Lin Y, Chapman WC.

J Am Coll Surg. 2015 Jul;221(1):142-52. doi: 10.1016/j.jamcollsurg.2015.03.053. Epub 2015 Apr 8.


Donor Age-Based Analysis of Liver Transplantation Outcomes: Short- and Long-Term Outcomes Are Similar Regardless of Donor Age.

Chapman WC, Vachharajani N, Collins KM, Garonzik-Wang J, Park Y, Wellen JR, Lin Y, Shenoy S, Lowell JA, Doyle MB.

J Am Coll Surg. 2015 Jul;221(1):59-69. doi: 10.1016/j.jamcollsurg.2015.01.061. Epub 2015 Feb 28.


Vascular access creation and maintenance in the USA.

Vachharajani N, Wise P, Klingensmith M, Jaques D, Shenoy S.

J Vasc Access. 2015;16 Suppl 9:S1-4. doi: 10.5301/jva.5000373. Epub 2015 Mar 8. Review.


Surgical treatment of hepatocellular carcinoma in North America: can hepatic resection still be justified?

Chapman WC, Klintmalm G, Hemming A, Vachharajani N, Majella Doyle MB, DeMatteo R, Zaydfudim V, Chung H, Cavaness K, Goldstein R, Zendajas I, Melstrom LG, Nagorney D, Jarnagin W.

J Am Coll Surg. 2015 Apr;220(4):628-37. doi: 10.1016/j.jamcollsurg.2014.12.030. Epub 2015 Jan 6.


Morbid obesity in liver transplant recipients adversely affects longterm graft and patient survival in a single-institution analysis.

Conzen KD, Vachharajani N, Collins KM, Anderson CD, Lin Y, Wellen JR, Shenoy S, Lowell JA, Doyle MB, Chapman WC.

HPB (Oxford). 2015 Mar;17(3):251-7. doi: 10.1111/hpb.12340. Epub 2014 Oct 17.


In vitro metabolism, disposition, preclinical pharmacokinetics and prediction of human pharmacokinetics of DNDI-VL-2098, a potential oral treatment for Visceral Leishmaniasis.

Mukkavilli R, Pinjari J, Patel B, Sengottuvelan S, Mondal S, Gadekar A, Verma M, Patel J, Pothuri L, Chandrashekar G, Koiram P, Harisudhan T, Moinuddin A, Launay D, Vachharajani N, Ramanathan V, Martin D.

Eur J Pharm Sci. 2014 Dec 18;65:147-55. doi: 10.1016/j.ejps.2014.09.006. Epub 2014 Sep 27.


Transcription factor c-Rel plays a crucial role in driving anti-CD40-mediated innate colitis.

Visekruna A, Linnerz T, Martinic V, Vachharajani N, Hartmann S, Harb H, Joeris T, Pfefferle PI, Hofer MJ, Steinhoff U.

Mucosal Immunol. 2015 Mar;8(2):307-15. doi: 10.1038/mi.2014.68. Epub 2014 Aug 6.


Atrial fibrillation in patients undergoing liver transplantation-a single-center experience.

Vannucci A, Rathor R, Vachharajani N, Chapman W, Kangrga I.

Transplant Proc. 2014 Jun;46(5):1432-7. doi: 10.1016/j.transproceed.2014.02.020.


Hepatic venous outflow obstruction in pediatric liver transplantation: technical considerations in prevention, diagnosis, and management.

Sommovilla J, Doyle MM, Vachharajani N, Saad N, Nadler M, Turmelle YP, Weymann A, Chapman WC, Lowell JA.

Pediatr Transplant. 2014 Aug;18(5):497-502. doi: 10.1111/petr.12277. Epub 2014 May 12.


SALL4 immunoreactivity predicts prognosis in Western hepatocellular carcinoma patients but is a rare event: a study of 236 cases.

Liu TC, Vachharajani N, Chapman WC, Brunt EM.

Am J Surg Pathol. 2014 Jul;38(7):966-72. doi: 10.1097/PAS.0000000000000218.


A novel organ donor facility: a decade of experience with liver donors.

Doyle MB, Vachharajani N, Wellen JR, Lowell JA, Shenoy S, Ridolfi G, Jendrisak MD, Coleman J, Maher M, Brockmeier D, Kappel D, Chapman WC.

Am J Transplant. 2014 Mar;14(3):615-20.


Organ allocation in pediatric renal transplants: is there an optimal donor?

Pitt SC, Vachharajani N, Doyle MB, Lowell JA, Chapman WC, Anderson CD, Shenoy S, Wellen JR.

Clin Transplant. 2013 Nov-Dec;27(6):938-44. doi: 10.1111/ctr.12272. Epub 2013 Nov 13.


Noncirrhotic hepatocellular carcinoma: derivation from hepatocellular adenoma? Clinicopathologic analysis.

Liu TC, Vachharajani N, Chapman WC, Brunt EM.

Mod Pathol. 2014 Mar;27(3):420-32. doi: 10.1038/modpathol.2013.148. Epub 2013 Sep 20.


Perioperative blood transfusion affects hepatitis C virus (HCV)-specific immune responses and outcome following liver transplantation in HCV-infected patients.

Subramanian V, Bharat A, Vachharajani N, Crippin J, Shenoy S, Mohanakumar T, Chapman WC.

HPB (Oxford). 2014 Mar;16(3):282-94. doi: 10.1111/hpb.12128. Epub 2013 Jul 22.


Outcomes with split liver transplantation are equivalent to those with whole organ transplantation.

Doyle MB, Maynard E, Lin Y, Vachharajani N, Shenoy S, Anderson C, Earl M, Lowell JA, Chapman WC.

J Am Coll Surg. 2013 Jul;217(1):102-12; discussion 113-4. doi: 10.1016/j.jamcollsurg.2013.03.003. Epub 2013 Apr 30.


Parenchymal alterations in cirrhotic livers in patients with hepatopulmonary syndrome or portopulmonary hypertension.

Ma C, Crippin JS, Chapman WC, Korenblat K, Vachharajani N, Gunter KL, Brunt EM.

Liver Transpl. 2013 Jul;19(7):741-50. doi: 10.1002/lt.23632. Epub 2013 Jun 3.


Liver transplantation for hepatocellular carcinoma: long-term results suggest excellent outcomes.

Doyle MB, Vachharajani N, Maynard E, Shenoy S, Anderson C, Wellen JR, Lowell JA, Chapman WC.

J Am Coll Surg. 2012 Jul;215(1):19-28; discussion 28-30. doi: 10.1016/j.jamcollsurg.2012.02.022. Epub 2012 May 18.


Utilization of hepatitis B core antibody-positive donor liver grafts.

MacConmara MP, Vachharajani N, Wellen JR, Anderson CD, Lowell JA, Shenoy S, Chapman WC, Doyle MB.

HPB (Oxford). 2012 Jan;14(1):42-8. doi: 10.1111/j.1477-2574.2011.00399.x. Epub 2011 Nov 2.


Donor graft steatosis influences immunity to hepatitis C virus and allograft outcome after liver transplantation.

Subramanian V, Seetharam AB, Vachharajani N, Tiriveedhi V, Angaswamy N, Ramachandran S, Crippin JS, Shenoy S, Chapman WC, Mohanakumar T, Anderson CD.

Transplantation. 2011 Dec 15;92(11):1259-68. doi: 10.1097/TP.0b013e318235a1ab.


The effects of age and gender on the pharmacokinetics and pharmacodynamics in healthy subjects of the plasminogen activator, lanoteplase.

Vachharajani NN, Raymond RH, Shyu WC, Stouffer BC, Boulton DW.

Br J Clin Pharmacol. 2011 Nov;72(5):775-86. doi: 10.1111/j.1365-2125.2011.04003.x.

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