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Items: 24


RNA structure drives interaction with proteins.

Sanchez de Groot N, Armaos A, Graña-Montes R, Alriquet M, Calloni G, Vabulas RM, Tartaglia GG.

Nat Commun. 2019 Jul 19;10(1):3246. doi: 10.1038/s41467-019-10923-5.


Assembly of Proteins by Free RNA during the Early Phase of Proteostasis Stress.

Alriquet M, Martínez-Limón A, Hanspach G, Hengesbach M, Tartaglia GG, Calloni G, Vabulas RM.

J Proteome Res. 2019 Jul 5;18(7):2835-2847. doi: 10.1021/acs.jproteome.9b00143. Epub 2019 Jun 18.


Polylysine is a Proteostasis Network-Engaging Structural Determinant.

Lang WH, Calloni G, Vabulas RM.

J Proteome Res. 2018 May 4;17(5):1967-1977. doi: 10.1021/acs.jproteome.8b00108. Epub 2018 Apr 25.


CHIP as a membrane-shuttling proteostasis sensor.

Kopp Y, Lang WH, Schuster TB, Martínez-Limón A, Hofbauer HF, Ernst R, Calloni G, Vabulas RM.

Elife. 2017 Nov 1;6. pii: e29388. doi: 10.7554/eLife.29388.


Recognition of enzymes lacking bound cofactor by protein quality control.

Martínez-Limón A, Alriquet M, Lang WH, Calloni G, Wittig I, Vabulas RM.

Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):12156-12161. Epub 2016 Oct 12.


Quantitative proteomics reveals that Hsp90 inhibition preferentially targets kinases and the DNA damage response.

Sharma K, Vabulas RM, Macek B, Pinkert S, Cox J, Mann M, Hartl FU.

Mol Cell Proteomics. 2012 Mar;11(3):M111.014654. doi: 10.1074/mcp.M111.014654. Epub 2011 Dec 13.


Aberrant protein interactions in amyloid disease.

Vabulas RM, Hartl FU.

Cell Cycle. 2011 May 15;10(10):1512-3. Epub 2011 May 15.


The cellular prion protein mediates neurotoxic signalling of β-sheet-rich conformers independent of prion replication.

Resenberger UK, Harmeier A, Woerner AC, Goodman JL, Müller V, Krishnan R, Vabulas RM, Kretzschmar HA, Lindquist S, Hartl FU, Multhaup G, Winklhofer KF, Tatzelt J.

EMBO J. 2011 May 18;30(10):2057-70. doi: 10.1038/emboj.2011.86. Epub 2011 Mar 25.


Amyloid-like aggregates sequester numerous metastable proteins with essential cellular functions.

Olzscha H, Schermann SM, Woerner AC, Pinkert S, Hecht MH, Tartaglia GG, Vendruscolo M, Hayer-Hartl M, Hartl FU, Vabulas RM.

Cell. 2011 Jan 7;144(1):67-78. doi: 10.1016/j.cell.2010.11.050.


Protein folding in the cytoplasm and the heat shock response.

Vabulas RM, Raychaudhuri S, Hayer-Hartl M, Hartl FU.

Cold Spring Harb Perspect Biol. 2010 Dec;2(12):a004390. doi: 10.1101/cshperspect.a004390. Review.


Proteasome function and protein biosynthesis.

Vabulas RM.

Curr Opin Clin Nutr Metab Care. 2007 Jan;10(1):24-31. Review.


A balance of protein synthesis and proteasome-dependent degradation determines the maintenance of LTP.

Fonseca R, Vabulas RM, Hartl FU, Bonhoeffer T, Nägerl UV.

Neuron. 2006 Oct 19;52(2):239-45.


Protein synthesis upon acute nutrient restriction relies on proteasome function.

Vabulas RM, Hartl FU.

Science. 2005 Dec 23;310(5756):1960-3.


Heat shock proteins as ligands of toll-like receptors.

Vabulas RM, Wagner H, Schild H.

Curr Top Microbiol Immunol. 2002;270:169-84. Review.


Cutting edge: myeloid differentiation factor 88 deficiency improves resistance against sepsis caused by polymicrobial infection.

Weighardt H, Kaiser-Moore S, Vabulas RM, Kirschning CJ, Wagner H, Holzmann B.

J Immunol. 2002 Sep 15;169(6):2823-7.


CpG-DNA aided cross-presentation of soluble antigens by dendritic cells.

Maurer T, Heit A, Hochrein H, Ampenberger F, O'Keeffe M, Bauer S, Lipford GB, Vabulas RM, Wagner H.

Eur J Immunol. 2002 Aug;32(8):2356-64.


Bacterial CpG-DNA and lipopolysaccharides activate Toll-like receptors at distinct cellular compartments.

Ahmad-Nejad P, Häcker H, Rutz M, Bauer S, Vabulas RM, Wagner H.

Eur J Immunol. 2002 Jul;32(7):1958-68.


The endoplasmic reticulum-resident heat shock protein Gp96 activates dendritic cells via the Toll-like receptor 2/4 pathway.

Vabulas RM, Braedel S, Hilf N, Singh-Jasuja H, Herter S, Ahmad-Nejad P, Kirschning CJ, Da Costa C, Rammensee HG, Wagner H, Schild H.

J Biol Chem. 2002 Jun 7;277(23):20847-53. Epub 2002 Mar 23.


HSP70 as endogenous stimulus of the Toll/interleukin-1 receptor signal pathway.

Vabulas RM, Ahmad-Nejad P, Ghose S, Kirschning CJ, Issels RD, Wagner H.

J Biol Chem. 2002 Apr 26;277(17):15107-12. Epub 2002 Feb 12.


Endocytosed HSP60s use toll-like receptor 2 (TLR2) and TLR4 to activate the toll/interleukin-1 receptor signaling pathway in innate immune cells.

Vabulas RM, Ahmad-Nejad P, da Costa C, Miethke T, Kirschning CJ, Häcker H, Wagner H.

J Biol Chem. 2001 Aug 17;276(33):31332-9. Epub 2001 Jun 11.


Bacterial CpG-DNA activates dendritic cells in vivo: T helper cell-independent cytotoxic T cell responses to soluble proteins.

Sparwasser T, Vabulas RM, Villmow B, Lipford GB, Wagner H.

Eur J Immunol. 2000 Dec;30(12):3591-7.


CpG-DNA activates in vivo T cell epitope presenting dendritic cells to trigger protective antiviral cytotoxic T cell responses.

Vabulas RM, Pircher H, Lipford GB, Häcker H, Wagner H.

J Immunol. 2000 Mar 1;164(5):2372-8.


Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells.

Sparwasser T, Koch ES, Vabulas RM, Heeg K, Lipford GB, Ellwart JW, Wagner H.

Eur J Immunol. 1998 Jun;28(6):2045-54.

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