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Items: 1 to 50 of 283

1.

Alendronate-induced disruption of actin cytoskeleton and inhibition of migration/invasion are associated with cofilin downregulation in PC-3 prostate cancer cells.

Virtanen SS, Ishizu T, Sandholm JA, Löyttyniemi E, Väänänen HK, Tuomela JM, Härkönen PL.

Oncotarget. 2018 Aug 24;9(66):32593-32608. doi: 10.18632/oncotarget.25961. eCollection 2018 Aug 24.

2.

Fibrosis and wall thickness affect ventricular repolarization dynamics in hypertrophic cardiomyopathy.

Jalanko M, Väänänen H, Tarkiainen M, Sipola P, Jääskeläinen P, Lauerma K, Laitinen T, Laitinen T, Laine M, Heliö T, Kuusisto J, Viitasalo M.

Ann Noninvasive Electrocardiol. 2018 Nov;23(6):e12582. doi: 10.1111/anec.12582. Epub 2018 Jul 4.

PMID:
29974557
3.

Peak CK-MB has a strong association with chronic scar size and wall motion abnormalities after revascularized non-transmural myocardial infarction - a prospective CMR study.

Pöyhönen P, Kylmälä M, Vesterinen P, Kivistö S, Holmström M, Lauerma K, Väänänen H, Toivonen L, Hänninen H.

BMC Cardiovasc Disord. 2018 Feb 8;18(1):27. doi: 10.1186/s12872-018-0767-7.

4.

Role of fibroblast growth factor receptors (FGFR) and FGFR like-1 (FGFRL1) in mesenchymal stromal cell differentiation to osteoblasts and adipocytes.

Kähkönen TE, Ivaska KK, Jiang M, Büki KG, Väänänen HK, Härkönen PL.

Mol Cell Endocrinol. 2018 Feb 5;461:194-204. doi: 10.1016/j.mce.2017.09.015. Epub 2017 Sep 18.

PMID:
28923346
5.

Vasomotor hot flashes and cardiac repolarization: a randomized placebo-controlled trial of postmenopausal hormone therapy.

Lantto H, Haapalahti P, Viitasalo M, Väänänen H, Sovijärvi ARA, Ylikorkala O, Mikkola TS.

Menopause. 2017 Dec;24(12):1386-1391. doi: 10.1097/GME.0000000000000932.

PMID:
28697043
6.

Slowed depolarization and irregular repolarization in catecholaminergic polymorphic ventricular tachycardia: a study from cellular Ca2+ transients and action potentials to clinical monophasic action potentials and electrocardiography.

Paavola J, Väänänen H, Larsson K, Penttinen K, Toivonen L, Kontula K, Laine M, Aalto-Setälä K, Swan H, Viitasalo M.

Europace. 2016 Oct;18(10):1599-1607. Epub 2015 Dec 24.

PMID:
26705554
7.

Cardiac repolarization in recently postmenopausal women with or without hot flushes.

Lantto H, Mikkola TS, Tuomikoski P, Viitasalo M, Väänänen H, Sovijärvi AR, Haapalahti P.

Menopause. 2016 May;23(5):528-34. doi: 10.1097/GME.0000000000000564.

PMID:
26599687
8.

The effects of acute hyperinsulinemia on bone metabolism.

Ivaska KK, Heliövaara MK, Ebeling P, Bucci M, Huovinen V, Väänänen HK, Nuutila P, Koistinen HA.

Endocr Connect. 2015 Sep;4(3):155-62. doi: 10.1530/EC-15-0022. Epub 2015 Jun 5.

9.

Sensitivity and specificity of automated detection of early repolarization in standard 12-lead electrocardiography.

Kenttä T, Porthan K, Tikkanen JT, Väänänen H, Oikarinen L, Viitasalo M, Karanko H, Laaksonen M, Huikuri HV.

Ann Noninvasive Electrocardiol. 2015 Jul;20(4):355-61. doi: 10.1111/anec.12226. Epub 2014 Nov 4.

PMID:
25367676
10.

Assessment of myocardial infarct size with body surface potential mapping: validation against contrast-enhanced cardiac magnetic resonance imaging.

Kylmälä MM, Konttila T, Vesterinen P, Kivistö SM, Lauerma K, Lindholm M, Väänänen H, Stenroos M, Nieminen MS, Hänninen H, Toivonen L.

Ann Noninvasive Electrocardiol. 2015 May;20(3):240-52. doi: 10.1111/anec.12198. Epub 2014 Sep 18.

PMID:
25234825
11.

U wave features in body surface potential mapping in post-myocardial infarction patients.

Wang B, Korhonen P, Tierala I, Hänninen H, Väänänen H, Toivonen L.

Ann Noninvasive Electrocardiol. 2013 Nov;18(6):538-46. doi: 10.1111/anec.12071. Epub 2013 Jul 30.

PMID:
24303968
12.

Novel perspectives on the transcytotic route in osteoclasts.

Hirvonen MJ, Fagerlund K, Lakkakorpi P, Väänänen HK, Mulari MT.

Bonekey Rep. 2013 Mar 13;2:306. doi: 10.1038/bonekey.2013.40. eCollection 2013.

13.

Predictive value of electrocardiographic T-wave morphology parameters and T-wave peak to T-wave end interval for sudden cardiac death in the general population.

Porthan K, Viitasalo M, Toivonen L, Havulinna AS, Jula A, Tikkanen JT, Väänänen H, Nieminen MS, Huikuri HV, Newton-Cheh C, Salomaa V, Oikarinen L.

Circ Arrhythm Electrophysiol. 2013 Aug;6(4):690-6. doi: 10.1161/CIRCEP.113.000356. Epub 2013 Jul 23.

PMID:
23881778
14.

Predicting recovery of myocardial function by electrocardiography after acute infarction.

Kylmälä MM, Konttila T, Vesterinen P, Lindholm M, Väänänen H, Stenroos M, Nieminen MS, Hänninen H, Toivonen L.

Ann Noninvasive Electrocardiol. 2013 May;18(3):230-9. doi: 10.1111/anec.12015. Epub 2012 Nov 22.

PMID:
23714081
15.

The effectiveness of teriparatide in the clinical practice--attenuation of the bone mineral density outcome by increasing age and bisphosphonate pretreatment.

Koski AM, Löyttyniemi E, Väänänen H, Laine H, Niskanen L, Nevalainen PI, Korpi-Hyövälti E, Välimäki MJ.

Ann Med. 2013 May;45(3):230-5. doi: 10.3109/07853890.2012.742560. Epub 2013 Jan 20.

PMID:
23330730
16.

Serum osteocalcin is not associated with glucose but is inversely associated with leptin across generations of nondiabetic women.

Lu C, Ivaska KK, Alen M, Wang Q, Törmäkangas T, Xu L, Wiklund P, Mikkola TM, Pekkala S, Tian H, Väänänen HK, Cheng S.

J Clin Endocrinol Metab. 2012 Nov;97(11):4106-14. doi: 10.1210/jc.2012-2045. Epub 2012 Sep 4.

PMID:
22948754
17.

Rab13 is upregulated during osteoclast differentiation and associates with small vesicles revealing polarized distribution in resorbing cells.

Hirvonen MJ, Mulari MT, Büki KG, Vihko P, Härkönen PL, Väänänen HK.

J Histochem Cytochem. 2012 Jul;60(7):537-49. doi: 10.1369/0022155412448069. Epub 2012 May 4.

18.

Transient 100 nM dexamethasone treatment reduces inter- and intraindividual variations in osteoblastic differentiation of bone marrow-derived human mesenchymal stem cells.

Alm JJ, Heino TJ, Hentunen TA, Väänänen HK, Aro HT.

Tissue Eng Part C Methods. 2012 Sep;18(9):658-66. doi: 10.1089/ten.TEC.2011.0675. Epub 2012 May 14.

PMID:
22428545
19.

Urinary osteocalcin and serum pro-C-type natriuretic peptide predict linear catch-up growth in infants.

Kilpeläinen L, Ivaska KK, Kuiri-Hänninen T, Väänänen HK, Rehfeld JF, Goetze JP, Sankilampi U, Dunkel L.

J Bone Miner Res. 2012 Jul;27(7):1528-35. doi: 10.1002/jbmr.1596.

20.

The effect of oral glucose tolerance test on serum osteocalcin and bone turnover markers in young adults.

Paldánius PM, Ivaska KK, Hovi P, Andersson S, Väänänen HK, Kajantie E, Mäkitie O.

Calcif Tissue Int. 2012 Feb;90(2):90-5. doi: 10.1007/s00223-011-9551-8. Epub 2011 Dec 8.

PMID:
22147278
21.

Vasomotor hot flashes and heart rate variability: a placebo-controlled trial of postmenopausal hormone therapy.

Lantto H, Haapalahti P, Tuomikoski P, Viitasalo M, Väänänen H, Sovijärvi AR, Ylikorkala O, Mikkola TS.

Menopause. 2012 Jan;19(1):82-8. doi: 10.1097/gme.0b013e318221bae8.

PMID:
21934534
22.

The early repolarization pattern in the general population: clinical correlates and heritability.

Noseworthy PA, Tikkanen JT, Porthan K, Oikarinen L, Pietilä A, Harald K, Peloso GM, Merchant FM, Jula A, Väänänen H, Hwang SJ, O'Donnell CJ, Salomaa V, Newton-Cheh C, Huikuri HV.

J Am Coll Cardiol. 2011 May 31;57(22):2284-9. doi: 10.1016/j.jacc.2011.04.003.

23.

Receptor tyrosine kinase inhibition causes simultaneous bone loss and excess bone formation within growing bone in rats.

Nurmio M, Joki H, Kallio J, Määttä JA, Väänänen HK, Toppari J, Jahnukainen K, Laitala-Leinonen T.

Toxicol Appl Pharmacol. 2011 Aug 1;254(3):267-79. doi: 10.1016/j.taap.2011.04.019. Epub 2011 May 4.

PMID:
21586300
24.

Epinephrine bolus test in detecting long QT syndrome mutation carriers with indeterminable electrocardiographic phenotype.

Hekkala AM, Swan H, Viitasalo M, Väänänen H, Toivonen L.

Ann Noninvasive Electrocardiol. 2011 Apr;16(2):172-9. doi: 10.1111/j.1542-474X.2011.00426.x.

PMID:
21496168
25.

The critical role of IL-34 in osteoclastogenesis.

Chen Z, Buki K, Vääräniemi J, Gu G, Väänänen HK.

PLoS One. 2011 Apr 8;6(4):e18689. doi: 10.1371/journal.pone.0018689.

26.

Comparison of QT peak and QT end interval responses to autonomic adaptation in asymptomatic LQT1 mutation carriers.

Haapalahti P, Viitasalo M, Perhonen M, Väänänen H, Mäkijärvi M, Swan H, Toivonen L.

Clin Physiol Funct Imaging. 2011 May;31(3):209-14. doi: 10.1111/j.1475-097X.2010.01002.x. Epub 2010 Dec 7.

27.

Dynamic QT/RR relationship in post-myocardial infarction patients with and without cardiac arrest.

Järvenpää J, Oikarinen L, Korhonen P, Väänänen H, Toivonen L, Viitasalo M.

Scand Cardiovasc J. 2010 Dec;44(6):352-8. doi: 10.3109/14017431.2010.490950. Epub 2010 Nov 11.

PMID:
21070120
28.

Imbalance of the autonomic nervous system at night in women with gestational diabetes.

Pöyhönen-Alho M, Viitasalo M, Nicholls MG, Lindström BM, Väänänen H, Kaaja R.

Diabet Med. 2010 Sep;27(9):988-94. doi: 10.1111/j.1464-5491.2010.03062.x.

PMID:
20722671
29.

A rationale for osteoclast selectivity of inhibiting the lysosomal V-ATPase a3 isoform.

Nyman JK, Väänänen HK.

Calcif Tissue Int. 2010 Sep;87(3):273-83. doi: 10.1007/s00223-010-9395-7. Epub 2010 Jul 2.

PMID:
20596699
30.

Abnormal repolarization dynamics revealed in exercise test in long QT syndrome mutation carriers with normal resting QT interval.

Hekkala AM, Viitasalo M, Väänänen H, Swan H, Toivonen L.

Europace. 2010 Sep;12(9):1296-301. doi: 10.1093/europace/euq184. Epub 2010 Jun 20.

PMID:
20566482
31.

Fragmented QRS in prediction of cardiac deaths and heart failure hospitalizations after myocardial infarction.

Korhonen P, Husa T, Konttila T, Tierala I, Mäkijärvi M, Väänänen H, Ojanen J, Vehtari A, Toivonen L.

Ann Noninvasive Electrocardiol. 2010 Apr;15(2):130-7. doi: 10.1111/j.1542-474X.2010.00353.x.

PMID:
20522053
32.

Relationship of common candidate gene variants to electrocardiographic T-wave peak to T-wave end interval and T-wave morphology parameters.

Porthan K, Marjamaa A, Viitasalo M, Väänänen H, Jula A, Toivonen L, Nieminen MS, Newton-Cheh C, Salomaa V, Kontula K, Oikarinen L.

Heart Rhythm. 2010 Jul;7(7):898-903. doi: 10.1016/j.hrthm.2010.03.002. Epub 2010 Mar 4.

33.

Degradation of hydroxyapatite in vivo and in vitro requires osteoclastic sodium-bicarbonate co-transporter NBCn1.

Riihonen R, Nielsen S, Väänänen HK, Laitala-Leinonen T, Kwon TH.

Matrix Biol. 2010 May;29(4):287-94. doi: 10.1016/j.matbio.2010.01.003. Epub 2010 Jan 15.

PMID:
20079835
34.

Association between vasomotor hot flashes and heart rate variability in recently postmenopausal women.

Hoikkala H, Haapalahti P, Viitasalo M, Väänänen H, Sovijärvi AR, Ylikorkala O, Mikkola TS.

Menopause. 2010 Mar;17(2):315-20. doi: 10.1097/gme.0b013e3181c2bb6d.

PMID:
20009960
35.

Bone turnover markers and prediction of fracture: a prospective follow-up study of 1040 elderly women for a mean of 9 years.

Ivaska KK, Gerdhem P, Väänänen HK, Akesson K, Obrant KJ.

J Bone Miner Res. 2010 Feb;25(2):393-403. doi: 10.1359/jbmr.091006.

36.

Overexpression of vascular endothelial growth factor C increases growth and alters the metastatic pattern of orthotopic PC-3 prostate tumors.

Tuomela J, Valta M, Seppänen J, Tarkkonen K, Väänänen HK, Härkönen P.

BMC Cancer. 2009 Oct 12;9:362. doi: 10.1186/1471-2407-9-362.

37.

Predictive value of electrocardiographic QT interval and T-wave morphology parameters for all-cause and cardiovascular mortality in a general population sample.

Porthan K, Viitasalo M, Jula A, Reunanen A, Rapola J, Väänänen H, Nieminen MS, Toivonen L, Salomaa V, Oikarinen L.

Heart Rhythm. 2009 Aug;6(8):1202-8, 1208.e1. doi: 10.1016/j.hrthm.2009.05.006. Epub 2009 May 8.

PMID:
19632634
38.

Evidence for the role of osteocytes in the initiation of targeted remodeling.

Heino TJ, Kurata K, Higaki H, Väänänen HK.

Technol Health Care. 2009;17(1):49-56. doi: 10.3233/THC-2009-0534.

PMID:
19478405
39.

Osteocyte-derived HB-GAM (pleiotrophin) is associated with bone formation and mechanical loading.

Imai S, Heino TJ, Hienola A, Kurata K, Büki K, Matsusue Y, Väänänen HK, Rauvala H.

Bone. 2009 May;44(5):785-94. doi: 10.1016/j.bone.2009.01.004. Epub 2009 Jan 15.

PMID:
19442624
40.

FGF-8b induces growth and rich vascularization in an orthotopic PC-3 model of prostate cancer.

Valta MP, Tuomela J, Vuorikoski H, Loponen N, Väänänen RM, Pettersson K, Väänänen HK, Härkönen PL.

J Cell Biochem. 2009 Jul 1;107(4):769-84. doi: 10.1002/jcb.22175.

PMID:
19415685
41.

Complex T-wave morphology in body surface potential mapping in prediction of arrhythmic events in patients with acute myocardial infarction and cardiac dysfunction.

Korhonen P, Husa T, Konttila T, Tierala I, Mäkijärvi M, Väänänen H, Toivonen L.

Europace. 2009 Apr;11(4):514-20. doi: 10.1093/europace/eup051. Epub 2009 Mar 11.

PMID:
19279023
42.

Effect of impact exercise on bone metabolism.

Vainionpää A, Korpelainen R, Väänänen HK, Haapalahti J, Jämsä T, Leppäluoto J.

Osteoporos Int. 2009 Oct;20(10):1725-33. doi: 10.1007/s00198-009-0881-6. Epub 2009 Mar 5.

PMID:
19262975
43.

Reversal of atrial remodeling after cardioversion of persistent atrial fibrillation measured with magnetocardiography.

Lehto M, Jurkko R, Parikka H, Mäntynen V, Väänänen H, Montonen J, Voipio-Pulkki LM, Toivonen L, Laine M.

Pacing Clin Electrophysiol. 2009 Feb;32(2):217-23. doi: 10.1111/j.1540-8159.2008.02205.x.

PMID:
19170911
44.

High prevalence of four long QT syndrome founder mutations in the Finnish population.

Marjamaa A, Salomaa V, Newton-Cheh C, Porthan K, Reunanen A, Karanko H, Jula A, Lahermo P, Väänänen H, Toivonen L, Swan H, Viitasalo M, Nieminen MS, Peltonen L, Oikarinen L, Palotie A, Kontula K.

Ann Med. 2009;41(3):234-40. doi: 10.1080/07853890802668530.

45.

Overexpression of cathepsin K accelerates the resorption cycle and osteoblast differentiation in vitro.

Morko J, Kiviranta R, Mulari MT, Ivaska KK, Väänänen HK, Vuorio E, Laitala-Leinonen T.

Bone. 2009 Apr;44(4):717-28. doi: 10.1016/j.bone.2008.11.019. Epub 2008 Dec 11.

PMID:
19118660
46.

Can elevated serum TRACP-5b levels predict stress fractures? A cohort study.

Ruohola JP, Mulari M, Haataja RI, Väänänen HK, Pihlajamäki HK.

Scand J Surg. 2009;98(4):239-43.

PMID:
20218422
47.

Clinical performance of six different serum tartrate-resistant acid phosphatase assays for monitoring alendronate treatment.

Fagerlund KM, Janckila AJ, Ylipahkala H, Tiitinen SL, Nenonen A, Cheng S, Uusi-Rasi K, Yam LT, Väänänen HK, Halleen JM.

Clin Lab. 2008;54(9-10):347-54.

PMID:
19097492
48.

Non-invasive detection of conduction pathways to left atrium using magnetocardiography: validation by intra-cardiac electroanatomic mapping.

Jurkko R, Mäntynen V, Tapanainen JM, Montonen J, Väänänen H, Parikka H, Toivonen L.

Europace. 2009 Feb;11(2):169-77. doi: 10.1093/europace/eun335. Epub 2008 Dec 13.

PMID:
19074785
49.

Common candidate gene variants are associated with QT interval duration in the general population.

Marjamaa A, Newton-Cheh C, Porthan K, Reunanen A, Lahermo P, Väänänen H, Jula A, Karanko H, Swan H, Toivonen L, Nieminen MS, Viitasalo M, Peltonen L, Oikarinen L, Palotie A, Kontula K, Salomaa V.

J Intern Med. 2009 Apr;265(4):448-58. doi: 10.1111/j.1365-2796.2008.02026.x. Epub 2009 Oct 25.

50.

Improved methods for testing antiresorptive compounds in human osteoclast cultures.

Rissanen JP, Ylipahkala H, Fagerlund KM, Long C, Väänänen HK, Halleen JM.

J Bone Miner Metab. 2009;27(1):105-9. doi: 10.1007/s00774-008-0002-1. Epub 2008 Nov 19.

PMID:
19018457

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