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Items: 19

1.

Lymphatic exosomes promote dendritic cell migration along guidance cues.

Brown M, Johnson LA, Leone DA, Majek P, Vaahtomeri K, Senfter D, Bukosza N, Schachner H, Asfour G, Langer B, Hauschild R, Parapatics K, Hong YK, Bennett KL, Kain R, Detmar M, Sixt M, Jackson DG, Kerjaschki D.

J Cell Biol. 2018 Jun 4;217(6):2205-2221. doi: 10.1083/jcb.201612051. Epub 2018 Apr 12.

2.

Stromal Lkb1 deficiency leads to gastrointestinal tumorigenesis involving the IL-11-JAK/STAT3 pathway.

Ollila S, Domènech-Moreno E, Laajanen K, Wong IP, Tripathi S, Pentinmikko N, Gao Y, Yan Y, Niemelä EH, Wang TC, Viollet B, Leone G, Katajisto P, Vaahtomeri K, Mäkelä TP.

J Clin Invest. 2018 Jan 2;128(1):402-414. doi: 10.1172/JCI93597. Epub 2017 Dec 4.

3.

Lymphangiogenesis guidance by paracrine and pericellular factors.

Vaahtomeri K, Karaman S, Mäkinen T, Alitalo K.

Genes Dev. 2017 Aug 15;31(16):1615-1634. doi: 10.1101/gad.303776.117. Review.

4.

Locally Triggered Release of the Chemokine CCL21 Promotes Dendritic Cell Transmigration across Lymphatic Endothelia.

Vaahtomeri K, Brown M, Hauschild R, De Vries I, Leithner AF, Mehling M, Kaufmann WA, Sixt M.

Cell Rep. 2017 May 2;19(5):902-909. doi: 10.1016/j.celrep.2017.04.027.

5.

Dendritic Cells Interpret Haptotactic Chemokine Gradients in a Manner Governed by Signal-to-Noise Ratio and Dependent on GRK6.

Schwarz J, Bierbaum V, Vaahtomeri K, Hauschild R, Brown M, de Vries I, Leithner A, Reversat A, Merrin J, Tarrant T, Bollenbach T, Sixt M.

Curr Biol. 2017 May 8;27(9):1314-1325. doi: 10.1016/j.cub.2017.04.004. Epub 2017 Apr 27.

6.

Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions.

Martins R, Maier J, Gorki AD, Huber KV, Sharif O, Starkl P, Saluzzo S, Quattrone F, Gawish R, Lakovits K, Aichinger MC, Radic-Sarikas B, Lardeau CH, Hladik A, Korosec A, Brown M, Vaahtomeri K, Duggan M, Kerjaschki D, Esterbauer H, Colinge J, Eisenbarth SC, Decker T, Bennett KL, Kubicek S, Sixt M, Superti-Furga G, Knapp S.

Nat Immunol. 2016 Dec;17(12):1361-1372. doi: 10.1038/ni.3590. Epub 2016 Oct 31.

PMID:
27798618
7.

Intralymphatic CCL21 Promotes Tissue Egress of Dendritic Cells through Afferent Lymphatic Vessels.

Russo E, Teijeira A, Vaahtomeri K, Willrodt AH, Bloch JS, Nitschké M, Santambrogio L, Kerjaschki D, Sixt M, Halin C.

Cell Rep. 2016 Feb 23;14(7):1723-1734. doi: 10.1016/j.celrep.2016.01.048. Epub 2016 Feb 11.

8.

SUMOylation of AMPKα1 by PIAS4 specifically regulates mTORC1 signalling.

Yan Y, Ollila S, Wong IPL, Vallenius T, Palvimo JJ, Vaahtomeri K, Mäkelä TP.

Nat Commun. 2015 Nov 30;6:8979. doi: 10.1038/ncomms9979.

9.

Physiology: Relax and come in.

Vaahtomeri K, Sixt M.

Nature. 2014 Oct 23;514(7523):441-2. doi: 10.1038/514441a. No abstract available.

PMID:
25341781
10.

An association between NUAK2 and MRIP reveals a novel mechanism for regulation of actin stress fibers.

Vallenius T, Vaahtomeri K, Kovac B, Osiceanu AM, Viljanen M, Mäkelä TP.

J Cell Sci. 2011 Feb 1;124(Pt 3):384-93. doi: 10.1242/jcs.072660.

11.

Molecular mechanisms of tumor suppression by LKB1.

Vaahtomeri K, Mäkelä TP.

FEBS Lett. 2011 Apr 6;585(7):944-51. doi: 10.1016/j.febslet.2010.12.034. Epub 2010 Dec 27. Review.

12.

Non-CDK-bound p27 (p27(NCDK)) is a marker for cell stress and is regulated through the Akt/PKB and AMPK-kinase pathways.

Björklund MA, Vaahtomeri K, Peltonen K, Viollet B, Mäkelä TP, Band AM, Laiho M.

Exp Cell Res. 2010 Mar 10;316(5):762-74. doi: 10.1016/j.yexcr.2009.12.014. Epub 2009 Dec 28.

PMID:
20036235
13.

PKA phosphorylates and inactivates AMPKalpha to promote efficient lipolysis.

Djouder N, Tuerk RD, Suter M, Salvioni P, Thali RF, Scholz R, Vaahtomeri K, Auchli Y, Rechsteiner H, Brunisholz RA, Viollet B, Mäkelä TP, Wallimann T, Neumann D, Krek W.

EMBO J. 2010 Jan 20;29(2):469-81. doi: 10.1038/emboj.2009.339. Epub 2009 Nov 26.

14.

Lkb1 is required for TGFbeta-mediated myofibroblast differentiation.

Vaahtomeri K, Ventelä E, Laajanen K, Katajisto P, Wipff PJ, Hinz B, Vallenius T, Tiainen M, Mäkelä TP.

J Cell Sci. 2008 Nov 1;121(Pt 21):3531-40. doi: 10.1242/jcs.032706. Epub 2008 Oct 7.

15.

LKB1 in endothelial cells is required for angiogenesis and TGFbeta-mediated vascular smooth muscle cell recruitment.

Londesborough A, Vaahtomeri K, Tiainen M, Katajisto P, Ekman N, Vallenius T, Mäkelä TP.

Development. 2008 Jul;135(13):2331-8. doi: 10.1242/dev.017038.

16.

LKB1 signaling in mesenchymal cells required for suppression of gastrointestinal polyposis.

Katajisto P, Vaahtomeri K, Ekman N, Ventelä E, Ristimäki A, Bardeesy N, Feil R, DePinho RA, Mäkelä TP.

Nat Genet. 2008 Apr;40(4):455-9. doi: 10.1038/ng.98. Epub 2008 Mar 2.

PMID:
18311138
17.

The LKB1 tumor suppressor kinase in human disease.

Katajisto P, Vallenius T, Vaahtomeri K, Ekman N, Udd L, Tiainen M, Mäkelä TP.

Biochim Biophys Acta. 2007 Jan;1775(1):63-75. Epub 2006 Aug 16. Review.

PMID:
17010524
18.

[A surprising link between the tumor suppressor gene and regulation of metabolism].

Vaahtomeri K, Udd L, Tiainen M.

Duodecim. 2004;120(11):1297-8. Finnish. No abstract available.

PMID:
15327080
19.

Growth arrest by the LKB1 tumor suppressor: induction of p21(WAF1/CIP1).

Tiainen M, Vaahtomeri K, Ylikorkala A, Mäkelä TP.

Hum Mol Genet. 2002 Jun 15;11(13):1497-504.

PMID:
12045203

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