Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 375


Gestational diabetes and maternal obesity are associated with epigenome-wide methylation changes in children.

Hjort L, Martino D, Grunnet LG, Naeem H, Maksimovic J, Olsson AH, Zhang C, Ling C, Olsen SF, Saffery R, Vaag AA.

JCI Insight. 2018 Sep 6;3(17). pii: 122572. doi: 10.1172/jci.insight.122572. [Epub ahead of print]


Association between genetic risk variants and glucose intolerance during pregnancy in north Indian women.

Arora GP, Almgren P, Brøns C, Thaman RG, Vaag AA, Groop L, Prasad RB.

BMC Med Genomics. 2018 Aug 8;11(1):64. doi: 10.1186/s12920-018-0380-8.


Genetic variants of gestational diabetes mellitus: a study of 112 SNPs among 8722 women in two independent populations.

Ding M, Chavarro J, Olsen S, Lin Y, Ley SH, Bao W, Rawal S, Grunnet LG, Thuesen ACB, Mills JL, Yeung E, Hinkle SN, Zhang W, Vaag A, Liu A, Hu FB, Zhang C.

Diabetologia. 2018 Aug;61(8):1758-1768. doi: 10.1007/s00125-018-4637-8. Epub 2018 Jun 12.


Gestational Diabetes Mellitus and Renal Function: A Prospective Study With 9- to 16-Year Follow-up After Pregnancy.

Rawal S, Olsen SF, Grunnet LG, Ma RC, Hinkle SN, Granström C, Wu J, Yeung E, Mills JL, Zhu Y, Bao W, Ley SH, Hu FB, Damm P, Vaag A, Tsai MY, Zhang C.

Diabetes Care. 2018 Jul;41(7):1378-1384. doi: 10.2337/dc17-2629. Epub 2018 May 4.


Danish Centre for Strategic Research in Type 2 Diabetes (DD2) project cohort of newly diagnosed patients with type 2 diabetes: a cohort profile.

Christensen DH, Nicolaisen SK, Berencsi K, Beck-Nielsen H, Rungby J, Friborg S, Brandslund I, Christiansen JS, Vaag A, Sørensen HT, Nielsen JS, Thomsen RW.

BMJ Open. 2018 Apr 7;8(4):e017273. doi: 10.1136/bmjopen-2017-017273.


Increased expression of microRNA-15a and microRNA-15b in skeletal muscle from adult offspring of women with diabetes in pregnancy.

Houshmand-Oeregaard A, Schrölkamp M, Kelstrup L, Hansen NS, Hjort L, Thuesen ACB, Broholm C, Mathiesen ER, Clausen TD, Vaag A, Damm P.

Hum Mol Genet. 2018 May 15;27(10):1763-1771. doi: 10.1093/hmg/ddy085.


Plasma ceramide levels are altered in low and normal birth weight men in response to short-term high-fat overfeeding.

Ribel-Madsen A, Ribel-Madsen R, Nielsen KF, Brix S, Vaag AA, Brøns C.

Sci Rep. 2018 Feb 22;8(1):3452. doi: 10.1038/s41598-018-21419-5.


N1-methylnicotinamide is a signalling molecule produced in skeletal muscle coordinating energy metabolism.

Ström K, Morales-Alamo D, Ottosson F, Edlund A, Hjort L, Jörgensen SW, Almgren P, Zhou Y, Martin-Rincon M, Ekman C, Pérez-López A, Ekström O, Perez-Suarez I, Mattiasson M, de Pablos-Velasco P, Oskolkov N, Ahlqvist E, Wierup N, Eliasson L, Vaag A, Groop L, Stenkula KG, Fernandez C, Calbet JAL, Holmberg HC, Hansson O.

Sci Rep. 2018 Feb 14;8(1):3016. doi: 10.1038/s41598-018-21099-1.


Perspectives on diabetes mortality as the result of residual confounding and reverse causality by common disease.

Thuesen ACB, Vaag A.

Diabetes Obes Metab. 2018 Jun;20(6):1342-1349. doi: 10.1111/dom.13238. Epub 2018 Feb 25. Review.


MECHANISMS IN ENDOCRINOLOGY: SGLT2 inhibitors: clinical benefits by restoration of normal diurnal metabolism?

Esterline RL, Vaag A, Oscarsson J, Vora J.

Eur J Endocrinol. 2018 Apr;178(4):R113-R125. doi: 10.1530/EJE-17-0832. Epub 2018 Jan 25. Review.


Telomere length is reduced in 9- to 16-year-old girls exposed to gestational diabetes in utero.

Hjort L, Vryer R, Grunnet LG, Burgner D, Olsen SF, Saffery R, Vaag A.

Diabetologia. 2018 Apr;61(4):870-880. doi: 10.1007/s00125-018-4549-7. Epub 2018 Jan 23.


Prevalence of micro- and macrovascular diabetes complications at time of type 2 diabetes diagnosis and associated clinical characteristics: A cross-sectional baseline study of 6958 patients in the Danish DD2 cohort.

Gedebjerg A, Almdal TP, Berencsi K, Rungby J, Nielsen JS, Witte DR, Friborg S, Brandslund I, Vaag A, Beck-Nielsen H, Sørensen HT, Thomsen RW.

J Diabetes Complications. 2018 Jan;32(1):34-40. doi: 10.1016/j.jdiacomp.2017.09.010. Epub 2017 Sep 19.


Dnmt3a is an epigenetic mediator of adipose insulin resistance.

You D, Nilsson E, Tenen DE, Lyubetskaya A, Lo JC, Jiang R, Deng J, Dawes BA, Vaag A, Ling C, Rosen ED, Kang S.

Elife. 2017 Nov 1;6. pii: e30766. doi: 10.7554/eLife.30766.


DNA methylation and gene expression of TXNIP in adult offspring of women with diabetes in pregnancy.

Houshmand-Oeregaard A, Hjort L, Kelstrup L, Hansen NS, Broholm C, Gillberg L, Clausen TD, Mathiesen ER, Damm P, Vaag A.

PLoS One. 2017 Oct 27;12(10):e0187038. doi: 10.1371/journal.pone.0187038. eCollection 2017.


Escitalopram Ameliorates Hypercortisolemia and Insulin Resistance in Low Birth Weight Men With Limbic Brain Alterations.

Buhl CS, Stødkilde-Jørgensen H, Videbech P, Vaag A, Møller N, Lund S, Buhl ES.

J Clin Endocrinol Metab. 2018 Jan 1;103(1):115-124. doi: 10.1210/jc.2017-01438.


Adiposity, Dysmetabolic Traits, and Earlier Onset of Female Puberty in Adolescent Offspring of Women With Gestational Diabetes Mellitus: A Clinical Study Within the Danish National Birth Cohort.

Grunnet LG, Hansen S, Hjort L, Madsen CM, Kampmann FB, Thuesen ACB, Granstrømi C, Strøm M, Maslova E, Frikke-Schmidt R, Damm P, Chavarro JE, Hu FB, Olsen SF, Vaag A.

Diabetes Care. 2017 Dec;40(12):1746-1755. doi: 10.2337/dc17-0514. Epub 2017 Oct 16.


Effect of an Intensive Lifestyle Intervention on Glycemic Control in Patients With Type 2 Diabetes: A Randomized Clinical Trial.

Johansen MY, MacDonald CS, Hansen KB, Karstoft K, Christensen R, Pedersen M, Hansen LS, Zacho M, Wedell-Neergaard AS, Nielsen ST, Iepsen UW, Langberg H, Vaag AA, Pedersen BK, Ried-Larsen M.

JAMA. 2017 Aug 15;318(7):637-646. doi: 10.1001/jama.2017.10169.


Insulin secretion and action in North Indian women during pregnancy.

Arora GP, Almgren P, Thaman RG, Pal A, Groop L, Vaag A, Prasad RB, Brøns C.

Diabet Med. 2017 Oct;34(10):1477-1482. doi: 10.1111/dme.13428. Epub 2017 Aug 17.


Dysregulation of a novel miR-23b/27b-p53 axis impairs muscle stem cell differentiation of humans with type 2 diabetes.

Henriksen TI, Davidsen PK, Pedersen M, Schultz HS, Hansen NS, Larsen TJ, Vaag A, Pedersen BK, Nielsen S, Scheele C.

Mol Metab. 2017 Apr 27;6(7):770-779. doi: 10.1016/j.molmet.2017.04.006. eCollection 2017 Jul.


Maternal protein intake in pregnancy and offspring metabolic health at age 9-16 y: results from a Danish cohort of gestational diabetes mellitus pregnancies and controls.

Maslova E, Hansen S, Grunnet LG, Strøm M, Bjerregaard AA, Hjort L, Kampmann FB, Madsen CM, Baun Thuesen AC, Bech BH, Halldorsson TI, Vaag AA, Olsen SF.

Am J Clin Nutr. 2017 Aug;106(2):623-636. doi: 10.3945/ajcn.115.128637. Epub 2017 Jul 5.


Ponderal index at birth associates with later risk of gestational diabetes mellitus.

Crusell M, Damm P, Hansen T, Pedersen O, Glümer C, Vaag A, Lauenborg J.

Arch Gynecol Obstet. 2017 Aug;296(2):249-256. doi: 10.1007/s00404-017-4427-4. Epub 2017 Jun 17.


Complement factors C4 and C3 are down regulated in response to short term overfeeding in healthy young men.

Foghmar C, Brøns C, Pilely K, Vaag A, Garred P.

Sci Rep. 2017 Apr 27;7(1):1235. doi: 10.1038/s41598-017-01382-3.


36 h fasting of young men influences adipose tissue DNA methylation of LEP and ADIPOQ in a birth weight-dependent manner.

Hjort L, Jørgensen SW, Gillberg L, Hall E, Brøns C, Frystyk J, Vaag AA, Ling C.

Clin Epigenetics. 2017 Apr 21;9:40. doi: 10.1186/s13148-017-0340-8. eCollection 2017.


Differential adipokine DNA methylation and gene expression in subcutaneous adipose tissue from adult offspring of women with diabetes in pregnancy.

Houshmand-Oeregaard A, Hansen NS, Hjort L, Kelstrup L, Broholm C, Mathiesen ER, Clausen TD, Damm P, Vaag A.

Clin Epigenetics. 2017 Apr 13;9:37. doi: 10.1186/s13148-017-0338-2. eCollection 2017.


Long-term effect of smartphone-delivered Interval Walking Training on physical activity in patients with type 2 diabetes: protocol for a parallel group single-blinded randomised controlled trial.

Valentiner LS, Ried-Larsen M, Karstoft K, Brinkløv CF, Brøns C, Nielsen RO, Christensen R, Nielsen JS, Vaag AA, Pedersen BK, Langberg H.

BMJ Open. 2017 Apr 7;7(4):e014036. doi: 10.1136/bmjopen-2016-014036.


Childhood body mass index and development of type 2 diabetes throughout adult life-A large-scale danish cohort study.

Zimmermann E, Bjerregaard LG, Gamborg M, Vaag AA, Sørensen TIA, Baker JL.

Obesity (Silver Spring). 2017 May;25(5):965-971. doi: 10.1002/oby.21820. Epub 2017 Mar 27.


A retrospective analysis of a societal experiment among the Danish population suggests that exposure to extra doses of vitamin A during fetal development may lower type 2 diabetes mellitus (T2DM) risk later in life.

Keller A, Ängquist L, Jacobsen R, Vaag A, Heitmann BL.

Br J Nutr. 2017 Mar;117(5):731-736. doi: 10.1017/S000711451700037X. Epub 2017 Mar 27.


Abnormal epigenetic changes during differentiation of human skeletal muscle stem cells from obese subjects.

Davegårdh C, Broholm C, Perfilyev A, Henriksen T, García-Calzón S, Peijs L, Hansen NS, Volkov P, Kjøbsted R, Wojtaszewski JF, Pedersen M, Pedersen BK, Ballak DB, Dinarello CA, Heinhuis B, Joosten LA, Nilsson E, Vaag A, Scheele C, Ling C.

BMC Med. 2017 Feb 22;15(1):39. doi: 10.1186/s12916-017-0792-x.


Fetal Hyperglycemia Changes Human Preadipocyte Function in Adult Life.

Hansen NS, Strasko KS, Hjort L, Kelstrup L, Houshmand-Øregaard A, Schrölkamp M, Schultz HS, Scheele C, Pedersen BK, Ling C, Clausen TD, Damm P, Vaag A, Broholm C.

J Clin Endocrinol Metab. 2017 Apr 1;102(4):1141-1150. doi: 10.1210/jc.2016-3907.


Criterion validity and reliability of a smartphone delivered sub-maximal fitness test for people with type 2 diabetes.

Brinkløv CF, Thorsen IK, Karstoft K, Brøns C, Valentiner L, Langberg H, Vaag AA, Nielsen JS, Pedersen BK, Ried-Larsen M.

BMC Sports Sci Med Rehabil. 2016 Oct 7;8:31. doi: 10.1186/s13102-016-0056-7. eCollection 2016.


Diagnosing gestational diabetes mellitus in the Danish National Birth Cohort.

Olsen SF, Houshmand-Oeregaard A, Granström C, Langhoff-Roos J, Damm P, Bech BH, Vaag AA, Zhang C.

Acta Obstet Gynecol Scand. 2017 May;96(5):563-569. doi: 10.1111/aogs.13083. Epub 2017 Feb 9.


Plasma amino acid levels are elevated in young, healthy low birth weight men exposed to short-term high-fat overfeeding.

Ribel-Madsen A, Hellgren LI, Brøns C, Ribel-Madsen R, Newgard CB, Vaag AA.

Physiol Rep. 2016 Dec;4(23). pii: e13044.


Human adipogenesis is associated with genome-wide DNA methylation and gene-expression changes.

Broholm C, Olsson AH, Perfilyev A, Gillberg L, Hansen NS, Ali A, Mortensen B, Ling C, Vaag A.

Epigenomics. 2016 Dec;8(12):1601-1617. Epub 2016 Nov 17.


Impact of the TCF7L2 genotype on risk of hypoglycaemia and glucagon secretion during hypoglycaemia.

Kristensen PL, Pedersen-Bjergaard U, Due-Andersen R, Høi-Hansen T, Grimmeshave L, Lyssenko V, Groop L, Holst JJ, Vaag AA, Thorsteinsson B.

Endocr Connect. 2016 Nov;5(6):53-60. Epub 2016 Oct 10.


Plasma acylcarnitine profiling indicates increased fatty acid oxidation relative to tricarboxylic acid cycle capacity in young, healthy low birth weight men.

Ribel-Madsen A, Ribel-Madsen R, Brøns C, Newgard CB, Vaag AA, Hellgren LI.

Physiol Rep. 2016 Oct;4(19). pii: e12977.


Genome-wide associations for birth weight and correlations with adult disease.

Horikoshi M, Beaumont RN, Day FR, Warrington NM, Kooijman MN, Fernandez-Tajes J, Feenstra B, van Zuydam NR, Gaulton KJ, Grarup N, Bradfield JP, Strachan DP, Li-Gao R, Ahluwalia TS, Kreiner E, Rueedi R, Lyytikäinen LP, Cousminer DL, Wu Y, Thiering E, Wang CA, Have CT, Hottenga JJ, Vilor-Tejedor N, Joshi PK, Boh ETH, Ntalla I, Pitkänen N, Mahajan A, van Leeuwen EM, Joro R, Lagou V, Nodzenski M, Diver LA, Zondervan KT, Bustamante M, Marques-Vidal P, Mercader JM, Bennett AJ, Rahmioglu N, Nyholt DR, Ma RCW, Tam CHT, Tam WH; CHARGE Consortium Hematology Working Group, Ganesh SK, van Rooij FJ, Jones SE, Loh PR, Ruth KS, Tuke MA, Tyrrell J, Wood AR, Yaghootkar H, Scholtens DM, Paternoster L, Prokopenko I, Kovacs P, Atalay M, Willems SM, Panoutsopoulou K, Wang X, Carstensen L, Geller F, Schraut KE, Murcia M, van Beijsterveldt CE, Willemsen G, Appel EVR, Fonvig CE, Trier C, Tiesler CM, Standl M, Kutalik Z, Bonas-Guarch S, Hougaard DM, Sánchez F, Torrents D, Waage J, Hollegaard MV, de Haan HG, Rosendaal FR, Medina-Gomez C, Ring SM, Hemani G, McMahon G, Robertson NR, Groves CJ, Langenberg C, Luan J, Scott RA, Zhao JH, Mentch FD, MacKenzie SM, Reynolds RM; Early Growth Genetics (EGG) Consortium, Lowe WL Jr, Tönjes A, Stumvoll M, Lindi V, Lakka TA, van Duijn CM, Kiess W, Körner A, Sørensen TI, Niinikoski H, Pahkala K, Raitakari OT, Zeggini E, Dedoussis GV, Teo YY, Saw SM, Melbye M, Campbell H, Wilson JF, Vrijheid M, de Geus EJ, Boomsma DI, Kadarmideen HN, Holm JC, Hansen T, Sebert S, Hattersley AT, Beilin LJ, Newnham JP, Pennell CE, Heinrich J, Adair LS, Borja JB, Mohlke KL, Eriksson JG, Widén EE, Kähönen M, Viikari JS, Lehtimäki T, Vollenweider P, Bønnelykke K, Bisgaard H, Mook-Kanamori DO, Hofman A, Rivadeneira F, Uitterlinden AG, Pisinger C, Pedersen O, Power C, Hyppönen E, Wareham NJ, Hakonarson H, Davies E, Walker BR, Jaddoe VW, Jarvelin MR, Grant SF, Vaag AA, Lawlor DA, Frayling TM, Davey Smith G, Morris AP, Ong KK, Felix JF, Timpson NJ, Perry JR, Evans DM, McCarthy MI, Freathy RM.

Nature. 2016 Oct 13;538(7624):248-252. doi: 10.1038/nature19806. Epub 2016 Sep 28.


Epigenetic programming of adipose-derived stem cells in low birthweight individuals.

Broholm C, Olsson AH, Perfilyev A, Hansen NS, Schrölkamp M, Strasko KS, Scheele C, Ribel-Madsen R, Mortensen B, Jørgensen SW, Ling C, Vaag A.

Diabetologia. 2016 Dec;59(12):2664-2673. Epub 2016 Sep 14.


Microchimerism of male origin in a cohort of Danish girls.

Müller AC, Jakobsen MA, Barington T, Vaag AA, Grunnet LG, Olsen SF, Kamper-Jørgensen M.

Chimerism. 2015 Oct 2;6(4):65-71. doi: 10.1080/19381956.2016.1218583. Epub 2016 Aug 11.


DNA methylation and gene expression of HIF3A: cross-tissue validation and associations with BMI and insulin resistance.

Main AM, Gillberg L, Jacobsen AL, Nilsson E, Gjesing AP, Hansen T, Pedersen O, Ribel-Madsen R, Vaag A.

Clin Epigenetics. 2016 Sep 2;8:89. doi: 10.1186/s13148-016-0258-6. eCollection 2016.


Gene Expression and DNA Methylation of PPARGC1A in Muscle and Adipose Tissue From Adult Offspring of Women With Diabetes in Pregnancy.

Kelstrup L, Hjort L, Houshmand-Oeregaard A, Clausen TD, Hansen NS, Broholm C, Borch-Johnsen L, Mathiesen ER, Vaag AA, Damm P.

Diabetes. 2016 Oct;65(10):2900-10. doi: 10.2337/db16-0227. Epub 2016 Jul 7.


Implementation of interval walking training in patients with type 2 diabetes in Denmark: rationale, design, and baseline characteristics.

Ried-Larsen M, Thomsen RW, Berencsi K, Brinkløv CF, Brøns C, Valentiner LS, Karstoft K, Langberg H, Vaag AA, Pedersen BK, Nielsen JS.

Clin Epidemiol. 2016 Jun 8;8:201-9. doi: 10.2147/CLEP.S97303. eCollection 2016.


Rates of Community-based Antibiotic Prescriptions and Hospital-treated Infections in Individuals With and Without Type 2 Diabetes: A Danish Nationwide Cohort Study, 2004-2012.

Mor A, Berencsi K, Nielsen JS, Rungby J, Friborg S, Brandslund I, Christiansen JS, Vaag A, Beck-Nielsen H, Sørensen HT, Thomsen RW.

Clin Infect Dis. 2016 Aug 15;63(4):501-11. doi: 10.1093/cid/ciw345. Epub 2016 Jun 26.


A Genome-Wide mQTL Analysis in Human Adipose Tissue Identifies Genetic Variants Associated with DNA Methylation, Gene Expression and Metabolic Traits.

Volkov P, Olsson AH, Gillberg L, Jørgensen SW, Brøns C, Eriksson KF, Groop L, Jansson PA, Nilsson E, Rönn T, Vaag A, Ling C.

PLoS One. 2016 Jun 20;11(6):e0157776. doi: 10.1371/journal.pone.0157776. eCollection 2016.


Endocrine and metabolic diurnal rhythms in young adult men born small vs appropriate for gestational age.

Brøns C, Saltbæk PN, Friedrichsen M, Chen Y, Vaag A.

Eur J Endocrinol. 2016 Jul;175(1):29-40. doi: 10.1530/EJE-16-0177.


DNA methylation of loci within ABCG1 and PHOSPHO1 in blood DNA is associated with future type 2 diabetes risk.

Dayeh T, Tuomi T, Almgren P, Perfilyev A, Jansson PA, de Mello VD, Pihlajamäki J, Vaag A, Groop L, Nilsson E, Ling C.

Epigenetics. 2016 Jul 2;11(7):482-8. doi: 10.1080/15592294.2016.1178418. Epub 2016 May 5.


Vitamin D fortification and seasonality of birth in type 1 diabetic cases: D-tect study - ERRATUM.

Jacobsen R, Moldovan M, Vaag AA, Hypponen E, Heitmann BL.

J Dev Orig Health Dis. 2016 Aug;7(4):429. doi: 10.1017/S2040174416000155. Epub 2016 Apr 18. No abstract available.


A common variation of the PTEN gene is associated with peripheral insulin resistance.

Grinder-Hansen L, Ribel-Madsen R, Wojtaszewski JF, Poulsen P, Grunnet LG, Vaag A.

Diabetes Metab. 2016 Sep;42(4):280-4. doi: 10.1016/j.diabet.2016.03.003. Epub 2016 Apr 8.


Blood-based biomarkers of age-associated epigenetic changes in human islets associate with insulin secretion and diabetes.

Bacos K, Gillberg L, Volkov P, Olsson AH, Hansen T, Pedersen O, Gjesing AP, Eiberg H, Tuomi T, Almgren P, Groop L, Eliasson L, Vaag A, Dayeh T, Ling C.

Nat Commun. 2016 Mar 31;7:11089. doi: 10.1038/ncomms11089.


Metabolic and Transcriptional Changes in Cultured Muscle Stem Cells from Low Birth Weight Subjects.

Hansen NS, Hjort L, Broholm C, Gillberg L, Schrölkamp M, Schultz HS, Mortensen B, Jørgensen SW, Friedrichsen M, Wojtaszewski JF, Pedersen BK, Vaag A.

J Clin Endocrinol Metab. 2016 May;101(5):2254-64. doi: 10.1210/jc.2015-4214. Epub 2016 Mar 22.


EMPA-REG: Glucose excretion and lipid mobilization - not storage - saves lives.

Jørgensen NB, Pedersen J, Vaag AA.

J Diabetes Complications. 2016 May-Jun;30(4):753. doi: 10.1016/j.jdiacomp.2016.02.015. Epub 2016 Feb 23. No abstract available.


Supplemental Content

Support Center