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Items: 1 to 50 of 131

1.

cIAP1/2 inhibition synergizes with TNF inhibition in autoimmunity by down-regulating IL-17A and inducing Tregs.

Kawalkowska JZ, Ogbechi J, Venables PJ, Williams RO.

Sci Adv. 2019 May 1;5(5):eaaw5422. doi: 10.1126/sciadv.aaw5422. eCollection 2019 May.

2.

Colorectal cancer liver metastatic growth depends on PAD4-driven citrullination of the extracellular matrix.

Yuzhalin AE, Gordon-Weeks AN, Tognoli ML, Jones K, Markelc B, Konietzny R, Fischer R, Muth A, O'Neill E, Thompson PR, Venables PJ, Kessler BM, Lim SY, Muschel RJ.

Nat Commun. 2018 Nov 14;9(1):4783. doi: 10.1038/s41467-018-07306-7.

3.

Time to Include Fine Specificity Anti-Citrullinated Protein Antibodies in the Routine Diagnosis and Management of Rheumatoid Arthritis?

Schwenzer A, Quirke AM, Montgomery AB, Venables PJ, Sayles HR, Schlumberger W, Payne JB, Mikuls TR, Midwood KS.

Arthritis Rheumatol. 2019 Mar;71(3):476-478. doi: 10.1002/art.40767. Epub 2019 Feb 9. No abstract available.

4.

High erythrocyte levels of the n-6 polyunsaturated fatty acid linoleic acid are associated with lower risk of subsequent rheumatoid arthritis in a southern European nested case-control study.

de Pablo P, Romaguera D, Fisk HL, Calder PC, Quirke AM, Cartwright AJ, Panico S, Mattiello A, Gavrila D, Navarro C, Sacerdote C, Vineis P, Tumino R, Ollier WE, Michaud DS, Riboli E, Venables PJ, Fisher BA.

Ann Rheum Dis. 2018 Jul;77(7):981-987. doi: 10.1136/annrheumdis-2017-212274. Epub 2018 Feb 7.

5.

Association of Distinct Fine Specificities of Anti-Citrullinated Peptide Antibodies With Elevated Immune Responses to Prevotella intermedia in a Subgroup of Patients With Rheumatoid Arthritis and Periodontitis.

Schwenzer A, Quirke AM, Marzeda AM, Wong A, Montgomery AB, Sayles HR, Eick S, Gawron K, Chomyszyn-Gajewska M, Łazarz-Bartyzel K, Davis S, Potempa J, Kessler BM, Fischer R, Venables PJ, Payne JB, Mikuls TR, Midwood KS.

Arthritis Rheumatol. 2017 Dec;69(12):2303-2313. doi: 10.1002/art.40227. Epub 2017 Oct 30.

6.

Abrogation of collagen-induced arthritis by a peptidyl arginine deiminase inhibitor is associated with modulation of T cell-mediated immune responses.

Kawalkowska J, Quirke AM, Ghari F, Davis S, Subramanian V, Thompson PR, Williams RO, Fischer R, La Thangue NB, Venables PJ.

Sci Rep. 2016 May 23;6:26430. doi: 10.1038/srep26430.

7.

Citrullination-acetylation interplay guides E2F-1 activity during the inflammatory response.

Ghari F, Quirke AM, Munro S, Kawalkowska J, Picaud S, McGouran J, Subramanian V, Muth A, Williams R, Kessler B, Thompson PR, Fillipakopoulos P, Knapp S, Venables PJ, La Thangue NB.

Sci Adv. 2016 Feb 5;2(2):e1501257. doi: 10.1126/sciadv.1501257. eCollection 2016 Feb.

8.

Erratum to: Smoking, Porphyromonas gingivalis and the immune response to citrullinated autoantigens before the clinical onset of rheumatoid arthritis in a Southern European nested case-control study.

Fisher BA, Cartwright AJ, Quirke AM, de Pablo P, Romaguera D, Panico S, Mattiello A, Gavrila D, Navarro C, Sacerdote C, Vineis P, Tumino R, Lappin DF, Apatzidou D, Culshaw S, Potempa J, Michaud DS, Riboli E, Venables PJ.

BMC Musculoskelet Disord. 2016 Feb 5;17:62. doi: 10.1186/s12891-016-0916-z. No abstract available.

9.

Identification of an immunodominant peptide from citrullinated tenascin-C as a major target for autoantibodies in rheumatoid arthritis.

Schwenzer A, Jiang X, Mikuls TR, Payne JB, Sayles HR, Quirke AM, Kessler BM, Fischer R, Venables PJ, Lundberg K, Midwood KS.

Ann Rheum Dis. 2016 Oct;75(10):1876-83. doi: 10.1136/annrheumdis-2015-208495. Epub 2015 Dec 9.

10.

Antibodies to Porphyromonas gingivalis Indicate Interaction Between Oral Infection, Smoking, and Risk Genes in Rheumatoid Arthritis Etiology.

Kharlamova N, Jiang X, Sherina N, Potempa B, Israelsson L, Quirke AM, Eriksson K, Yucel-Lindberg T, Venables PJ, Potempa J, Alfredsson L, Lundberg K.

Arthritis Rheumatol. 2016 Mar;68(3):604-13. doi: 10.1002/art.39491.

11.

Smoking, Porphyromonas gingivalis and the immune response to citrullinated autoantigens before the clinical onset of rheumatoid arthritis in a Southern European nested case-control study.

Fisher BA, Cartwright AJ, Quirke AM, de Pablo P, Romaguera D, Panico S, Mattiello A, Gavrila D, Navarro C, Sacerdote C, Vineis P, Tumino R, Lappin DF, Apatzidou D, Culshaw S, Potempa J, Michaud DS, Riboli E, Venables PJ.

BMC Musculoskelet Disord. 2015 Nov 4;16:331. doi: 10.1186/s12891-015-0792-y. Erratum in: BMC Musculoskelet Disord. 2016;17:62. Apazidou, Danae [corrected to Apatzidou, Danae].

12.

Citrullination in the periodontium--a possible link between periodontitis and rheumatoid arthritis.

Laugisch O, Wong A, Sroka A, Kantyka T, Koziel J, Neuhaus K, Sculean A, Venables PJ, Potempa J, Möller B, Eick S.

Clin Oral Investig. 2016 May;20(4):675-83. doi: 10.1007/s00784-015-1556-7. Epub 2015 Aug 13.

13.

Crystal structure of Porphyromonas gingivalis peptidylarginine deiminase: implications for autoimmunity in rheumatoid arthritis.

Montgomery AB, Kopec J, Shrestha L, Thezenas ML, Burgess-Brown NA, Fischer R, Yue WW, Venables PJ.

Ann Rheum Dis. 2016 Jun;75(6):1255-61. doi: 10.1136/annrheumdis-2015-207656. Epub 2015 Jul 24.

14.

Bronchiectasis is a Model for Chronic Bacterial Infection Inducing Autoimmunity in Rheumatoid Arthritis.

Quirke AM, Perry E, Cartwright A, Kelly C, De Soyza A, Eggleton P, Hutchinson D, Venables PJ.

Arthritis Rheumatol. 2015 Sep;67(9):2335-42. doi: 10.1002/art.39226.

15.

Expression of citrulline and homocitrulline residues in the lungs of non-smokers and smokers: implications for autoimmunity in rheumatoid arthritis.

Lugli EB, Correia RE, Fischer R, Lundberg K, Bracke KR, Montgomery AB, Kessler BM, Brusselle GG, Venables PJ.

Arthritis Res Ther. 2015 Jan 20;17:9. doi: 10.1186/s13075-015-0520-x.

16.

PPAD remains a credible candidate for inducing autoimmunity in rheumatoid arthritis: comment on the article by Konig et al.

Quirke AM, Lundberg K, Potempa J, Mikuls TR, Venables PJ.

Ann Rheum Dis. 2015 Jan;74(1):e7. doi: 10.1136/annrheumdis-2014-206665. Epub 2014 Oct 13. No abstract available.

PMID:
25311822
17.
18.

The case for measuring antibodies to specific citrullinated antigens.

Montgomery AB, Venables PJ, Fisher BA.

Expert Rev Clin Immunol. 2013 Dec;9(12):1185-92. doi: 10.1586/1744666X.2013.857274. Review.

PMID:
24215408
19.

Porphyromonas gingivalis facilitates the development and progression of destructive arthritis through its unique bacterial peptidylarginine deiminase (PAD).

Maresz KJ, Hellvard A, Sroka A, Adamowicz K, Bielecka E, Koziel J, Gawron K, Mizgalska D, Marcinska KA, Benedyk M, Pyrc K, Quirke AM, Jonsson R, Alzabin S, Venables PJ, Nguyen KA, Mydel P, Potempa J.

PLoS Pathog. 2013 Sep;9(9):e1003627. doi: 10.1371/journal.ppat.1003627. Epub 2013 Sep 12.

20.

Heightened immune response to autocitrullinated Porphyromonas gingivalis peptidylarginine deiminase: a potential mechanism for breaching immunologic tolerance in rheumatoid arthritis.

Quirke AM, Lugli EB, Wegner N, Hamilton BC, Charles P, Chowdhury M, Ytterberg AJ, Zubarev RA, Potempa J, Culshaw S, Guo Y, Fisher BA, Thiele G, Mikuls TR, Venables PJ.

Ann Rheum Dis. 2014 Jan;73(1):263-9. doi: 10.1136/annrheumdis-2012-202726. Epub 2013 Mar 5.

21.

The autoantibody repertoire in periodontitis: a role in the induction of autoimmunity to citrullinated proteins in rheumatoid arthritis?

de Pablo P, Dietrich T, Chapple IL, Milward M, Chowdhury M, Charles PJ, Buckley CD, Venables PJ.

Ann Rheum Dis. 2014 Mar;73(3):580-6. doi: 10.1136/annrheumdis-2012-202701. Epub 2013 Feb 23.

PMID:
23434568
22.

Heterogeneity of anticitrullinated peptide antibodies and response to anti-tumor necrosis factor agents in rheumatoid arthritis.

Fisher BA, Plant D, Lundberg K, Charles P, Barton A, Venables PJ; Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate (BRAGGSS).

J Rheumatol. 2012 May;39(5):929-32. doi: 10.3899/jrheum.111315. Epub 2012 Apr 1.

PMID:
22467927
23.

Inhibiting citrullination in rheumatoid arthritis: taking fuel from the fire.

Fisher BA, Venables PJ.

Arthritis Res Ther. 2012 Feb 29;14(1):108. doi: 10.1186/ar3740. No abstract available.

24.

Etiology of autoimmune disease: past, present and future.

Alzabin S, Venables PJ.

Expert Rev Clin Immunol. 2012 Feb;8(2):111-3. doi: 10.1586/eci.11.88. Review. No abstract available.

PMID:
22288447
25.

Immunization with Porphyromonas gingivalis enolase induces autoimmunity to mammalian α-enolase and arthritis in DR4-IE-transgenic mice.

Kinloch AJ, Alzabin S, Brintnell W, Wilson E, Barra L, Wegner N, Bell DA, Cairns E, Venables PJ.

Arthritis Rheum. 2011 Dec;63(12):3818-23. doi: 10.1002/art.30639.

26.

Citrullination of autoantigens: upstream of TNFα in the pathogenesis of rheumatoid arthritis.

Quirke AM, Fisher BA, Kinloch AJ, Venables PJ.

FEBS Lett. 2011 Dec 1;585(23):3681-8. doi: 10.1016/j.febslet.2011.06.006. Epub 2011 Jun 23. Review.

27.

Serotyping for an extended anti-citrullinated peptide autoantibody panel does not add value to CCP2 testing for diagnosing RA in an early undifferentiated arthritis cohort.

Pratt AG, Charles PJ, Chowdhury M, Wilson G, Venables PJ, Isaacs JD.

Ann Rheum Dis. 2011 Nov;70(11):2056-8. doi: 10.1136/ard.2010.148197. Epub 2011 May 27. No abstract available.

PMID:
21622767
28.

Antibodies to citrullinated α-enolase peptide 1 and clinical and radiological outcomes in rheumatoid arthritis.

Fisher BA, Plant D, Brode M, van Vollenhoven RF, Mathsson L, Symmons D, Lundberg K, Rönnelid J, Venables PJ.

Ann Rheum Dis. 2011 Jun;70(6):1095-8. doi: 10.1136/ard.2010.138909. Epub 2011 Mar 1.

PMID:
21367760
29.

Periodontitis in RA-the citrullinated enolase connection.

Lundberg K, Wegner N, Yucel-Lindberg T, Venables PJ.

Nat Rev Rheumatol. 2010 Dec;6(12):727-30. doi: 10.1038/nrrheum.2010.139. Epub 2010 Sep 7. Review.

PMID:
20820197
30.

Bacterial and human peptidylarginine deiminases: targets for inhibiting the autoimmune response in rheumatoid arthritis?

Mangat P, Wegner N, Venables PJ, Potempa J.

Arthritis Res Ther. 2010;12(3):209. doi: 10.1186/ar3000. Epub 2010 Jun 2. Review.

31.

Peptidylarginine deiminase from Porphyromonas gingivalis citrullinates human fibrinogen and α-enolase: implications for autoimmunity in rheumatoid arthritis.

Wegner N, Wait R, Sroka A, Eick S, Nguyen KA, Lundberg K, Kinloch A, Culshaw S, Potempa J, Venables PJ.

Arthritis Rheum. 2010 Sep;62(9):2662-72. doi: 10.1002/art.27552.

32.

Organ-specific autoantibodies but not anti-cyclic citrullinated peptides are a feature of autoimmunity in Down's syndrome.

Fisher BA, Charles P, Lundberg K, Gillespie KM, Newton RW, Venables PJ.

Ann Rheum Dis. 2010 May;69(5):939-40. doi: 10.1136/ard.2009.112458. Epub 2010 Apr 13. No abstract available.

PMID:
20388737
33.

Autoimmunity to specific citrullinated proteins gives the first clues to the etiology of rheumatoid arthritis.

Wegner N, Lundberg K, Kinloch A, Fisher B, Malmström V, Feldmann M, Venables PJ.

Immunol Rev. 2010 Jan;233(1):34-54. doi: 10.1111/j.0105-2896.2009.00850.x. Review.

PMID:
20192991
34.

Antibodies to several citrullinated antigens are enriched in the joints of rheumatoid arthritis patients.

Snir O, Widhe M, Hermansson M, von Spee C, Lindberg J, Hensen S, Lundberg K, Engström A, Venables PJ, Toes RE, Holmdahl R, Klareskog L, Malmström V.

Arthritis Rheum. 2010 Jan;62(1):44-52. doi: 10.1002/art.25036.

35.

Specific interaction between genotype, smoking and autoimmunity to citrullinated alpha-enolase in the etiology of rheumatoid arthritis.

Mahdi H, Fisher BA, Källberg H, Plant D, Malmström V, Rönnelid J, Charles P, Ding B, Alfredsson L, Padyukov L, Symmons DP, Venables PJ, Klareskog L, Lundberg K.

Nat Genet. 2009 Dec;41(12):1319-24. doi: 10.1038/ng.480. Epub 2009 Nov 8.

PMID:
19898480
36.

Sinonasal sarcoid.

Bakshi J, Venables PJ, Abraham S.

J Postgrad Med. 2009 Jan-Mar;55(1):43-4. No abstract available.

37.

Epitope spreading in animal models: array of hope in rheumatoid arthritis and multiple sclerosis.

Lundberg K, Venables PJ.

Arthritis Res Ther. 2008;10(6):122. doi: 10.1186/ar2544. Epub 2008 Nov 25.

38.

Evolutionarily conserved antigens in autoimmune disease: implications for an infective aetiology.

Wegner N, Wait R, Venables PJ.

Int J Biochem Cell Biol. 2009 Feb;41(2):390-7. doi: 10.1016/j.biocel.2008.09.012. Epub 2008 Sep 24. Review.

PMID:
18926919
39.

Antibodies to citrullinated alpha-enolase peptide 1 are specific for rheumatoid arthritis and cross-react with bacterial enolase.

Lundberg K, Kinloch A, Fisher BA, Wegner N, Wait R, Charles P, Mikuls TR, Venables PJ.

Arthritis Rheum. 2008 Oct;58(10):3009-19. doi: 10.1002/art.23936.

40.

Synovial fluid is a site of citrullination of autoantigens in inflammatory arthritis.

Kinloch A, Lundberg K, Wait R, Wegner N, Lim NH, Zendman AJ, Saxne T, Malmström V, Venables PJ.

Arthritis Rheum. 2008 Aug;58(8):2287-95. doi: 10.1002/art.23618.

41.

Multiple antibody reactivities to citrullinated antigens in sera from patients with rheumatoid arthritis: association with HLA-DRB1 alleles.

Snir O, Widhe M, von Spee C, Lindberg J, Padyukov L, Lundberg K, Engström A, Venables PJ, Lundeberg J, Holmdahl R, Klareskog L, Malmström V.

Ann Rheum Dis. 2009 May;68(5):736-43. doi: 10.1136/ard.2008.091355. Epub 2008 Jul 17.

PMID:
18635594
42.

Is Sjogren myelopathy Devic disease?

Sofat N, Venables PJ.

Ann Rheum Dis. 2008 May;67(5):730-1. doi: 10.1136/ard.2007.077883. No abstract available.

PMID:
18408117
43.

HERV-K113 is not associated with multiple sclerosis in a large family-based study.

Moyes DL, Goris A, Ban M, Compston A, Griffiths DJ, Sawcer S, Venables PJ.

AIDS Res Hum Retroviruses. 2008 Mar;24(3):363-5. doi: 10.1089/aid.2007.0196.

PMID:
18327982
44.

Insertional polymorphisms: a new lease of life for endogenous retroviruses in human disease.

Moyes D, Griffiths DJ, Venables PJ.

Trends Genet. 2007 Jul;23(7):326-33. Epub 2007 May 23. Review.

PMID:
17524519
45.

Management of patients presenting with Sjogren's syndrome.

Venables PJ.

Best Pract Res Clin Rheumatol. 2006 Aug;20(4):791-807. Review.

PMID:
16979538
46.

Pathogenic role of antibodies to citrullinated proteins in rheumatoid arthritis.

Kinloch AJ, Lundberg KE, Moyes D, Venables PJ.

Expert Rev Clin Immunol. 2006 May;2(3):365-75. doi: 10.1586/1744666X.2.3.365.

PMID:
20476908
47.

Mixed connective tissue disease.

Venables PJ.

Lupus. 2006;15(3):132-7. Review.

PMID:
16634365
48.

Identification of citrullinated alpha-enolase as a candidate autoantigen in rheumatoid arthritis.

Kinloch A, Tatzer V, Wait R, Peston D, Lundberg K, Donatien P, Moyes D, Taylor PC, Venables PJ.

Arthritis Res Ther. 2005;7(6):R1421-9. Epub 2005 Oct 19.

49.

The distribution of the endogenous retroviruses HERV-K113 and HERV-K115 in health and disease.

Moyes DL, Martin A, Sawcer S, Temperton N, Worthington J, Griffiths DJ, Venables PJ.

Genomics. 2005 Sep;86(3):337-41.

PMID:
16024218
50.

Sjögren's syndrome.

Venables PJ.

Best Pract Res Clin Rheumatol. 2004 Jun;18(3):313-29. Review.

PMID:
15158743

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