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Items: 1 to 50 of 106

1.

Evidence on mechanisms and tools for use of health information for decision-making [Internet].

Blessing V, Davé A, Varnai P.

Copenhagen: WHO Regional Office for Europe; 2017.

2.

Heterologous phosphorylation-induced formation of a stability lock permits regulation of inactive receptors by β-arrestins.

Tóth AD, Prokop S, Gyombolai P, Várnai P, Balla A, Gurevich VV, Hunyady L, Turu G.

J Biol Chem. 2018 Jan 19;293(3):876-892. doi: 10.1074/jbc.M117.813139. Epub 2017 Nov 16.

PMID:
29146594
3.

Plasma membrane phosphatidylinositol 4-phosphate and 4,5-bisphosphate determine the distribution and function of K-Ras4B but not H-Ras proteins.

Gulyás G, Radvánszki G, Matuska R, Balla A, Hunyady L, Balla T, Várnai P.

J Biol Chem. 2017 Nov 17;292(46):18862-18877. doi: 10.1074/jbc.M117.806679. Epub 2017 Sep 22.

PMID:
28939768
4.

MSTO1 is a cytoplasmic pro-mitochondrial fusion protein, whose mutation induces myopathy and ataxia in humans.

Gal A, Balicza P, Weaver D, Naghdi S, Joseph SK, Várnai P, Gyuris T, Horváth A, Nagy L, Seifert EL, Molnar MJ, Hajnóczky G.

EMBO Mol Med. 2017 Jul;9(7):967-984. doi: 10.15252/emmm.201607058.

5.

Quantifying lipid changes in various membrane compartments using lipid binding protein domains.

Várnai P, Gulyás G, Tóth DJ, Sohn M, Sengupta N, Balla T.

Cell Calcium. 2017 Jun;64:72-82. doi: 10.1016/j.ceca.2016.12.008. Epub 2016 Dec 31. Review.

6.

Angiotensin type 1A receptor regulates β-arrestin binding of the β2-adrenergic receptor via heterodimerization.

Tóth AD, Gyombolai P, Szalai B, Várnai P, Turu G, Hunyady L.

Mol Cell Endocrinol. 2017 Feb 15;442:113-124. doi: 10.1016/j.mce.2016.11.027. Epub 2016 Nov 28.

PMID:
27908837
7.

Erratum to: Making sense of big data in health research: towards an EU action plan.

Auffray C, Balling R, Barroso I, Bencze L, Benson M, Bergeron J, Bernal-Delgado E, Blomberg N, Bock C, Conesa A, Del Signore S, Delogne C, Devilee P, Di Meglio A, Eijkemans M, Flicek P, Graf N, Grimm V, Guchelaar HJ, Guo YK, Gut IG, Hanbury A, Hanif S, Hilgers RD, Honrado Á, Hose DR, Houwing-Duistermaat J, Hubbard T, Janacek SH, Karanikas H, Kievits T, Kohler M, Kremer A, Lanfear J, Lengauer T, Maes E, Meert T, Müller W, Nickel D, Oledzki P, Pedersen B, Petkovic M, Pliakos K, Rattray M, I Màs JR, Schneider R, Sengstag T, Serra-Picamal X, Spek W, Vaas LA, van Batenburg O, Vandelaer M, Varnai P, Villoslada P, Vizcaíno JA, Wubbe JP, Zanetti G.

Genome Med. 2016 Nov 7;8(1):118. No abstract available.

8.

Redox Nanodomains Are Induced by and Control Calcium Signaling at the ER-Mitochondrial Interface.

Booth DM, Enyedi B, Geiszt M, Várnai P, Hajnóczky G.

Mol Cell. 2016 Jul 21;63(2):240-248. doi: 10.1016/j.molcel.2016.05.040. Epub 2016 Jul 7.

9.

Making sense of big data in health research: Towards an EU action plan.

Auffray C, Balling R, Barroso I, Bencze L, Benson M, Bergeron J, Bernal-Delgado E, Blomberg N, Bock C, Conesa A, Del Signore S, Delogne C, Devilee P, Di Meglio A, Eijkemans M, Flicek P, Graf N, Grimm V, Guchelaar HJ, Guo YK, Gut IG, Hanbury A, Hanif S, Hilgers RD, Honrado Á, Hose DR, Houwing-Duistermaat J, Hubbard T, Janacek SH, Karanikas H, Kievits T, Kohler M, Kremer A, Lanfear J, Lengauer T, Maes E, Meert T, Müller W, Nickel D, Oledzki P, Pedersen B, Petkovic M, Pliakos K, Rattray M, I Màs JR, Schneider R, Sengstag T, Serra-Picamal X, Spek W, Vaas LA, van Batenburg O, Vandelaer M, Varnai P, Villoslada P, Vizcaíno JA, Wubbe JP, Zanetti G.

Genome Med. 2016 Jun 23;8(1):71. doi: 10.1186/s13073-016-0323-y. Erratum in: Genome Med. 2016 Nov 7;8(1):118.

10.

Correction: Improved Methodical Approach for Quantitative BRET Analysis of G Protein Coupled Receptor Dimerization.

Szalai B, Hoffmann P, Prokop S, Erdélyi L, Várnai P, Hunyady L.

PLoS One. 2016 May 31;11(5):e0156824. doi: 10.1371/journal.pone.0156824. eCollection 2016.

11.

Lenz-Majewski mutations in PTDSS1 affect phosphatidylinositol 4-phosphate metabolism at ER-PM and ER-Golgi junctions.

Sohn M, Ivanova P, Brown HA, Toth DJ, Varnai P, Kim YJ, Balla T.

Proc Natl Acad Sci U S A. 2016 Apr 19;113(16):4314-9. doi: 10.1073/pnas.1525719113. Epub 2016 Apr 4.

12.

BRET-monitoring of the dynamic changes of inositol lipid pools in living cells reveals a PKC-dependent PtdIns4P increase upon EGF and M3 receptor activation.

Tóth JT, Gulyás G, Tóth DJ, Balla A, Hammond GR, Hunyady L, Balla T, Várnai P.

Biochim Biophys Acta. 2016 Mar;1861(3):177-87. doi: 10.1016/j.bbalip.2015.12.005. Epub 2015 Dec 12.

13.

Motifs of VDAC2 required for mitochondrial Bak import and tBid-induced apoptosis.

Naghdi S, Várnai P, Hajnóczky G.

Proc Natl Acad Sci U S A. 2015 Oct 13;112(41):E5590-9. doi: 10.1073/pnas.1510574112. Epub 2015 Sep 28.

14.

Mutation in the V2 vasopressin receptor gene, AVPR2, causes nephrogenic syndrome of inappropriate diuresis.

Erdélyi LS, Mann WA, Morris-Rosendahl DJ, Groß U, Nagel M, Várnai P, Balla A, Hunyady L.

Kidney Int. 2015 Nov;88(5):1070-8. doi: 10.1038/ki.2015.181. Epub 2015 Jul 1.

PMID:
26131744
15.

Measurement of inositol 1,4,5-trisphosphate in living cells using an improved set of resonance energy transfer-based biosensors.

Gulyás G, Tóth JT, Tóth DJ, Kurucz I, Hunyady L, Balla T, Várnai P.

PLoS One. 2015 May 1;10(5):e0125601. doi: 10.1371/journal.pone.0125601. eCollection 2015.

16.

Investigation of the fate of type I angiotensin receptor after biased activation.

Szakadáti G, Tóth AD, Oláh I, Erdélyi LS, Balla T, Várnai P, Hunyady L, Balla A.

Mol Pharmacol. 2015 Jun;87(6):972-81. doi: 10.1124/mol.114.097030. Epub 2015 Mar 24.

17.

Trans-mitochondrial coordination of cristae at regulated membrane junctions.

Picard M, McManus MJ, Csordás G, Várnai P, Dorn GW 2nd, Williams D, Hajnóczky G, Wallace DC.

Nat Commun. 2015 Feb 17;6:6259. doi: 10.1038/ncomms7259.

18.

Improved methodical approach for quantitative BRET analysis of G Protein Coupled Receptor dimerization.

Szalai B, Hoffmann P, Prokop S, Erdélyi L, Várnai P, Hunyady L.

PLoS One. 2014 Oct 17;9(10):e109503. doi: 10.1371/journal.pone.0109503. eCollection 2014. Erratum in: PLoS One. 2016;11(5):e0156824.

19.

Back to the future with the AGP-Ca2+ flux capacitor.

Lamport DT, Varnai P, Seal CE.

Ann Bot. 2014 Oct;114(6):1069-85. doi: 10.1093/aob/mcu161. Epub 2014 Aug 19. Review.

20.

Distribution and apoptotic function of outer membrane proteins depend on mitochondrial fusion.

Weaver D, Eisner V, Liu X, Várnai P, Hunyady L, Gross A, Hajnóczky G.

Mol Cell. 2014 Jun 5;54(5):870-8. doi: 10.1016/j.molcel.2014.03.048. Epub 2014 May 8.

21.

Altered agonist sensitivity of a mutant v2 receptor suggests a novel therapeutic strategy for nephrogenic diabetes insipidus.

Erdélyi LS, Balla A, Patócs A, Tóth M, Várnai P, Hunyady L.

Mol Endocrinol. 2014 May;28(5):634-43. doi: 10.1210/me.2013-1424. Epub 2014 Mar 14.

22.

Periplasmic arabinogalactan glycoproteins act as a calcium capacitor that regulates plant growth and development.

Lamport DT, Várnai P.

New Phytol. 2013 Jan;197(1):58-64. doi: 10.1111/nph.12005. Epub 2012 Oct 29.

23.

Switch from ER-mitochondrial to SR-mitochondrial calcium coupling during muscle differentiation.

Yi M, Weaver D, Eisner V, Várnai P, Hunyady L, Ma J, Csordás G, Hajnóczky G.

Cell Calcium. 2012 Nov;52(5):355-65. doi: 10.1016/j.ceca.2012.05.012. Epub 2012 Jul 10.

24.

Allosteric interactions within the AT₁ angiotensin receptor homodimer: role of the conserved DRY motif.

Szalai B, Barkai L, Turu G, Szidonya L, Várnai P, Hunyady L.

Biochem Pharmacol. 2012 Aug 15;84(4):477-85. doi: 10.1016/j.bcp.2012.04.014. Epub 2012 May 8.

PMID:
22579851
25.

Acute depletion of plasma membrane phosphatidylinositol 4,5-bisphosphate impairs specific steps in endocytosis of the G-protein-coupled receptor.

Tóth DJ, Tóth JT, Gulyás G, Balla A, Balla T, Hunyady L, Várnai P.

J Cell Sci. 2012 May 1;125(Pt 9):2185-97. doi: 10.1242/jcs.097279. Epub 2012 Feb 22.

26.

Mapping of the localization of type 1 angiotensin receptor in membrane microdomains using bioluminescence resonance energy transfer-based sensors.

Balla A, Tóth DJ, Soltész-Katona E, Szakadáti G, Erdélyi LS, Várnai P, Hunyady L.

J Biol Chem. 2012 Mar 16;287(12):9090-9. doi: 10.1074/jbc.M111.293944. Epub 2012 Jan 30.

27.

Calcium transport across the inner mitochondrial membrane: molecular mechanisms and pharmacology.

Csordás G, Várnai P, Golenár T, Sheu SS, Hajnóczky G.

Mol Cell Endocrinol. 2012 Apr 28;353(1-2):109-13. doi: 10.1016/j.mce.2011.11.011. Epub 2011 Nov 22. Review.

28.

The effect of OPA1 on mitochondrial Ca²⁺ signaling.

Fülöp L, Szanda G, Enyedi B, Várnai P, Spät A.

PLoS One. 2011;6(9):e25199. doi: 10.1371/journal.pone.0025199. Epub 2011 Sep 29.

29.

Cytosine, the double helix and DNA self-assembly.

Timsit Y, Varnai P.

J Mol Recognit. 2011 Mar-Apr;24(2):137-8. doi: 10.1002/jmr.1082.

PMID:
21360605
30.

Activation of STIM1-Orai1 involves an intramolecular switching mechanism.

Korzeniowski MK, Manjarrés IM, Varnai P, Balla T.

Sci Signal. 2010 Nov 16;3(148):ra82. doi: 10.1126/scisignal.2001122.

31.

Demonstration of angiotensin II-induced Ras activation in the trans-Golgi network and endoplasmic reticulum using bioluminescence resonance energy transfer-based biosensors.

Balla A, Erdélyi LS, Soltész-Katona E, Balla T, Várnai P, Hunyady L.

J Biol Chem. 2011 Feb 18;286(7):5319-27. doi: 10.1074/jbc.M110.176933. Epub 2010 Nov 8.

32.

Relating underrepresented genomic DNA patterns and tiRNAs: the rule behind the observation and beyond.

Cserzo M, Turu G, Varnai P, Hunyady L.

Biol Direct. 2010 Sep 22;5:56. doi: 10.1186/1745-6150-5-56.

33.

Imaging interorganelle contacts and local calcium dynamics at the ER-mitochondrial interface.

Csordás G, Várnai P, Golenár T, Roy S, Purkins G, Schneider TG, Balla T, Hajnóczky G.

Mol Cell. 2010 Jul 9;39(1):121-32. doi: 10.1016/j.molcel.2010.06.029.

34.

Plant O-hydroxyproline arabinogalactans are composed of repeating trigalactosyl subunits with short bifurcated side chains.

Tan L, Varnai P, Lamport DT, Yuan C, Xu J, Qiu F, Kieliszewski MJ.

J Biol Chem. 2010 Aug 6;285(32):24575-83. doi: 10.1074/jbc.M109.100149. Epub 2010 May 20.

35.

Acute manipulation of Golgi phosphoinositides to assess their importance in cellular trafficking and signaling.

Szentpetery Z, Várnai P, Balla T.

Proc Natl Acad Sci U S A. 2010 May 4;107(18):8225-30. doi: 10.1073/pnas.1000157107. Epub 2010 Apr 19.

36.

Differential stability of DNA crossovers in solution mediated by divalent cations.

Várnai P, Timsit Y.

Nucleic Acids Res. 2010 Jul;38(12):4163-72. doi: 10.1093/nar/gkq150. Epub 2010 Mar 9.

37.

Helical chirality: a link between local interactions and global topology in DNA.

Timsit Y, Várnai P.

PLoS One. 2010 Feb 19;5(2):e9326. doi: 10.1371/journal.pone.0009326.

38.

Molecular simulation of conformational transitions in biomolecules using a combination of structure-based potential and empirical valence bond theory.

de Marco G, Várnai P.

Phys Chem Chem Phys. 2009 Dec 7;11(45):10694-700. doi: 10.1039/b917109f. Epub 2009 Oct 1.

PMID:
20145813
39.

Redox state of the endoplasmic reticulum is controlled by Ero1L-alpha and intraluminal calcium.

Enyedi B, Várnai P, Geiszt M.

Antioxid Redox Signal. 2010 Sep 15;13(6):721-9. doi: 10.1089/ars.2009.2880.

PMID:
20095866
40.

Determination of the free energy landscape of alpha-synuclein using spin label nuclear magnetic resonance measurements.

Allison JR, Varnai P, Dobson CM, Vendruscolo M.

J Am Chem Soc. 2009 Dec 30;131(51):18314-26. doi: 10.1021/ja904716h.

PMID:
20028147
41.

Calcium entry is regulated by Zn2+ in relation to extracellular ionic environment in human airway epithelial cells.

Hargitai D, Pataki A, Raffai G, Füzi M, Dankó T, Csernoch L, Várnai P, Szigeti GP, Zsembery A.

Respir Physiol Neurobiol. 2010 Jan 31;170(1):67-75. doi: 10.1016/j.resp.2009.12.001. Epub 2009 Dec 6.

PMID:
19995619
42.

Reconciling the lock-and-key and dynamic views of canonical serine protease inhibitor action.

Gáspári Z, Várnai P, Szappanos B, Perczel A.

FEBS Lett. 2010 Jan 4;584(1):203-6. doi: 10.1016/j.febslet.2009.11.058.

43.

A G-rich sequence within the c-kit oncogene promoter forms a parallel G-quadruplex having asymmetric G-tetrad dynamics.

Hsu ST, Varnai P, Bugaut A, Reszka AP, Neidle S, Balasubramanian S.

J Am Chem Soc. 2009 Sep 23;131(37):13399-409. doi: 10.1021/ja904007p.

44.

Dependence of STIM1/Orai1-mediated calcium entry on plasma membrane phosphoinositides.

Korzeniowski MK, Popovic MA, Szentpetery Z, Varnai P, Stojilkovic SS, Balla T.

J Biol Chem. 2009 Jul 31;284(31):21027-35. doi: 10.1074/jbc.M109.012252. Epub 2009 May 29.

45.

Mechanisms of angiotensin II-mediated regulation of aldosterone synthase expression in H295R human adrenocortical and rat adrenal glomerulosa cells.

Szekeres M, Turu G, Orient A, Szalai B, Süpeki K, Cserzo M, Várnai P, Hunyady L.

Mol Cell Endocrinol. 2009 Apr 29;302(2):244-53.

PMID:
19418629
46.

Paracrine transactivation of the CB1 cannabinoid receptor by AT1 angiotensin and other Gq/11 protein-coupled receptors.

Turu G, Várnai P, Gyombolai P, Szidonya L, Offertaler L, Bagdy G, Kunos G, Hunyady L.

J Biol Chem. 2009 Jun 19;284(25):16914-21. doi: 10.1074/jbc.M109.003681. Epub 2009 Apr 7.

47.

Visualization of cellular phosphoinositide pools with GFP-fused protein-domains.

Balla T, Várnai P.

Curr Protoc Cell Biol. 2009 Mar;Chapter 24:Unit 24.4. doi: 10.1002/0471143030.cb2404s42.

48.

STIM and Orai: the long-awaited constituents of store-operated calcium entry.

Várnai P, Hunyady L, Balla T.

Trends Pharmacol Sci. 2009 Mar;30(3):118-28. doi: 10.1016/j.tips.2008.11.005. Epub 2009 Jan 31. Review.

49.

Live cell imaging of phosphoinositides with expressed inositide binding protein domains.

Várnai P, Balla T.

Methods. 2008 Nov;46(3):167-76. doi: 10.1016/j.ymeth.2008.09.019. Epub 2008 Oct 16.

50.

Determination of the transition state ensemble for the folding of ubiquitin from a combination of Phi and Psi analyses.

Várnai P, Dobson CM, Vendruscolo M.

J Mol Biol. 2008 Mar 21;377(2):575-88. doi: 10.1016/j.jmb.2008.01.012. Epub 2008 Jan 15.

PMID:
18262544

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