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Items: 39

1.

On the functional characterization of lytic polysaccharide monooxygenases (LPMOs).

Eijsink VGH, Petrovic D, Forsberg Z, Mekasha S, Røhr ÅK, Várnai A, Bissaro B, Vaaje-Kolstad G.

Biotechnol Biofuels. 2019 Mar 19;12:58. doi: 10.1186/s13068-019-1392-0. eCollection 2019. Review.

2.

Fungal PQQ-dependent dehydrogenases and their potential in biocatalysis.

Takeda K, Umezawa K, Várnai A, Eijsink VG, Igarashi K, Yoshida M, Nakamura N.

Curr Opin Chem Biol. 2019 Apr;49:113-121. doi: 10.1016/j.cbpa.2018.12.001. Epub 2018 Dec 20. Review.

PMID:
30580186
3.

pH-Dependent Relationship between Catalytic Activity and Hydrogen Peroxide Production Shown via Characterization of a Lytic Polysaccharide Monooxygenase from Gloeophyllum trabeum.

Hegnar OA, Petrovic DM, Bissaro B, Alfredsen G, Várnai A, Eijsink VGH.

Appl Environ Microbiol. 2019 Feb 20;85(5). pii: e02612-18. doi: 10.1128/AEM.02612-18. Print 2019 Mar 1.

PMID:
30578267
4.

Oxidoreductases and Reactive Oxygen Species in Conversion of Lignocellulosic Biomass.

Bissaro B, Várnai A, Røhr ÅK, Eijsink VGH.

Microbiol Mol Biol Rev. 2018 Sep 26;82(4). pii: e00029-18. doi: 10.1128/MMBR.00029-18. Print 2018 Dec. Review.

PMID:
30257993
5.

Functional characterization of a lytic polysaccharide monooxygenase from the thermophilic fungus Myceliophthora thermophila.

Kadowaki MAS, Várnai A, Jameson JK, T Leite AE, Costa-Filho AJ, Kumagai PS, Prade RA, Polikarpov I, Eijsink VGH.

PLoS One. 2018 Aug 20;13(8):e0202148. doi: 10.1371/journal.pone.0202148. eCollection 2018.

6.

Methylation of the N-terminal histidine protects a lytic polysaccharide monooxygenase from auto-oxidative inactivation.

Petrović DM, Bissaro B, Chylenski P, Skaugen M, Sørlie M, Jensen MS, Aachmann FL, Courtade G, Várnai A, Eijsink VGH.

Protein Sci. 2018 Sep;27(9):1636-1650. doi: 10.1002/pro.3451.

PMID:
29971843
7.

The Pyrroloquinoline-Quinone-Dependent Pyranose Dehydrogenase from Coprinopsis cinerea Drives Lytic Polysaccharide Monooxygenase Action.

Várnai A, Umezawa K, Yoshida M, Eijsink VGH.

Appl Environ Microbiol. 2018 May 17;84(11). pii: e00156-18. doi: 10.1128/AEM.00156-18. Print 2018 Jun 1.

8.

Outer membrane vesicles from Fibrobacter succinogenes S85 contain an array of carbohydrate-active enzymes with versatile polysaccharide-degrading capacity.

Arntzen MØ, Várnai A, Mackie RI, Eijsink VGH, Pope PB.

Environ Microbiol. 2017 Jul;19(7):2701-2714. doi: 10.1111/1462-2920.13770. Epub 2017 May 29.

PMID:
28447389
9.

Development of minimal enzyme cocktails for hydrolysis of sulfite-pulped lignocellulosic biomass.

Chylenski P, Forsberg Z, Ståhlberg J, Várnai A, Lersch M, Bengtsson O, Sæbø S, Horn SJ, Eijsink VGH.

J Biotechnol. 2017 Mar 20;246:16-23. doi: 10.1016/j.jbiotec.2017.02.009. Epub 2017 Feb 17.

PMID:
28219736
10.

A Lytic Polysaccharide Monooxygenase with Broad Xyloglucan Specificity from the Brown-Rot Fungus Gloeophyllum trabeum and Its Action on Cellulose-Xyloglucan Complexes.

Kojima Y, Várnai A, Ishida T, Sunagawa N, Petrovic DM, Igarashi K, Jellison J, Goodell B, Alfredsen G, Westereng B, Eijsink VG, Yoshida M.

Appl Environ Microbiol. 2016 Oct 27;82(22):6557-6572. Print 2016 Nov 15.

11.

FgLPMO9A from Fusarium graminearum cleaves xyloglucan independently of the backbone substitution pattern.

Nekiunaite L, Petrović DM, Westereng B, Vaaje-Kolstad G, Hachem MA, Várnai A, Eijsink VG.

FEBS Lett. 2016 Oct;590(19):3346-3356. doi: 10.1002/1873-3468.12385. Epub 2016 Sep 18.

12.

Comparison of fungal carbohydrate esterases of family CE16 on artificial and natural substrates.

Puchart V, Agger JW, Berrin JG, Várnai A, Westereng B, Biely P.

J Biotechnol. 2016 Sep 10;233:228-36. doi: 10.1016/j.jbiotec.2016.07.003. Epub 2016 Jul 18.

PMID:
27439201
13.

Simultaneous analysis of C1 and C4 oxidized oligosaccharides, the products of lytic polysaccharide monooxygenases acting on cellulose.

Westereng B, Arntzen MØ, Aachmann FL, Várnai A, Eijsink VG, Agger JW.

J Chromatogr A. 2016 May 6;1445:46-54. doi: 10.1016/j.chroma.2016.03.064. Epub 2016 Mar 25.

PMID:
27059395
14.

Harnessing the potential of LPMO-containing cellulase cocktails poses new demands on processing conditions.

Müller G, Várnai A, Johansen KS, Eijsink VG, Horn SJ.

Biotechnol Biofuels. 2015 Nov 25;8:187. doi: 10.1186/s13068-015-0376-y. eCollection 2015.

15.

Structural and Functional Characterization of a Lytic Polysaccharide Monooxygenase with Broad Substrate Specificity.

Borisova AS, Isaksen T, Dimarogona M, Kognole AA, Mathiesen G, Várnai A, Røhr ÅK, Payne CM, Sørlie M, Sandgren M, Eijsink VG.

J Biol Chem. 2015 Sep 18;290(38):22955-69. doi: 10.1074/jbc.M115.660183. Epub 2015 Jul 15.

16.

Mechanisms of laccase-mediator treatments improving the enzymatic hydrolysis of pre-treated spruce.

Moilanen U, Kellock M, Várnai A, Andberg M, Viikari L.

Biotechnol Biofuels. 2014 Dec 24;7(1):177. doi: 10.1186/s13068-014-0177-8. eCollection 2014.

17.

Effects of enzymatic removal of plant cell wall acylation (acetylation, p-coumaroylation, and feruloylation) on accessibility of cellulose and xylan in natural (non-pretreated) sugar cane fractions.

Várnai A, Costa TH, Faulds CB, Milagres AM, Siika-Aho M, Ferraz A.

Biotechnol Biofuels. 2014 Oct 15;7(1):153. doi: 10.1186/s13068-014-0153-3. eCollection 2014.

18.

Carbohydrate-binding modules of fungal cellulases: occurrence in nature, function, and relevance in industrial biomass conversion.

Várnai A, Mäkelä MR, Djajadi DT, Rahikainen J, Hatakka A, Viikari L.

Adv Appl Microbiol. 2014;88:103-65. doi: 10.1016/B978-0-12-800260-5.00004-8. Review.

PMID:
24767427
19.

Expression of endoglucanases in Pichia pastoris under control of the GAP promoter.

Várnai A, Tang C, Bengtsson O, Atterton A, Mathiesen G, Eijsink VG.

Microb Cell Fact. 2014 Apr 18;13(1):57. doi: 10.1186/1475-2859-13-57.

20.

Discovery of LPMO activity on hemicelluloses shows the importance of oxidative processes in plant cell wall degradation.

Agger JW, Isaksen T, Várnai A, Vidal-Melgosa S, Willats WG, Ludwig R, Horn SJ, Eijsink VG, Westereng B.

Proc Natl Acad Sci U S A. 2014 Apr 29;111(17):6287-92. doi: 10.1073/pnas.1323629111. Epub 2014 Apr 14.

21.

Cellulases without carbohydrate-binding modules in high consistency ethanol production process.

Pakarinen A, Haven MO, Djajadi DT, Várnai A, Puranen T, Viikari L.

Biotechnol Biofuels. 2014 Feb 21;7(1):27. doi: 10.1186/1754-6834-7-27.

22.

The role of carbohydrate binding module (CBM) at high substrate consistency: comparison of Trichoderma reesei and Thermoascus aurantiacus Cel7A (CBHI) and Cel5A (EGII).

Le Costaouëc T, Pakarinen A, Várnai A, Puranen T, Viikari L.

Bioresour Technol. 2013 Sep;143:196-203. doi: 10.1016/j.biortech.2013.05.079. Epub 2013 May 28.

PMID:
23796604
23.

Carbohydrate-binding modules (CBMs) revisited: reduced amount of water counterbalances the need for CBMs.

Várnai A, Siika-Aho M, Viikari L.

Biotechnol Biofuels. 2013 Feb 26;6(1):30. doi: 10.1186/1754-6834-6-30.

24.

Xylan as limiting factor in enzymatic hydrolysis of nanocellulose.

Penttilä PA, Várnai A, Pere J, Tammelin T, Salmén L, Siika-aho M, Viikari L, Serimaa R.

Bioresour Technol. 2013 Feb;129:135-41. doi: 10.1016/j.biortech.2012.11.017. Epub 2012 Nov 19.

PMID:
23238342
25.

Synergistic action of xylanase and mannanase improves the total hydrolysis of softwood.

Várnai A, Huikko L, Pere J, Siika-Aho M, Viikari L.

Bioresour Technol. 2011 Oct;102(19):9096-104. doi: 10.1016/j.biortech.2011.06.059. Epub 2011 Jun 22.

PMID:
21757337
26.

Adsorption of monocomponent enzymes in enzyme mixture analyzed quantitatively during hydrolysis of lignocellulose substrates.

Várnai A, Viikari L, Marjamaa K, Siika-aho M.

Bioresour Technol. 2011 Jan;102(2):1220-7. doi: 10.1016/j.biortech.2010.07.120. Epub 2010 Aug 4.

PMID:
20736135
27.

Changes in submicrometer structure of enzymatically hydrolyzed microcrystalline cellulose.

Penttilä PA, Várnai A, Leppänen K, Peura M, Kallonen A, Jääskeläinen P, Lucenius J, Ruokolainen J, Siika-Aho M, Viikari L, Serimaa R.

Biomacromolecules. 2010 Apr 12;11(4):1111-7. doi: 10.1021/bm1001119.

PMID:
20329744
28.

Negative salt effect in an acid-base diode: Simulations and experiments.

Roszol L, Várnai A, Lorántfy B, Noszticzius Z, Wittmann M.

J Chem Phys. 2010 Feb 14;132(6):064902. doi: 10.1063/1.3292001.

PMID:
20151753
29.

A 7.5-year prospective study of longer than 18 months type-specific human papillomavirus persistence in a routine cytology-based cervical screening population of about 31,000 women in West Germany.

Kovács K, Varnai AD, Bollmann M, Bankfalvi A, Szendy M, Speich N, Schmitt C, Pajor L, Bollmann R, Hildenbrand R.

Eur J Cancer Prev. 2009 Aug;18(4):307-15. doi: 10.1097/CEJ.0b013e328324061a.

PMID:
19436214
30.

The prevalence and distribution of human papillomavirus genotypes in oral epithelial hyperplasia: proposal of a concept.

Varnai AD, Bollmann M, Bankfalvi A, Kovacs K, Heller H, Schmitt C, Volek J, Szendy M, Bollmann R, Hildenbrand R.

J Oral Pathol Med. 2009 Feb;38(2):181-7. doi: 10.1111/j.1600-0714.2008.00723.x. Epub 2008 Dec 26.

PMID:
19141061
31.

Prevalence and genotype distribution of multiple human papillomavirus infection in the uterine cervix: a 7.5-year longitudinal study in a routine cytology-based screening population in West Germany.

Kovács K, Varnai AD, Bollmann M, Bankfalvi A, Szendy M, Speich N, Schmitt C, Pajor L, Bollmann R.

J Med Virol. 2008 Oct;80(10):1814-23. doi: 10.1002/jmv.21282.

PMID:
18712836
32.

Predictive testing of early cervical pre-cancer by detecting human papillomavirus E6/E7 mRNA in cervical cytologies up to high-grade squamous intraepithelial lesions: diagnostic and prognostic implications.

Varnai AD, Bollmann M, Bankfalvi A, Speich N, Schmitt C, Griefingholt H, Kovács K, Klozoris C, Bollmann R.

Oncol Rep. 2008 Feb;19(2):457-65.

PMID:
18202795
33.

[Risk-adapted multimodal laboratory cervical screening---Pap test of the future?].

Bollmann R, Varnai AD, Bankfalvi A, Bollmann M.

Pathologe. 2007 Sep;28(5):334-8. German.

PMID:
17661045
34.

The spectrum of cervical diseases induced by low-risk and undefined-risk HPVS: implications for patient management.

Várnai AD, Bollmann M, Bánkfalvi A, Griefingholt H, Pfening N, Schmitt C, Pajor L, Bollmann R.

Anticancer Res. 2007 Jan-Feb;27(1B):563-70.

35.

Karyotype complexity and VH gene status in B-cell chronic lymphocytic leukemia.

Méhes G, Kovács G, Kajtár B, Lacza A, Várnai A, Losonczy H, Pajor L.

Haematologica. 2006 Oct;91(10):1430-1. Epub 2006 Sep 7.

36.

Detection of lymphatic invasion in early stage primary colorectal cancer with the monoclonal antibody D2-40.

Walgenbach-Bruenagel G, Tolba RH, Varnai AD, Bollmann M, Hirner A, Walgenbach KJ.

Eur Surg Res. 2006;38(5):438-44. Epub 2006 Aug 15.

PMID:
16912482
37.

Predicting treatment outcome in cervical diseases using liquid-based cytology, dynamic HPV genotyping and DNA cytometry.

Bollmann M, Várnai AD, Griefingholt H, Bánkfalvi A, Callenberg H, Speich N, Schmitt C, Bollmann R.

Anticancer Res. 2006 Mar-Apr;26(2B):1439-46.

38.

HPV in anal squamous cell carcinoma and anal intraepithelial neoplasia (AIN). Impact of HPV analysis of anal lesions on diagnosis and prognosis.

Varnai AD, Bollmann M, Griefingholt H, Speich N, Schmitt C, Bollmann R, Decker D.

Int J Colorectal Dis. 2006 Mar;21(2):135-42. Epub 2005 Apr 29.

PMID:
15864603
39.

Loss of E-cadherin expression in melanoma cells involves up-regulation of the transcriptional repressor Snail.

Poser I, Domínguez D, de Herreros AG, Varnai A, Buettner R, Bosserhoff AK.

J Biol Chem. 2001 Jul 6;276(27):24661-6. Epub 2001 Apr 25.

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