Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 26

1.

Targeting redox regulation to treat substance use disorder using N-acetylcysteine.

Womersley JS, Townsend DM, Kalivas PW, Uys JD.

Eur J Neurosci. 2018 Aug 24. doi: 10.1111/ejn.14130. [Epub ahead of print] Review.

PMID:
30144182
2.

Methamphetamine Induces Dopamine Release in the Nucleus Accumbens Through a Sigma Receptor-Mediated Pathway.

Hedges DM, Obray JD, Yorgason JT, Jang EY, Weerasekara VK, Uys JD, Bellinger FP, Steffensen SC.

Neuropsychopharmacology. 2018 May;43(6):1405-1414. doi: 10.1038/npp.2017.291. Epub 2017 Nov 29.

PMID:
29185481
3.

Novel sphingosine kinase-1 inhibitor, LCL351, reduces immune responses in murine DSS-induced colitis.

Pulkoski-Gross MJ, Uys JD, Orr-Gandy KA, Coant N, Bialkowska AB, Szulc ZM, Bai A, Bielawska A, Townsend DM, Hannun YA, Obeid LM, Snider AJ.

Prostaglandins Other Lipid Mediat. 2017 May;130:47-56. doi: 10.1016/j.prostaglandins.2017.03.006. Epub 2017 Apr 2.

4.

Orbitofrontal Neuroadaptations and Cross-Species Synaptic Biomarkers in Heavy-Drinking Macaques.

Nimitvilai S, Uys JD, Woodward JJ, Randall PK, Ball LE, Williams RW, Jones BC, Lu L, Grant KA, Mulholland PJ.

J Neurosci. 2017 Mar 29;37(13):3646-3660. doi: 10.1523/JNEUROSCI.0133-17.2017. Epub 2017 Mar 7.

5.

S-Glutathionylation and Redox Protein Signaling in Drug Addiction.

Womersley JS, Uys JD.

Prog Mol Biol Transl Sci. 2016;137:87-121. doi: 10.1016/bs.pmbts.2015.10.001. Epub 2015 Oct 31.

6.

Chronic intermittent ethanol exposure and withdrawal leads to adaptations in nucleus accumbens core postsynaptic density proteome and dendritic spines.

Uys JD, McGuier NS, Gass JT, Griffin WC 3rd, Ball LE, Mulholland PJ.

Addict Biol. 2016 May;21(3):560-74. doi: 10.1111/adb.12238. Epub 2015 Mar 17.

7.

N-acetyl-L-cysteine sensitizes pancreatic cancers to gemcitabine by targeting the NFκB pathway.

Qanungo S, Uys JD, Manevich Y, Distler AM, Shaner B, Hill EG, Mieyal JJ, Lemasters JJ, Townsend DM, Nieminen AL.

Biomed Pharmacother. 2014 Sep;68(7):855-64. doi: 10.1016/j.biopha.2014.08.007. Epub 2014 Aug 28.

8.

Glutathione and redox signaling in substance abuse.

Uys JD, Mulholland PJ, Townsend DM.

Biomed Pharmacother. 2014 Jul;68(6):799-807. doi: 10.1016/j.biopha.2014.06.001. Epub 2014 Jun 24. Review.

9.

Ablation of the ATP-binding cassette transporter, Abca2 modifies response to estrogen-based therapies.

Mack JT, Brown CB, Garrett TE, Uys JD, Townsend DM, Tew KD.

Biomed Pharmacother. 2012 Sep;66(6):403-8. doi: 10.1016/j.biopha.2012.06.007. Epub 2012 Jul 2.

10.

S-glutathionylated serine proteinase inhibitors as plasma biomarkers in assessing response to redox-modulating drugs.

Grek CL, Townsend DM, Uys JD, Manevich Y, Coker WJ 3rd, Pazoles CJ, Tew KD.

Cancer Res. 2012 May 1;72(9):2383-93. doi: 10.1158/0008-5472.CAN-11-4088. Epub 2012 Mar 8.

11.

Cocaine-induced adaptations in cellular redox balance contributes to enduring behavioral plasticity.

Uys JD, Knackstedt L, Hurt P, Tew KD, Manevich Y, Hutchens S, Townsend DM, Kalivas PW.

Neuropsychopharmacology. 2011 Nov;36(12):2551-60. doi: 10.1038/npp.2011.143. Epub 2011 Jul 27.

12.

AKAP signaling in reinstated cocaine seeking revealed by iTRAQ proteomic analysis.

Reissner KJ, Uys JD, Schwacke JH, Comte-Walters S, Rutherford-Bethard JL, Dunn TE, Blumer JB, Schey KL, Kalivas PW.

J Neurosci. 2011 Apr 13;31(15):5648-58. doi: 10.1523/JNEUROSCI.3452-10.2011.

13.

Nitrosative stress-induced S-glutathionylation of protein disulfide isomerase.

Uys JD, Xiong Y, Townsend DM.

Methods Enzymol. 2011;490:321-32. doi: 10.1016/B978-0-12-385114-7.00018-0.

14.

S-glutathionylation: from molecular mechanisms to health outcomes.

Xiong Y, Uys JD, Tew KD, Townsend DM.

Antioxid Redox Signal. 2011 Jul 1;15(1):233-70. doi: 10.1089/ars.2010.3540. Epub 2011 May 25. Review.

15.

Glutamatergic neuroplasticity in cocaine addiction.

Uys JD, Reissner KJ.

Prog Mol Biol Transl Sci. 2011;98:367-400. doi: 10.1016/B978-0-12-385506-0.00009-0. Review.

PMID:
21199777
16.

Preclinical pharmacokinetic analysis of NOV-002, a glutathione disulfide mimetic.

Uys JD, Manevich Y, Devane LC, He L, Garret TE, Pazoles CJ, Tew KD, Townsend DM.

Biomed Pharmacother. 2010 Sep;64(7):493-8. doi: 10.1016/j.biopha.2010.01.003. Epub 2010 Feb 24.

17.

Matrix-assisted laser desorption/ionization tissue profiling of secretoneurin in the nucleus accumbens shell from cocaine-sensitized rats.

Uys JD, Grey AC, Wiggins A, Schwacke JH, Schey KL, Kalivas PW.

J Mass Spectrom. 2010 Jan;45(1):97-103. doi: 10.1002/jms.1697.

18.

Glutamate: the new frontier in pharmacotherapy for cocaine addiction.

Uys JD, LaLumiere RT.

CNS Neurol Disord Drug Targets. 2008 Nov;7(5):482-91. Review.

PMID:
19128205
19.

Large scale hippocampal cellular distress may explain the behavioral consequences of repetitive traumatic experiences--a proteomic approach.

Uys JD, Hattingh SM, Stein DJ, Daniels WM.

Neurochem Res. 2008 Sep;33(9):1724-34. doi: 10.1007/s11064-008-9615-y. Epub 2008 Feb 29.

PMID:
18307038
20.

Early maternal separation alters the response to traumatization: resulting in increased levels of hippocampal neurotrophic factors.

Faure J, Uys JD, Marais L, Stein DJ, Daniels WM.

Metab Brain Dis. 2007 Jun;22(2):183-95. Epub 2007 Apr 29.

PMID:
17468977
21.

Developmental trauma is associated with behavioral hyperarousal, altered HPA axis activity, and decreased hippocampal neurotrophin expression in the adult rat.

Uys JD, Marais L, Faure J, Prevoo D, Swart P, Mohammed AH, Stein DJ, Daniels WM.

Ann N Y Acad Sci. 2006 Jul;1071:542-6.

PMID:
16891615
22.

Neuroproteomics: relevance to anxiety disorders.

Uys JD, Stein DJ, Daniels WM.

Curr Psychiatry Rep. 2006 Aug;8(4):286-90. Review.

PMID:
16879792
23.

Early maternal separation followed by later stressors leads to dysregulation of the HPA-axis and increases in hippocampal NGF and NT-3 levels in a rat model.

Faure J, Uys JD, Marais L, Stein DJ, Daniels WM.

Metab Brain Dis. 2006 Sep;21(2-3):181-88. Epub 2006 Jul 19.

PMID:
16850259
24.

Early life trauma decreases glucocorticoid receptors in rat dentate gyrus upon adult re-stress: reversal by escitalopram.

Uys JD, Muller CJ, Marais L, Harvey BH, Stein DJ, Daniels WM.

Neuroscience. 2006;137(2):619-25. Epub 2005 Nov 28.

PMID:
16310967
26.

Animal models of anxiety disorders.

Uys JD, Stein DJ, Daniels WM, Harvey BH.

Curr Psychiatry Rep. 2003 Aug;5(4):274-81. Review.

PMID:
12857530

Supplemental Content

Support Center