Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 693

1.

Nipah shell disorder, modes of infection, and virulence.

Goh GK, Dunker AK, Foster JA, Uversky VN.

Microb Pathog. 2020 Jan 12;141:103976. doi: 10.1016/j.micpath.2020.103976. [Epub ahead of print]

PMID:
31940461
2.

Nucleation-dependent amyloid fibrillation of human GRASP55 in aqueous solution.

Reddy ST, Uversky VN, Costa-Filho AJ.

Eur Biophys J. 2020 Jan 8. doi: 10.1007/s00249-019-01419-7. [Epub ahead of print]

PMID:
31915857
3.

Liquid-liquid phase separation and fibrillation of the prion protein modulated by a high-affinity DNA aptamer.

Matos CO, Passos YM, do Amaral MJ, Macedo B, Tempone MH, Bezerra OCL, Moraes MO, Almeida MS, Weber G, Missailidis S, Silva JL, Uversky VN, Pinheiro AS, Cordeiro Y.

FASEB J. 2020 Jan;34(1):365-385. doi: 10.1096/fj.201901897R. Epub 2019 Nov 22.

PMID:
31914616
4.

Granulins modulate liquid-liquid phase separation and aggregation of prion-like C-terminal domain of the neurodegeneration-associated protein TDP-43.

Bhopatkar AA, Uversky VN, Rangachari V.

J Biol Chem. 2020 Jan 6. pii: jbc.RA119.011501. doi: 10.1074/jbc.RA119.011501. [Epub ahead of print]

5.

Intrinsic Disorder-Based Design of Stable Globular Proteins.

Nagibina GS, Glukhova KA, Uversky VN, Melnik TN, Melnik BS.

Biomolecules. 2019 Dec 30;10(1). pii: E64. doi: 10.3390/biom10010064.

6.

Epitope region identification challenges of intrinsically disordered proteins in neurodegenerative diseases: Secondary structure dependence of α-synuclein on simulation techniques and force field parameters.

Mandaci SY, Caliskan M, Sariaslan MF, Uversky VN, Coskuner-Weber O.

Chem Biol Drug Des. 2020 Jan 6. doi: 10.1111/cbdd.13662. [Epub ahead of print]

PMID:
31903719
7.

The dark side of Alzheimer's disease: unstructured biology of proteins from the amyloid cascade signaling pathway.

Gadhave K, Gehi BR, Kumar P, Xue B, Uversky VN, Giri R.

Cell Mol Life Sci. 2020 Jan 2. doi: 10.1007/s00018-019-03414-9. [Epub ahead of print]

PMID:
31894361
8.

Life in Phases: Intra- and Inter- Molecular Phase Transitions in Protein Solutions.

Uversky VN, Finkelstein AV.

Biomolecules. 2019 Dec 8;9(12). pii: E842. doi: 10.3390/biom9120842. Review.

9.

Evolutionary Analyses of Sequence and Structure Space Unravel the Structural Facets of SOD1.

Chowdhury S, Sanyal D, Sen S, Uversky VN, Maulik U, Chattopadhyay K.

Biomolecules. 2019 Dec 4;9(12). pii: E826. doi: 10.3390/biom9120826.

10.

Rational discovery of antimetastatic agents targeting the intrinsically disordered region of MBD2.

Kim MY, Na I, Kim JS, Son SH, Choi S, Lee SE, Kim JH, Jang K, Alterovitz G, Chen Y, van der Vaart A, Won HS, Uversky VN, Kim CG.

Sci Adv. 2019 Nov 20;5(11):eaav9810. doi: 10.1126/sciadv.aav9810. eCollection 2019 Nov.

11.

Many-to-one binding by intrinsically disordered protein regions.

Alterovitz WL, Faraggi E, Oldfield CJ, Meng J, Xue B, Huang F, Romero P, Kloczkowski A, Uversky VN, Dunker AK.

Pac Symp Biocomput. 2020;25:159-170.

12.

Characterization of an Extensive Interface on Vitronectin for Binding to Plasminogen Activator Inhibitor-1: Adoption of Structure in an Intrinsically Disordered Region.

Puster LO, Stanley CB, Uversky VN, Curtis JE, Krueger S, Chu Y, Peterson CB.

Biochemistry. 2019 Dec 24;58(51):5117-5134. doi: 10.1021/acs.biochem.9b00605. Epub 2019 Dec 16.

PMID:
31793295
13.

Comprehensive analysis of the molecular docking of small molecule inhibitors to the Aβ1-40 peptide and its Osaka-mutant: insights into the molecular mechanisms of Aβ-peptide inhibition.

Salahuddin P, Khan RH, Uversky VN.

J Biomol Struct Dyn. 2019 Dec 9:1-31. doi: 10.1080/07391102.2019.1697367. [Epub ahead of print]

PMID:
31779527
14.

Expanding the understanding of the heterogeneous nature of melanoma with bioinformatics and disorder-based proteomics.

Djulbegovic MB, Uversky VN.

Int J Biol Macromol. 2019 Nov 16. pii: S0141-8130(19)35074-3. doi: 10.1016/j.ijbiomac.2019.10.139. [Epub ahead of print] Review.

PMID:
31743721
15.

Chemical complementarity between immune receptor CDR3s and IDH1 mutants correlates with increased survival for lower grade glioma.

Chobrutskiy BI, Yeagley M, Tipping P, Zaman S, Diviney A, Patel DN, Falasiri S, Uversky VN, Blanck G.

Oncogene. 2019 Nov 18. doi: 10.1038/s41388-019-1101-2. [Epub ahead of print]

PMID:
31740784
16.

Understanding the penetrance of intrinsic protein disorder in rotavirus proteome.

Kumar D, Singh A, Kumar P, Uversky VN, Rao CD, Giri R.

Int J Biol Macromol. 2019 Nov 15. pii: S0141-8130(19)35020-2. doi: 10.1016/j.ijbiomac.2019.09.166. [Epub ahead of print]

PMID:
31739058
17.

Folding perspectives of an intrinsically disordered transactivation domain and its single mutation breaking the folding propensity.

Sharma N, Fonin AV, Shpironok OG, Silonov SA, Turoverov KK, Uversky VN, Kuznetsova IM, Giri R.

Int J Biol Macromol. 2019 Nov 13. pii: S0141-8130(19)34479-4. doi: 10.1016/j.ijbiomac.2019.11.111. [Epub ahead of print]

PMID:
31733244
18.

Zika and Flavivirus Shell Disorder: Virulence and Fetal Morbidity.

Goh GK, Dunker AK, Foster JA, Uversky VN.

Biomolecules. 2019 Nov 6;9(11). pii: E710. doi: 10.3390/biom9110710.

19.

Targeting the NTPase site of Zika virus NS3 helicase for inhibitor discovery.

Kumar D, Aarthy M, Kumar P, Singh SK, Uversky VN, Giri R.

J Biomol Struct Dyn. 2019 Nov 14:1-11. doi: 10.1080/07391102.2019.1689851. [Epub ahead of print]

PMID:
31690231
20.

Development of a MEL Cell-Derived Allograft Mouse Model for Cancer Research.

Kim MY, Choi S, Lee SE, Kim JS, Son SH, Lim YS, Kim BJ, Ryu BY, Uversky VN, Lee YJ, Kim CG.

Cancers (Basel). 2019 Nov 1;11(11). pii: E1707. doi: 10.3390/cancers11111707.

21.

Biophysical Elucidation of Amyloid Fibrillation Inhibition and Prevention of Secondary Nucleation by Cholic Acid: An Unexplored Function of Cholic Acid.

Majid N, Siddiqi MK, Khan AN, Shabnam S, Malik S, Alam A, Uversky VN, Khan RH.

ACS Chem Neurosci. 2019 Nov 20;10(11):4704-4715. doi: 10.1021/acschemneuro.9b00482. Epub 2019 Oct 29.

PMID:
31661243
22.

Intrinsic Disorder of the BAF Complex: Roles in Chromatin Remodeling and Disease Development.

El Hadidy N, Uversky VN.

Int J Mol Sci. 2019 Oct 23;20(21). pii: E5260. doi: 10.3390/ijms20215260.

23.

Small Heat Shock Proteins, Big Impact on Protein Aggregation in Neurodegenerative Disease.

Webster JM, Darling AL, Uversky VN, Blair LJ.

Front Pharmacol. 2019 Sep 18;10:1047. doi: 10.3389/fphar.2019.01047. eCollection 2019. Review.

24.

Modulating Insulin Fibrillation Using Engineered B-Chains with Mutated C-Termini.

Akbarian M, Yousefi R, Moosavi-Movahedi AA, Ahmad A, Uversky VN.

Biophys J. 2019 Nov 5;117(9):1626-1641. doi: 10.1016/j.bpj.2019.09.022. Epub 2019 Sep 23.

PMID:
31607389
25.

Single-cell RNA-Seq: a next generation sequencing tool for a high-resolution view of the individual cell.

Stevenson K, Uversky VN.

J Biomol Struct Dyn. 2019 Sep 15:1-6. doi: 10.1080/07391102.2019.1659859. [Epub ahead of print]

PMID:
31524088
26.

Intrinsically disordered proteins in various hypotheses on the pathogenesis of Alzheimer's and Parkinson's diseases.

Coskuner O, Uversky VN.

Prog Mol Biol Transl Sci. 2019;166:145-223. doi: 10.1016/bs.pmbts.2019.05.007. Epub 2019 Jul 19.

PMID:
31521231
27.

Protein intrinsic disorder and structure-function continuum.

Uversky VN.

Prog Mol Biol Transl Sci. 2019;166:1-17. doi: 10.1016/bs.pmbts.2019.05.003. Epub 2019 Jun 8.

PMID:
31521229
28.

Driving Forces of Liquid-Liquid Phase Separation in Biological Systems.

Zaslavsky BY, Ferreira LA, Uversky VN.

Biomolecules. 2019 Sep 10;9(9). pii: E473. doi: 10.3390/biom9090473.

29.
30.

Structural and functional analysis of "non-smelly" proteins.

Yan J, Cheng J, Kurgan L, Uversky VN.

Cell Mol Life Sci. 2019 Sep 5. doi: 10.1007/s00018-019-03292-1. [Epub ahead of print]

PMID:
31486849
31.

Structure Determination by Single-Particle Cryo-Electron Microscopy: Only the Sky (and Intrinsic Disorder) is the Limit.

Nwanochie E, Uversky VN.

Int J Mol Sci. 2019 Aug 27;20(17). pii: E4186. doi: 10.3390/ijms20174186. Review.

32.

Multi-functionality of proteins involved in GPCR and G protein signaling: making sense of structure-function continuum with intrinsic disorder-based proteoforms.

Fonin AV, Darling AL, Kuznetsova IM, Turoverov KK, Uversky VN.

Cell Mol Life Sci. 2019 Nov;76(22):4461-4492. doi: 10.1007/s00018-019-03276-1. Epub 2019 Aug 19. Review.

PMID:
31428838
33.

5-Aminolevulinate synthase catalysis: The catcher in heme biosynthesis.

Stojanovski BM, Hunter GA, Na I, Uversky VN, Jiang RHY, Ferreira GC.

Mol Genet Metab. 2019 Nov;128(3):178-189. doi: 10.1016/j.ymgme.2019.06.003. Epub 2019 Jun 13. Review.

PMID:
31345668
34.

An interplay of structure and intrinsic disorder in the functionality of peptidylarginine deiminases, a family of key autoimmunity-related enzymes.

Alghamdi M, Al Ghamdi KA, Khan RH, Uversky VN, Redwan EM.

Cell Mol Life Sci. 2019 Dec;76(23):4635-4662. doi: 10.1007/s00018-019-03237-8. Epub 2019 Jul 24. Review.

PMID:
31342121
35.

Experimental Insight into the Structural and Functional Roles of the 'Black' and 'Gray' Clusters in Recoverin, a Calcium Binding Protein with Four EF-Hand Motifs.

Permyakov SE, Vologzhannikova AS, Nemashkalova EL, Kazakov AS, Denesyuk AI, Denessiouk K, Baksheeva VE, Zamyatnin AA Jr, Zernii EY, Uversky VN, Permyakov EA.

Molecules. 2019 Jul 8;24(13). pii: E2494. doi: 10.3390/molecules24132494.

36.

Analyzing aggregation propensities of clinically relevant PTEN mutants: a new culprit in pathogenesis of cancer and other PTENopathies.

Palumbo E, Zhao B, Xue B, Uversky VN, Davé V.

J Biomol Struct Dyn. 2019 Jun 22:1-14. doi: 10.1080/07391102.2019.1630005. [Epub ahead of print]

PMID:
31232187
37.

Can a retro-polypeptide fold into a globule?

Kutyshenko VP, Sharapov MG, Uversky VN.

J Biomol Struct Dyn. 2019 Jul 2:1-5. doi: 10.1080/07391102.2019.1635045. [Epub ahead of print]

PMID:
31232183
38.

Ferroptosis - An iron- and disorder-dependent programmed cell death.

Djulbegovic MB, Uversky VN.

Int J Biol Macromol. 2019 Aug 15;135:1052-1069. doi: 10.1016/j.ijbiomac.2019.05.221. Epub 2019 Jun 5. Review.

PMID:
31175900
39.

Codon selection reduces GC content bias in nucleic acids encoding for intrinsically disordered proteins.

Oldfield CJ, Peng Z, Uversky VN, Kurgan L.

Cell Mol Life Sci. 2020 Jan;77(1):149-160. doi: 10.1007/s00018-019-03166-6. Epub 2019 Jun 7.

PMID:
31175370
40.

Intrinsic Disorder-Based Emergence in Cellular Biology: Physiological and Pathological Liquid-Liquid Phase Transitions in Cells.

Darling AL, Zaslavsky BY, Uversky VN.

Polymers (Basel). 2019 Jun 4;11(6). pii: E990. doi: 10.3390/polym11060990. Review.

41.

The Structural and Functional Diversity of Intrinsically Disordered Regions in Transmembrane Proteins.

Appadurai R, Uversky VN, Srivastava A.

J Membr Biol. 2019 Oct;252(4-5):273-292. doi: 10.1007/s00232-019-00069-2. Epub 2019 May 28. Review.

PMID:
31139867
42.

Bioinformatics characterisation of the (mutated) proteins related to Andersen-Tawil syndrome.

Polanco C, Uversky VN, Márquez MF, Buhse T, Estrada MA, Huberman A.

Math Biosci Eng. 2019 Mar 22;16(4):2532-2548. doi: 10.3934/mbe.2019127.

43.

HIV Vaccine Mystery and Viral Shell Disorder.

Goh GK, Dunker AK, Foster JA, Uversky VN.

Biomolecules. 2019 May 8;9(5). pii: E178. doi: 10.3390/biom9050178. Review.

44.

Stochasticity of Biological Soft Matter: Emerging Concepts in Intrinsically Disordered Proteins and Biological Phase Separation.

Turoverov KK, Kuznetsova IM, Fonin AV, Darling AL, Zaslavsky BY, Uversky VN.

Trends Biochem Sci. 2019 Aug;44(8):716-728. doi: 10.1016/j.tibs.2019.03.005. Epub 2019 Apr 22. Review.

PMID:
31023505
45.

Network mapping of the conformational heterogeneity of SOD1 by deploying statistical cluster analysis of FTIR spectra.

Chowdhury S, Sen S, Banerjee A, Uversky VN, Maulik U, Chattopadhyay K.

Cell Mol Life Sci. 2019 Oct;76(20):4145-4154. doi: 10.1007/s00018-019-03108-2. Epub 2019 Apr 22.

PMID:
31011770
46.

Intrinsically Disordered Proteins in Chronic Diseases.

Kulkarni P, Uversky VN.

Biomolecules. 2019 Apr 11;9(4). pii: E147. doi: 10.3390/biom9040147.

47.

Synergistic Killing of Pathogenic Escherichia coli Using Camel Lactoferrin from Different Saudi Camel Clans and Various Antibiotics.

Almehdar HA, El-Baky NA, Alhaider AA, Almuhaideb SA, Alhaider AA, Albiheyri RS, Uversky VN, Redwan EM.

Protein J. 2019 Aug;38(4):479-496. doi: 10.1007/s10930-019-09828-5.

PMID:
30963371
48.

Analyzing the structural and functional roles of residues from the 'black' and 'gray' clusters of human S100P protein.

Permyakova ME, Permyakov SE, Kazakov AS, Denesyuk AI, Denessiouk K, Uversky VN, Permyakov EA.

Cell Calcium. 2019 Jun;80:46-55. doi: 10.1016/j.ceca.2019.03.008. Epub 2019 Mar 28.

PMID:
30953998
49.

Disorder in milk proteins: adipophilin and TIP47, important constituents of the milk fat globule membrane.

Redwan EM, Alkarim SA, El-Hanafy AA, Saad YM, Almehdar HA, Uversky VN.

J Biomol Struct Dyn. 2019 Mar 21:1-16. doi: 10.1080/07391102.2019.1592027. [Epub ahead of print]

PMID:
30896308
50.

Effect of Cu2+ and Zn2+ ions on human serum albumin interaction with plasma unsaturated fatty acids.

Nemashkalova EL, Permyakov EA, Uversky VN, Permyakov SE, Litus EA.

Int J Biol Macromol. 2019 Jun 15;131:505-509. doi: 10.1016/j.ijbiomac.2019.03.085. Epub 2019 Mar 14.

PMID:
30880051

Supplemental Content

Loading ...
Support Center