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Items: 18

1.

Design and use of Chikungunya virus replication templates utilizing mammalian and mosquito RNA polymerase I mediated transcription.

Utt A, Rausalu K, Jakobson M, Männik A, Alphey L, Fragkoudis R, Merits A.

J Virol. 2019 Jun 19. pii: JVI.00794-19. doi: 10.1128/JVI.00794-19. [Epub ahead of print]

PMID:
31217251
2.

Mutating chikungunya virus non-structural protein produces potent live-attenuated vaccine candidate.

Chan YH, Teo TH, Utt A, Tan JJ, Amrun SN, Abu Bakar F, Yee WX, Becht E, Lee CY, Lee B, Rajarethinam R, Newell E, Merits A, Carissimo G, Lum FM, Ng LF.

EMBO Mol Med. 2019 Jun;11(6). pii: e10092. doi: 10.15252/emmm.201810092.

3.

Structural insights into RNA recognition by the Chikungunya virus nsP2 helicase.

Law YS, Utt A, Tan YB, Zheng J, Wang S, Chen MW, Griffin PR, Merits A, Luo D.

Proc Natl Acad Sci U S A. 2019 May 7;116(19):9558-9567. doi: 10.1073/pnas.1900656116. Epub 2019 Apr 18.

PMID:
31000599
4.

Quality of Sleep in a Pediatric Hospital: A Descriptive Study Based on an Assessment of Interruptions, Perceptions, and the Environment.

Crawford S, Utt A, Beebe C, Armbruster R, Fisher A, Olney A, Sherman AK, Roberts C.

J Nurs Adm. 2019 May;49(5):273-279. doi: 10.1097/NNA.0000000000000750.

PMID:
30973430
5.

ADP-ribosyl-binding and hydrolase activities of the alphavirus nsP3 macrodomain are critical for initiation of virus replication.

Abraham R, Hauer D, McPherson RL, Utt A, Kirby IT, Cohen MS, Merits A, Leung AKL, Griffin DE.

Proc Natl Acad Sci U S A. 2018 Oct 30;115(44):E10457-E10466. doi: 10.1073/pnas.1812130115. Epub 2018 Oct 15.

6.

Decreased Virulence of Ross River Virus Harboring a Mutation in the First Cleavage Site of Nonstructural Polyprotein Is Caused by a Novel Mechanism Leading to Increased Production of Interferon-Inducing RNAs.

Liu X, Mutso M, Utt A, Lepland A, Herrero LJ, Taylor A, Bettadapura J, Rudd PA, Merits A, Mahalingam S.

MBio. 2018 Aug 21;9(4). pii: e00044-18. doi: 10.1128/mBio.00044-18.

7.

A Chikungunya Virus trans-Replicase System Reveals the Importance of Delayed Nonstructural Polyprotein Processing for Efficient Replication Complex Formation in Mosquito Cells.

Bartholomeeusen K, Utt A, Coppens S, Rausalu K, Vereecken K, Ariën KK, Merits A.

J Virol. 2018 Jun 29;92(14). pii: e00152-18. doi: 10.1128/JVI.00152-18. Print 2018 Jul 15.

8.

Partially Uncleaved Alphavirus Replicase Forms Spherule Structures in the Presence and Absence of RNA Template.

Hellström K, Kallio K, Utt A, Quirin T, Jokitalo E, Merits A, Ahola T.

J Virol. 2017 Aug 24;91(18). pii: e00787-17. doi: 10.1128/JVI.00787-17. Print 2017 Sep 15.

9.

Chikungunya virus infectivity, RNA replication and non-structural polyprotein processing depend on the nsP2 protease's active site cysteine residue.

Rausalu K, Utt A, Quirin T, Varghese FS, Žusinaite E, Das PK, Ahola T, Merits A.

Sci Rep. 2016 Nov 15;6:37124. doi: 10.1038/srep37124.

10.

Design and Validation of Novel Chikungunya Virus Protease Inhibitors.

Das PK, Puusepp L, Varghese FS, Utt A, Ahola T, Kananovich DG, Lopp M, Merits A, Karelson M.

Antimicrob Agents Chemother. 2016 Nov 21;60(12):7382-7395. Print 2016 Dec.

11.

Correction for Utt et al., Mutations Conferring a Noncytotoxic Phenotype on Chikungunya Virus Replicons Compromise Enzymatic Properties of Nonstructural Protein 2.

Utt A, Das PK, Varjak M, Lulla V, Lulla A, Merits A.

J Virol. 2016 Aug 12;90(17):8030. doi: 10.1128/JVI.01167-16. Print 2016 Sep 1. No abstract available.

12.

Correction for Thaa et al., Differential Phosphatidylinositol-3-Kinase-Akt-mTOR Activation by Semliki Forest and Chikungunya Viruses Is Dependent on nsP3 and Connected to Replication Complex Internalization.

Thaa B, Biasiotto R, Eng K, Neuvonen M, Götte B, Rheinemann L, Mutso M, Utt A, Varghese F, Balistreri G, Merits A, Ahola T, M McInerney G.

J Virol. 2016 Mar 28;90(8):4256. doi: 10.1128/JVI.00202-16. Print 2016 Apr. No abstract available.

13.

Versatile Trans-Replication Systems for Chikungunya Virus Allow Functional Analysis and Tagging of Every Replicase Protein.

Utt A, Quirin T, Saul S, Hellström K, Ahola T, Merits A.

PLoS One. 2016 Mar 10;11(3):e0151616. doi: 10.1371/journal.pone.0151616. eCollection 2016.

14.

Differential Phosphatidylinositol-3-Kinase-Akt-mTOR Activation by Semliki Forest and Chikungunya Viruses Is Dependent on nsP3 and Connected to Replication Complex Internalization.

Thaa B, Biasiotto R, Eng K, Neuvonen M, Götte B, Rheinemann L, Mutso M, Utt A, Varghese F, Balistreri G, Merits A, Ahola T, McInerney GM.

J Virol. 2015 Nov;89(22):11420-37. doi: 10.1128/JVI.01579-15. Epub 2015 Sep 2. Erratum in: J Virol. 2016 Apr 15;90(8):4256.

15.

Mutations conferring a noncytotoxic phenotype on chikungunya virus replicons compromise enzymatic properties of nonstructural protein 2.

Utt A, Das PK, Varjak M, Lulla V, Lulla A, Merits A.

J Virol. 2015 Mar;89(6):3145-62. doi: 10.1128/JVI.03213-14. Epub 2014 Dec 31. Erratum in: J Virol. 2016 Aug 12;90(17 ):8030.

16.

RIG-I and MDA-5 detection of viral RNA-dependent RNA polymerase activity restricts positive-strand RNA virus replication.

Nikonov A, Mölder T, Sikut R, Kiiver K, Männik A, Toots U, Lulla A, Lulla V, Utt A, Merits A, Ustav M.

PLoS Pathog. 2013;9(9):e1003610. doi: 10.1371/journal.ppat.1003610. Epub 2013 Sep 5.

17.

Inhibitors of alphavirus entry and replication identified with a stable Chikungunya replicon cell line and virus-based assays.

Pohjala L, Utt A, Varjak M, Lulla A, Merits A, Ahola T, Tammela P.

PLoS One. 2011;6(12):e28923. doi: 10.1371/journal.pone.0028923. Epub 2011 Dec 19.

18.

The effects of rearing method on social behaviors of mentored, captive-reared juvenile California condors.

Utt AC, Harvey NC, Hayes WK, Carter RL.

Zoo Biol. 2008 Jan;27(1):1-18. doi: 10.1002/zoo.20151.

PMID:
19360600

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