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Items: 13


Safety, Pharmacokinetics, and Food Effect of Tebipenem Pivoxil Hydrobromide after Single and Multiple Ascending Oral Doses in Healthy Adult Subjects.

Eckburg PB, Jain A, Walpole S, Moore G, Utley L, Manyak E, Dane A, Melnick D.

Antimicrob Agents Chemother. 2019 Aug 23;63(9). pii: e00618-19. doi: 10.1128/AAC.00618-19. Print 2019 Sep.


Safety, Tolerability, Pharmacokinetics, and Drug Interaction Potential of SPR741, an Intravenous Potentiator, after Single and Multiple Ascending Doses and When Combined with β-Lactam Antibiotics in Healthy Subjects.

Eckburg PB, Lister T, Walpole S, Keutzer T, Utley L, Tomayko J, Kopp E, Farinola N, Coleman S.

Antimicrob Agents Chemother. 2019 Aug 23;63(9). pii: e00892-19. doi: 10.1128/AAC.00892-19. Print 2019 Sep.


Tebipenem, the first oral carbapenem antibiotic.

Jain A, Utley L, Parr TR, Zabawa T, Pucci MJ.

Expert Rev Anti Infect Ther. 2018 Jul;16(7):513-522. doi: 10.1080/14787210.2018.1496821. Epub 2018 Jul 27. Review.


Assessment of the In Vivo Activity of SPR741 in Combination with Azithromycin against Multidrug-Resistant Enterobacteriaceae Isolates in the Neutropenic Murine Thigh Infection Model.

Stainton SM, Abdelraouf K, Utley L, Pucci MJ, Lister T, Nicolau DP.

Antimicrob Agents Chemother. 2018 Jun 26;62(7). pii: e00239-18. doi: 10.1128/AAC.00239-18. Print 2018 Jul.


Discovery of AG-120 (Ivosidenib): A First-in-Class Mutant IDH1 Inhibitor for the Treatment of IDH1 Mutant Cancers.

Popovici-Muller J, Lemieux RM, Artin E, Saunders JO, Salituro FG, Travins J, Cianchetta G, Cai Z, Zhou D, Cui D, Chen P, Straley K, Tobin E, Wang F, David MD, Penard-Lacronique V, Quivoron C, Saada V, de Botton S, Gross S, Dang L, Yang H, Utley L, Chen Y, Kim H, Jin S, Gu Z, Yao G, Luo Z, Lv X, Fang C, Yan L, Olaharski A, Silverman L, Biller S, Su SM, Yen K.

ACS Med Chem Lett. 2018 Jan 19;9(4):300-305. doi: 10.1021/acsmedchemlett.7b00421. eCollection 2018 Apr 12.


Rare Multidrug-Resistant Pulmonary Nocardiosis in AIDS.

Onaiwu CO, Velagapudi M, Sarsam L, Utley L, Bricker L, Bendi VS, Vivekanandan R.

Cureus. 2017 Nov 11;9(11):e1839. doi: 10.7759/cureus.1839.


A practical synthesis of xylo- and arabinofuranoside precursors by diastereoselective reduction using Corey-Bakshi-Shibata catalyst.

Utley LM, Maldonado J, Awad AM.

Nucleosides Nucleotides Nucleic Acids. 2018 Jan 2;37(1):20-34. doi: 10.1080/15257770.2017.1414240. Epub 2018 Jan 16.


Discovery of inhibitors of 4'-phosphopantetheine adenylyltransferase (PPAT) to validate PPAT as a target for antibacterial therapy.

de Jonge BL, Walkup GK, Lahiri SD, Huynh H, Neckermann G, Utley L, Nash TJ, Brock J, San Martin M, Kutschke A, Johnstone M, Laganas V, Hajec L, Gu RF, Ni H, Chen B, Hutchings K, Holt E, McKinney D, Gao N, Livchak S, Thresher J.

Antimicrob Agents Chemother. 2013 Dec;57(12):6005-15. doi: 10.1128/AAC.01661-13. Epub 2013 Sep 16.


Preclinical pharmacokinetic/pharmacodynamic models to predict synergistic effects of co-administered anti-cancer agents.

Goteti K, Garner CE, Utley L, Dai J, Ashwell S, Moustakas DT, Gönen M, Schwartz GK, Kern SE, Zabludoff S, Brassil PJ.

Cancer Chemother Pharmacol. 2010 Jul;66(2):245-54. doi: 10.1007/s00280-009-1153-z. Epub 2009 Oct 16.


Insect repellent [correction of repellant] interactions: sunscreens enhance DEET (N,N-diethyl-m-toluamide) absorption.

Ross EA, Savage KA, Utley LJ, Tebbett IR.

Drug Metab Dispos. 2004 Aug;32(8):783-5.


Transluminal extraction catheter atherectomy followed by immediate stenting in treatment of saphenous vein grafts.

Braden GA, Xenopoulos NP, Young T, Utley L, Kutcher MA, Applegate RJ.

J Am Coll Cardiol. 1997 Sep;30(3):657-63.


Cellular localization of CD4 in the human placenta. Implications for maternal-to-fetal transmission of HIV.

Lairmore MD, Cuthbert PS, Utley LL, Morgan CJ, Dezzutti CS, Anderson CL, Sedmak DD.

J Immunol. 1993 Aug 1;151(3):1673-81.


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