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Items: 37

1.

Identification of Cyanobacterial Strains with Potential for the Treatment of Obesity-Related Co-Morbidities by Bioactivity, Toxicity Evaluation and Metabolite Profiling.

Costa M, Rosa F, Ribeiro T, Hernandez-Bautista R, Bonaldo M, Gonçalves Silva N, Eiríksson F, Thorsteinsdóttir M, Ussar S, Urbatzka R.

Mar Drugs. 2019 May 10;17(5). pii: E280. doi: 10.3390/md17050280.

2.

Developmental and functional heterogeneity of white adipocytes within a single fat depot.

Lee KY, Luong Q, Sharma R, Dreyfuss JM, Ussar S, Kahn CR.

EMBO J. 2019 Feb 1;38(3). pii: e99291. doi: 10.15252/embj.201899291. Epub 2018 Dec 10.

PMID:
30530479
3.

Chronic d-serine supplementation impairs insulin secretion.

Suwandhi L, Hausmann S, Braun A, Gruber T, Heinzmann SS, Gálvez EJC, Buck A, Legutko B, Israel A, Feuchtinger A, Haythorne E, Staiger H, Heni M, Häring HU, Schmitt-Kopplin P, Walch A, Cáceres CG, Tschöp MH, Rutter GA, Strowig T, Elsner M, Ussar S.

Mol Metab. 2018 Oct;16:191-202. doi: 10.1016/j.molmet.2018.07.002. Epub 2018 Jul 25.

4.

Loss of periostin occurs in aging adipose tissue of mice and its genetic ablation impairs adipose tissue lipid metabolism.

Graja A, Garcia-Carrizo F, Jank AM, Gohlke S, Ambrosi TH, Jonas W, Ussar S, Kern M, Schürmann A, Aleksandrova K, Blüher M, Schulz TJ.

Aging Cell. 2018 Oct;17(5):e12810. doi: 10.1111/acel.12810. Epub 2018 Aug 7.

5.

Diet, Genetics, and the Gut Microbiome Drive Dynamic Changes in Plasma Metabolites.

Fujisaka S, Avila-Pacheco J, Soto M, Kostic A, Dreyfuss JM, Pan H, Ussar S, Altindis E, Li N, Bry L, Clish CB, Kahn CR.

Cell Rep. 2018 Mar 13;22(11):3072-3086. doi: 10.1016/j.celrep.2018.02.060.

6.

Heterogeneity of adipose tissue in development and metabolic function.

Schoettl T, Fischer IP, Ussar S.

J Exp Biol. 2018 Mar 7;221(Pt Suppl 1). pii: jeb162958. doi: 10.1242/jeb.162958. Review.

7.

A history of obesity leaves an inflammatory fingerprint in liver and adipose tissue.

Fischer IP, Irmler M, Meyer CW, Sachs SJ, Neff F, Hrabě de Angelis M, Beckers J, Tschöp MH, Hofmann SM, Ussar S.

Int J Obes (Lond). 2018 Mar;42(3):507-517. doi: 10.1038/ijo.2017.224. Epub 2017 Sep 13.

8.

Tbx15 Defines a Glycolytic Subpopulation and White Adipocyte Heterogeneity.

Lee KY, Sharma R, Gase G, Ussar S, Li Y, Welch L, Berryman DE, Kispert A, Bluher M, Kahn CR.

Diabetes. 2017 Nov;66(11):2822-2829. doi: 10.2337/db17-0218. Epub 2017 Aug 28.

9.

Extracellular calcium modulates brown adipocyte differentiation and identity.

Pramme-Steinwachs I, Jastroch M, Ussar S.

Sci Rep. 2017 Aug 21;7(1):8888. doi: 10.1038/s41598-017-09025-3.

10.
11.

Insulin resistance in vascular endothelial cells promotes intestinal tumour formation.

Wang X, Häring MF, Rathjen T, Lockhart SM, Sørensen D, Ussar S, Rasmussen LM, Bertagnolli MM, Kahn CR, Rask-Madsen C.

Oncogene. 2017 Aug 31;36(35):4987-4996. doi: 10.1038/onc.2017.107. Epub 2017 May 1.

12.

Regulation of Glucose Uptake and Enteroendocrine Function by the Intestinal Epithelial Insulin Receptor.

Ussar S, Haering MF, Fujisaka S, Lutter D, Lee KY, Li N, Gerber GK, Bry L, Kahn CR.

Diabetes. 2017 Apr;66(4):886-896. doi: 10.2337/db15-1349. Epub 2017 Jan 17.

13.

Antibiotic effects on gut microbiota and metabolism are host dependent.

Fujisaka S, Ussar S, Clish C, Devkota S, Dreyfuss JM, Sakaguchi M, Soto M, Konishi M, Softic S, Altindis E, Li N, Gerber G, Bry L, Kahn CR.

J Clin Invest. 2016 Dec 1;126(12):4430-4443. doi: 10.1172/JCI86674. Epub 2016 Oct 24.

14.

Interactions between host genetics and gut microbiome in diabetes and metabolic syndrome.

Ussar S, Fujisaka S, Kahn CR.

Mol Metab. 2016 Jul 18;5(9):795-803. doi: 10.1016/j.molmet.2016.07.004. eCollection 2016 Sep. Review.

15.

Insulin receptor trafficking steers insulin action.

Hausmann S, Ussar S.

Mol Metab. 2016 Feb 23;5(4):253-254. doi: 10.1016/j.molmet.2016.02.004. eCollection 2016 Apr. No abstract available.

16.

Interactions between Gut Microbiota, Host Genetics and Diet Modulate the Predisposition to Obesity and Metabolic Syndrome.

Ussar S, Griffin NW, Bezy O, Fujisaka S, Vienberg S, Softic S, Deng L, Bry L, Gordon JI, Kahn CR.

Cell Metab. 2015 Sep 1;22(3):516-530. doi: 10.1016/j.cmet.2015.07.007. Epub 2015 Aug 20. Erratum in: Cell Metab. 2016 Mar 8;23(3):564-6.

17.

Tbx15 controls skeletal muscle fibre-type determination and muscle metabolism.

Lee KY, Singh MK, Ussar S, Wetzel P, Hirshman MF, Goodyear LJ, Kispert A, Kahn CR.

Nat Commun. 2015 Aug 24;6:8054. doi: 10.1038/ncomms9054.

18.

[Br]eaking FAt.

Ussar S, Tschöp MH.

Cell. 2014 Oct 9;159(2):238-40. doi: 10.1016/j.cell.2014.09.045.

19.

ASC-1, PAT2, and P2RX5 are cell surface markers for white, beige, and brown adipocytes.

Ussar S, Lee KY, Dankel SN, Boucher J, Haering MF, Kleinridders A, Thomou T, Xue R, Macotela Y, Cypess AM, Tseng YH, Mellgren G, Kahn CR.

Sci Transl Med. 2014 Jul 30;6(247):247ra103. doi: 10.1126/scitranslmed.3008490.

20.

Linking maternal obesity to early insulin resistance.

Ussar S.

Mol Metab. 2014 Feb 7;3(3):219-20. doi: 10.1016/j.molmet.2014.01.013. eCollection 2014 Jun. No abstract available.

21.

Kindlin-1 controls Wnt and TGF-β availability to regulate cutaneous stem cell proliferation.

Rognoni E, Widmaier M, Jakobson M, Ruppert R, Ussar S, Katsougkri D, Böttcher RT, Lai-Cheong JE, Rifkin DB, McGrath JA, Fässler R.

Nat Med. 2014 Apr;20(4):350-9. doi: 10.1038/nm.3490. Epub 2014 Mar 30.

22.

Leptin regulation of Hsp60 impacts hypothalamic insulin signaling.

Kleinridders A, Lauritzen HP, Ussar S, Christensen JH, Mori MA, Bross P, Kahn CR.

J Clin Invest. 2013 Nov;123(11):4667-80.

23.

Sirt3 regulates metabolic flexibility of skeletal muscle through reversible enzymatic deacetylation.

Jing E, O'Neill BT, Rardin MJ, Kleinridders A, Ilkeyeva OR, Ussar S, Bain JR, Lee KY, Verdin EM, Newgard CB, Gibson BW, Kahn CR.

Diabetes. 2013 Oct;62(10):3404-17. doi: 10.2337/db12-1650. Epub 2013 Jul 8.

24.

Lessons on conditional gene targeting in mouse adipose tissue.

Lee KY, Russell SJ, Ussar S, Boucher J, Vernochet C, Mori MA, Smyth G, Rourk M, Cederquist C, Rosen ED, Kahn BB, Kahn CR.

Diabetes. 2013 Mar;62(3):864-74. doi: 10.2337/db12-1089. Epub 2013 Jan 15.

25.

Glypican-4 enhances insulin signaling via interaction with the insulin receptor and serves as a novel adipokine.

Ussar S, Bezy O, Blüher M, Kahn CR.

Diabetes. 2012 Sep;61(9):2289-98. doi: 10.2337/db11-1395. Epub 2012 Jun 29.

26.

Receptor antibodies as novel therapeutics for diabetes.

Ussar S, Vienberg SG, Kahn CR.

Sci Transl Med. 2011 Dec 14;3(113):113ps47. doi: 10.1126/scitranslmed.3003447.

27.

Loss-of-function FERMT1 mutations in kindler syndrome implicate a role for fermitin family homolog-1 in integrin activation.

Lai-Cheong JE, Parsons M, Tanaka A, Ussar S, South AP, Gomathy S, Mee JB, Barbaroux JB, Techanukul T, Almaani N, Clements SE, Hart IR, McGrath JA.

Am J Pathol. 2009 Oct;175(4):1431-41. doi: 10.2353/ajpath.2009.081154. Epub 2009 Sep 17.

28.

Leukocyte adhesion deficiency-III is caused by mutations in KINDLIN3 affecting integrin activation.

Svensson L, Howarth K, McDowall A, Patzak I, Evans R, Ussar S, Moser M, Metin A, Fried M, Tomlinson I, Hogg N.

Nat Med. 2009 Mar;15(3):306-12. doi: 10.1038/nm.1931. Epub 2009 Feb 22.

29.

Loss of Kindlin-1 causes skin atrophy and lethal neonatal intestinal epithelial dysfunction.

Ussar S, Moser M, Widmaier M, Rognoni E, Harrer C, Genzel-Boroviczeny O, Fässler R.

PLoS Genet. 2008 Dec;4(12):e1000289. doi: 10.1371/journal.pgen.1000289. Epub 2008 Dec 5.

30.

SILAC mouse for quantitative proteomics uncovers kindlin-3 as an essential factor for red blood cell function.

Krüger M, Moser M, Ussar S, Thievessen I, Luber CA, Forner F, Schmidt S, Zanivan S, Fässler R, Mann M.

Cell. 2008 Jul 25;134(2):353-64. doi: 10.1016/j.cell.2008.05.033.

31.

C-terminally truncated kindlin-1 leads to abnormal adhesion and migration of keratinocytes.

Has C, Ludwig RJ, Herz C, Kern JS, Ussar S, Ochsendorf FR, Kaufmann R, Schumann H, Kohlhase J, Bruckner-Tuderman L.

Br J Dermatol. 2008 Nov;159(5):1192-6. doi: 10.1111/j.1365-2133.2008.08760.x. Epub 2008 Jul 22.

PMID:
18652585
32.

Colocalization of kindlin-1, kindlin-2, and migfilin at keratinocyte focal adhesion and relevance to the pathophysiology of Kindler syndrome.

Lai-Cheong JE, Ussar S, Arita K, Hart IR, McGrath JA.

J Invest Dermatol. 2008 Sep;128(9):2156-65. doi: 10.1038/jid.2008.58. Epub 2008 Jun 5.

33.

Kindlin-2 controls bidirectional signaling of integrins.

Montanez E, Ussar S, Schifferer M, Bösl M, Zent R, Moser M, Fässler R.

Genes Dev. 2008 May 15;22(10):1325-30. doi: 10.1101/gad.469408.

34.

Kindlin-3 is essential for integrin activation and platelet aggregation.

Moser M, Nieswandt B, Ussar S, Pozgajova M, Fässler R.

Nat Med. 2008 Mar;14(3):325-30. doi: 10.1038/nm1722. Epub 2008 Feb 17.

PMID:
18278053
35.

The Kindlins: subcellular localization and expression during murine development.

Ussar S, Wang HV, Linder S, Fässler R, Moser M.

Exp Cell Res. 2006 Oct 1;312(16):3142-51. Epub 2006 Jun 29.

PMID:
16876785
36.

Integrin-linked kinase: integrin's mysterious partner.

Grashoff C, Thievessen I, Lorenz K, Ussar S, Fässler R.

Curr Opin Cell Biol. 2004 Oct;16(5):565-71. Review.

PMID:
15363808
37.

MEK1 and MEK2, different regulators of the G1/S transition.

Ussar S, Voss T.

J Biol Chem. 2004 Oct 15;279(42):43861-9. Epub 2004 Jul 28.

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