Phosphorylation of USP29 by CDK1 Governs TWIST1 Stability and Oncogenic Functions.
Guan T, Li M, Song Y, Chen J, Tang J, Zhang C, Wen Y, Yang X, Huang L, Zhu Y, Wang H, Ding K, Zheng J, Zhang H, Liu T.
Guan T, et al.
Adv Sci (Weinh). 2023 Apr;10(11):e2205873. doi: 10.1002/advs.202205873. Epub 2023 Feb 13.
Adv Sci (Weinh). 2023.
PMID: 36782089
Free PMC article.
However, the mechanism by which TWIST1 is deregulated in TNBC remains elusive. Here, USP29 is identified as a bona fide deubiquitinase of TWIST1. The deubiquitination of TWIST1 catalyzed by USP29 is required for its stabilization and subsequent EMT and CSC functions …
However, the mechanism by which TWIST1 is deregulated in TNBC remains elusive. Here, USP29 is identified as a bona fide deubiquitinas …