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Items: 17

1.

Identification of Human Sulfotransferases Involved in Lorcaserin N-Sulfamate Formation.

Sadeque AJ, Palamar S, Usmani KA, Chen C, Cerny MA, Chen WG.

Drug Metab Dispos. 2016 Apr;44(4):570-5. doi: 10.1124/dmd.115.067397. Epub 2016 Jan 12.

PMID:
26758853
2.

Discovery of a novel trans-1,4-dioxycyclohexane GPR119 agonist series.

Han S, Narayanan S, Kim SH, Calderon I, Zhu X, Kawasaki A, Yue D, Lehmann J, Wong A, Buzard DJ, Semple G, Carroll C, Chu ZL, Al-Sharmma H, Shu HH, Tung SF, Unett DJ, Behan DP, Yoon WH, Morgan M, Usmani KA, Chen C, Sadeque A, Leonard JN, Jones RM.

Bioorg Med Chem Lett. 2015 Aug 1;25(15):3034-8. doi: 10.1016/j.bmcl.2015.04.102. Epub 2015 May 23.

PMID:
26048791
3.

Discovery of 1a,2,5,5a-tetrahydro-1H-2,3-diaza-cyclopropa[a]pentalen-4-carboxamides as potent and selective CB2 receptor agonists.

Han S, Thoresen L, Zhu X, Narayanan S, Jung JK, Strah-Pleynet S, Decaire M, Choi K, Xiong Y, Yue D, Semple G, Thatte J, Solomon M, Fu L, Whelan K, Al-Shamma H, Gatlin J, Chen R, Dang H, Pride C, Gaidarov I, Unett DJ, Behan DP, Sadeque A, Usmani KA, Chen C, Edwards J, Morgan M, Jones RM.

Bioorg Med Chem Lett. 2015 Jan 15;25(2):322-6. doi: 10.1016/j.bmcl.2014.11.040. Epub 2014 Nov 26.

PMID:
25488844
4.

Identification of human cytochrome P450 and flavin-containing monooxygenase enzymes involved in the metabolism of lorcaserin, a novel selective human 5-hydroxytryptamine 2C agonist.

Usmani KA, Chen WG, Sadeque AJ.

Drug Metab Dispos. 2012 Apr;40(4):761-71. doi: 10.1124/dmd.111.043414. Epub 2012 Jan 20.

PMID:
22266842
5.

Identification of human UDP-glucuronosyltransferases involved in N-carbamoyl glucuronidation of lorcaserin.

Sadeque AJ, Usmani KA, Palamar S, Cerny MA, Chen WG.

Drug Metab Dispos. 2012 Apr;40(4):772-8. doi: 10.1124/dmd.111.043448. Epub 2012 Jan 18.

PMID:
22259019
6.

Inhibition of the human liver microsomal and human cytochrome P450 1A2 and 3A4 metabolism of estradiol by deployment-related and other chemicals.

Usmani KA, Cho TM, Rose RL, Hodgson E.

Drug Metab Dispos. 2006 Sep;34(9):1606-14. Epub 2006 Jun 21.

PMID:
16790556
7.
8.

Human cytochrome P450: metabolism of testosterone by CYP3A4 and inhibition by ketoconazole.

Usmani KA, Tang J.

Curr Protoc Toxicol. 2004 Jun;Chapter 4:Unit4.13. doi: 10.1002/0471140856.tx0413s20.

PMID:
20945304
10.

Genetic findings and functional studies of human CYP3A5 single nucleotide polymorphisms in different ethnic groups.

Lee SJ, Usmani KA, Chanas B, Ghanayem B, Xi T, Hodgson E, Mohrenweiser HW, Goldstein JA.

Pharmacogenetics. 2003 Aug;13(8):461-72.

PMID:
12893984
11.
12.

In vitro human metabolism and interactions of repellent N,N-diethyl-m-toluamide.

Usmani KA, Rose RL, Goldstein JA, Taylor WG, Brimfield AA, Hodgson E.

Drug Metab Dispos. 2002 Mar;30(3):289-94.

PMID:
11854147
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