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Items: 1 to 50 of 122

1.

Prostaglandin I2 suppresses the development of diet-induced nonalcoholic steatohepatitis in mice.

Kumei S, Yuhki KI, Kojima F, Kashiwagi H, Imamichi Y, Okumura T, Narumiya S, Ushikubi F.

FASEB J. 2018 May;32(5):2354-2365. doi: 10.1096/fj.201700590R. Epub 2017 Dec 15.

PMID:
29247122
2.

Diethylstilbestrol administration inhibits theca cell androgen and granulosa cell estrogen production in immature rat ovary.

Imamichi Y, Sekiguchi T, Kitano T, Kajitani T, Okada R, Inaoka Y, Miyamoto K, Uwada J, Takahashi S, Nemoto T, Mano A, Khan MRI, Islam MT, Yuhki KI, Kashiwagi H, Ushikubi F, Suzuki N, Taniguchi T, Yazawa T.

Sci Rep. 2017 Aug 21;7(1):8374. doi: 10.1038/s41598-017-08780-7.

3.

11-Ketotestosterone Is a Major Androgen Produced in Human Gonads.

Imamichi Y, Yuhki KI, Orisaka M, Kitano T, Mukai K, Ushikubi F, Taniguchi T, Umezawa A, Miyamoto K, Yazawa T.

J Clin Endocrinol Metab. 2016 Oct;101(10):3582-3591. Epub 2016 Jul 18.

PMID:
27428878
4.

Thromboxane A2 is Involved in Itch-associated Responses in Mice with Atopic Dermatitis-like Skin Lesions.

Andoh T, Yamamoto A, Haza S, Yuhki KI, Ushikubi F, Narumiya S, Kuraishi Y.

Acta Derm Venereol. 2016 Nov 2;96(7):899-904. doi: 10.2340/00015555-2437.

5.

The novel prostaglandin I2 mimetic ONO-1301 escapes desensitization in an antiplatelet effect due to its inhibitory action on thromboxane A2 synthesis in mice.

Kashiwagi H, Yuhki K, Kojima F, Kumei S, Takahata O, Sakai Y, Narumiya S, Ushikubi F.

J Pharmacol Exp Ther. 2015 May;353(2):269-78. doi: 10.1124/jpet.115.222612. Epub 2015 Mar 4.

6.

[PG/LT system and inflammation].

Kojima F, Yuhki K, Kashiwagi H, Kumei S, Ushikubi F.

Nihon Rinsho. 2012 Nov;70 Suppl 8:231-5. Japanese. No abstract available.

PMID:
23513842
7.

Prostacyclin stimulated integrin-dependent angiogenic effects of endothelial progenitor cells and mediated potent circulation recovery in ischemic hind limb model.

Aburakawa Y, Kawabe J, Okada M, Yamauchi A, Asanome A, Kabara M, Matsuki M, Takehara N, Nakagawa N, Okumura S, Minami Y, Mizukami Y, Yuhki K, Ushikubi F, Hasebe N.

Circ J. 2013;77(4):1053-62. Epub 2012 Dec 20.

8.

M1 is a major subtype of muscarinic acetylcholine receptors on mouse colonic epithelial cells.

Khan MR, Anisuzzaman AS, Semba S, Ma Y, Uwada J, Hayashi H, Suzuki Y, Takano T, Ikeuchi H, Uchino M, Maemoto A, Ushikubi F, Muramatsu I, Taniguchi T.

J Gastroenterol. 2013 Aug;48(8):885-96. doi: 10.1007/s00535-012-0718-5. Epub 2012 Dec 15.

PMID:
23242454
9.

17β-Estradiol is critical for the preovulatory induction of prostaglandin E(2) synthesis in mice.

Toda K, Ono M, Yuhki K, Ushikubi F, Saibara T.

Mol Cell Endocrinol. 2012 Oct 15;362(1-2):176-82. doi: 10.1016/j.mce.2012.06.006. Epub 2012 Jun 17.

PMID:
22713853
10.

The intrinsic prostaglandin E2-EP4 system of the renal tubular epithelium limits the development of tubulointerstitial fibrosis in mice.

Nakagawa N, Yuhki K, Kawabe J, Fujino T, Takahata O, Kabara M, Abe K, Kojima F, Kashiwagi H, Hasebe N, Kikuchi K, Sugimoto Y, Narumiya S, Ushikubi F.

Kidney Int. 2012 Jul;82(2):158-71. doi: 10.1038/ki.2012.115. Epub 2012 Apr 18.

11.

Potential roles of microsomal prostaglandin E synthase-1 in rheumatoid arthritis.

Kojima F, Matnani RG, Kawai S, Ushikubi F, Crofford LJ.

Inflamm Regen. 2011 Mar;31(2):157-166.

12.

[Endocannabinoid system].

Yuhki K, Kashiwagi H, Kojima F, Ushikubi F.

Nihon Rinsho. 2011 Jan;69 Suppl 1:331-5. Review. Japanese. No abstract available.

PMID:
21766619
13.

Thromboxane receptor activation enhances striatal dopamine release, leading to suppression of GABAergic transmission and enhanced sugar intake.

Mitsumori T, Furuyashiki T, Momiyama T, Nishi A, Shuto T, Hayakawa T, Ushikubi F, Kitaoka S, Aoki T, Inoue H, Matsuoka T, Narumiya S.

Eur J Neurosci. 2011 Aug;34(4):594-604. doi: 10.1111/j.1460-9568.2011.07774.x. Epub 2011 Jul 12.

PMID:
21749493
14.

[Prostaglandin I2 and its metabolites].

Yuhki K, Kojima F, Kashiwagi H, Ushikubi F.

Nihon Rinsho. 2010 Jul;68 Suppl 7:29-32. Japanese. No abstract available.

PMID:
20960743
15.

[Prostaglandin E1, E2 and their metabolites].

Kojima F, Yuhki K, Kashiwagi H, Ushikubi F.

Nihon Rinsho. 2010 Jul;68 Suppl 7:20-4. Japanese. No abstract available.

PMID:
20960741
16.

Roles of prostanoids in the pathogenesis of cardiovascular diseases: Novel insights from knockout mouse studies.

Yuhki K, Kojima F, Kashiwagi H, Kawabe J, Fujino T, Narumiya S, Ushikubi F.

Pharmacol Ther. 2011 Feb;129(2):195-205. doi: 10.1016/j.pharmthera.2010.09.004. Review.

PMID:
20920529
17.

Selective activation of the prostaglandin E2 receptor subtype EP2 or EP4 leads to inhibition of platelet aggregation.

Kuriyama S, Kashiwagi H, Yuhki K, Kojima F, Yamada T, Fujino T, Hara A, Takayama K, Maruyama T, Yoshida A, Narumiya S, Ushikubi F.

Thromb Haemost. 2010 Oct;104(4):796-803. doi: 10.1160/TH10-01-0043. Epub 2010 Jul 20.

PMID:
20664890
18.

Prostacyclin in vascular diseases. - Recent insights and future perspectives -.

Kawabe J, Ushikubi F, Hasebe N.

Circ J. 2010 May;74(5):836-43. Epub 2010 Apr 15. Review.

19.

Roles of prostanoids in the pathogenesis of cardiovascular diseases.

Yuhki K, Kashiwagi H, Kojima F, Kawabe J, Ushikubi F.

Int Angiol. 2010 Apr;29(2 Suppl):19-27. Review.

PMID:
20357745
20.

Prostaglandin I2 promotes recruitment of endothelial progenitor cells and limits vascular remodeling.

Kawabe J, Yuhki K, Okada M, Kanno T, Yamauchi A, Tashiro N, Sasaki T, Okumura S, Nakagawa N, Aburakawa Y, Takehara N, Fujino T, Hasebe N, Narumiya S, Ushikubi F.

Arterioscler Thromb Vasc Biol. 2010 Mar;30(3):464-70. doi: 10.1161/ATVBAHA.109.193730. Epub 2009 Dec 10.

PMID:
20007911
21.

[Roles of the prostanoids in the cardiovascular diseases].

Yuhki K, Ushikubi F.

Seikagaku. 2009 Feb;81(2):84-94. Review. Japanese. No abstract available.

PMID:
19306653
22.

Prostaglandin I2 plays a key role in zymosan-induced mouse pleurisy.

Yuhki K, Ushikubi F, Naraba H, Ueno A, Kato H, Kojima F, Narumiya S, Sugimoto Y, Matsushita M, Oh-Ishi S.

J Pharmacol Exp Ther. 2008 May;325(2):601-9. doi: 10.1124/jpet.107.134494. Epub 2008 Feb 6.

23.

Oral pretreatment with ebselen enhances heat shock protein 72 expression and reduces myocardial infarct size.

Baljinnyam E, Hasebe N, Morihira M, Sumitomo K, Matsusaka T, Fujino T, Fukuzawa J, Ushikubi F, Kikuchi K.

Hypertens Res. 2006 Nov;29(11):905-13.

PMID:
17345791
24.

[Roles of prostanoids in the kidney--studies using mice deficient in prostanoid receptors].

Fujino T, Hasebe N, Kikuchi K, Ushikubi F.

Nihon Rinsho. 2006 Feb;64 Suppl 2:203-8. Review. Japanese. No abstract available.

PMID:
16523888
25.

Prostaglandin E receptor EP1 controls impulsive behavior under stress.

Matsuoka Y, Furuyashiki T, Yamada K, Nagai T, Bito H, Tanaka Y, Kitaoka S, Ushikubi F, Nabeshima T, Narumiya S.

Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):16066-71. Epub 2005 Oct 24.

26.

Fat, keeping the heart healthy?

Yuhki K, Kawabe J, Ushikubi F.

Nat Med. 2005 Oct;11(10):1048-9. No abstract available.

PMID:
16211035
27.

Augmented cardiac hypertrophy in response to pressure overload in mice lacking the prostaglandin I2 receptor.

Hara A, Yuhki K, Fujino T, Yamada T, Takayama K, Kuriyama S, Takahata O, Karibe H, Okada Y, Xiao CY, Ma H, Narumiya S, Ushikubi F.

Circulation. 2005 Jul 5;112(1):84-92. Epub 2005 Jun 27.

PMID:
15983244
28.

Involvement of cyclooxygenase-2 and EP3 prostaglandin receptor in acute herpetic but not postherpetic pain in mice.

Takasaki I, Nojima H, Shiraki K, Sugimoto Y, Ichikawa A, Ushikubi F, Narumiya S, Kuraishi Y.

Neuropharmacology. 2005 Sep;49(3):283-92.

PMID:
15925391
29.

Thromboxane A2 and prostaglandin F2alpha mediate inflammatory tachycardia.

Takayama K, Yuhki K, Ono K, Fujino T, Hara A, Yamada T, Kuriyama S, Karibe H, Okada Y, Takahata O, Taniguchi T, Iijima T, Iwasaki H, Narumiya S, Ushikubi F.

Nat Med. 2005 May;11(5):562-6. Epub 2005 Apr 17.

PMID:
15834430
30.

Effects of salt loading on blood pressure in mice lacking the prostanoid receptor gene.

Watanabe H, Katoh T, Eiro M, Iwamoto M, Ushikubi F, Narumiya S, Watanabe T.

Circ J. 2005 Jan;69(1):124-6.

31.

Decreased susceptibility to renovascular hypertension in mice lacking the prostaglandin I2 receptor IP.

Fujino T, Nakagawa N, Yuhki K, Hara A, Yamada T, Takayama K, Kuriyama S, Hosoki Y, Takahata O, Taniguchi T, Fukuzawa J, Hasebe N, Kikuchi K, Narumiya S, Ushikubi F.

J Clin Invest. 2004 Sep;114(6):805-12.

32.

Prostaglandin receptors EP2, EP3, and IP mediate exudate formation in carrageenin-induced mouse pleurisy.

Yuhki K, Ueno A, Naraba H, Kojima F, Ushikubi F, Narumiya S, Oh-ishi S.

J Pharmacol Exp Ther. 2004 Dec;311(3):1218-24. Epub 2004 Aug 17.

33.

An EP4 receptor agonist prevents indomethacin-induced closure of rat ductus arteriosus in vivo.

Kajino H, Taniguchi T, Fujieda K, Ushikubi F, Muramatsu I.

Pediatr Res. 2004 Oct;56(4):586-90. Epub 2004 Aug 4.

PMID:
15295094
34.

Prostaglandin E2 protects the heart from ischemia-reperfusion injury via its receptor subtype EP4.

Xiao CY, Yuhki K, Hara A, Fujino T, Kuriyama S, Yamada T, Takayama K, Takahata O, Karibe H, Taniguchi T, Narumiya S, Ushikubi F.

Circulation. 2004 May 25;109(20):2462-8. Epub 2004 May 3.

PMID:
15123528
35.

[Pathophysiological roles of the prostanoids in the cardiovascular system: studies using mice deficient in prostanoid receptors].

Hara A, Yuhki K, Fujino T, Narumiya S, Ushikubi F.

Nihon Yakurigaku Zasshi. 2003 Nov;122(5):384-90. Review. Japanese.

PMID:
14569157
36.

Thromboxane A2 regulates vascular tone via its inhibitory effect on the expression of inducible nitric oxide synthase.

Yamada T, Fujino T, Yuhki K, Hara A, Karibe H, Takahata O, Okada Y, Xiao CY, Takayama K, Kuriyama S, Taniguchi T, Shiokoshi T, Ohsaki Y, Kikuchi K, Narumiya S, Ushikubi F.

Circulation. 2003 Nov 11;108(19):2381-6. Epub 2003 Oct 13.

PMID:
14557367
37.

Characteristics of thermoregulatory and febrile responses in mice deficient in prostaglandin EP1 and EP3 receptors.

Oka T, Oka K, Kobayashi T, Sugimoto Y, Ichikawa A, Ushikubi F, Narumiya S, Saper CB.

J Physiol. 2003 Sep 15;551(Pt 3):945-54. Epub 2003 Jul 1.

38.

Functional evidence for interaction between prostaglandin EP3 and kappa-opioid receptor pathways in tactile pain induced by human immunodeficiency virus type-1 (HIV-1) glycoprotein gp120.

Minami T, Matsumura S, Mabuchi T, Kobayashi T, Sugimoto Y, Ushikubi F, Ichikawa A, Narumiya S, Ito S.

Neuropharmacology. 2003 Jul;45(1):96-105.

PMID:
12814662
39.

Thromboxane A2 modulates interaction of dendritic cells and T cells and regulates acquired immunity.

Kabashima K, Murata T, Tanaka H, Matsuoka T, Sakata D, Yoshida N, Katagiri K, Kinashi T, Tanaka T, Miyasaka M, Nagai H, Ushikubi F, Narumiya S.

Nat Immunol. 2003 Jul;4(7):694-701. Epub 2003 Jun 1.

PMID:
12778172
40.

Impaired adrenocorticotropic hormone response to bacterial endotoxin in mice deficient in prostaglandin E receptor EP1 and EP3 subtypes.

Matsuoka Y, Furuyashiki T, Bito H, Ushikubi F, Tanaka Y, Kobayashi T, Muro S, Satoh N, Kayahara T, Higashi M, Mizoguchi A, Shichi H, Fukuda Y, Nakao K, Narumiya S.

Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):4132-7. Epub 2003 Mar 17.

41.

Effects of the prostanoids on the proliferation or hypertrophy of cultured murine aortic smooth muscle cells.

Fujino T, Yuhki K, Yamada T, Hara A, Takahata O, Okada Y, Xiao CY, Ma H, Karibe H, Iwashima Y, Fukuzawa J, Hasebe N, Kikuchi K, Narumiya S, Ushikubi F.

Br J Pharmacol. 2002 Jun;136(4):530-9.

42.

[The roles of the prostanoids played in the body].

Ushikubi F, Narumiya S.

Nihon Yakurigaku Zasshi. 2002 Apr;119(4):201-7. Review. Japanese.

PMID:
11979724
43.

Stimulation of bone formation and prevention of bone loss by prostaglandin E EP4 receptor activation.

Yoshida K, Oida H, Kobayashi T, Maruyama T, Tanaka M, Katayama T, Yamaguchi K, Segi E, Tsuboyama T, Matsushita M, Ito K, Ito Y, Sugimoto Y, Ushikubi F, Ohuchida S, Kondo K, Nakamura T, Narumiya S.

Proc Natl Acad Sci U S A. 2002 Apr 2;99(7):4580-5. Epub 2002 Mar 26.

44.

Roles of prostaglandin I(2) and thromboxane A(2) in cardiac ischemia-reperfusion injury: a study using mice lacking their respective receptors.

Xiao CY, Hara A, Yuhki K, Fujino T, Ma H, Okada Y, Takahata O, Yamada T, Murata T, Narumiya S, Ushikubi F.

Circulation. 2001 Oct 30;104(18):2210-5.

PMID:
11684633
45.

Increased bleeding tendency and decreased susceptibility to thromboembolism in mice lacking the prostaglandin E receptor subtype EP(3).

Ma H, Hara A, Xiao CY, Okada Y, Takahata O, Nakaya K, Sugimoto Y, Ichikawa A, Narumiya S, Ushikubi F.

Circulation. 2001 Sep 4;104(10):1176-80.

PMID:
11535576
46.

Acceleration of intestinal polyposis through prostaglandin receptor EP2 in Apc(Delta 716) knockout mice.

Sonoshita M, Takaku K, Sasaki N, Sugimoto Y, Ushikubi F, Narumiya S, Oshima M, Taketo MM.

Nat Med. 2001 Sep;7(9):1048-51.

PMID:
11533709
47.

Major roles of prostanoid receptors IP and EP(3) in endotoxin-induced enhancement of pain perception.

Ueno A, Matsumoto H, Naraba H, Ikeda Y, Ushikubi F, Matsuoka T, Narumiya S, Sugimoto Y, Ichikawa A, Oh-ishi S.

Biochem Pharmacol. 2001 Jul 15;62(2):157-60.

PMID:
11389873
48.

Characterization of EP receptor subtypes responsible for prostaglandin E2-induced pain responses by use of EP1 and EP3 receptor knockout mice.

Minami T, Nakano H, Kobayashi T, Sugimoto Y, Ushikubi F, Ichikawa A, Narumiya S, Ito S.

Br J Pharmacol. 2001 Jun;133(3):438-44.

49.

[Pain, fever and prostanoids].

Kuraishi Y, Ushikubi F.

Nihon Yakurigaku Zasshi. 2001 Apr;117(4):248-54. Review. Japanese.

PMID:
11338373
50.

Regulation of TNFalpha and interleukin-10 production by prostaglandins I(2) and E(2): studies with prostaglandin receptor-deficient mice and prostaglandin E-receptor subtype-selective synthetic agonists.

Shinomiya S, Naraba H, Ueno A, Utsunomiya I, Maruyama T, Ohuchida S, Ushikubi F, Yuki K, Narumiya S, Sugimoto Y, Ichikawa A, Oh-ishi S.

Biochem Pharmacol. 2001 May 1;61(9):1153-60.

PMID:
11301049

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