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Items: 1 to 50 of 482

1.

DNA methylation marker to estimate the breast cancer cell fraction in DNA samples.

Ishihara H, Yamashita S, Fujii S, Tanabe K, Mukai H, Ushijima T.

Med Oncol. 2018 Sep 14;35(11):147. doi: 10.1007/s12032-018-1207-3.

PMID:
30218172
2.

Pancreatic Cancer Cell Fraction Estimation in a DNA Sample.

Ishihara H, Yamashita S, Amano R, Kimura K, Hirakawa K, Ueda T, Murakami Y, Tamori A, Tanabe K, Kawada N, Hagihara A, Ushijima T.

Oncology. 2018 Aug 27:1-10. doi: 10.1159/000491637. [Epub ahead of print]

PMID:
30149376
3.
4.

Development of an integrated CRISPRi targeting ΔNp63 for treatment of squamous cell carcinoma.

Yoshida M, Yokota E, Sakuma T, Yamatsuji T, Takigawa N, Ushijima T, Yamamoto T, Fukazawa T, Naomoto Y.

Oncotarget. 2018 Jun 26;9(49):29220-29232. doi: 10.18632/oncotarget.25678. eCollection 2018 Jun 26.

5.

Methylation changes and aberrant expression of FGFR3 in Lewy body disease neurons.

Tsuchida T, Mano T, Koshi-Mano K, Bannai T, Matsubara T, Yamashita S, Ushijima T, Nagata K, Murayama S, Toda T, Tsuji S, Iwata A.

Brain Res. 2018 Oct 15;1697:59-66. doi: 10.1016/j.brainres.2018.06.017. Epub 2018 Jun 15.

PMID:
29909202
6.

Interaction between cardiac myosin-binding protein C and formin Fhod3.

Matsuyama S, Kage Y, Fujimoto N, Ushijima T, Tsuruda T, Kitamura K, Shiose A, Asada Y, Sumimoto H, Takeya R.

Proc Natl Acad Sci U S A. 2018 May 8;115(19):E4386-E4395. doi: 10.1073/pnas.1716498115. Epub 2018 Apr 23.

PMID:
29686099
7.

Acute torrential mitral regurgitation during transcatheter aortic valve replacement: a case report.

Yamashita Y, Sonoda H, Ushijima T, Shiose A.

Surg Case Rep. 2018 Apr 18;4(1):35. doi: 10.1186/s40792-018-0446-z.

8.

Low dose cadmium upregulates the expression of von Willebrand factor in endothelial cells.

Wang X, Dong F, Wang F, Yan S, Chen X, Tozawa H, Ushijima T, Kapron CM, Wada Y, Liu J.

Toxicol Lett. 2018 Jun 15;290:46-54. doi: 10.1016/j.toxlet.2018.03.020. Epub 2018 Mar 20.

PMID:
29571895
9.

Predictive value of genetic analysis for pathological complete response to preoperative treatment in HER2 positive, HR negative early breast cancer (PASSION trial).

Yamaguchi T, Mukai H, Takahashi M, Hara F, Yamauchi C, Yamashita S, Ushijima T.

Jpn J Clin Oncol. 2018 Apr 1;48(4):388-391. doi: 10.1093/jjco/hyy024.

PMID:
29506214
10.

A case of gastric wall implantation caused by EUS-FNA 22 months after pancreatic cancer resection.

Yasumoto M, Okabe Y, Ishikawa H, Kisaki J, Akiba J, Naito Y, Ishida Y, Ushijima T, Tsuruta O, Torimura T.

Endosc Ultrasound. 2018 Jan-Feb;7(1):64-66. doi: 10.4103/eus.eus_58_17. No abstract available.

11.

Novel epigenetic markers for gastric cancer risk stratification in individuals after Helicobacter pylori eradication.

Maeda M, Yamashita S, Shimazu T, Iida N, Takeshima H, Nakajima T, Oda I, Nanjo S, Kusano C, Mori A, Moro H, Yamada H, Tsugane S, Sugiyama T, Sakai Y, Ushijima T.

Gastric Cancer. 2018 Sep;21(5):745-755. doi: 10.1007/s10120-018-0803-4. Epub 2018 Feb 9.

PMID:
29427040
12.

Double non-contiguous fractures in a patient with spondylo-epiphyseal dysplasia with spinal ankylosis treated with open and percutaneous spinal fixation technique: a case report.

Ushijima T, Kawaguchi K, Matsumoto T, Takagi M, Kondoh T, Nishimura G, Iida A, Ikegawa S, Haga N, Kato G.

BMC Res Notes. 2018 Feb 7;11(1):106. doi: 10.1186/s13104-018-3227-7.

13.

[Epigenetic Alterations in Gastrointestinal Cancers: Diagnostic and Therapeutic Applications].

Ushijima T, Maeda M, Kawachi A.

Gan To Kagaku Ryoho. 2018 Jan;45(1):1-7. Review. Japanese.

PMID:
29362296
14.

Genetic and epigenetic alterations in normal tissues have differential impacts on cancer risk among tissues.

Yamashita S, Kishino T, Takahashi T, Shimazu T, Charvat H, Kakugawa Y, Nakajima T, Lee YC, Iida N, Maeda M, Hattori N, Takeshima H, Nagano R, Oda I, Tsugane S, Wu MS, Ushijima T.

Proc Natl Acad Sci U S A. 2018 Feb 6;115(6):1328-1333. doi: 10.1073/pnas.1717340115. Epub 2018 Jan 22.

15.

MACON: a web tool for computing DNA methylation data obtained by the Illumina Infinium Human DNA methylation BeadArray.

Iida N, Okuda Y, Ogasawara O, Yamashita S, Takeshima H, Ushijima T.

Epigenomics. 2018 Mar;10(3):249-258. doi: 10.2217/epi-2017-0093. Epub 2018 Jan 18.

PMID:
29343101
16.

Analysis of DNA Methylation in Tissues Exposed to Inflammation.

Hattori N, Ushijima T.

Methods Mol Biol. 2018;1725:185-199. doi: 10.1007/978-1-4939-7568-6_16.

PMID:
29322419
17.

A case of pancreatic neuroendocrine tumor with multiple cystic components of various sizes.

Yasumoto M, Okabe Y, Sugiyama G, Naito Y, Nakayama M, Hisaka T, Ishikawa H, Horiuchi H, Kunou Y, Ushijima T, Ishida Y, Tsuruta O, Torimura T.

Clin J Gastroenterol. 2018 Feb;11(1):87-91. doi: 10.1007/s12328-017-0798-0. Epub 2017 Dec 21.

PMID:
29270782
18.

Erythema multiforme induced by regorafenib.

Matsunaga M, Ushijima T, Fukahori M, Tanikawa K, Miwa K.

J Gen Fam Med. 2017 Mar 24;18(2):90-91. doi: 10.1002/jgf2.29. eCollection 2017 Apr. No abstract available.

19.

The actin-organizing formin protein Fhod3 is required for postnatal development and functional maintenance of the adult heart in mice.

Ushijima T, Fujimoto N, Matsuyama S, Kan-O M, Kiyonari H, Shioi G, Kage Y, Yamasaki S, Takeya R, Sumimoto H.

J Biol Chem. 2018 Jan 5;293(1):148-162. doi: 10.1074/jbc.M117.813931. Epub 2017 Nov 20.

PMID:
29158260
20.

A tissue microRNA signature that predicts the prognosis of breast cancer in young women.

Hironaka-Mitsuhashi A, Matsuzaki J, Takahashi RU, Yoshida M, Nezu Y, Yamamoto Y, Shiino S, Kinoshita T, Ushijima T, Hiraoka N, Shimizu C, Tamura K, Ochiya T.

PLoS One. 2017 Nov 15;12(11):e0187638. doi: 10.1371/journal.pone.0187638. eCollection 2017.

21.

Light Controls Protein Localization through Phytochrome-Mediated Alternative Promoter Selection.

Ushijima T, Hanada K, Gotoh E, Yamori W, Kodama Y, Tanaka H, Kusano M, Fukushima A, Tokizawa M, Yamamoto YY, Tada Y, Suzuki Y, Matsushita T.

Cell. 2017 Nov 30;171(6):1316-1325.e12. doi: 10.1016/j.cell.2017.10.018. Epub 2017 Nov 9.

PMID:
29129375
22.

Neuron-specific methylome analysis reveals epigenetic regulation and tau-related dysfunction of BRCA1 in Alzheimer's disease.

Mano T, Nagata K, Nonaka T, Tarutani A, Imamura T, Hashimoto T, Bannai T, Koshi-Mano K, Tsuchida T, Ohtomo R, Takahashi-Fujigasaki J, Yamashita S, Ohyagi Y, Yamasaki R, Tsuji S, Tamaoka A, Ikeuchi T, Saido TC, Iwatsubo T, Ushijima T, Murayama S, Hasegawa M, Iwata A.

Proc Natl Acad Sci U S A. 2017 Nov 7;114(45):E9645-E9654. doi: 10.1073/pnas.1707151114. Epub 2017 Oct 17.

23.

Roadmap for investigating epigenome deregulation and environmental origins of cancer.

Herceg Z, Ghantous A, Wild CP, Sklias A, Casati L, Duthie SJ, Fry R, Issa JP, Kellermayer R, Koturbash I, Kondo Y, Lepeule J, Lima SCS, Marsit CJ, Rakyan V, Saffery R, Taylor JA, Teschendorff AE, Ushijima T, Vineis P, Walker CL, Waterland RA, Wiemels J, Ambatipudi S, Degli Esposti D, Hernandez-Vargas H.

Int J Cancer. 2018 Mar 1;142(5):874-882. doi: 10.1002/ijc.31014. Epub 2017 Sep 13. Review.

24.

PRC2-Mediated Transcriptomic Alterations at the Embryonic Stage Govern Tumorigenesis and Clinical Outcome in MYCN-Driven Neuroblastoma.

Tsubota S, Kishida S, Shimamura T, Ohira M, Yamashita S, Cao D, Kiyonari S, Ushijima T, Kadomatsu K.

Cancer Res. 2017 Oct 1;77(19):5259-5271. doi: 10.1158/0008-5472.CAN-16-3144. Epub 2017 Aug 14.

PMID:
28807939
25.

A novel method to quantify base substitution mutations at the 10-6 per bp level in DNA samples.

Yamashita S, Iida N, Takeshima H, Hattori N, Maeda M, Kishino T, Nagano R, Shimazu T, Tsugane S, Ushijima T.

Cancer Lett. 2017 Sep 10;403:152-158. doi: 10.1016/j.canlet.2017.06.010. Epub 2017 Jun 19.

PMID:
28642169
26.

WNT Pathway Gene Mutations Are Associated With the Presence of Dysplasia in Colorectal Sessile Serrated Adenoma/Polyps.

Hashimoto T, Yamashita S, Yoshida H, Taniguchi H, Ushijima T, Yamada T, Saito Y, Ochiai A, Sekine S, Hiraoka N.

Am J Surg Pathol. 2017 Sep;41(9):1188-1197. doi: 10.1097/PAS.0000000000000877.

PMID:
28614199
27.

Targeting of super-enhancers and mutant BRAF can suppress growth of BRAF-mutant colon cancer cells via repression of MAPK signaling pathway.

Nakamura Y, Hattori N, Iida N, Yamashita S, Mori A, Kimura K, Yoshino T, Ushijima T.

Cancer Lett. 2017 Aug 28;402:100-109. doi: 10.1016/j.canlet.2017.05.017. Epub 2017 May 31.

PMID:
28576751
28.

A rare case of sarcoidosis in accessory spleen.

Okabe Y, Ushijima T, Yasunaga M, Mihara Y, Torimura T.

Gastrointest Endosc. 2017 Nov;86(5):918-919. doi: 10.1016/j.gie.2017.05.025. Epub 2017 May 27. No abstract available.

PMID:
28558961
29.

Meeting Report of the Fifth International Cancer Epigenetics Conference in Beijing, China, October 2016.

Gao D, Herman JG, Cui H, Jen J, Fuks F, Brock MV, Ushijima T, Croce C, Akiyama Y, Guo M.

Epigenomics. 2017 Jul;9(7):937-941. doi: 10.2217/epi-2017-0030. Epub 2017 May 22.

30.

How to stomach an epigenetic insult: the gastric cancer epigenome.

Padmanabhan N, Ushijima T, Tan P.

Nat Rev Gastroenterol Hepatol. 2017 Aug;14(8):467-478. doi: 10.1038/nrgastro.2017.53. Epub 2017 May 17. Review.

PMID:
28513632
31.

Identification of a TLR2-regulated gene signature associated with tumor cell growth in gastric cancer.

West AC, Tang K, Tye H, Yu L, Deng N, Najdovska M, Lin SJ, Balic JJ, Okochi-Takada E, McGuirk P, Keogh B, McCormack W, Bhathal PS, Reilly M, Oshima M, Ushijima T, Tan P, Jenkins BJ.

Oncogene. 2017 Sep 7;36(36):5134-5144. doi: 10.1038/onc.2017.121. Epub 2017 May 8.

PMID:
28481875
32.

Chronic treatment of non-small-cell lung cancer cells with gefitinib leads to an epigenetic loss of epithelial properties associated with reductions in microRNA-155 and -200c.

Narita M, Shimura E, Nagasawa A, Aiuchi T, Suda Y, Hamada Y, Ikegami D, Iwasawa C, Arakawa K, Igarashi K, Kuzumaki N, Yoshioka Y, Ochiya T, Takeshima H, Ushijima T, Narita M.

PLoS One. 2017 Feb 22;12(2):e0172115. doi: 10.1371/journal.pone.0172115. eCollection 2017.

33.

Autophagy impairment by Helicobacter pylori-induced methylation silencing of MAP1LC3Av1 promotes gastric carcinogenesis.

Muhammad JS, Nanjo S, Ando T, Yamashita S, Maekita T, Ushijima T, Tabuchi Y, Sugiyama T.

Int J Cancer. 2017 May 15;140(10):2272-2283. doi: 10.1002/ijc.30657. Epub 2017 Mar 14.

34.

Pathological complete response of HER2-positive breast cancer to trastuzumab and chemotherapy can be predicted by HSD17B4 methylation.

Fujii S, Yamashita S, Yamaguchi T, Takahashi M, Hozumi Y, Ushijima T, Mukai H.

Oncotarget. 2017 Mar 21;8(12):19039-19048. doi: 10.18632/oncotarget.15118.

35.

The Moment that KRAS Mutation Started to Evolve into Precision Medicine in Metastatic Colorectal Cancer.

Ushijima T, Yoshino T.

Cancer Res. 2016 Nov 15;76(22):6443-6444. doi: 10.1158/0008-5472.CAN-16-2867. No abstract available.

36.

Genome-wide methylation profiles in primary intracranial germ cell tumors indicate a primordial germ cell origin for germinomas.

Fukushima S, Yamashita S, Kobayashi H, Takami H, Fukuoka K, Nakamura T, Yamasaki K, Matsushita Y, Nakamura H, Totoki Y, Kato M, Suzuki T, Mishima K, Yanagisawa T, Mukasa A, Saito N, Kanamori M, Kumabe T, Tominaga T, Nagane M, Iuchi T, Yoshimoto K, Mizoguchi M, Tamura K, Sakai K, Sugiyama K, Nakada M, Yokogami K, Takeshima H, Kanemura Y, Matsuda M, Matsumura A, Kurozumi K, Ueki K, Nonaka M, Asai A, Kawahara N, Hirose Y, Takayama T, Nakazato Y, Narita Y, Shibata T, Matsutani M, Ushijima T, Nishikawa R, Ichimura K; Intracranial Germ Cell Tumor Genome Analysis Consortium (The iGCTConsortium).

Acta Neuropathol. 2017 Mar;133(3):445-462. doi: 10.1007/s00401-017-1673-2. Epub 2017 Jan 11.

PMID:
28078450
37.

Genome-wide DNA methylation profiling identifies primary central nervous system lymphoma as a distinct entity different from systemic diffuse large B-cell lymphoma.

Nakamura T, Yamashita S, Fukumura K, Nakabayashi J, Tanaka K, Tamura K, Tateishi K, Kinoshita M, Fukushima S, Takami H, Fukuoka K, Yamazaki K, Matsushita Y, Ohno M, Miyakita Y, Shibui S, Kubo A, Shuto T, Kocialkowski S, Yamanaka S, Mukasa A, Sasayama T, Mishima K, Maehara T, Kawahara N, Nagane M, Narita Y, Mano H, Ushijima T, Ichimura K.

Acta Neuropathol. 2017 Feb;133(2):321-324. doi: 10.1007/s00401-016-1664-8. Epub 2017 Jan 5. No abstract available.

PMID:
28058506
38.

High impact of methylation accumulation on metachronous gastric cancer: 5-year follow-up of a multicentre prospective cohort study.

Maeda M, Nakajima T, Oda I, Shimazu T, Yamamichi N, Maekita T, Asada K, Yokoi C, Ando T, Yoshida T, Nanjo S, Fujishiro M, Gotoda T, Ichinose M, Ushijima T.

Gut. 2017 Sep;66(9):1721-1723. doi: 10.1136/gutjnl-2016-313387. Epub 2016 Dec 21. No abstract available.

39.

Degree of methylation burden is determined by the exposure period to carcinogenic factors.

Takeshima H, Niwa T, Toyoda T, Wakabayashi M, Yamashita S, Ushijima T.

Cancer Sci. 2017 Mar;108(3):316-321. doi: 10.1111/cas.13136.

40.

Establishment of a high-throughput detection system for DNA demethylating agents.

Okochi-Takada E, Hattori N, Ito A, Niwa T, Wakabayashi M, Kimura K, Yoshida M, Ushijima T.

Epigenetics. 2018;13(2):147-155. doi: 10.1080/15592294.2016.1267887. Epub 2018 Mar 5.

PMID:
27935410
41.

Molecular mechanisms of gastric carcinogenesis.

Ushijima T, Hattori N, Yamashita S.

Nihon Shokakibyo Gakkai Zasshi. 2016;113(11):1868-1877. Japanese. No abstract available.

PMID:
27829598
42.

Mechanisms for the induction of gastric cancer by Helicobacter pylori infection: aberrant DNA methylation pathway.

Maeda M, Moro H, Ushijima T.

Gastric Cancer. 2017 Mar;20(Suppl 1):8-15. doi: 10.1007/s10120-016-0650-0. Epub 2016 Oct 7. Review.

PMID:
27718135
43.

A case of intragastric wall abscess developing after EUS-FNA in a patient with pancreatic body cancer.

Ushijima T, Okabe Y, Ishida Y, Fukahori M, Torimura T.

Gastrointest Endosc. 2017 May;85(5):1097-1098. doi: 10.1016/j.gie.2016.06.046. Epub 2016 Jun 25. No abstract available.

PMID:
27354103
44.

High-risk oral leukoplakia is associated with aberrant promoter methylation of multiple genes.

Abe M, Yamashita S, Mori Y, Abe T, Saijo H, Hoshi K, Ushijima T, Takato T.

BMC Cancer. 2016 Jun 3;16:350. doi: 10.1186/s12885-016-2371-5.

45.

mFOLFOX6 Chemotherapy after Resection of Anal Canal Mucinous Adenocarcinoma.

Matsunaga M, Miwa K, Oka Y, Nagasu S, Sakaue T, Fukahori M, Ushijima T, Akagi Y.

Case Rep Oncol. 2016 Apr 29;9(1):280-4. doi: 10.1159/000446066. eCollection 2016 Jan-Apr.

46.

Successful Treatment of Metastatic Anal Canal Adenocarcinoma with mFOLFOX6 + Bevacizumab.

Matsunaga M, Miwa K, Oka Y, Nagasu S, Sakaue T, Fukahori M, Ushijima T, Akagi Y.

Case Rep Oncol. 2016 Apr 26;9(1):249-54. doi: 10.1159/000446107. eCollection 2016 Jan-Apr.

47.

Quantification of pelvic tilt and rotation by width/height ratio of obturator foramina on anteroposterior radiographs.

Kanazawa M, Nakashima Y, Arai T, Ushijima T, Hirata M, Hara D, Iwamoto Y.

Hip Int. 2016 Sep 29;26(5):462-467. doi: 10.5301/hipint.5000374. Epub 2016 May 11.

PMID:
27174062
48.

Recurrent neomorphic mutations of MTOR in central nervous system and testicular germ cell tumors may be targeted for therapy.

Ichimura K, Fukushima S, Totoki Y, Matsushita Y, Otsuka A, Tomiyama A, Niwa T, Takami H, Nakamura T, Suzuki T, Fukuoka K, Yanagisawa T, Mishima K, Nakazato Y, Hosoda F, Narita Y, Shibui S, Yoshida A, Mukasa A, Saito N, Kumabe T, Kanamori M, Tominaga T, Kobayashi K, Shimizu S, Nagane M, Iuchi T, Mizoguchi M, Yoshimoto K, Tamura K, Maehara T, Sugiyama K, Nakada M, Sakai K, Kanemura Y, Nonaka M, Asai A, Yokogami K, Takeshima H, Kawahara N, Takayama T, Yao M, Kato M, Nakamura H, Hama N, Sakai R, Ushijima T, Matsutani M, Shibata T, Nishikawa R; Intracranial Germ Cell Tumor Genome Analysis Consortium.

Acta Neuropathol. 2016 Jun;131(6):889-901. doi: 10.1007/s00401-016-1557-x. Epub 2016 Mar 8.

PMID:
26956871
49.

Value of KRAS, BRAF, and PIK3CA Mutations and Survival Benefit from Systemic Chemotherapy in Colorectal Peritoneal Carcinomatosis.

Sasaki Y, Hamaguchi T, Yamada Y, Takahashi N, Shoji H, Honma Y, Iwasa S, Okita N, Takashima A, Kato K, Nagai Y, Taniguchi H, Boku N, Ushijima T, Shimada Y.

Asian Pac J Cancer Prev. 2016;17(2):539-43.

50.

Frequent PTPRK-RSPO3 fusions and RNF43 mutations in colorectal traditional serrated adenoma.

Sekine S, Yamashita S, Tanabe T, Hashimoto T, Yoshida H, Taniguchi H, Kojima M, Shinmura K, Saito Y, Hiraoka N, Ushijima T, Ochiai A.

J Pathol. 2016 Jun;239(2):133-8. doi: 10.1002/path.4709. Epub 2016 Apr 9.

PMID:
26924569

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