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Items: 14


Microbial genomic analysis reveals the essential role of inflammation in bacteria-induced colorectal cancer.

Arthur JC, Gharaibeh RZ, Mühlbauer M, Perez-Chanona E, Uronis JM, McCafferty J, Fodor AA, Jobin C.

Nat Commun. 2014 Sep 3;5:4724. doi: 10.1038/ncomms5724.


VSL#3 probiotic modifies mucosal microbial composition but does not reduce colitis-associated colorectal cancer.

Arthur JC, Gharaibeh RZ, Uronis JM, Perez-Chanona E, Sha W, Tomkovich S, Mühlbauer M, Fodor AA, Jobin C.

Sci Rep. 2013 Oct 8;3:2868. doi: 10.1038/srep02868.


Intestinal inflammation targets cancer-inducing activity of the microbiota.

Arthur JC, Perez-Chanona E, Mühlbauer M, Tomkovich S, Uronis JM, Fan TJ, Campbell BJ, Abujamel T, Dogan B, Rogers AB, Rhodes JM, Stintzi A, Simpson KW, Hansen JJ, Keku TO, Fodor AA, Jobin C.

Science. 2012 Oct 5;338(6103):120-3. doi: 10.1126/science.1224820. Epub 2012 Aug 16.


Histological and molecular evaluation of patient-derived colorectal cancer explants.

Uronis JM, Osada T, McCall S, Yang XY, Mantyh C, Morse MA, Lyerly HK, Clary BM, Hsu DS.

PLoS One. 2012;7(6):e38422. doi: 10.1371/journal.pone.0038422. Epub 2012 Jun 4.


NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signaling.

Allen IC, Wilson JE, Schneider M, Lich JD, Roberts RA, Arthur JC, Woodford RM, Davis BK, Uronis JM, Herfarth HH, Jobin C, Rogers AB, Ting JP.

Immunity. 2012 May 25;36(5):742-54. doi: 10.1016/j.immuni.2012.03.012. Epub 2012 Apr 12.


Mu opioid signaling protects against acute murine intestinal injury in a manner involving Stat3 signaling.

Goldsmith JR, Uronis JM, Jobin C.

Am J Pathol. 2011 Aug;179(2):673-83. doi: 10.1016/j.ajpath.2011.04.032. Epub 2011 Jun 13.


Gut microbial diversity is reduced by the probiotic VSL#3 and correlates with decreased TNBS-induced colitis.

Uronis JM, Arthur JC, Keku T, Fodor A, Carroll IM, Cruz ML, Appleyard CB, Jobin C.

Inflamm Bowel Dis. 2011 Jan;17(1):289-97. doi: 10.1002/ibd.21366.


The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer.

Allen IC, TeKippe EM, Woodford RM, Uronis JM, Holl EK, Rogers AB, Herfarth HH, Jobin C, Ting JP.

J Exp Med. 2010 May 10;207(5):1045-56. doi: 10.1084/jem.20100050. Epub 2010 Apr 12.


Microbes and colorectal cancer: is there a relationship?

Uronis JM, Jobin C.

Curr Oncol. 2009 Aug;16(4):22-4. No abstract available.


Modulation of the intestinal microbiota alters colitis-associated colorectal cancer susceptibility.

Uronis JM, Mühlbauer M, Herfarth HH, Rubinas TC, Jones GS, Jobin C.

PLoS One. 2009 Jun 24;4(6):e6026. doi: 10.1371/journal.pone.0006026.


Murine models of colorectal cancer.

Uronis JM, Threadgill DW.

Mamm Genome. 2009 May;20(5):261-8. doi: 10.1007/s00335-009-9186-5. Epub 2009 May 15. Review.


PKCalpha tumor suppression in the intestine is associated with transcriptional and translational inhibition of cyclin D1.

Pysz MA, Leontieva OV, Bateman NW, Uronis JM, Curry KJ, Threadgill DW, Janssen KP, Robine S, Velcich A, Augenlicht LH, Black AR, Black JD.

Exp Cell Res. 2009 May 1;315(8):1415-28. doi: 10.1016/j.yexcr.2009.02.002. Epub 2009 Feb 14.


Flat colorectal cancers are genetically determined and progress to invasion without going through a polypoid stage.

Uronis JM, Herfarth HH, Rubinas TC, Bissahoyo AC, Hanlon K, Threadgill DW.

Cancer Res. 2007 Dec 15;67(24):11594-600.


Protein kinase C signaling mediates a program of cell cycle withdrawal in the intestinal epithelium.

Frey MR, Clark JA, Leontieva O, Uronis JM, Black AR, Black JD.

J Cell Biol. 2000 Nov 13;151(4):763-78.

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