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Items: 17


A fully synthetic human Fab antibody library based on fixed VH/VL framework pairings with favorable biophysical properties.

Tiller T, Schuster I, Deppe D, Siegers K, Strohner R, Herrmann T, Berenguer M, Poujol D, Stehle J, Stark Y, Heßling M, Daubert D, Felderer K, Kaden S, Kölln J, Enzelberger M, Urlinger S.

MAbs. 2013 May-Jun;5(3):445-70. doi: 10.4161/mabs.24218. Epub 2013 Apr 9.


HuCAL PLATINUM, a synthetic Fab library optimized for sequence diversity and superior performance in mammalian expression systems.

Prassler J, Thiel S, Pracht C, Polzer A, Peters S, Bauer M, Nörenberg S, Stark Y, Kölln J, Popp A, Urlinger S, Enzelberger M.

J Mol Biol. 2011 Oct 14;413(1):261-78. doi: 10.1016/j.jmb.2011.08.012. Epub 2011 Aug 12.


In vitro affinity maturation of HuCAL antibodies: complementarity determining region exchange and RapMAT technology.

Prassler J, Steidl S, Urlinger S.

Immunotherapy. 2009 Jul;1(4):571-83. doi: 10.2217/imt.09.23. Review.


Fab MOR03268 triggers absorption shift of a diagnostic dye via packaging in a solvent-shielded Fab dimer interface.

Hillig RC, Urlinger S, Fanghänel J, Brocks B, Haenel C, Stark Y, Sülzle D, Svergun DI, Baesler S, Malawski G, Moosmayer D, Menrad A, Schirner M, Licha K.

J Mol Biol. 2008 Mar 14;377(1):206-19. doi: 10.1016/j.jmb.2007.12.071. Epub 2008 Jan 5.


The human combinatorial antibody library HuCAL GOLD combines diversification of all six CDRs according to the natural immune system with a novel display method for efficient selection of high-affinity antibodies.

Rothe C, Urlinger S, Löhning C, Prassler J, Stark Y, Jäger U, Hubner B, Bardroff M, Pradel I, Boss M, Bittlingmaier R, Bataa T, Frisch C, Brocks B, Honegger A, Urban M.

J Mol Biol. 2008 Feb 29;376(4):1182-200. doi: 10.1016/j.jmb.2007.12.018. Epub 2007 Dec 15.


Crystallization and molecular-replacement solution of a diagnostic fluorescent dye in complex with a specific Fab fragment.

Hillig RC, Baesler S, Urlinger S, Stark Y, Bauer S, Badock V, Huber M, Bahr I, Schirner M, Licha K.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Mar 1;63(Pt 3):217-23. Epub 2007 Feb 23.


Tetracycline-dependent gene regulation: combinations of transregulators yield a variety of expression windows.

Knott A, Garke K, Urlinger S, Guthmann J, Müller Y, Thellmann M, Hillen W.

Biotechniques. 2002 Apr;32(4):796, 798, 800 passim.


Tetracycline-inducible systems for Drosophila.

Stebbins MJ, Urlinger S, Byrne G, Bello B, Hillen W, Yin JC.

Proc Natl Acad Sci U S A. 2001 Sep 11;98(19):10775-80. Epub 2001 Aug 21.


Exploring the sequence space for tetracycline-dependent transcriptional activators: novel mutations yield expanded range and sensitivity.

Urlinger S, Baron U, Thellmann M, Hasan MT, Bujard H, Hillen W.

Proc Natl Acad Sci U S A. 2000 Jul 5;97(14):7963-8.


The p65 domain from NF-kappaB is an efficient human activator in the tetracycline-regulatable gene expression system.

Urlinger S, Helbl V, Guthmann J, Pook E, Grimm S, Hillen W.

Gene. 2000 Apr 18;247(1-2):103-10.


Tetracycline-inducible expression systems with reduced basal activity in mammalian cells.

Forster K, Helbl V, Lederer T, Urlinger S, Wittenburg N, Hillen W.

Nucleic Acids Res. 1999 Jan 15;27(2):708-10.


Down-regulation of the MHC class I antigen-processing machinery after oncogenic transformation of murine fibroblasts.

Seliger B, Harders C, Lohmann S, Momburg F, Urlinger S, Tampé R, Huber C.

Eur J Immunol. 1998 Jan;28(1):122-33.


Hyperexpression of transporter in antigen processing-1 (TAP-1) in thyroid glands affected by autoimmunity: a contributing factor to the breach of tolerance to thyroid antigens?

Sospedra M, Tolosa E, Armengol P, Ashhab Y, Urlinger S, Lucas-Martin A, Foz-Sala M, Jaraquemada D, Pujol-Borrell R.

Clin Exp Immunol. 1997 Jul;109(1):98-106.


Intracellular location, complex formation, and function of the transporter associated with antigen processing in yeast.

Urlinger S, Kuchler K, Meyer TH, Uebel S, Tampé R.

Eur J Biochem. 1997 Apr 15;245(2):266-72.


Interferon-gamma rescues HLA class Ia cell surface expression in term villous trophoblast cells by inducing synthesis of TAP proteins.

Rodriguez AM, Mallet V, Lenfant F, Arnaud J, Girr M, Urlinger S, Bensussan A, Le Bouteiller P.

Eur J Immunol. 1997 Jan;27(1):45-54.


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