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A Randomized, Double-Blind, Placebo-Controlled Study of Gelesis100: A Novel Nonsystemic Oral Hydrogel for Weight Loss.

Greenway FL, Aronne LJ, Raben A, Astrup A, Apovian CM, Hill JO, Kaplan LM, Fujioka K, Matejkova E, Svacina S, Luzi L, Gnessi L, Navas-Carretero S, Alfredo Martinez J, Still CD, Sannino A, Saponaro C, Demitri C, Urban LE, Leider H, Chiquette E, Ron ES, Zohar Y, Heshmati HM.

Obesity (Silver Spring). 2018 Nov 13. doi: 10.1002/oby.22347. [Epub ahead of print]


Safety differentiation: emerging competitive edge in drug development.

Uteng M, Urban L, Brees D, Muller PY, Kullak-Ublick GA, Bouchard P, Tougas G, Chibout SD.

Drug Discov Today. 2018 Sep 19. pii: S1359-6446(18)30190-9. doi: 10.1016/j.drudis.2018.09.009. [Epub ahead of print] Review.


Effect of a nonsystemic, orally administered hydrogel, GS100, on metformin pharmacokinetics.

Urban LE, Audet D, Ron ES, Sannino A, Zohar Y, Demitri C, Panteca E, Surano I, Heshmati HM.

Can J Physiol Pharmacol. 2018 Nov;96(11):1127-1131. doi: 10.1139/cjpp-2018-0123. Epub 2018 Aug 1.


Recently discovered interstitial cells "telocytes" as players in the pathogenesis of uterine leiomyomas.

Varga I, Klein M, Urban L, Danihel L Jr, Polak S, Danihel L Sr.

Med Hypotheses. 2018 Jan;110:64-67. doi: 10.1016/j.mehy.2017.11.003. Epub 2017 Nov 8.


Assessing the Effects of Water Deficit on Photosynthesis Using Parameters Derived from Measurements of Leaf Gas Exchange and of Chlorophyll a Fluorescence.

Urban L, Aarrouf J, Bidel LPR.

Front Plant Sci. 2017 Dec 14;8:2068. doi: 10.3389/fpls.2017.02068. eCollection 2017. Review.


Influence of Environmental Conditions and Genetic Background of Arabica Coffee (C. arabica L) on Leaf Rust (Hemileia vastatrix) Pathogenesis.

Toniutti L, Breitler JC, Etienne H, Campa C, Doulbeau S, Urban L, Lambot C, Pinilla JH, Bertrand B.

Front Plant Sci. 2017 Nov 28;8:2025. doi: 10.3389/fpls.2017.02025. eCollection 2017.


Post-exposure treatment with the oxime RS194B rapidly reactivates and reverses advanced symptoms of lethal inhaled paraoxon in macaques.

Rosenberg YJ, Wang J, Ooms T, Rajendran N, Mao L, Jiang X, Lees J, Urban L, Momper JD, Sepulveda Y, Shyong YJ, Taylor P.

Toxicol Lett. 2018 Sep 1;293:229-234. doi: 10.1016/j.toxlet.2017.10.025. Epub 2017 Nov 9.


Breast Cancer Screening: Updated Recommendations of the Brazilian College of Radiology and Diagnostic Imaging, Brazilian Breast Disease Society, and Brazilian Federation of Gynecological and Obstetrical Associations.

Urban LABD, Chala LF, Bauab SDP, Schaefer MB, Santos RPD, Maranhão NMA, Kefalas AL, Kalaf JM, Ferreira CAP, Canella EO, Peixoto JE, Amorim HLE, Camargo Junior HSA.

Rev Bras Ginecol Obstet. 2017 Oct;39(10):569-575. doi: 10.1055/s-0037-1606348. Epub 2017 Oct 16. No abstract available.


Adapting detection sensitivity based on evidence of irregular sinus arrhythmia to improve atrial fibrillation detection in insertable cardiac monitors.

Pürerfellner H, Sanders P, Sarkar S, Reisfeld E, Reiland J, Koehler J, Pokushalov E, Urban L, Dekker LRC.

Europace. 2017 Oct 3. doi: 10.1093/europace/eux272. [Epub ahead of print]


Breast cancer screening: updated recommendations of the Brazilian College of Radiology and Diagnostic Imaging, Brazilian Breast Disease Society, and Brazilian Federation of Gynecological and Obstetrical Associations.

Urban LABD, Chala LF, Bauab SDP, Schaefer MB, Dos Santos RP, Maranhão NMA, Kefalas AL, Kalaf JM, Ferreira CAP, Canella EO, Peixoto JE, de Amorim HLE, de Camargo Junior HSA.

Radiol Bras. 2017 Jul-Aug;50(4):244-249. doi: 10.1590/0100-3984.2017-0069.



P M White J, Cibelli M, Urban L, Nilius B, McGeown G, Nagy I.

Physiol Rev. 2017 Oct 1;97(4):1233-1234. doi: 10.1152/physrev.00020.2017. No abstract available.


Reverse translation of adverse event reports paves the way for de-risking preclinical off-targets.

Maciejewski M, Lounkine E, Whitebread S, Farmer P, DuMouchel W, Shoichet BK, Urban L.

Elife. 2017 Aug 8;6. pii: e25818. doi: 10.7554/eLife.25818.


Juvenile Coffee Leaves Acclimated to Low Light Are Unable to Cope with a Moderate Light Increase.

Campa C, Urban L, Mondolot L, Fabre D, Roques S, Lizzi Y, Aarrouf J, Doulbeau S, Breitler JC, Letrez C, Toniutti L, Bertrand B, La Fisca P, Bidel LPR, Etienne H.

Front Plant Sci. 2017 Jul 14;8:1126. doi: 10.3389/fpls.2017.01126. eCollection 2017.


The influence of pulsed light exposure mode on quality and bioactive compounds of fresh-cut mangoes.

de Almeida Lopes MM, Silva EO, Laurent S, Charles F, Urban L, de Miranda MRA.

J Food Sci Technol. 2017 Jul;54(8):2332-2340. doi: 10.1007/s13197-017-2673-x. Epub 2017 Jun 12.


Smoking History Predicts Sensitivity to PARP Inhibitor Veliparib in Patients with Advanced Non-Small Cell Lung Cancer.

Reck M, Blais N, Juhasz E, Gorbunova V, Jones CM, Urban L, Orlov S, Barlesi F, Kio E, Keilholz U, Qin Q, Qian J, Nickner C, Dziubinski J, Xiong H, Mittapalli RK, Dunbar M, Ansell P, He L, McKee M, Giranda V, Ramalingam SS.

J Thorac Oncol. 2017 Jul;12(7):1098-1108. doi: 10.1016/j.jtho.2017.04.010. Epub 2017 Apr 29.


Weight loss in videoconference and in-person iDiet weight loss programs in worksites and community groups.

Das SK, Brown C, Urban LE, O'Toole J, Gamache MMG, Weerasekara YK, Roberts SB.

Obesity (Silver Spring). 2017 Jun;25(6):1033-1041. doi: 10.1002/oby.21854. Epub 2017 Apr 28.


Association of nutrition club membership with markers of health: a cross sectional study.

Das SK, Vail TA, Lebrón-Torres N, Livingston KA, Roberts SB, Rogers GT, Gilhooly CH, Urban LE, Saltzman E, McKeown NM, Folta SC.

BMC Public Health. 2017 Apr 11;17(1):310. doi: 10.1186/s12889-017-4219-6.


Randomized, Placebo-Controlled, Phase II Study of Veliparib in Combination with Carboplatin and Paclitaxel for Advanced/Metastatic Non-Small Cell Lung Cancer.

Ramalingam SS, Blais N, Mazieres J, Reck M, Jones CM, Juhasz E, Urban L, Orlov S, Barlesi F, Kio E, Keiholz U, Qin Q, Qian J, Nickner C, Dziubinski J, Xiong H, Ansell P, McKee M, Giranda V, Gorbunova V.

Clin Cancer Res. 2017 Apr 15;23(8):1937-1944. doi: 10.1158/1078-0432.CCR-15-3069. Epub 2016 Oct 10.


Spatial Distribution of the Cannabinoid Type 1 and Capsaicin Receptors May Contribute to the Complexity of Their Crosstalk.

Chen J, Varga A, Selvarajah S, Jenes A, Dienes B, Sousa-Valente J, Kulik A, Veress G, Brain SD, Baker D, Urban L, Mackie K, Nagy I.

Sci Rep. 2016 Sep 22;6:33307. doi: 10.1038/srep33307.


Rolapitant improves quality of life of patients receiving highly or moderately emetogenic chemotherapy.

Chasen M, Urban L, Schnadig I, Rapoport B, Powers D, Arora S, Navari R, Schwartzberg L, Gridelli C.

Support Care Cancer. 2017 Jan;25(1):85-92. Epub 2016 Aug 24.


TRPV4: Molecular Conductor of a Diverse Orchestra.

White JP, Cibelli M, Urban L, Nilius B, McGeown JG, Nagy I.

Physiol Rev. 2016 Jul;96(3):911-73. doi: 10.1152/physrev.00016.2015. Review.


Telocytes (interstitial Cajal-like cells) in human Fallopian tubes.

Urban L, Miko M, Kajanova M, Bozikova S, Mrazova H, Varga I.

Bratisl Lek Listy. 2016;117(5):263-7.


Functional histology and possible clinical significance of recently discovered telocytes inside the female reproductive system.

Varga I, Urban L, Kajanová M, Polák Š.

Arch Gynecol Obstet. 2016 Aug;294(2):417-22. doi: 10.1007/s00404-016-4106-x. Epub 2016 May 3. Review.


Secondary pharmacology: screening and interpretation of off-target activities - focus on translation.

Whitebread S, Dumotier B, Armstrong D, Fekete A, Chen S, Hartmann A, Muller PY, Urban L.

Drug Discov Today. 2016 Aug;21(8):1232-42. doi: 10.1016/j.drudis.2016.04.021. Epub 2016 Apr 29. Review.


Understanding the physiological effects of UV-C light and exploiting its agronomic potential before and after harvest.

Urban L, Charles F, de Miranda MRA, Aarrouf J.

Plant Physiol Biochem. 2016 Aug;105:1-11. doi: 10.1016/j.plaphy.2016.04.004. Epub 2016 Apr 4. Review.


The relation between oxidative stress biomarkers and atrial fibrillation after pulmonary veins isolation.

Böhm A, Tothova L, Urban L, Slezak P, Bacharova L, Musil P, Hatala R.

J Electrocardiol. 2016 May-Jun;49(3):423-8. doi: 10.1016/j.jelectrocard.2016.03.007. Epub 2016 Mar 7.


[Functional morphology of recently discovered telocytes inside the female reproductive system].

Božíková S, Urban L, Kajanová M, Béder I, Pohlodek K, Varga I.

Ceska Gynekol. 2016 Jan;81(1):31-7. Czech.


Implications of Dynamic Occupancy, Binding Kinetics, and Channel Gating Kinetics for hERG Blocker Safety Assessment and Mitigation.

Pearlstein RA, MacCannell KA, Erdemli G, Yeola S, Helmlinger G, Hu QY, Farid R, Egan W, Whitebread S, Springer C, Beck J, Wang HR, Maciejewski M, Urban L, Duca JS.

Curr Top Med Chem. 2016;16(16):1792-818. Review.


Fine-needle aspiration of axillary lymph nodes: a change of paradigm in the approach to axillary compromise?

Urban LA.

Radiol Bras. 2016 Jan-Feb;49(1):IX. doi: 10.1590/0100-3984.2016.49.1e3. No abstract available.


Energy Contents of Frequently Ordered Restaurant Meals and Comparison with Human Energy Requirements and U.S. Department of Agriculture Database Information: A Multisite Randomized Study.

Urban LE, Weber JL, Heyman MB, Schichtl RL, Verstraete S, Lowery NS, Das SK, Schleicher MM, Rogers G, Economos C, Masters WA, Roberts SB.

J Acad Nutr Diet. 2016 Apr;116(4):590-8.e6. doi: 10.1016/j.jand.2015.11.009. Epub 2016 Jan 20.


The Potential of the MAGIC TOM Parental Accessions to Explore the Genetic Variability in Tomato Acclimation to Repeated Cycles of Water Deficit and Recovery.

Ripoll J, Urban L, Bertin N.

Front Plant Sci. 2016 Jan 5;6:1172. doi: 10.3389/fpls.2015.01172. eCollection 2015.


Detection of occult paroxysmal atrial fibrilation by implantable long-term electrocardiographic monitoring in cryptogenic stroke and transient ischemic attack population: a study protocol for prospective matched cohort study.

Petrovičová A, Kurča E, Brozman M, Hasilla J, Vahala P, Blaško P, Andrášová A, Hatala R, Urban L, Sivák Š.

BMC Cardiovasc Disord. 2015 Dec 3;15:160. doi: 10.1186/s12872-015-0160-8.


Water deficit effects on tomato quality depend on fruit developmental stage and genotype.

Ripoll J, Urban L, Brunel B, Bertin N.

J Plant Physiol. 2016 Jan 15;190:26-35. doi: 10.1016/j.jplph.2015.10.006. Epub 2015 Nov 14.


Occurrence of symptoms after catheter ablation of atrial fibrillation.

Bou Ezzeddine H, Vachulova A, Svetlosak M, Urban L, Hlivak P, Margitfalvi P, Bernat V, Gladisova K, Sasov M, Hatala R.

Bratisl Lek Listy. 2015;116(8):461-4.


Safety and efficacy of rolapitant for prevention of chemotherapy-induced nausea and vomiting after administration of cisplatin-based highly emetogenic chemotherapy in patients with cancer: two randomised, active-controlled, double-blind, phase 3 trials.

Rapoport BL, Chasen MR, Gridelli C, Urban L, Modiano MR, Schnadig ID, Poma A, Arora S, Kansra V, Schwartzberg LS, Navari RM.

Lancet Oncol. 2015 Sep;16(9):1079-1089. doi: 10.1016/S1470-2045(15)00035-2. Epub 2015 Aug 10.


Safety and efficacy of rolapitant for prevention of chemotherapy-induced nausea and vomiting after administration of moderately emetogenic chemotherapy or anthracycline and cyclophosphamide regimens in patients with cancer: a randomised, active-controlled, double-blind, phase 3 trial.

Schwartzberg LS, Modiano MR, Rapoport BL, Chasen MR, Gridelli C, Urban L, Poma A, Arora S, Navari RM, Schnadig ID.

Lancet Oncol. 2015 Sep;16(9):1071-1078. doi: 10.1016/S1470-2045(15)00034-0. Epub 2015 Aug 10.


A highly stable minimally processed plant-derived recombinant acetylcholinesterase for nerve agent detection in adverse conditions.

Rosenberg YJ, Walker J, Jiang X, Donahue S, Robosky J, Sack M, Lees J, Urban L.

Sci Rep. 2015 Aug 13;5:13247. doi: 10.1038/srep13247.


Diagnostic Accuracy of the Slump Test for Identifying Neuropathic Pain in the Lower Limb.

Urban LM, MacNeil BJ.

J Orthop Sports Phys Ther. 2015 Aug;45(8):596-603. doi: 10.2519/jospt.2015.5414. Epub 2015 Jun 24.


Integrated risk assessment of suicidal ideation and behavior in drug development.

Muller PY, Dambach D, Gemzik B, Hartmann A, Ratcliffe S, Trendelenburg C, Urban L.

Drug Discov Today. 2015 Sep;20(9):1135-42. doi: 10.1016/j.drudis.2015.05.010. Epub 2015 May 27. Review.


Pharmacokinetics and immunogenicity of broadly neutralizing HIV monoclonal antibodies in macaques.

Rosenberg Y, Sack M, Montefiori D, Labranche C, Lewis M, Urban L, Mao L, Fischer R, Jiang X.

PLoS One. 2015 Mar 25;10(3):e0120451. doi: 10.1371/journal.pone.0120451. eCollection 2015.


Temporal trends in fast-food restaurant energy, sodium, saturated fat, and trans fat content, United States, 1996-2013.

Urban LE, Roberts SB, Fierstein JL, Gary CE, Lichtenstein AH.

Prev Chronic Dis. 2014 Dec 31;11:E229. doi: 10.5888/pcd11.140202.


Sodium, saturated fat, and trans fat content per 1,000 kilocalories: temporal trends in fast-food restaurants, United States, 2000-2013.

Urban LE, Roberts SB, Fierstein JL, Gary CE, Lichtenstein AH.

Prev Chronic Dis. 2014 Dec 31;11:E228. doi: 10.5888/pcd11.140335.


Pilot randomized trial demonstrating reversal of obesity-related abnormalities in reward system responsivity to food cues with a behavioral intervention.

Deckersbach T, Das SK, Urban LE, Salinardi T, Batra P, Rodman AM, Arulpragasam AR, Dougherty DD, Roberts SB.

Nutr Diabetes. 2014 Sep 1;4:e129. doi: 10.1038/nutd.2014.26.


Salt stress mitigation by seed priming with UV-C in lettuce plants: growth, antioxidant activity and phenolic compounds.

Ouhibi C, Attia H, Rebah F, Msilini N, Chebbi M, Aarrouf J, Urban L, Lachaal M.

Plant Physiol Biochem. 2014 Oct;83:126-33. doi: 10.1016/j.plaphy.2014.07.019. Epub 2014 Aug 1.


Hydrogen bonding of nitroxide spin labels in membrane proteins.

Gast P, Herbonnet RT, Klare J, Nalepa A, Rickert C, Stellinga D, Urban L, Möbius K, Savitsky A, Steinhoff HJ, Groenen EJ.

Phys Chem Chem Phys. 2014 Aug 14;16(30):15910-6. doi: 10.1039/c4cp01741b.


P-wave evidence as a method for improving algorithm to detect atrial fibrillation in insertable cardiac monitors.

Pürerfellner H, Pokushalov E, Sarkar S, Koehler J, Zhou R, Urban L, Hindricks G.

Heart Rhythm. 2014 Sep;11(9):1575-83. doi: 10.1016/j.hrthm.2014.06.006. Epub 2014 Jun 6.


[New views on the functional morphology of human clitoris].

Miko M, Urban L, Kajanová M, Polák S, Varga I.

Ceska Gynekol. 2014 Apr;79(2):147-55. Review. Czech.


Independent, additive effects of five dietary variables on ad libitum energy intake in a residential study.

Urban LE, McCrory MA, Rasmussen H, Greenberg AS, Fuss PJ, Saltzman E, Roberts SB.

Obesity (Silver Spring). 2014 Sep;22(9):2018-25. doi: 10.1002/oby.20798. Epub 2014 May 26.


Water shortage and quality of fleshy fruits--making the most of the unavoidable.

Ripoll J, Urban L, Staudt M, Lopez-Lauri F, Bidel LP, Bertin N.

J Exp Bot. 2014 Aug;65(15):4097-117. doi: 10.1093/jxb/eru197. Epub 2014 May 12. Review.


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