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Items: 1 to 50 of 257

1.

Bacillus thuringiensis Cry5B protein as a new pan-hookworm cure.

Hu Y, Nguyen TT, Lee ACY, Urban JF Jr, Miller MM, Zhan B, Koch DJ, Noon JB, Abraham A, Fujiwara RT, Bowman DD, Ostroff GR, Aroian RV.

Int J Parasitol Drugs Drug Resist. 2018 May 4;8(2):287-294. doi: 10.1016/j.ijpddr.2018.05.001. [Epub ahead of print]

2.

Activation of intestinal tuft cell-expressed Sucnr1 triggers type 2 immunity in the mouse small intestine.

Lei W, Ren W, Ohmoto M, Urban JF Jr, Matsumoto I, Margolskee RF, Jiang P.

Proc Natl Acad Sci U S A. 2018 May 22;115(21):5552-5557. doi: 10.1073/pnas.1720758115. Epub 2018 May 7.

PMID:
29735652
3.

Bcl11b is essential for licensing Th2 differentiation during helminth infection and allergic asthma.

Lorentsen KJ, Cho JJ, Luo X, Zuniga AN, Urban JF Jr, Zhou L, Gharaibeh R, Jobin C, Kladde MP, Avram D.

Nat Commun. 2018 Apr 26;9(1):1679. doi: 10.1038/s41467-018-04111-0.

4.

The Ossabaw Pig Is a Suitable Translational Model to Evaluate Dietary Patterns and Coronary Artery Disease Risk.

Matthan NR, Solano-Aguilar G, Meng H, Lamon-Fava S, Goldbaum A, Walker ME, Jang S, Lakshman S, Molokin A, Xie Y, Beshah E, Stanley J, Urban JF Jr, Lichtenstein AH.

J Nutr. 2018 Apr 1;148(4):542-551. doi: 10.1093/jn/nxy002.

PMID:
29659954
5.

Impact of Micronutrients on the Immune Response of Animals.

Smith AD, Panickar KS, Urban JF Jr, Dawson HD.

Annu Rev Anim Biosci. 2018 Feb 15;6:227-254. doi: 10.1146/annurev-animal-022516-022914.

PMID:
29447473
6.

B1 Cell IgE Impedes Mast Cell-Mediated Enhancement of Parasite Expulsion through B2 IgE Blockade.

Martin RK, Damle SR, Valentine YA, Zellner MP, James BN, Lownik JC, Luker AJ, Davis EH, DeMeules MM, Khandjian LM, Finkelman FD, Urban JF Jr, Conrad DH.

Cell Rep. 2018 Feb 13;22(7):1824-1834. doi: 10.1016/j.celrep.2018.01.048.

7.

S1P-dependent interorgan trafficking of group 2 innate lymphoid cells supports host defense.

Huang Y, Mao K, Chen X, Sun MA, Kawabe T, Li W, Usher N, Zhu J, Urban JF Jr, Paul WE, Germain RN.

Science. 2018 Jan 5;359(6371):114-119. doi: 10.1126/science.aam5809.

PMID:
29302015
8.

Flavanol-Rich Cocoa Powder Interacts with Lactobacillus rhamnossus LGG to Alter the Antibody Response to Infection with the Parasitic Nematode Ascaris suum.

Jang S, Lakshman S, Beshah E, Xie Y, Molokin A, Vinyard BT, Urban JF, Davis CD, Solano-Aguilar GI.

Nutrients. 2017 Oct 12;9(10). pii: E1113. doi: 10.3390/nu9101113.

9.

The porcine translational research database: a manually curated, genomics and proteomics-based research resource.

Dawson HD, Chen C, Gaynor B, Shao J, Urban JF Jr.

BMC Genomics. 2017 Aug 22;18(1):643. doi: 10.1186/s12864-017-4009-7.

10.

IL-4 up-regulates cyclooxygenase-1 expression in macrophages.

Shay AE, Diwakar BT, Guan BJ, Narayan V, Urban JF Jr, Prabhu KS.

J Biol Chem. 2017 Sep 1;292(35):14544-14555. doi: 10.1074/jbc.M117.785014. Epub 2017 Jul 6.

PMID:
28684424
11.

Ancylostoma ailuropodae n. sp. (Nematoda: Ancylostomatidae), a new hookworm parasite isolated from wild giant pandas in Southwest China.

Xie Y, Hoberg EP, Yang Z, Urban JF Jr, Yang G.

Parasit Vectors. 2017 Jun 2;10(1):277. doi: 10.1186/s13071-017-2209-2.

12.

Downregulation of E Protein Activity Augments an ILC2 Differentiation Program in the Thymus.

Wang HC, Qian L, Zhao Y, Mengarelli J, Adrianto I, Montgomery CG, Urban JF Jr, Fung KM, Sun XH.

J Immunol. 2017 Apr 15;198(8):3149-3156. doi: 10.4049/jimmunol.1602009. Epub 2017 Mar 3.

13.

Neuroimmune Modulation of Gut Function.

Shea-Donohue T, Urban JF Jr.

Handb Exp Pharmacol. 2017;239:247-267. doi: 10.1007/164_2016_109. Review.

PMID:
28035531
14.

Microfluidic platform for electrophysiological recordings from host-stage hookworm and Ascaris suum larvae: A new tool for anthelmintic research.

Weeks JC, Roberts WM, Robinson KJ, Keaney M, Vermeire JJ, Urban JF Jr, Lockery SR, Hawdon JM.

Int J Parasitol Drugs Drug Resist. 2016 Dec;6(3):314-328. doi: 10.1016/j.ijpddr.2016.08.001. Epub 2016 Sep 15.

15.

Critical Role for Interleukin-25 in Host Protective Th2 Memory Response against Heligmosomoides polygyrus bakeri.

Pei C, Zhao C, Wang AJ, Fan AX, Grinchuk V, Smith A, Sun R, Xie Y, Lu N, Urban JF Jr, Shea-Donohue T, Zhao A, Yang Z.

Infect Immun. 2016 Nov 18;84(12):3328-3337. Print 2016 Dec.

16.

Downregulation of the Syk Signaling Pathway in Intestinal Dendritic Cells Is Sufficient To Induce Dendritic Cells That Inhibit Colitis.

Hang L, Blum AM, Kumar S, Urban JF Jr, Mitreva M, Geary TG, Jardim A, Stevenson MM, Lowell CA, Weinstock JV.

J Immunol. 2016 Oct 1;197(7):2948-57. doi: 10.4049/jimmunol.1600063. Epub 2016 Aug 24.

17.

Critical role of fatty acid metabolism in ILC2-mediated barrier protection during malnutrition and helminth infection.

Wilhelm C, Harrison OJ, Schmitt V, Pelletier M, Spencer SP, Urban JF Jr, Ploch M, Ramalingam TR, Siegel RM, Belkaid Y.

J Exp Med. 2016 Jul 25;213(8):1409-18. doi: 10.1084/jem.20151448. Epub 2016 Jul 18.

18.

An in-depth comparison of the porcine, murine and human inflammasomes; lessons from the porcine genome and transcriptome.

Dawson HD, Smith AD, Chen C, Urban JF Jr.

Vet Microbiol. 2017 Apr;202:2-15. doi: 10.1016/j.vetmic.2016.05.013. Epub 2016 Jun 4.

PMID:
27321134
19.

Type 3 muscarinic receptors contribute to intestinal mucosal homeostasis and clearance of Nippostrongylus brasiliensis through induction of TH2 cytokines.

McLean LP, Smith A, Cheung L, Urban JF Jr, Sun R, Grinchuk V, Desai N, Zhao A, Raufman JP, Shea-Donohue T.

Am J Physiol Gastrointest Liver Physiol. 2016 Jul 1;311(1):G130-41. doi: 10.1152/ajpgi.00461.2014. Epub 2016 May 12.

20.

Developmental Acquisition of Regulomes Underlies Innate Lymphoid Cell Functionality.

Shih HY, Sciumè G, Mikami Y, Guo L, Sun HW, Brooks SR, Urban JF Jr, Davis FP, Kanno Y, O'Shea JJ.

Cell. 2016 May 19;165(5):1120-1133. doi: 10.1016/j.cell.2016.04.029. Epub 2016 May 5.

21.

Acidic chitinase primes the protective immune response to gastrointestinal nematodes.

Vannella KM, Ramalingam TR, Hart KM, de Queiroz Prado R, Sciurba J, Barron L, Borthwick LA, Smith AD, Mentink-Kane M, White S, Thompson RW, Cheever AW, Bock K, Moore I, Fitz LJ, Urban JF Jr, Wynn TA.

Nat Immunol. 2016 May;17(5):538-44. doi: 10.1038/ni.3417. Epub 2016 Apr 4.

22.

Flavanol-Enriched Cocoa Powder Alters the Intestinal Microbiota, Tissue and Fluid Metabolite Profiles, and Intestinal Gene Expression in Pigs.

Jang S, Sun J, Chen P, Lakshman S, Molokin A, Harnly JM, Vinyard BT, Urban JF Jr, Davis CD, Solano-Aguilar G.

J Nutr. 2016 Apr;146(4):673-80. doi: 10.3945/jn.115.222968. Epub 2016 Mar 2.

23.

The effect of helminth infection on the microbial composition and structure of the caprine abomasal microbiome.

Li RW, Li W, Sun J, Yu P, Baldwin RL, Urban JF.

Sci Rep. 2016 Feb 8;6:20606. doi: 10.1038/srep20606.

24.

Interleukin-13 Receptor α1-Dependent Responses in the Intestine Are Critical to Parasite Clearance.

Sun R, Urban JF Jr, Notari L, Vanuytsel T, Madden KB, Bohl JA, Ramalingam TR, Wynn TA, Zhao A, Shea-Donohue T.

Infect Immun. 2016 Mar 24;84(4):1032-1044. doi: 10.1128/IAI.00990-15. Print 2016 Apr.

25.

Migratory CD103+ dendritic cells suppress helminth-driven type 2 immunity through constitutive expression of IL-12.

Everts B, Tussiwand R, Dreesen L, Fairfax KC, Huang SC, Smith AM, O'Neill CM, Lam WY, Edelson BT, Urban JF Jr, Murphy KM, Pearce EJ.

J Exp Med. 2016 Jan 11;213(1):35-51. doi: 10.1084/jem.20150235. Epub 2015 Dec 28.

26.

Erratum to: Type 2 immunity-dependent reduction of segmented filamentous bacteria in mice infected with the helminthic parasite Nippostrongylus brasiliensis.

Fricke WF, Song Y, Wang AJ, Smith A, Grinchuk V, Pei C, Ma B, Lu N, Urban JF Jr, Shea-Donohue T, Zhao A.

Microbiome. 2015 Dec 21;3:77. doi: 10.1186/s40168-015-0142-1. No abstract available.

27.

Selenoprotein Expression in Macrophages Is Critical for Optimal Clearance of Parasitic Helminth Nippostrongylus brasiliensis.

Nelson SM, Shay AE, James JL, Carlson BA, Urban JF Jr, Prabhu KS.

J Biol Chem. 2016 Feb 5;291(6):2787-98. doi: 10.1074/jbc.M115.684738. Epub 2015 Dec 7.

28.

Intrinsic functional defects of type 2 innate lymphoid cells impair innate allergic inflammation in promyelocytic leukemia zinc finger (PLZF)-deficient mice.

Verhoef PA, Constantinides MG, McDonald BD, Urban JF Jr, Sperling AI, Bendelac A.

J Allergy Clin Immunol. 2016 Feb;137(2):591-600.e1. doi: 10.1016/j.jaci.2015.07.050. Epub 2015 Oct 23.

29.

IL-25 or IL-17E Protects against High-Fat Diet-Induced Hepatic Steatosis in Mice Dependent upon IL-13 Activation of STAT6.

Wang AJ, Yang Z, Grinchuk V, Smith A, Qin B, Lu N, Wang D, Wang H, Ramalingam TR, Wynn TA, Urban JF Jr, Shea-Donohue T, Zhao A.

J Immunol. 2015 Nov 15;195(10):4771-80. doi: 10.4049/jimmunol.1500337. Epub 2015 Sep 30.

30.

Type 2 immunity-dependent reduction of segmented filamentous bacteria in mice infected with the helminthic parasite Nippostrongylus brasiliensis.

Fricke WF, Song Y, Wang AJ, Smith A, Grinchuk V, Mongodin E, Pei C, Ma B, Lu N, Urban JF Jr, Shea-Donohue T, Zhao A.

Microbiome. 2015 Sep 17;3:40. doi: 10.1186/s40168-015-0103-8. Erratum in: Microbiome. 2015;3:77. Mongodin, Emmanuel [Added].

31.

Innate immunological function of TH2 cells in vivo.

Guo L, Huang Y, Chen X, Hu-Li J, Urban JF Jr, Paul WE.

Nat Immunol. 2015 Oct;16(10):1051-9. doi: 10.1038/ni.3244. Epub 2015 Aug 31.

32.

Type 3 Muscarinic Receptors Contribute to Clearance of Citrobacter rodentium.

McLean LP, Smith A, Cheung L, Sun R, Grinchuk V, Vanuytsel T, Desai N, Urban JF Jr, Zhao A, Raufman JP, Shea-Donohue T.

Inflamm Bowel Dis. 2015 Aug;21(8):1860-71. doi: 10.1097/MIB.0000000000000408.

33.

Resource limitation alters the consequences of co-infection for both hosts and parasites.

Budischak SA, Sakamoto K, Megow LC, Cummings KR, Urban JF Jr, Ezenwa VO.

Int J Parasitol. 2015 Jun;45(7):455-63. doi: 10.1016/j.ijpara.2015.02.005. Epub 2015 Mar 24.

PMID:
25812832
34.

Immune antibodies and helminth products drive CXCR2-dependent macrophage-myofibroblast crosstalk to promote intestinal repair.

Esser-von Bieren J, Volpe B, Sutherland DB, Bürgi J, Verbeek JS, Marsland BJ, Urban JF Jr, Harris NL.

PLoS Pathog. 2015 Mar 25;11(3):e1004778. doi: 10.1371/journal.ppat.1004778. eCollection 2015 Mar.

35.

Impact of a high-fat meal on assessment of clopidogrel-induced platelet inhibition in healthy subjects.

Dobesh PP, Urban JF, Shurmur SW, Oestreich JH.

Thromb J. 2015 Jan 23;13(1):3. doi: 10.1186/s12959-014-0033-x. eCollection 2015.

36.

Immune and inflammatory responses in pigs infected with Trichuris suis and Oesophagostomum dentatum.

Andreasen A, Petersen HH, Kringel H, Iburg TM, Skovgaard K, Dawson H, Urban JF Jr, Thamsborg SM.

Vet Parasitol. 2015 Jan 30;207(3-4):249-58. doi: 10.1016/j.vetpar.2014.12.005. Epub 2014 Dec 15.

PMID:
25576439
37.

IL-25-responsive, lineage-negative KLRG1(hi) cells are multipotential 'inflammatory' type 2 innate lymphoid cells.

Huang Y, Guo L, Qiu J, Chen X, Hu-Li J, Siebenlist U, Williamson PR, Urban JF Jr, Paul WE.

Nat Immunol. 2015 Feb;16(2):161-9. doi: 10.1038/ni.3078. Epub 2014 Dec 22.

38.

Intestinal helminths regulate lethal acute graft-versus-host disease and preserve the graft-versus-tumor effect in mice.

Li Y, Chen HL, Bannick N, Henry M, Holm AN, Metwali A, Urban JF Jr, Rothman PB, Weiner GJ, Blazar BR, Elliott DE, Ince MN.

J Immunol. 2015 Feb 1;194(3):1011-20. doi: 10.4049/jimmunol.1303099. Epub 2014 Dec 19.

39.

A high fat, high cholesterol diet leads to changes in metabolite patterns in pigs--a metabolomic study.

Sun J, Monagas M, Jang S, Molokin A, Harnly JM, Urban JF Jr, Solano-Aguilar G, Chen P.

Food Chem. 2015 Apr 15;173:171-8. doi: 10.1016/j.foodchem.2014.09.161. Epub 2014 Oct 7.

40.

Neutrophils prime a long-lived effector macrophage phenotype that mediates accelerated helminth expulsion.

Chen F, Wu W, Millman A, Craft JF, Chen E, Patel N, Boucher JL, Urban JF Jr, Kim CC, Gause WC.

Nat Immunol. 2014 Oct;15(10):938-46. doi: 10.1038/ni.2984. Epub 2014 Aug 31.

41.

Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages.

Huang SC, Everts B, Ivanova Y, O'Sullivan D, Nascimento M, Smith AM, Beatty W, Love-Gregory L, Lam WY, O'Neill CM, Yan C, Du H, Abumrad NA, Urban JF Jr, Artyomov MN, Pearce EL, Pearce EJ.

Nat Immunol. 2014 Sep;15(9):846-55. doi: 10.1038/ni.2956. Epub 2014 Aug 3.

42.

Role of macrophages in the altered epithelial function during a type 2 immune response induced by enteric nematode infection.

Notari L, Riera DC, Sun R, Bohl JA, McLean LP, Madden KB, van Rooijen N, Vanuytsel T, Urban JF Jr, Zhao A, Shea-Donohue T.

PLoS One. 2014 Jan 23;9(1):e84763. doi: 10.1371/journal.pone.0084763. eCollection 2014.

43.

Adaptation of innate lymphoid cells to a micronutrient deficiency promotes type 2 barrier immunity.

Spencer SP, Wilhelm C, Yang Q, Hall JA, Bouladoux N, Boyd A, Nutman TB, Urban JF Jr, Wang J, Ramalingam TR, Bhandoola A, Wynn TA, Belkaid Y.

Science. 2014 Jan 24;343(6169):432-7. doi: 10.1126/science.1247606.

44.

Genetic deletion of IL-25 (IL-17E) confers resistance to dextran sulfate sodium-induced colitis in mice.

Wang AJ, Smith A, Li Y, Urban JF Jr, Ramalingam TR, Wynn TA, Lu N, Shea-Donohue T, Yang Z, Zhao A.

Cell Biosci. 2014 Nov 26;4:72. doi: 10.1186/2045-3701-4-72. eCollection 2014.

45.

Myeloid-derived suppressor cells enhance IgE-mediated mast cell responses.

Morales JK, Saleem SJ, Martin RK, Saunders BL, Barnstein BO, Faber TW, Pullen NA, Kolawole EM, Brooks KB, Norton SK, Sturgill J, Graham L, Bear HD, Urban JF Jr, Lantz CS, Conrad DH, Ryan JJ.

J Leukoc Biol. 2014 Apr;95(4):643-50. doi: 10.1189/jlb.0913510. Epub 2013 Dec 12.

46.

The distinctive germinal center phase of IgE+ B lymphocytes limits their contribution to the classical memory response.

He JS, Meyer-Hermann M, Xiangying D, Zuan LY, Jones LA, Ramakrishna L, de Vries VC, Dolpady J, Aina H, Joseph S, Narayanan S, Subramaniam S, Puthia M, Wong G, Xiong H, Poidinger M, Urban JF, Lafaille JJ, Curotto de Lafaille MA.

J Exp Med. 2013 Nov 18;210(12):2755-71. doi: 10.1084/jem.20131539. Epub 2013 Nov 11.

47.

Feeding probiotic Lactobacillus paracasei to Ossabaw pigs on a high-fat diet prevents cholesteryl-ester accumulation and LPS modulation of the Liver X receptor and inflammatory axis in alveolar macrophages.

Trasino SE, Dawson HD, Urban JF Jr, Wang TT, Solano-Aguilar G.

J Nutr Biochem. 2013 Nov;24(11):1931-9. doi: 10.1016/j.jnutbio.2013.06.001. Epub 2013 Sep 20.

PMID:
24060267
48.

An extensive comparison of the effect of anthelmintic classes on diverse nematodes.

Hu Y, Ellis BL, Yiu YY, Miller MM, Urban JF, Shi LZ, Aroian RV.

PLoS One. 2013 Jul 15;8(7):e70702. doi: 10.1371/journal.pone.0070702. Print 2013.

49.

Bacillus thuringiensis-derived Cry5B has potent anthelmintic activity against Ascaris suum.

Urban JF Jr, Hu Y, Miller MM, Scheib U, Yiu YY, Aroian RV.

PLoS Negl Trop Dis. 2013 Jun 20;7(6):e2263. doi: 10.1371/journal.pntd.0002263. Print 2013.

50.

Comparative nontargeted profiling of metabolic changes in tissues and biofluids in high-fat diet-fed Ossabaw pig.

Hanhineva K, Barri T, Kolehmainen M, Pekkinen J, Pihlajamäki J, Vesterbacka A, Solano-Aguilar G, Mykkänen H, Dragsted LO, Urban JF Jr, Poutanen K.

J Proteome Res. 2013 Sep 6;12(9):3980-92. doi: 10.1021/pr400257d. Epub 2013 Aug 6.

PMID:
23805856

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