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Items: 1 to 50 of 63

1.

Innate and adaptive nasal mucosal immune responses following experimental human pneumococcal colonization.

Jochems SP, de Ruiter K, Solórzano C, Voskamp A, Mitsi E, Nikolaou E, Carniel BF, Pojar S, German EL, Reiné J, Soares-Schanoski A, Hill H, Robinson R, Hyder-Wright AD, Weight CM, Durrenberger PF, Heyderman RS, Gordon SB, Smits HH, Urban BC, Rylance J, Collins AM, Wilkie MD, Lazarova L, Leong SC, Yazdanbakhsh M, Ferreira DM.

J Clin Invest. 2019 Jul 30;130. pii: 128865. doi: 10.1172/JCI128865.

2.

Antigenic cartography of immune responses to Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1).

Tuju J, Mackinnon MJ, Abdi AI, Karanja H, Musyoki JN, Warimwe GM, Gitau EN, Marsh K, Bull PC, Urban BC.

PLoS Pathog. 2019 Jul 1;15(7):e1007870. doi: 10.1371/journal.ppat.1007870. eCollection 2019 Jul. Erratum in: PLoS Pathog. 2019 Aug 15;15(8):e1008018.

3.

Immune Responses to the Sexual Stages of Plasmodium falciparum Parasites.

Kengne-Ouafo JA, Sutherland CJ, Binka FN, Awandare GA, Urban BC, Dinko B.

Front Immunol. 2019 Feb 11;10:136. doi: 10.3389/fimmu.2019.00136. eCollection 2019. Review.

4.

Gametocyte Development and Carriage in Ghanaian Individuals with Uncomplicated Plasmodium falciparum Malaria.

Dinko B, Ansah F, Agyare-Kwabi C, Tagboto S, Amoah LE, Urban BC, Sutherland CJ, Awandare GA, Williamson KC, Binka FN, Deitsch KW.

Am J Trop Med Hyg. 2018 Jul;99(1):57-64. doi: 10.4269/ajtmh.18-0077. Epub 2018 Apr 19.

5.

Proportions of circulating follicular helper T cells are reduced and correlate with memory B cells in HIV-infected children.

Muema DM, Macharia GN, Olusola BA, Hassan AS, Fegan GW, Berkley JA, Urban BC, Nduati EW.

PLoS One. 2017 Apr 26;12(4):e0175570. doi: 10.1371/journal.pone.0175570. eCollection 2017.

6.

The CSF Immune Response in HIV-1-Associated Cryptococcal Meningitis: Macrophage Activation, Correlates of Disease Severity, and Effect of Antiretroviral Therapy.

Scriven JE, Graham LM, Schutz C, Scriba TJ, Wilkinson KA, Wilkinson RJ, Boulware DR, Urban BC, Meintjes G, Lalloo DG.

J Acquir Immune Defic Syndr. 2017 Jul 1;75(3):299-307. doi: 10.1097/QAI.0000000000001382.

7.

Glycan-independent binding and internalization of human IgM to FCMR, its cognate cellular receptor.

Lloyd KA, Wang J, Urban BC, Czajkowsky DM, Pleass RJ.

Sci Rep. 2017 Feb 23;7:42989. doi: 10.1038/srep42989.

8.

HIV-Exposed Uninfected Infants Show Robust Memory B-Cell Responses in Spite of a Delayed Accumulation of Memory B Cells: an Observational Study in the First 2 Years of Life.

Nduati EW, Nkumama IN, Gambo FK, Muema DM, Knight MG, Hassan AS, Jahangir MN, Etyang TJ, Berkley JA, Urban BC.

Clin Vaccine Immunol. 2016 Jul 5;23(7):576-85. doi: 10.1128/CVI.00149-16. Print 2016 Jul.

9.

A recombinant two-module form of human properdin is an inhibitor of the complement alternative pathway.

Kouser L, Abdul-Aziz M, Tsolaki AG, Singhal D, Schwaeble WJ, Urban BC, Khan HA, Sim RB, Kishore U.

Mol Immunol. 2016 May;73:76-87. doi: 10.1016/j.molimm.2016.03.005. Epub 2016 Apr 6.

10.

Increased adhesion of Plasmodium falciparum infected erythrocytes to ICAM-1 in children with acute intestinal injury.

Church JA, Nyamako L, Olupot-Olupot P, Maitland K, Urban BC.

Malar J. 2016 Feb 1;15:54. doi: 10.1186/s12936-016-1110-3.

11.

Candidate Antimetastasis Drugs Suppress the Metastatic Capacity of Breast Cancer Cells by Reducing Membrane Fluidity.

Zhao W, Prijic S, Urban BC, Tisza MJ, Zuo Y, Li L, Tan Z, Chen X, Mani SA, Chang JT.

Cancer Res. 2016 Apr 1;76(7):2037-49. doi: 10.1158/0008-5472.CAN-15-1970. Epub 2016 Jan 29.

12.

A Glucuronoxylomannan-Associated Immune Signature, Characterized by Monocyte Deactivation and an Increased Interleukin 10 Level, Is a Predictor of Death in Cryptococcal Meningitis.

Scriven JE, Graham LM, Schutz C, Scriba TJ, Wilkinson KA, Wilkinson RJ, Boulware DR, Urban BC, Lalloo DG, Meintjes G.

J Infect Dis. 2016 Jun 1;213(11):1725-34. doi: 10.1093/infdis/jiw007. Epub 2016 Jan 14.

13.

Flow Cytometry To Assess Cerebrospinal Fluid Fungal Burden in Cryptococcal Meningitis.

Scriven JE, Graham LM, Schutz C, Scriba TJ, Wilkinson RJ, Boulware DR, Meintjes G, Lalloo DG, Urban BC.

J Clin Microbiol. 2016 Mar;54(3):802-4. doi: 10.1128/JCM.03002-15. Epub 2015 Dec 30.

14.

Altered Memory T-Cell Responses to Bacillus Calmette-Guerin and Tetanus Toxoid Vaccination and Altered Cytokine Responses to Polyclonal Stimulation in HIV-Exposed Uninfected Kenyan Infants.

Garcia-Knight MA, Nduati E, Hassan AS, Gambo F, Odera D, Etyang TJ, Hajj NJ, Berkley JA, Urban BC, Rowland-Jones SL.

PLoS One. 2015 Nov 16;10(11):e0143043. doi: 10.1371/journal.pone.0143043. eCollection 2015.

15.

Outcomes of prevention of mother to child transmission of the human immunodeficiency virus-1 in rural Kenya--a cohort study.

Nduati EW, Hassan AS, Knight MG, Muema DM, Jahangir MN, Mwaringa SL, Etyang TJ, Rowland-Jones S, Urban BC, Berkley JA.

BMC Public Health. 2015 Oct 3;15:1008. doi: 10.1186/s12889-015-2355-4.

16.

Control of Viremia Enables Acquisition of Resting Memory B Cells with Age and Normalization of Activated B Cell Phenotypes in HIV-Infected Children.

Muema DM, Macharia GN, Hassan AS, Mwaringa SM, Fegan GW, Berkley JA, Nduati EW, Urban BC.

J Immunol. 2015 Aug 1;195(3):1082-91. doi: 10.4049/jimmunol.1500491. Epub 2015 Jun 26.

17.

BCL-3 expression promotes colorectal tumorigenesis through activation of AKT signalling.

Urban BC, Collard TJ, Eagle CJ, Southern SL, Greenhough A, Hamdollah-Zadeh M, Ghosh A, Poulsom R, Paraskeva C, Silver A, Williams AC.

Gut. 2016 Jul;65(7):1151-64. doi: 10.1136/gutjnl-2014-308270. Epub 2015 Jun 1.

18.

Prime-boost vaccination with chimpanzee adenovirus and modified vaccinia Ankara encoding TRAP provides partial protection against Plasmodium falciparum infection in Kenyan adults.

Ogwang C, Kimani D, Edwards NJ, Roberts R, Mwacharo J, Bowyer G, Bliss C, Hodgson SH, Njuguna P, Viebig NK, Nicosia A, Gitau E, Douglas S, Illingworth J, Marsh K, Lawrie A, Imoukhuede EB, Ewer K, Urban BC, Hill AVS, Bejon P; MVVC group.

Sci Transl Med. 2015 May 6;7(286):286re5. doi: 10.1126/scitranslmed.aaa2373.

19.

10-valent pneumococcal non-typeable Haemophilus influenzae protein-D conjugate vaccine (PHiD-CV) induces memory B cell responses in healthy Kenyan toddlers.

Muema DM, Nduati EW, Uyoga M, Bashraheil M, Scott JA, Hammitt LL, Urban BC.

Clin Exp Immunol. 2015 Aug;181(2):297-305. doi: 10.1111/cei.12637. Epub 2015 Jun 10.

20.

Translating the immunogenicity of prime-boost immunization with ChAd63 and MVA ME-TRAP from malaria naive to malaria-endemic populations.

Kimani D, Jagne YJ, Cox M, Kimani E, Bliss CM, Gitau E, Ogwang C, Afolabi MO, Bowyer G, Collins KA, Edwards N, Hodgson SH, Duncan CJ, Spencer AJ, Knight MG, Drammeh A, Anagnostou NA, Berrie E, Moyle S, Gilbert SC, Soipei P, Okebe J, Colloca S, Cortese R, Viebig NK, Roberts R, Lawrie AM, Nicosia A, Imoukhuede EB, Bejon P, Chilengi R, Bojang K, Flanagan KL, Hill AV, Urban BC, Ewer KJ.

Mol Ther. 2014 Nov;22(11):1992-2003. doi: 10.1038/mt.2014.109. Epub 2014 Jun 16.

21.

CD4+ T cell responses to the Plasmodium falciparum erythrocyte membrane protein 1 in children with mild malaria.

Gitau EN, Tuju J, Karanja H, Stevenson L, Requena P, Kimani E, Olotu A, Kimani D, Marsh K, Bull P, Urban BC.

J Immunol. 2014 Feb 15;192(4):1753-61. doi: 10.4049/jimmunol.1200547. Epub 2014 Jan 22.

22.

HIV-exposed uninfected children: a growing population with a vulnerable immune system?

Afran L, Garcia Knight M, Nduati E, Urban BC, Heyderman RS, Rowland-Jones SL.

Clin Exp Immunol. 2014 Apr;176(1):11-22. doi: 10.1111/cei.12251. Review.

23.

Value of Plasmodium falciparum histidine-rich protein 2 level and malaria retinopathy in distinguishing cerebral malaria from other acute encephalopathies in Kenyan children.

Kariuki SM, Gitau E, Gwer S, Karanja HK, Chengo E, Kazungu M, Urban BC, Newton CR.

J Infect Dis. 2014 Feb 15;209(4):600-9. doi: 10.1093/infdis/jit500. Epub 2013 Sep 16.

24.

Inflammatory Flt3l is essential to mobilize dendritic cells and for T cell responses during Plasmodium infection.

Guermonprez P, Helft J, Claser C, Deroubaix S, Karanje H, Gazumyan A, Darasse-Jèze G, Telerman SB, Breton G, Schreiber HA, Frias-Staheli N, Billerbeck E, Dorner M, Rice CM, Ploss A, Klein F, Swiecki M, Colonna M, Kamphorst AO, Meredith M, Niec R, Takacs C, Mikhail F, Hari A, Bosque D, Eisenreich T, Merad M, Shi Y, Ginhoux F, Rénia L, Urban BC, Nussenzweig MC.

Nat Med. 2013 Jun;19(6):730-8. doi: 10.1038/nm.3197. Epub 2013 May 19.

25.

Safety and immunogenicity of heterologous prime-boost immunisation with Plasmodium falciparum malaria candidate vaccines, ChAd63 ME-TRAP and MVA ME-TRAP, in healthy Gambian and Kenyan adults.

Ogwang C, Afolabi M, Kimani D, Jagne YJ, Sheehy SH, Bliss CM, Duncan CJ, Collins KA, Garcia Knight MA, Kimani E, Anagnostou NA, Berrie E, Moyle S, Gilbert SC, Spencer AJ, Soipei P, Mueller J, Okebe J, Colloca S, Cortese R, Viebig NK, Roberts R, Gantlett K, Lawrie AM, Nicosia A, Imoukhuede EB, Bejon P, Urban BC, Flanagan KL, Ewer KJ, Chilengi R, Hill AV, Bojang K.

PLoS One. 2013;8(3):e57726. doi: 10.1371/journal.pone.0057726. Epub 2013 Mar 19.

26.

Endotoxaemia is common in children with Plasmodium falciparum malaria.

Olupot-Olupot P, Urban BC, Jemutai J, Nteziyaremye J, Fanjo HM, Karanja H, Karisa J, Ongodia P, Bwonyo P, Gitau EN, Talbert A, Akech S, Maitland K.

BMC Infect Dis. 2013 Mar 5;13:117. doi: 10.1186/1471-2334-13-117.

27.

The retinoblastoma protein (Rb) as an anti-apoptotic factor: expression of Rb is required for the anti-apoptotic function of BAG-1 protein in colorectal tumour cells.

Collard TJ, Urban BC, Patsos HA, Hague A, Townsend PA, Paraskeva C, Williams AC.

Cell Death Dis. 2012 Oct 11;3:e408. doi: 10.1038/cddis.2012.142.

28.

T-cell responses to the DBLα-tag, a short semi-conserved region of the Plasmodium falciparum membrane erythrocyte protein 1.

Gitau EN, Tuju J, Stevenson L, Kimani E, Karanja H, Marsh K, Bull PC, Urban BC.

PLoS One. 2012;7(1):e30095. doi: 10.1371/journal.pone.0030095. Epub 2012 Jan 17.

29.

Human complement Factor H modulates C1q-mediated phagocytosis of apoptotic cells.

Kang YH, Urban BC, Sim RB, Kishore U.

Immunobiology. 2012 Apr;217(4):455-64. doi: 10.1016/j.imbio.2011.10.008. Epub 2011 Oct 23.

PMID:
22088229
30.

BAG-1 interacts with the p50-p50 homodimeric NF-κB complex: implications for colorectal carcinogenesis.

Southern SL, Collard TJ, Urban BC, Skeen VR, Smartt HJ, Hague A, Oakley F, Townsend PA, Perkins ND, Paraskeva C, Williams AC.

Oncogene. 2012 May 31;31(22):2761-72. doi: 10.1038/onc.2011.452. Epub 2011 Oct 3.

31.

The plasma concentration of the B cell activating factor is increased in children with acute malaria.

Nduati E, Gwela A, Karanja H, Mugyenyi C, Langhorne J, Marsh K, Urban BC.

J Infect Dis. 2011 Sep 15;204(6):962-70. doi: 10.1093/infdis/jir438.

32.

Plasmodium falciparum-infected erythrocytes and beta-hematin induce partial maturation of human dendritic cells and increase their migratory ability in response to lymphoid chemokines.

Giusti P, Urban BC, Frascaroli G, Albrecht L, Tinti A, Troye-Blomberg M, Varani S.

Infect Immun. 2011 Jul;79(7):2727-36. doi: 10.1128/IAI.00649-10. Epub 2011 Apr 4.

33.

Specific receptor usage in Plasmodium falciparum cytoadherence is associated with disease outcome.

Ochola LB, Siddondo BR, Ocholla H, Nkya S, Kimani EN, Williams TN, Makale JO, Liljander A, Urban BC, Bull PC, Szestak T, Marsh K, Craig AG.

PLoS One. 2011 Mar 3;6(3):e14741. doi: 10.1371/journal.pone.0014741.

34.

Distinct kinetics of memory B-cell and plasma-cell responses in peripheral blood following a blood-stage Plasmodium chabaudi infection in mice.

Nduati EW, Ng DH, Ndungu FM, Gardner P, Urban BC, Langhorne J.

PLoS One. 2010 Nov 23;5(11):e15007. doi: 10.1371/journal.pone.0015007.

35.

Copy number, linkage disequilibrium and disease association in the FCGR locus.

Niederer HA, Willcocks LC, Rayner TF, Yang W, Lau YL, Williams TN, Scott JA, Urban BC, Peshu N, Dunstan SJ, Hien TT, Phu NH, Padyukov L, Gunnarsson I, Svenungsson E, Savage CO, Watts RA, Lyons PA, Clayton DG, Smith KG.

Hum Mol Genet. 2010 Aug 15;19(16):3282-94. doi: 10.1093/hmg/ddq216. Epub 2010 May 27.

36.

A defunctioning polymorphism in FCGR2B is associated with protection against malaria but susceptibility to systemic lupus erythematosus.

Willcocks LC, Carr EJ, Niederer HA, Rayner TF, Williams TN, Yang W, Scott JA, Urban BC, Peshu N, Vyse TJ, Lau YL, Lyons PA, Smith KG.

Proc Natl Acad Sci U S A. 2010 Apr 27;107(17):7881-5. doi: 10.1073/pnas.0915133107. Epub 2010 Apr 12.

37.

Immune recognition of Plasmodium-infected erythrocytes.

Cordery DV, Urban BC.

Adv Exp Med Biol. 2009;653:175-84. Review. No abstract available.

PMID:
19799119
38.

Multiple functions of human T cells generated by experimental malaria challenge.

Todryk SM, Walther M, Bejon P, Hutchings C, Thompson FM, Urban BC, Porter DW, Hill AV.

Eur J Immunol. 2009 Nov;39(11):3042-51. doi: 10.1002/eji.200939434. Erratum in: Eur J Immunol. 2011 Apr;41(4):1176.

39.

Dendritic cells in Plasmodium infection.

Todryk SM, Urban BC.

Future Microbiol. 2008 Jun;3(3):279-86. doi: 10.2217/17460913.3.3.279. Review.

PMID:
18505394
40.

Characterization of a Plasmodium falciparum macrophage-migration inhibitory factor homologue.

Cordery DV, Kishore U, Kyes S, Shafi MJ, Watkins KR, Williams TN, Marsh K, Urban BC.

J Infect Dis. 2007 Mar 15;195(6):905-12. Epub 2007 Feb 1.

41.

The frequency of BDCA3-positive dendritic cells is increased in the peripheral circulation of Kenyan children with severe malaria.

Urban BC, Cordery D, Shafi MJ, Bull PC, Newbold CI, Williams TN, Marsh K.

Infect Immun. 2006 Dec;74(12):6700-6. Epub 2006 Sep 25.

42.

The effect of Plasmodium falciparum infection on expression of monocyte surface molecules.

Jenkins NE, Chakravorty SJ, Urban BC, Kai OK, Marsh K, Craig AG.

Trans R Soc Trop Med Hyg. 2006 Nov;100(11):1007-12. Epub 2006 Jun 12.

PMID:
16765392
43.

Malaria pigment paralyzes dendritic cells.

Urban BC, Todryk S.

J Biol. 2006;5(2):4. Epub 2006 Apr 12. Review.

44.

Frequencies of peripheral blood myeloid cells in healthy Kenyan children with alpha+ thalassemia and the sickle cell trait.

Urban BC, Shafi MJ, Cordery DV, Macharia A, Lowe B, Marsh K, Williams TN.

Am J Trop Med Hyg. 2006 Apr;74(4):578-84.

45.

Antigen presentation and dendritic cell biology in malaria.

Stevenson MM, Urban BC.

Parasite Immunol. 2006 Jan-Feb;28(1-2):5-14. Review.

46.

Early interactions between blood-stage plasmodium parasites and the immune system.

Urban BC, Ing R, Stevenson MM.

Curr Top Microbiol Immunol. 2005;297:25-70. Review.

PMID:
16265902
47.

Regulation of immune response by Plasmodium-infected red blood cells.

Ndungu FM, Urban BC, Marsh K, Langhorne J.

Parasite Immunol. 2005 Oct-Nov;27(10-11):373-84. Review.

48.

PfEMP1 expression is reduced on the surface of knobless Plasmodium falciparum infected erythrocytes.

Horrocks P, Pinches RA, Chakravorty SJ, Papakrivos J, Christodoulou Z, Kyes SA, Urban BC, Ferguson DJ, Newbold CI.

J Cell Sci. 2005 Jun 1;118(Pt 11):2507-18.

49.

Immunological properties of human decidual macrophages--a possible role in intrauterine immunity.

Singh U, Nicholson G, Urban BC, Sargent IL, Kishore U, Bernal AL.

Reproduction. 2005 May;129(5):631-7.

PMID:
15855626
50.

Fatal Plasmodium falciparum malaria causes specific patterns of splenic architectural disorganization.

Urban BC, Hien TT, Day NP, Phu NH, Roberts R, Pongponratn E, Jones M, Mai NT, Bethell D, Turner GD, Ferguson D, White NJ, Roberts DJ.

Infect Immun. 2005 Apr;73(4):1986-94.

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