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Items: 25


Bexarotene - a novel modulator of AURKA and the primary cilium in VHL-deficient cells.

Chowdhury P, Powell RT, Stephan C, Uray IP, Talley T, Karki M, Tripathi DN, Park YS, Mancini MA, Davies P, Dere R.

J Cell Sci. 2018 Dec 14;131(24). pii: jcs219923. doi: 10.1242/jcs.219923.


Transglutaminase 2 programs differentiating acute promyelocytic leukemia cells in all-trans retinoic acid treatment to inflammatory stage through NF-kB activation.

Jambrovics K, Uray IP, Keressztesy Z, Keillor JW, Fésüs L, Balajthy Z.

Haematologica. 2018 Sep 20. pii: haematol.2018.192823. doi: 10.3324/haematol.2018.192823. [Epub ahead of print]


Natural product β-thujaplicin inhibits homologous recombination repair and sensitizes cancer cells to radiation therapy.

Zhang L, Peng Y, Uray IP, Shen J, Wang L, Peng X, Brown PH, Tu W, Peng G.

DNA Repair (Amst). 2017 Dec;60:89-101. doi: 10.1016/j.dnarep.2017.10.009. Epub 2017 Oct 24.


Identifying Cell Cycle Modulators That Selectively Target ARID1A Deficiency Using High-Throughput Image-Based Screening.

Zhang L, Shen J, Yin Y, Peng Y, Wang L, Hsieh HJ, Shen Q, Brown PH, Tao K, Uray IP, Peng G.

SLAS Discov. 2017 Aug;22(7):813-826. doi: 10.1177/2472555217698942. Epub 2017 Mar 15.


Retinoids and rexinoids in cancer prevention: from laboratory to clinic.

Uray IP, Dmitrovsky E, Brown PH.

Semin Oncol. 2016 Feb;43(1):49-64. doi: 10.1053/j.seminoncol.2015.09.002. Epub 2015 Sep 25. Review.


The SOX11 transcription factor is a critical regulator of basal-like breast cancer growth, invasion, and basal-like gene expression.

Shepherd JH, Uray IP, Mazumdar A, Tsimelzon A, Savage M, Hilsenbeck SG, Brown PH.

Oncotarget. 2016 Mar 15;7(11):13106-21. doi: 10.18632/oncotarget.7437.


ARID1A Deficiency Impairs the DNA Damage Checkpoint and Sensitizes Cells to PARP Inhibitors.

Shen J, Peng Y, Wei L, Zhang W, Yang L, Lan L, Kapoor P, Ju Z, Mo Q, Shih IeM, Uray IP, Wu X, Brown PH, Shen X, Mills GB, Peng G.

Cancer Discov. 2015 Jul;5(7):752-67. doi: 10.1158/2159-8290.CD-14-0849. Epub 2015 Jun 11.


Atypical antipsychotics induce both proinflammatory and adipogenic gene expression in human adipocytes in vitro.

Sárvári AK, Veréb Z, Uray IP, Fésüs L, Balajthy Z.

Biochem Biophys Res Commun. 2014 Aug 8;450(4):1383-9. doi: 10.1016/j.bbrc.2014.07.005. Epub 2014 Jul 11.


SLC22A5/OCTN2 expression in breast cancer is induced by estrogen via a novel intronic estrogen-response element (ERE).

Wang C, Uray IP, Mazumdar A, Mayer JA, Brown PH.

Breast Cancer Res Treat. 2012 Jul;134(1):101-15. doi: 10.1007/s10549-011-1925-0. Epub 2012 Jan 3.


Cancer-preventive rexinoid modulates neutral lipid contents of mammary epithelial cells through a peroxisome proliferator-activated receptor γ-dependent mechanism.

Uray IP, Rodenberg JM, Bissonnette RP, Brown PH, Mancini MA.

Mol Pharmacol. 2012 Feb;81(2):228-38. doi: 10.1124/mol.111.072967. Epub 2011 Nov 3.


Chemoprevention of hormone receptor-negative breast cancer: new approaches needed.

Uray IP, Brown PH.

Recent Results Cancer Res. 2011;188:147-62. doi: 10.1007/978-3-642-10858-7_13. Review.


Androgen receptor mutations associated with androgen insensitivity syndrome: a high content analysis approach leading to personalized medicine.

Szafran AT, Hartig S, Sun H, Uray IP, Szwarc M, Shen Y, Mediwala SN, Bell J, McPhaul MJ, Mancini MA, Marcelli M.

PLoS One. 2009 Dec 9;4(12):e8179. doi: 10.1371/journal.pone.0008179.


Targeting the activator protein 1 transcription factor for the prevention of estrogen receptor-negative mammary tumors.

Shen Q, Uray IP, Li Y, Zhang Y, Hill J, Xu XC, Young MR, Gunther EJ, Hilsenbeck SG, Colburn NH, Chodosh LA, Brown PH.

Cancer Prev Res (Phila). 2008 Jun;1(1):45-55. doi: 10.1158/1940-6207.CAPR-08-0034. Epub 2008 Mar 31.


Rexinoid-induced expression of IGFBP-6 requires RARbeta-dependent permissive cooperation of retinoid receptors and AP-1.

Uray IP, Shen Q, Seo HS, Kim H, Lamph WW, Bissonnette RP, Brown PH.

J Biol Chem. 2009 Jan 2;284(1):345-53. doi: 10.1074/jbc.M804721200. Epub 2008 Oct 28.


The AP-1 transcription factor regulates breast cancer cell growth via cyclins and E2F factors.

Shen Q, Uray IP, Li Y, Krisko TI, Strecker TE, Kim HT, Brown PH.

Oncogene. 2008 Jan 10;27(3):366-77. Epub 2007 Jul 16.


Prevention of breast cancer: current state of the science and future opportunities.

Uray IP, Brown PH.

Expert Opin Investig Drugs. 2006 Dec;15(12):1583-600. Review.


The AP-1 transcription factor regulates postnatal mammary gland development.

Shen Q, Zhang Y, Uray IP, Hill JL, Kim HT, Lu C, Young MR, Gunther EJ, Hilsenbeck SG, Chodosh LA, Colburn NH, Brown PH.

Dev Biol. 2006 Jul 15;295(2):589-603. Epub 2006 Apr 4.


Akt phosphorylates and suppresses the transactivation of retinoic acid receptor alpha.

Srinivas H, Xia D, Moore NL, Uray IP, Kim H, Ma L, Weigel NL, Brown PH, Kurie JM.

Biochem J. 2006 May 1;395(3):653-62.


Retinoid X receptors: X-ploring their (patho)physiological functions.

Szanto A, Narkar V, Shen Q, Uray IP, Davies PJ, Nagy L.

Cell Death Differ. 2004 Dec;11 Suppl 2:S126-43. Review.


Estradiol down-regulates CD36 expression in human breast cancer cells.

Uray IP, Liang Y, Hyder SM.

Cancer Lett. 2004 Apr 15;207(1):101-7.


Mechanical unloading increases caveolin expression in the failing human heart.

Uray IP, Connelly JH, Frazier OH, Taegtmeyer H, Davies PJ.

Cardiovasc Res. 2003 Jul 1;59(1):57-66.


Downregulation of metabolic gene expression in failing human heart before and after mechanical unloading.

Razeghi P, Young ME, Ying J, Depre C, Uray IP, Kolesar J, Shipley GL, Moravec CS, Davies PJ, Frazier OH, Taegtmeyer H.

Cardiology. 2002;97(4):203-9.


Left ventricular unloading alters receptor tyrosine kinase expression in the failing human heart.

Uray IP, Connelly JH, Thomázy V, Shipley GL, Vaughn WK, Frazier OH, Taegtmeyer H, Davies PJ.

J Heart Lung Transplant. 2002 Jul;21(7):771-82.


Altered expression of tyrosine kinase receptors Her2/neu and GP130 following left ventricular assist device (LVAD) placement in patients with heart failure.

Uray IP, Connelly JH, Frazier O, Taegtmeyer H, Davies PJ.

J Heart Lung Transplant. 2001 Feb;20(2):210. No abstract available.


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