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Items: 1 to 50 of 52

1.

Resistance to Second-Generation HIV-1 Maturation Inhibitors.

Urano E, Timilsina U, Kaplan JA, Ablan S, Ghimire D, Pham P, Kuruppu N, Mandt R, Durell SR, Nitz TJ, Martin DE, Wild CT, Gaur R, Freed EO.

J Virol. 2019 Mar 5;93(6). pii: e02017-18. doi: 10.1128/JVI.02017-18. Print 2019 Mar 15.

PMID:
30567982
2.

Quenching protein dynamics interferes with HIV capsid maturation.

Wang M, Quinn CM, Perilla JR, Zhang H, Shirra R Jr, Hou G, Byeon IJ, Suiter CL, Ablan S, Urano E, Nitz TJ, Aiken C, Freed EO, Zhang P, Schulten K, Gronenborn AM, Polenova T.

Nat Commun. 2017 Nov 24;8(1):1779. doi: 10.1038/s41467-017-01856-y.

3.

A Triazinone Derivative Inhibits HIV-1 Replication by Interfering with Reverse Transcriptase Activity.

Urano E, Miyauchi K, Kojima Y, Hamatake M, Ablan SD, Fudo S, Freed EO, Hoshino T, Komano J.

ChemMedChem. 2016 Oct 19;11(20):2320-2326. doi: 10.1002/cmdc.201600375. Epub 2016 Sep 16.

PMID:
27634404
4.

Conformational properties of the third variable loop of HIV-1AD8 envelope glycoprotein in the liganded conditions.

Takeda S, Takizawa M, Miyauchi K, Urano E, Fujino M, Murakami T, Murakami T, Komano J.

Biochem Biophys Res Commun. 2016 Jun 17;475(1):113-8. doi: 10.1016/j.bbrc.2016.05.051. Epub 2016 May 10.

PMID:
27178216
5.

Identification of an HIV-1 Mutation in Spacer Peptide 1 That Stabilizes the Immature CA-SP1 Lattice.

Fontana J, Keller PW, Urano E, Ablan SD, Steven AC, Freed EO.

J Virol. 2015 Nov 4;90(2):972-8. doi: 10.1128/JVI.02204-15. Print 2016 Jan 15.

6.

Alkyl Amine Bevirimat Derivatives Are Potent and Broadly Active HIV-1 Maturation Inhibitors.

Urano E, Ablan SD, Mandt R, Pauly GT, Sigano DM, Schneider JP, Martin DE, Nitz TJ, Wild CT, Freed EO.

Antimicrob Agents Chemother. 2015 Oct 19;60(1):190-7. doi: 10.1128/AAC.02121-15. Print 2016 Jan.

7.

Recovery of nutritional metabolism after liver transplantation.

Sugihara K, Yamanaka-Okumura H, Teramoto A, Urano E, Katayama T, Morine Y, Imura S, Utsunomiya T, Shimada M, Takeda E.

Nutrition. 2015 Jan;31(1):105-10. doi: 10.1016/j.nut.2014.05.016. Epub 2014 Jul 8.

PMID:
25441593
8.

Comparison of measured and predicted energy expenditure in patients with liver cirrhosis.

Teramoto A, Yamanaka-Okumura H, Urano E, Nakamura-Kutsuzawa T, Sugihara K, Katayama T, Miyake H, Imura S, Utsunomiya T, Shimada M, Takeda E.

Asia Pac J Clin Nutr. 2014;23(2):197-204. doi: 10.6133/apjcn.2014.23.2.12.

9.

Recovery pattern of non-protein respiratory quotient and non-esterified fatty acids after liver resection.

Sugihara K, Yamanaka-Okumura H, Teramoto A, Urano E, Katayama T, Mori H, Utsunomiya T, Shimada M, Takeda E.

Nutrition. 2014 Apr;30(4):443-8. doi: 10.1016/j.nut.2013.09.012. Epub 2013 Oct 3.

PMID:
24332605
10.

Pre- and postoperative nutritional assessment and health-related quality of life in recipients of living donor liver transplantation.

Urano E, Yamanaka-Okumura H, Teramoto A, Sugihara K, Morine Y, Imura S, Utsunomiya T, Shimada M, Takeda E.

Hepatol Res. 2014 Oct;44(11):1102-9. doi: 10.1111/hepr.12263. Epub 2013 Nov 26.

PMID:
24164744
11.

Novel role of HSP40/DNAJ in the regulation of HIV-1 replication.

Urano E, Morikawa Y, Komano J.

J Acquir Immune Defic Syndr. 2013 Oct 1;64(2):154-62. doi: 10.1097/QAI.0b013e31829a2ef8.

PMID:
24047968
12.

Cell-permeable stapled peptides based on HIV-1 integrase inhibitors derived from HIV-1 gene products.

Nomura W, Aikawa H, Ohashi N, Urano E, Métifiot M, Fujino M, Maddali K, Ozaki T, Nozue A, Narumi T, Hashimoto C, Tanaka T, Pommier Y, Yamamoto N, Komano JA, Murakami T, Tamamura H.

ACS Chem Biol. 2013 Oct 18;8(10):2235-44. doi: 10.1021/cb400495h. Epub 2013 Aug 15.

PMID:
23898787
13.

A novel therapeutic molecule against HTLV-1 infection targeting provirus.

Tanaka A, Takeda S, Kariya R, Matsuda K, Urano E, Okada S, Komano J.

Leukemia. 2013 Aug;27(8):1621-7. doi: 10.1038/leu.2013.46. Epub 2013 Feb 15.

PMID:
23411465
14.

Hypothermia-dependent and -independent effects of forced swim on the phosphorylation states of signaling molecules in mouse hippocampus.

Hayashi Y, Kusakari S, Sato-Hashimoto M, Urano E, Shigeno M, Sekijima T, Kotani T, Murata Y, Murakami H, Matozaki T, Ohnishi H.

Biochem Biophys Res Commun. 2012 Nov 30;428(4):475-81. doi: 10.1016/j.bbrc.2012.10.083. Epub 2012 Oct 30.

PMID:
23122813
15.

Toll-like receptor (TLR) 3 as a surrogate sensor of retroviral infection in human cells.

Miyauchi K, Urano E, Takeda S, Murakami T, Okada Y, Cheng K, Yin H, Kubo M, Komano J.

Biochem Biophys Res Commun. 2012 Aug 3;424(3):519-23. doi: 10.1016/j.bbrc.2012.06.148. Epub 2012 Jul 4.

PMID:
22771581
16.

Regulation of cyclin T1 expression and function by an alternative splice variant that skips exon 7 and contains a premature termination codon.

Urano E, Miyauchi K, Ichikawa R, Futahashi Y, Komano J.

Gene. 2012 Aug 15;505(1):1-8. doi: 10.1016/j.gene.2012.06.006. Epub 2012 Jun 9.

PMID:
22692005
17.

Structural modulation study of inhibitory compounds for ribonuclease H activity of human immunodeficiency virus type 1 reverse transcriptase.

Yanagita H, Fudo S, Urano E, Ichikawa R, Ogata M, Yokota M, Murakami T, Wu H, Chiba J, Komano J, Hoshino T.

Chem Pharm Bull (Tokyo). 2012;60(6):764-71.

18.

Evaluation of a synthetic C34 trimer of HIV-1 gp41 as AIDS vaccines.

Hashimoto C, Nomura W, Ohya A, Urano E, Miyauchi K, Narumi T, Aikawa H, Komano JA, Yamamoto N, Tamamura H.

Bioorg Med Chem. 2012 May 15;20(10):3287-91. doi: 10.1016/j.bmc.2012.03.050. Epub 2012 Mar 29.

PMID:
22507207
19.

Therapeutic potential of HIV protease-activable CASP3.

Miyauchi K, Urano E, Takizawa M, Ichikawa R, Komano J.

Sci Rep. 2012;2:359. doi: 10.1038/srep00359. Epub 2012 Apr 11.

20.

Treatment of rapid weight loss in a donor with hepatic steatosis in living donor liver transplantation: a case report.

Yamanaka-Okumura H, Urano E, Kawaura A, Imura S, Utsunomiya T, Shimada M, Takeda E.

Hepatogastroenterology. 2012 May;59(115):869-71. doi: 10.5754/hge10237.

PMID:
22469734
21.

A synthetic C34 trimer of HIV-1 gp41 shows significant increase in inhibition potency.

Nomura W, Hashimoto C, Ohya A, Miyauchi K, Urano E, Tanaka T, Narumi T, Nakahara T, Komano JA, Yamamoto N, Tamamura H.

ChemMedChem. 2012 Feb 6;7(2):205-8. doi: 10.1002/cmdc.201100542. Epub 2012 Jan 13. No abstract available. Erratum in: ChemMedChem. 2012 Apr;7(4):546.

PMID:
22247043
22.

The hematopoietic cell-specific Rho GTPase inhibitor ARHGDIB/D4GDI limits HIV type 1 replication.

Watanabe T, Urano E, Miyauchi K, Ichikawa R, Hamatake M, Misawa N, Sato K, Ebina H, Koyanagi Y, Komano J.

AIDS Res Hum Retroviruses. 2012 Aug;28(8):913-22. doi: 10.1089/AID.2011.0180. Epub 2011 Nov 22.

PMID:
21936715
23.

Regulation of the susceptibility of HIV-1 to a neutralizing antibody KD-247 by nonepitope mutations distant from its epitope.

Takizawa M, Miyauchi K, Urano E, Kusagawa S, Kitamura K, Naganawa S, Murakami T, Honda M, Yamamoto N, Komano J.

AIDS. 2011 Nov 28;25(18):2209-16. doi: 10.1097/QAD.0b013e32834bab68.

PMID:
21866041
24.

Novel postentry inhibitor of human immunodeficiency virus type 1 replication screened by yeast membrane-associated two-hybrid system.

Urano E, Kuramochi N, Ichikawa R, Murayama SY, Miyauchi K, Tomoda H, Takebe Y, Nermut M, Komano J, Morikawa Y.

Antimicrob Agents Chemother. 2011 Sep;55(9):4251-60. doi: 10.1128/AAC.00299-11. Epub 2011 Jul 11.

25.

Protein transduction by pseudotyped lentivirus-like nanoparticles.

Aoki T, Miyauchi K, Urano E, Ichikawa R, Komano J.

Gene Ther. 2011 Sep;18(9):936-41. doi: 10.1038/gt.2011.38. Epub 2011 Mar 31.

PMID:
21451580
26.

Cytokine signatures of transformed B cells with distinct Epstein-Barr virus latencies as a potential diagnostic tool for B cell lymphoma.

Miyauchi K, Urano E, Yoshiyama H, Komano J.

Cancer Sci. 2011 Jun;102(6):1236-41. doi: 10.1111/j.1349-7006.2011.01924.x. Epub 2011 Apr 1.

27.

Structural and biochemical study on the inhibitory activity of derivatives of 5-nitro-furan-2-carboxylic acid for RNase H function of HIV-1 reverse transcriptase.

Yanagita H, Urano E, Matsumoto K, Ichikawa R, Takaesu Y, Ogata M, Murakami T, Wu H, Chiba J, Komano J, Hoshino T.

Bioorg Med Chem. 2011 Jan 15;19(2):816-25. doi: 10.1016/j.bmc.2010.12.011. Epub 2010 Dec 9.

PMID:
21193314
28.

Peptidic HIV integrase inhibitors derived from HIV gene products: structure-activity relationship studies.

Suzuki S, Maddali K, Hashimoto C, Urano E, Ohashi N, Tanaka T, Ozaki T, Arai H, Tsutsumi H, Narumi T, Nomura W, Yamamoto N, Pommier Y, Komano JA, Tamamura H.

Bioorg Med Chem. 2010 Sep 15;18(18):6771-5. doi: 10.1016/j.bmc.2010.07.050. Epub 2010 Jul 25.

29.

Peptide HIV-1 integrase inhibitors from HIV-1 gene products.

Suzuki S, Urano E, Hashimoto C, Tsutsumi H, Nakahara T, Tanaka T, Nakanishi Y, Maddali K, Han Y, Hamatake M, Miyauchi K, Pommier Y, Beutler JA, Sugiura W, Fuji H, Hoshino T, Itotani K, Nomura W, Narumi T, Yamamoto N, Komano JA, Tamamura H.

J Med Chem. 2010 Jul 22;53(14):5356-60. doi: 10.1021/jm1003528.

30.

T cell-based functional cDNA library screening identified SEC14-like 1a carboxy-terminal domain as a negative regulator of human immunodeficiency virus replication.

Urano E, Ichikawa R, Morikawa Y, Yoshida T, Koyanagi Y, Komano J.

Vaccine. 2010 May 26;28 Suppl 2:B68-74. doi: 10.1016/j.vaccine.2009.07.084.

PMID:
20510747
31.

Improvement of lentiviral vector-mediated gene transduction by genetic engineering of the structural protein Pr55 Gag.

Aoki T, Shimizu S, Urano E, Futahashi Y, Hamatake M, Tamamura H, Terashima K, Murakami T, Yamamoto N, Komano J.

Gene Ther. 2010 Sep;17(9):1124-33. doi: 10.1038/gt.2010.61. Epub 2010 Apr 22.

PMID:
20410927
32.

Inhibition of HIV replication by a CD4-reactive Fab of an IgM clone isolated from a healthy HIV-seronegative individual.

Hamatake M, Komano J, Urano E, Maeda F, Nagatsuka Y, Takekoshi M.

Eur J Immunol. 2010 May;40(5):1504-9. doi: 10.1002/eji.200939479.

33.

Dominant-negative derivative of EBNA1 represses EBNA1-mediated transforming gene expression during the acute phase of Epstein-Barr virus infection independent of rapid loss of viral genome.

Kariya Y, Hamatake M, Urano E, Yoshiyama H, Shimizu N, Komano J.

Cancer Sci. 2010 Apr;101(4):876-81. doi: 10.1111/j.1349-7006.2009.01474.x. Epub 2009 Dec 16.

34.

Derivatives of 5-nitro-furan-2-carboxylic acid carbamoylmethyl ester inhibit RNase H activity associated with HIV-1 reverse transcriptase.

Fuji H, Urano E, Futahashi Y, Hamatake M, Tatsumi J, Hoshino T, Morikawa Y, Yamamoto N, Komano J.

J Med Chem. 2009 Mar 12;52(5):1380-7. doi: 10.1021/jm801071m.

PMID:
19178289
35.

Ligand-independent higher-order multimerization of CXCR4, a G-protein-coupled chemokine receptor involved in targeted metastasis.

Hamatake M, Aoki T, Futahashi Y, Urano E, Yamamoto N, Komano J.

Cancer Sci. 2009 Jan;100(1):95-102. doi: 10.1111/j.1349-7006.2008.00997.x. Epub 2008 Oct 30.

36.

Substitution of the myristoylation signal of human immunodeficiency virus type 1 Pr55Gag with the phospholipase C-delta1 pleckstrin homology domain results in infectious pseudovirion production.

Urano E, Aoki T, Futahashi Y, Murakami T, Morikawa Y, Yamamoto N, Komano J.

J Gen Virol. 2008 Dec;89(Pt 12):3144-9. doi: 10.1099/vir.0.2008/004820-0.

37.

Identification of the P-TEFb complex-interacting domain of Brd4 as an inhibitor of HIV-1 replication by functional cDNA library screening in MT-4 cells.

Urano E, Kariya Y, Futahashi Y, Ichikawa R, Hamatake M, Fukazawa H, Morikawa Y, Yoshida T, Koyanagi Y, Yamamoto N, Komano J.

FEBS Lett. 2008 Dec 10;582(29):4053-8. doi: 10.1016/j.febslet.2008.10.047. Epub 2008 Nov 7.

38.

Cyclin K/CPR4 inhibits primate lentiviral replication by inactivating Tat/positive transcription elongation factor b-dependent long terminal repeat transcription.

Urano E, Shimizu S, Futahashi Y, Hamatake M, Morikawa Y, Takahashi N, Fukazawa H, Yamamoto N, Komano J.

AIDS. 2008 May 31;22(9):1081-3. doi: 10.1097/QAD.0b013e3282fc7319.

PMID:
18520353
39.

Inhibiting lentiviral replication by HEXIM1, a cellular negative regulator of the CDK9/cyclin T complex.

Shimizu S, Urano E, Futahashi Y, Miyauchi K, Isogai M, Matsuda Z, Nohtomi K, Onogi T, Takebe Y, Yamamoto N, Komano J.

AIDS. 2007 Mar 12;21(5):575-82.

PMID:
17314519
40.

Separate elements are required for ligand-dependent and -independent internalization of metastatic potentiator CXCR4.

Futahashi Y, Komano J, Urano E, Aoki T, Hamatake M, Miyauchi K, Yoshida T, Koyanagi Y, Matsuda Z, Yamamoto N.

Cancer Sci. 2007 Mar;98(3):373-9.

41.

Rapid propagation of low-fitness drug-resistant mutants of human immunodeficiency virus type 1 by a streptococcal metabolite sparsomycin.

Miyauchi K, Komano J, Myint L, Futahashi Y, Urano E, Matsuda Z, Chiba T, Miura H, Sugiura W, Yamamoto N.

Antivir Chem Chemother. 2006;17(4):167-74.

PMID:
17066895
42.

The interaction of HIV-1 with the host factors.

Komano J, Futahashi Y, Urano E, Miyauchi K, Murakami T, Matsuda Z, Yamamoto N.

Jpn J Infect Dis. 2005 Jun;58(3):125-30. Review.

43.

Gene expression of lipid binding protein transferred the ability of specific attachment of hemopoietic cells to non-supportive stromal cell line, MS-K.

Takashita E, Sugimoto K, Jiang H, Tohma M, Urano E, Yokoyama H, Mori KJ.

Cell Struct Funct. 1997 Dec;22(6):595-602.

44.

Leiomyoma of the bladder causing bilateral hydronephrosis: a case report.

Nakata S, Kurokawa K, Ebihara K, Urano E, Yamanaka H, Suzuki K.

Hinyokika Kiyo. 1990 Jun;36(6):707-10.

45.
46.

[Male sterility].

Urano E.

Horumon To Rinsho. 1974 Jan;22(1):176-7. Japanese. No abstract available.

PMID:
4857386
47.

[Re-evaluation of anti-androgen therapy in prostatic cancer].

Shida K, Shimazaki J, Urano E, Shinozaki R, Kurihara K.

Horumon To Rinsho. 1973 Apr;21(4):391-400. Japanese. No abstract available.

PMID:
4738797
48.

[Action mechanism of androgen on the prostate].

Shida K, Shimazaki J, Urano E, Kurihara H, Takahashi H.

Horumon To Rinsho. 1972 Dec;20(12):1063-79. Review. Japanese. No abstract available.

PMID:
4348517
49.

[Studies of mechanisms of the action of androgens on prostate. 3. Anti-androgenic effect of gestagenic compounds and treatment of benign prostatic hypertrophy with chlormadinone acetate].

Shida K, Shimazaki J, Urano E, Kurihara H, Takahashi H.

Nihon Hinyokika Gakkai Zasshi. 1972 Feb;63(2):109-28. Japanese. No abstract available.

PMID:
4113183
50.

[Studies on mechanisms of the action of androgens on prostate. 2. Inhibitory effect of estrogen on 5 -reductase and application of estradiol-17 diphosphate to treatment of prostatic cancer].

Shida K, Shimazaki J, Urano E, Kurihara H, Takahashi H.

Nihon Hinyokika Gakkai Zasshi. 1972 Jan;63(1):27-42. Japanese. No abstract available.

PMID:
5062566

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