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Items: 15


Aminoflavone, a ligand of the aryl hydrocarbon receptor, inhibits HIF-1alpha expression in an AhR-independent fashion.

Terzuoli E, Puppo M, Rapisarda A, Uranchimeg B, Cao L, Burger AM, Ziche M, Melillo G.

Cancer Res. 2010 Sep 1;70(17):6837-48. doi: 10.1158/0008-5472.CAN-10-1075. Epub 2010 Aug 24.


Mongolian and Japanese Joint Conference on "Echinococcosis: diagnosis, treatment and prevention in Mongolia" June 4, 2009.

Gurbadam A, Nyamkhuu D, Nyamkhuu G, Tsendjav A, Sergelen O, Narantuya B, Batsukh Z, Battsetseg G, Oyun-Erdene B, Uranchimeg B, Otgonbaatar D, Temuulen D, Bayarmaa E, Abmed D, Tsogtsaikhan S, Usukhbayar A, Smirmaul K, Gereltuya J, Ito A.

Parasit Vectors. 2010 Feb 8;3(1):8. doi: 10.1186/1756-3305-3-8.


Increased antitumor activity of bevacizumab in combination with hypoxia inducible factor-1 inhibition.

Rapisarda A, Hollingshead M, Uranchimeg B, Bonomi CA, Borgel SD, Carter JP, Gehrs B, Raffeld M, Kinders RJ, Parchment R, Anver MR, Shoemaker RH, Melillo G.

Mol Cancer Ther. 2009 Jul;8(7):1867-77. doi: 10.1158/1535-7163.MCT-09-0274. Epub 2009 Jul 7.


Cytotoxic and HIF-1alpha inhibitory compounds from Crossosoma bigelovii.

Klausmeyer P, Zhou Q, Scudiero DA, Uranchimeg B, Melillo G, Cardellina JH, Shoemaker RH, Chang CJ, McCloud TG.

J Nat Prod. 2009 May 22;72(5):805-12. doi: 10.1021/np8006342.


Endothelial monocyte activating polypeptide-II modulates endothelial cell responses by degrading hypoxia-inducible factor-1alpha through interaction with PSMA7, a component of the proteasome.

Tandle AT, Calvani M, Uranchimeg B, Zahavi D, Melillo G, Libutti SK.

Exp Cell Res. 2009 Jul 1;315(11):1850-9. doi: 10.1016/j.yexcr.2009.03.021. Epub 2009 Apr 10.


Induction of apoptosis in human cancer cells by candidaspongiolide, a novel sponge polyketide.

Trisciuoglio D, Uranchimeg B, Cardellina JH, Meragelman TL, Matsunaga S, Fusetani N, Del Bufalo D, Shoemaker RH, Melillo G.

J Natl Cancer Inst. 2008 Sep 3;100(17):1233-46. doi: 10.1093/jnci/djn239. Epub 2008 Aug 26.


Separation and SAR study of HIF-1alpha inhibitory tubulosines from Alangium cf. longiflorum.

Klausmeyer P, McCloud TG, Uranchimeg B, Melillo G, Scudiero DA, Cardellina JH 2nd, Shoemaker RH.

Planta Med. 2008 Feb;74(3):258-63. doi: 10.1055/s-2008-1034315. Epub 2008 Feb 26.


Interleukin 10 and TNFalpha synergistically enhance the expression of the G protein-coupled formylpeptide receptor 2 in microglia.

Iribarren P, Chen K, Gong W, Cho EH, Lockett S, Uranchimeg B, Wang JM.

Neurobiol Dis. 2007 Jul;27(1):90-8. Epub 2007 May 5.


Cell type-specific, topoisomerase II-dependent inhibition of hypoxia-inducible factor-1alpha protein accumulation by NSC 644221.

Creighton-Gutteridge M, Cardellina JH 2nd, Stephen AG, Rapisarda A, Uranchimeg B, Hite K, Denny WA, Shoemaker RH, Melillo G.

Clin Cancer Res. 2007 Feb 1;13(3):1010-8.


Hypoxic induction of an HIF-1alpha-dependent bFGF autocrine loop drives angiogenesis in human endothelial cells.

Calvani M, Rapisarda A, Uranchimeg B, Shoemaker RH, Melillo G.

Blood. 2006 Apr 1;107(7):2705-12. Epub 2005 Nov 22.


CpG-containing oligodeoxynucleotide promotes microglial cell uptake of amyloid beta 1-42 peptide by up-regulating the expression of the G-protein- coupled receptor mFPR2.

Iribarren P, Chen K, Hu J, Gong W, Cho EH, Lockett S, Uranchimeg B, Wang JM.

FASEB J. 2005 Dec;19(14):2032-4. Epub 2005 Oct 11.


Schedule-dependent inhibition of hypoxia-inducible factor-1alpha protein accumulation, angiogenesis, and tumor growth by topotecan in U251-HRE glioblastoma xenografts.

Rapisarda A, Zalek J, Hollingshead M, Braunschweig T, Uranchimeg B, Bonomi CA, Borgel SD, Carter JP, Hewitt SM, Shoemaker RH, Melillo G.

Cancer Res. 2004 Oct 1;64(19):6845-8.


Topoisomerase I-mediated inhibition of hypoxia-inducible factor 1: mechanism and therapeutic implications.

Rapisarda A, Uranchimeg B, Sordet O, Pommier Y, Shoemaker RH, Melillo G.

Cancer Res. 2004 Feb 15;64(4):1475-82.


Regulation of the chemokine receptor CXCR4 by hypoxia.

Schioppa T, Uranchimeg B, Saccani A, Biswas SK, Doni A, Rapisarda A, Bernasconi S, Saccani S, Nebuloni M, Vago L, Mantovani A, Melillo G, Sica A.

J Exp Med. 2003 Nov 3;198(9):1391-402.


Identification of small molecule inhibitors of hypoxia-inducible factor 1 transcriptional activation pathway.

Rapisarda A, Uranchimeg B, Scudiero DA, Selby M, Sausville EA, Shoemaker RH, Melillo G.

Cancer Res. 2002 Aug 1;62(15):4316-24.

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