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Items: 1 to 50 of 74

1.

Galectin-1-driven T cell exclusion in the tumor endothelium promotes immunotherapy resistance.

Nambiar DK, Aguilera T, Cao H, Kwok S, Kong C, Bloomstein J, Wang Z, Rangan VS, Jiang D, von Eyben R, Liang R, Agarwal S, Colevas AD, Korman A, Allen CT, Uppaluri R, Koong AC, Giaccia A, Le QT.

J Clin Invest. 2019 Nov 11. pii: 129025. doi: 10.1172/JCI129025. [Epub ahead of print]

2.

Neoadjuvant PD-1 immune checkpoint blockade reverses functional immunodominance among tumor-antigen specific T cells.

Friedman J, Moore EC, Zolkind P, Robbins Y, Clavijo PE, Sun L, Greene S, Morisada MV, Mydlarz WK, Schmitt N, Hodge JW, Schreiber H, Van Waes C, Uppaluri R, Allen C.

Clin Cancer Res. 2019 Oct 23. pii: clincanres.2209.2019. doi: 10.1158/1078-0432.CCR-19-2209. [Epub ahead of print]

PMID:
31645352
3.

Open-Sourced CIViC Annotation Pipeline to Identify and Annotate Clinically Relevant Variants Using Single-Molecule Molecular Inversion Probes.

Barnell EK, Waalkes A, Mosior MC, Penewit K, Cotto KC, Danos AM, Sheta LM, Campbell KM, Krysiak K, Rieke D, Spies NC, Skidmore ZL, Pritchard CC, Fehniger TA, Uppaluri R, Govindan R, Griffith M, Salipante SJ, Griffith OL.

JCO Clin Cancer Inform. 2019 Oct;3:1-12. doi: 10.1200/CCI.19.00077.

4.

Targeting EZH2 Enhances Antigen Presentation, Antitumor Immunity, and Circumvents Anti-PD-1 Resistance in Head and Neck Cancer.

Zhou L, Mudianto T, Ma X, Riley R, Uppaluri R.

Clin Cancer Res. 2019 Sep 27. doi: 10.1158/1078-0432.CCR-19-1351. [Epub ahead of print]

PMID:
31562203
5.

Disparities in Oral Cancer Screening Among Dental Professionals: NHANES 2011-2016.

Gupta A, Sonis S, Uppaluri R, Bergmark RW, Villa A.

Am J Prev Med. 2019 Oct;57(4):447-457. doi: 10.1016/j.amepre.2019.04.026. Epub 2019 Aug 20.

PMID:
31443957
6.

Combinatorial optimality of functional groups, process parameters, and Pd(II) adsorption-desorption characteristics for commercial anion exchange resins-synthetic electroless plating systems.

Nagireddi S, Golder AK, Uppaluri R.

Environ Sci Pollut Res Int. 2019 Jul 22. doi: 10.1007/s11356-019-05941-1. [Epub ahead of print]

PMID:
31332679
7.

The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of squamous cell carcinoma of the head and neck (HNSCC).

Cohen EEW, Bell RB, Bifulco CB, Burtness B, Gillison ML, Harrington KJ, Le QT, Lee NY, Leidner R, Lewis RL, Licitra L, Mehanna H, Mell LK, Raben A, Sikora AG, Uppaluri R, Whitworth F, Zandberg DP, Ferris RL.

J Immunother Cancer. 2019 Jul 15;7(1):184. doi: 10.1186/s40425-019-0662-5.

8.

Feasibility of poly-vinyl alcohol/starch/glycerol/citric acid composite films for wound dressing applications.

Das A, Uppaluri R, Das C.

Int J Biol Macromol. 2019 Jun 15;131:998-1007. doi: 10.1016/j.ijbiomac.2019.03.160. Epub 2019 Mar 23.

PMID:
30914366
9.

Role of EDTA on the Pd(II) adsorption characteristics of chitosan cross-linked 3-amino-1,2,4-triazole-5-thiol derivative from synthetic electroless plating solutions.

Nagireddi S, Golder AK, Uppaluri R.

Int J Biol Macromol. 2019 Apr 15;127:320-329. doi: 10.1016/j.ijbiomac.2019.01.033. Epub 2019 Jan 9.

PMID:
30639595
10.

Accounting for proximal variants improves neoantigen prediction.

Hundal J, Kiwala S, Feng YY, Liu CJ, Govindan R, Chapman WC, Uppaluri R, Swamidass SJ, Griffith OL, Mardis ER, Griffith M.

Nat Genet. 2019 Jan;51(1):175-179. doi: 10.1038/s41588-018-0283-9. Epub 2018 Dec 3.

11.

A deep learning approach to automate refinement of somatic variant calling from cancer sequencing data.

Ainscough BJ, Barnell EK, Ronning P, Campbell KM, Wagner AH, Fehniger TA, Dunn GP, Uppaluri R, Govindan R, Rohan TE, Griffith M, Mardis ER, Swamidass SJ, Griffith OL.

Nat Genet. 2018 Dec;50(12):1735-1743. doi: 10.1038/s41588-018-0257-y. Epub 2018 Nov 5.

12.

Radiologic predictors of immune checkpoint inhibitor response in advanced head and neck squamous cell carcinoma.

Sridharan V, Rahman RM, Huang RY, Chau NG, Lorch JH, Uppaluri R, Haddad RI, Hanna GJ, Schoenfeld JD.

Oral Oncol. 2018 Oct;85:29-34. doi: 10.1016/j.oraloncology.2018.08.005. Epub 2018 Aug 17.

PMID:
30220316
13.

Improved outcomes in PI3K-pathway-altered metastatic HPV oropharyngeal cancer.

Hanna GJ, Kacew A, Chau NG, Shivdasani P, Lorch JH, Uppaluri R, Haddad RI, MacConaill LE.

JCI Insight. 2018 Sep 6;3(17). pii: 122799. doi: 10.1172/jci.insight.122799. eCollection 2018 Sep 6.

14.

Oral Cavity Squamous Cell Carcinoma Xenografts Retain Complex Genotypes and Intertumor Molecular Heterogeneity.

Campbell KM, Lin T, Zolkind P, Barnell EK, Skidmore ZL, Winkler AE, Law JH, Mardis ER, Wartman LD, Adkins DR, Chernock RD, Griffith M, Uppaluri R, Griffith OL.

Cell Rep. 2018 Aug 21;24(8):2167-2178. doi: 10.1016/j.celrep.2018.07.058.

15.

Tumor innate immunity primed by specific interferon-stimulated endogenous retroviruses.

Cañadas I, Thummalapalli R, Kim JW, Kitajima S, Jenkins RW, Christensen CL, Campisi M, Kuang Y, Zhang Y, Gjini E, Zhang G, Tian T, Sen DR, Miao D, Imamura Y, Thai T, Piel B, Terai H, Aref AR, Hagan T, Koyama S, Watanabe M, Baba H, Adeni AE, Lydon CA, Tamayo P, Wei Z, Herlyn M, Barbie TU, Uppaluri R, Sholl LM, Sicinska E, Sands J, Rodig S, Wong KK, Paweletz CP, Watanabe H, Barbie DA.

Nat Med. 2018 Aug;24(8):1143-1150. doi: 10.1038/s41591-018-0116-5. Epub 2018 Jul 23.

16.

Evaluating the PD-1 Axis and Immune Effector Cell Infiltration in Oropharyngeal Squamous Cell Carcinoma.

Schoenfeld JD, Gjini E, Rodig SJ, Tishler RB, Rawal B, Catalano PJ, Uppaluri R, Haddad RI, Hanna GJ, Chau NG, Rabinowits G, Lorch J, Jo VY, Krane JF, Goguen LA, Annino DJ, Abdelrahman S, Lipschitz M, Margalit DN.

Int J Radiat Oncol Biol Phys. 2018 Sep 1;102(1):137-145. doi: 10.1016/j.ijrobp.2018.05.002. Epub 2018 Jun 29.

PMID:
29960819
17.

Integrated genomic characterization of oral carcinomas in post-hematopoietic stem cell transplantation survivors.

Hanna GJ, Kofman ER, Shazib MA, Woo SB, Reardon B, Treister NS, Haddad RI, Cutler CS, Antin JH, Van Allen EM, Uppaluri R, Soiffer RJ.

Oral Oncol. 2018 Jun;81:1-9. doi: 10.1016/j.oraloncology.2018.04.007. Epub 2018 Apr 10.

PMID:
29884406
18.

Frameshift events predict anti-PD-1/L1 response in head and neck cancer.

Hanna GJ, Lizotte P, Cavanaugh M, Kuo FC, Shivdasani P, Frieden A, Chau NG, Schoenfeld JD, Lorch JH, Uppaluri R, MacConaill LE, Haddad RI.

JCI Insight. 2018 Feb 22;3(4). pii: 98811. doi: 10.1172/jci.insight.98811. eCollection 2018 Feb 22.

19.

Cancer immunogenomic approach to neoantigen discovery in a checkpoint blockade responsive murine model of oral cavity squamous cell carcinoma.

Zolkind P, Przybylski D, Marjanovic N, Nguyen L, Lin T, Johanns T, Alexandrov A, Zhou L, Allen CT, Miceli AP, Schreiber RD, Artyomov M, Dunn GP, Uppaluri R.

Oncotarget. 2017 Dec 28;9(3):4109-4119. doi: 10.18632/oncotarget.23751. eCollection 2018 Jan 9.

20.

Anti-Trop2 blockade enhances the therapeutic efficacy of ErbB3 inhibition in head and neck squamous cell carcinoma.

Redlich N, Robinson AM, Nickel KP, Stein AP, Wheeler DL, Adkins DR, Uppaluri R, Kimple RJ, Van Tine BA, Michel LS.

Cell Death Dis. 2018 Jan 5;9(1):5. doi: 10.1038/s41419-017-0029-0.

21.

CD271 Confers an Invasive and Metastatic Phenotype of Head and Neck Squamous Cell Carcinoma through the Upregulation of Slug.

Chung MK, Jung YH, Lee JK, Cho SY, Murillo-Sauca O, Uppaluri R, Shin JH, Sunwoo JB.

Clin Cancer Res. 2018 Feb 1;24(3):674-683. doi: 10.1158/1078-0432.CCR-17-0866. Epub 2017 Dec 5.

22.

Rationale for neoadjuvant immunotherapy in head and neck squamous cell carcinoma.

Hanna GJ, Adkins DR, Zolkind P, Uppaluri R.

Oral Oncol. 2017 Oct;73:65-69. doi: 10.1016/j.oraloncology.2017.08.008. Epub 2017 Aug 17. Review.

PMID:
28939078
23.

Checkpoint immunotherapy in head and neck cancers.

Zolkind P, Uppaluri R.

Cancer Metastasis Rev. 2017 Sep;36(3):475-489. doi: 10.1007/s10555-017-9694-9. Review.

PMID:
28836124
24.

Defining an inflamed tumor immunophenotype in recurrent, metastatic squamous cell carcinoma of the head and neck.

Hanna GJ, Liu H, Jones RE, Bacay AF, Lizotte PH, Ivanova EV, Bittinger MA, Cavanaugh ME, Rode AJ, Schoenfeld JD, Chau NG, Haddad RI, Lorch JH, Wong KK, Uppaluri R, Hammerman PS.

Oral Oncol. 2017 Apr;67:61-69. doi: 10.1016/j.oraloncology.2017.02.005. Epub 2017 Feb 14.

PMID:
28351582
25.

Biomarker and Tumor Responses of Oral Cavity Squamous Cell Carcinoma to Trametinib: A Phase II Neoadjuvant Window-of-Opportunity Clinical Trial.

Uppaluri R, Winkler AE, Lin T, Law JH, Haughey BH, Nussenbaum B, Paniello RC, Rich JT, Diaz JA, Michel LP, Wildes T, Dunn GP, Zolkind P, Kallogjeri D, Piccirillo JF, Dehdashti F, Siegel BA, Chernock RD, Lewis JS Jr, Adkins DR.

Clin Cancer Res. 2017 May 1;23(9):2186-2194. doi: 10.1158/1078-0432.CCR-16-1469. Epub 2016 Nov 9.

26.

Retropharyngeal Mass.

Graboyes EM, Aranake-Chrisinger J, Uppaluri R.

JAMA Otolaryngol Head Neck Surg. 2017 Apr 1;143(4):421-422. doi: 10.1001/jamaoto.2016.3008. No abstract available.

PMID:
27978561
27.

Immunogenomics of Hypermutated Glioblastoma: A Patient with Germline POLE Deficiency Treated with Checkpoint Blockade Immunotherapy.

Johanns TM, Miller CA, Dorward IG, Tsien C, Chang E, Perry A, Uppaluri R, Ferguson C, Schmidt RE, Dahiya S, Ansstas G, Mardis ER, Dunn GP.

Cancer Discov. 2016 Nov;6(11):1230-1236. Epub 2016 Sep 28.

28.

Endovascular management of internal carotid artery injuries secondary to endonasal surgery: case series and review of the literature.

Sylvester PT, Moran CJ, Derdeyn CP, Cross DT, Dacey RG, Zipfel GJ, Kim AH, Uppaluri R, Haughey BH, Tempelhoff R, Rich KM, Schneider J, Chole RA, Chicoine MR.

J Neurosurg. 2016 Nov;125(5):1256-1276. Epub 2016 Jan 15. Review.

PMID:
26771847
29.

Pd(II) adsorption characteristics of glutaraldehyde cross-linked chitosan copolymer resin.

Nagireddi S, Katiyar V, Uppaluri R.

Int J Biol Macromol. 2017 Jan;94(Pt A):72-84. doi: 10.1016/j.ijbiomac.2016.09.088. Epub 2016 Sep 27.

PMID:
27687631
30.

Neoantigens in immunotherapy and personalized vaccines: Implications for head and neck squamous cell carcinoma.

Zolkind P, Dunn GP, Lin T, Griffith M, Griffith OL, Uppaluri R.

Oral Oncol. 2017 Aug;71:169-176. doi: 10.1016/j.oraloncology.2016.09.010. Epub 2016 Oct 14. Review.

31.

nab-Paclitaxel, cisplatin, and 5-fluorouracil followed by concurrent cisplatin and radiation for head and neck squamous cell carcinoma.

Adkins D, Ley J, Michel L, Wildes TM, Thorstad W, Gay HA, Daly M, Rich J, Paniello R, Uppaluri R, Jackson R, Trinkaus K, Nussenbaum B.

Oral Oncol. 2016 Oct;61:1-7. doi: 10.1016/j.oraloncology.2016.07.015. Epub 2016 Jul 29.

32.

Head and neck cancer immunology and immunotherapeutics: Basic concepts to clinical translational approaches.

Uppaluri R, Bell RB, Sunwoo JB.

Oral Oncol. 2016 Jul;58:49-51. doi: 10.1016/j.oraloncology.2016.05.004. Epub 2016 May 26. No abstract available.

PMID:
27238227
33.

Enhanced Tumor Control with Combination mTOR and PD-L1 Inhibition in Syngeneic Oral Cavity Cancers.

Moore EC, Cash HA, Caruso AM, Uppaluri R, Hodge JW, Van Waes C, Allen CT.

Cancer Immunol Res. 2016 Jul;4(7):611-20. doi: 10.1158/2326-6066.CIR-15-0252. Epub 2016 Apr 13.

34.

Metastatic model of HPV+ oropharyngeal squamous cell carcinoma demonstrates heterogeneity in tumor metastasis.

Vermeer DW, Coppock JD, Zeng E, Lee KM, Spanos WC, Onken MD, Uppaluri R, Lee JH, Vermeer PD.

Oncotarget. 2016 Apr 26;7(17):24194-207. doi: 10.18632/oncotarget.8254.

35.

mTOR and MEK1/2 inhibition differentially modulate tumor growth and the immune microenvironment in syngeneic models of oral cavity cancer.

Cash H, Shah S, Moore E, Caruso A, Uppaluri R, Van Waes C, Allen C.

Oncotarget. 2015 Nov 3;6(34):36400-17. doi: 10.18632/oncotarget.5063.

36.

Juvenile xanthogranuloma of supra-sellar region: a rare presentation.

Stepan KO, Sharma A, Chicoine MR, Uppaluri R, Dahiya S.

Clin Neuropathol. 2015 Nov-Dec;34(6):368-70. doi: 10.5414/NP300854. No abstract available.

PMID:
26308252
37.

Genomic analysis to define molecular basis of aggressiveness in a mouse model of oral cancer.

Chalivendra V, Kanchi KL, Onken MD, Winkler AE, Mardis E, Uppaluri R.

Genom Data. 2015 Mar 1;3:61-62.

38.

Ethmoid sinus mass. Sinonasal teratocarcinosarcoma.

Yang Z, Uppaluri R, Lewis JS Jr.

JAMA Otolaryngol Head Neck Surg. 2015 Apr;141(4):389-90. doi: 10.1001/jamaoto.2015.22. No abstract available.

PMID:
25695742
39.

CD271 is a functional and targetable marker of tumor-initiating cells in head and neck squamous cell carcinoma.

Murillo-Sauca O, Chung MK, Shin JH, Karamboulas C, Kwok S, Jung YH, Oakley R, Tysome JR, Farnebo LO, Kaplan MJ, Sirjani D, Divi V, Holsinger FC, Tomeh C, Nichols A, Le QT, Colevas AD, Kong CS, Uppaluri R, Lewis JS Jr, Ailles LE, Sunwoo JB.

Oncotarget. 2014 Aug 30;5(16):6854-66.

40.

Electrochemical conversion of CO₂ to fuels: tuning of the reaction zone using suitable functional groups in a solid polymer electrolyte.

Aeshala LM, Uppaluri R, Verma A.

Phys Chem Chem Phys. 2014 Sep 7;16(33):17588-94. doi: 10.1039/c4cp02389g.

PMID:
25025524
41.

A surprising cross-species conservation in the genomic landscape of mouse and human oral cancer identifies a transcriptional signature predicting metastatic disease.

Onken MD, Winkler AE, Kanchi KL, Chalivendra V, Law JH, Rickert CG, Kallogjeri D, Judd NP, Dunn GP, Piccirillo JF, Lewis JS Jr, Mardis ER, Uppaluri R.

Clin Cancer Res. 2014 Jun 1;20(11):2873-84. doi: 10.1158/1078-0432.CCR-14-0205. Epub 2014 Mar 25.

42.

Combined high-field intraoperative magnetic resonance imaging and endoscopy increase extent of resection and progression-free survival for pituitary adenomas.

Sylvester PT, Evans JA, Zipfel GJ, Chole RA, Uppaluri R, Haughey BH, Getz AE, Silverstein J, Rich KM, Kim AH, Dacey RG, Chicoine MR.

Pituitary. 2015 Feb;18(1):72-85. doi: 10.1007/s11102-014-0560-2.

43.

Efficacy of reducing agent and surfactant contacting pattern on the performance characteristics of nickel electroless plating baths coupled with and without ultrasound.

Agarwal A, Pujari M, Uppaluri R, Verma A.

Ultrason Sonochem. 2014 Jul;21(4):1382-91. doi: 10.1016/j.ultsonch.2014.01.015. Epub 2014 Jan 21.

PMID:
24480601
44.

Identifying the initiating events of anti-Listeria responses using mice with conditional loss of IFN-γ receptor subunit 1 (IFNGR1).

Lee SH, Carrero JA, Uppaluri R, White JM, Archambault JM, Lai KS, Chan SR, Sheehan KC, Unanue ER, Schreiber RD.

J Immunol. 2013 Oct 15;191(8):4223-34. doi: 10.4049/jimmunol.1300910. Epub 2013 Sep 18.

45.

Emerging insights into head and neck cancer metastasis.

Allen CT, Law JH, Dunn GP, Uppaluri R.

Head Neck. 2013 Nov;35(11):1669-78. doi: 10.1002/hed.23202. Epub 2012 Dec 22. Review.

PMID:
23280716
46.

Cancer immunoediting by the innate immune system in the absence of adaptive immunity.

O'Sullivan T, Saddawi-Konefka R, Vermi W, Koebel CM, Arthur C, White JM, Uppaluri R, Andrews DM, Ngiow SF, Teng MW, Smyth MJ, Schreiber RD, Bui JD.

J Exp Med. 2012 Sep 24;209(10):1869-82. Epub 2012 Aug 27.

47.

Feasibility and effectiveness of provider initiated HIV testing and counseling of TB suspects in Vizianagaram district, South India.

Achanta S, Kumar AM, Nagaraja SB, Jaju J, Shamrao SR, Uppaluri R, Tekumalla RR, Gupta D, Kumar A, Satyanarayana S, Dewan PK.

PLoS One. 2012;7(7):e41378. doi: 10.1371/journal.pone.0041378. Epub 2012 Jul 23.

48.

Comparative analysis of tumor-infiltrating lymphocytes in a syngeneic mouse model of oral cancer.

Judd NP, Allen CT, Winkler AE, Uppaluri R.

Otolaryngol Head Neck Surg. 2012 Sep;147(3):493-500. doi: 10.1177/0194599812442037. Epub 2012 Mar 19.

49.

Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting.

Matsushita H, Vesely MD, Koboldt DC, Rickert CG, Uppaluri R, Magrini VJ, Arthur CD, White JM, Chen YS, Shea LK, Hundal J, Wendl MC, Demeter R, Wylie T, Allison JP, Smyth MJ, Old LJ, Mardis ER, Schreiber RD.

Nature. 2012 Feb 8;482(7385):400-4. doi: 10.1038/nature10755.

50.

The clinical implications of antitumor immunity in head and neck cancer.

Allen CT, Judd NP, Bui JD, Uppaluri R.

Laryngoscope. 2012 Jan;122(1):144-57. doi: 10.1002/lary.21913. Review.

PMID:
22183634

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