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Items: 25


Quelling germ cell pluripotency on the genital ridge.

Updike DL.

Proc Natl Acad Sci U S A. 2019 Nov 22. pii: 201918899. doi: 10.1073/pnas.1918899116. [Epub ahead of print] No abstract available.


Germline Maintenance Through the Multifaceted Activities of GLH/Vasa in Caenorhabditis elegans P Granules.

Marnik EA, Fuqua JH, Sharp CS, Rochester JD, Xu EL, Holbrook SE, Updike DL.

Genetics. 2019 Nov;213(3):923-939. doi: 10.1534/genetics.119.302670. Epub 2019 Sep 10.


Membraneless organelles: P granules in Caenorhabditis elegans.

Marnik EA, Updike DL.

Traffic. 2019 Jun;20(6):373-379. doi: 10.1111/tra.12644. Epub 2019 Apr 11. Review.


PQN-75 is expressed in the pharyngeal gland cells of Caenorhabditiselegans and is dispensable for germline development.

Rochester JD, Tanner PC, Sharp CS, Andralojc KM, Updike DL.

Biol Open. 2017 Sep 15;6(9):1355-1363. doi: 10.1242/bio.027987.


ELLI-1, a novel germline protein, modulates RNAi activity and P-granule accumulation in Caenorhabditis elegans.

Andralojc KM, Campbell AC, Kelly AL, Terrey M, Tanner PC, Gans IM, Senter-Zapata MJ, Khokhar ES, Updike DL.

PLoS Genet. 2017 Feb 9;13(2):e1006611. doi: 10.1371/journal.pgen.1006611. eCollection 2017 Feb.


A Forward Genetic Screen for Suppressors of Somatic P Granules in Caenorhabditis elegans.

Kelly AL, Senter-Zapata MJ, Campbell AC, Lust HE, Theriault ME, Andralojc KM, Updike DL.

G3 (Bethesda). 2015 Jun 22;5(10):2209-15. doi: 10.1534/g3.115.019257.


CSR-1 and P granules suppress sperm-specific transcription in the C. elegans germline.

Campbell AC, Updike DL.

Development. 2015 May 15;142(10):1745-55. doi: 10.1242/dev.121434.


Germ-granule components prevent somatic development in the C. elegans germline.

Updike DL, Knutson AK, Egelhofer TA, Campbell AC, Strome S.

Curr Biol. 2014 May 5;24(9):970-5. doi: 10.1016/j.cub.2014.03.015. Epub 2014 Apr 17.


A simple method for using silicone elastomer masks for quantitative analysis of cell migration without cellular damage or substrate disruption.

Sherry DM, Parks EE, Bullen EC, Updike DL, Howard EW.

Cell Adh Migr. 2013 Nov-Dec;7(6):469-75. doi: 10.4161/cam.27294. Epub 2013 Dec 2.


MMP-2 expression by fibroblasts is suppressed by the myofibroblast phenotype.

Howard EW, Crider BJ, Updike DL, Bullen EC, Parks EE, Haaksma CJ, Sherry DM, Tomasek JJ.

Exp Cell Res. 2012 Aug 1;318(13):1542-53. doi: 10.1016/j.yexcr.2012.03.007. Epub 2012 Mar 17.


P granules extend the nuclear pore complex environment in the C. elegans germ line.

Updike DL, Hachey SJ, Kreher J, Strome S.

J Cell Biol. 2011 Mar 21;192(6):939-48. doi: 10.1083/jcb.201010104. Epub 2011 Mar 14.


TGF-beta suppresses the upregulation of MMP-2 by vascular smooth muscle cells in response to PDGF-BB.

Risinger GM Jr, Updike DL, Bullen EC, Tomasek JJ, Howard EW.

Am J Physiol Cell Physiol. 2010 Jan;298(1):C191-201. doi: 10.1152/ajpcell.00417.2008. Epub 2009 Oct 21.


A genomewide RNAi screen for genes that affect the stability, distribution and function of P granules in Caenorhabditis elegans.

Updike DL, Strome S.

Genetics. 2009 Dec;183(4):1397-419. doi: 10.1534/genetics.109.110171. Epub 2009 Oct 5.


The Target of Rapamycin pathway antagonizes pha-4/FoxA to control development and aging.

Sheaffer KL, Updike DL, Mango SE.

Curr Biol. 2008 Sep 23;18(18):1355-64. doi: 10.1016/j.cub.2008.07.097.


Temporal regulation of foregut development by HTZ-1/H2A.Z and PHA-4/FoxA.

Updike DL, Mango SE.

PLoS Genet. 2006 Sep 29;2(9):e161. Epub 2006 Aug 11.


Matrix metalloproteinase-2 expression by vascular smooth muscle cells is mediated by both stimulatory and inhibitory signals in response to growth factors.

Risinger GM Jr, Hunt TS, Updike DL, Bullen EC, Howard EW.

J Biol Chem. 2006 Sep 8;281(36):25915-25. Epub 2006 Jul 19.


Transcriptional and posttranscriptional regulation of angiopoietin-2 expression mediated by IGF and PDGF in vascular smooth muscle cells.

Phelps ED, Updike DL, Bullen EC, Grammas P, Howard EW.

Am J Physiol Cell Physiol. 2006 Feb;290(2):C352-61. Epub 2005 Sep 21.


Genetic and biochemical basis for viability of yeast lacking mitochondrial genomes.

Kominsky DJ, Brownson MP, Updike DL, Thorsness PE.

Genetics. 2002 Dec;162(4):1595-604.


Maintenance of mitochondrial morphology is linked to maintenance of the mitochondrial genome in Saccharomyces cerevisiae.

Hanekamp T, Thorsness MK, Rebbapragada I, Fisher EM, Seebart C, Darland MR, Coxbill JA, Updike DL, Thorsness PE.

Genetics. 2002 Nov;162(3):1147-56.


Matrix metalloproteinases and the ontogeny of scarless repair: the other side of the wound healing balance.

Peled ZM, Phelps ED, Updike DL, Chang J, Krummel TM, Howard EW, Longaker MT.

Plast Reconstr Surg. 2002 Sep 1;110(3):801-11.


Gelatinase A expression in endothelial cells is regulated by at least two cis-acting promoter elements.

Bottles KD, Bullen EC, Updike DL, Vu TK, Phelps E, Grammas P, Howard EW.

Biochim Biophys Acta. 1999 Aug 5;1428(2-3):147-60.


Gelatinase A activation is regulated by the organization of the polymerized actin cytoskeleton.

Tomasek JJ, Halliday NL, Updike DL, Ahern-Moore JS, Vu TK, Liu RW, Howard EW.

J Biol Chem. 1997 Mar 14;272(11):7482-7.


Tissue inhibitor of metalloproteinases-1 is decreased and activated gelatinases are increased in chronic wounds.

Bullen EC, Longaker MT, Updike DL, Benton R, Ladin D, Hou Z, Howard EW.

J Invest Dermatol. 1995 Feb;104(2):236-40.

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