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Items: 40


Cryptococcus neoformans Chitin Synthase 3 Plays a Critical Role in Dampening Host Inflammatory Responses.

Hole CR, Lam WC, Upadhya R, Lodge JK.

mBio. 2020 Feb 18;11(1). pii: e03373-19. doi: 10.1128/mBio.03373-19.


Intranasally Administered Human MSC-Derived Extracellular Vesicles Pervasively Incorporate into Neurons and Microglia in both Intact and Status Epilepticus Injured Forebrain.

Kodali M, Castro OW, Kim DK, Thomas A, Shuai B, Attaluri S, Upadhya R, Gitai D, Madhu LN, Prockop DJ, Shetty AK.

Int J Mol Sci. 2019 Dec 26;21(1). pii: E181. doi: 10.3390/ijms21010181.


Extracellular Vesicles in the Forebrain Display Reduced miR-346 and miR-331-3p in a Rat Model of Chronic Temporal Lobe Epilepsy.

Gitaí DLG, Dos Santos YDR, Upadhya R, Kodali M, Madhu LN, Shetty AK.

Mol Neurobiol. 2019 Dec 7. doi: 10.1007/s12035-019-01797-1. [Epub ahead of print]


Monosodium luminol reinstates redox homeostasis, improves cognition, mood and neurogenesis, and alleviates neuro- and systemic inflammation in a model of Gulf War Illness.

Shetty AK, Attaluri S, Kodali M, Shuai B, Shetty GA, Upadhya D, Hattiangady B, Madhu LN, Upadhya R, Bates A, Rao X.

Redox Biol. 2020 Jan;28:101389. doi: 10.1016/j.redox.2019.101389. Epub 2019 Nov 18.


Purifying Low-Volume Combinatorial Polymer Libraries with Gel Filtration Columns.

Upadhya R, Kanagala MJ, Gormley AJ.

Macromol Rapid Commun. 2019 Dec;40(24):e1900528. doi: 10.1002/marc.201900528. Epub 2019 Nov 18.


Chitosan Biosynthesis and Virulence in the Human Fungal Pathogen Cryptococcus gattii.

Lam WC, Upadhya R, Specht CA, Ragsdale AE, Hole CR, Levitz SM, Lodge JK.

mSphere. 2019 Oct 9;4(5). pii: e00644-19. doi: 10.1128/mSphere.00644-19.


A Model of Chronic Temporal Lobe Epilepsy Presenting Constantly Rhythmic and Robust Spontaneous Seizures, Co-morbidities and Hippocampal Neuropathology.

Upadhya D, Kodali M, Gitai D, Castro OW, Zanirati G, Upadhya R, Attaluri S, Mitra E, Shuai B, Hattiangady B, Shetty AK.

Aging Dis. 2019 Oct 1;10(5):915-936. doi: 10.14336/AD.2019.0720. eCollection 2019 Oct.


Neuroinflammation in Gulf War Illness is linked with HMGB1 and complement activation, which can be discerned from brain-derived extracellular vesicles in the blood.

Madhu LN, Attaluri S, Kodali M, Shuai B, Upadhya R, Gitai D, Shetty AK.

Brain Behav Immun. 2019 Oct;81:430-443. doi: 10.1016/j.bbi.2019.06.040. Epub 2019 Jun 27.


Novel Insights on Systemic and Brain Aging, Stroke, Amyotrophic Lateral Sclerosis, and Alzheimer's Disease.

Shetty AK, Upadhya R, Madhu LN, Kodali M.

Aging Dis. 2019 Apr 1;10(2):470-482. doi: 10.14336/AD.2019.0330. eCollection 2019 Apr.


Novel Synthetic Polyamines Have Potent Antimalarial Activities in vitro and in vivo by Decreasing Intracellular Spermidine and Spermine Concentrations.

El Bissati K, Redel H, Ting LM, Lykins JD, McPhillie MJ, Upadhya R, Woster PM, Yarlett N, Kim K, Weiss LM.

Front Cell Infect Microbiol. 2019 Feb 14;9:9. doi: 10.3389/fcimb.2019.00009. eCollection 2019.


Emerging Anti-Aging Strategies - Scientific Basis and Efficacy.

Shetty AK, Kodali M, Upadhya R, Madhu LN.

Aging Dis. 2018 Dec 4;9(6):1165-1184. doi: 10.14336/AD.2018.1026. eCollection 2018 Dec. Review.


Neural stem cell derived extracellular vesicles: Attributes and prospects for treating neurodegenerative disorders.

Vogel A, Upadhya R, Shetty AK.

EBioMedicine. 2018 Dec;38:273-282. doi: 10.1016/j.ebiom.2018.11.026. Epub 2018 Nov 22. Review.


Cryptococcus neoformans Cda1 and Its Chitin Deacetylase Activity Are Required for Fungal Pathogenesis.

Upadhya R, Baker LG, Lam WC, Specht CA, Donlin MJ, Lodge JK.

mBio. 2018 Nov 20;9(6). pii: e02087-18. doi: 10.1128/mBio.02087-18.


Prospects of Cannabidiol for Easing Status Epilepticus-Induced Epileptogenesis and Related Comorbidities.

Upadhya D, Castro OW, Upadhya R, Shetty AK.

Mol Neurobiol. 2018 Aug;55(8):6956-6964. doi: 10.1007/s12035-018-0898-y. Epub 2018 Jan 25. Review.


A fluorogenic C. neoformans reporter strain with a robust expression of m-cherry expressed from a safe haven site in the genome.

Upadhya R, Lam WC, Maybruck BT, Donlin MJ, Chang AL, Kayode S, Ormerod KL, Fraser JA, Doering TL, Lodge JK.

Fungal Genet Biol. 2017 Nov;108:13-25. doi: 10.1016/j.fgb.2017.08.008. Epub 2017 Sep 12.


Continuous microfluidic assembly of biodegradable poly(beta-amino ester)/DNA nanoparticles for enhanced gene delivery.

Wilson DR, Mosenia A, Suprenant MP, Upadhya R, Routkevitch D, Meyer RA, Quinones-Hinojosa A, Green JJ.

J Biomed Mater Res A. 2017 Jun;105(6):1813-1825. doi: 10.1002/jbm.a.36033. Epub 2017 Apr 12.


KAP Study on HIV/AIDS Among Antenatal Women Attending Central Referral Hospital of North East India.

Lucksom PG, Upadhya R, Kharka L, Dubey S, Choudhary N, Yadav R.

J Obstet Gynaecol India. 2016 Oct;66(Suppl 1):55-9. doi: 10.1007/s13224-015-0767-9. Epub 2015 Sep 8.


Intracellular Action of a Secreted Peptide Required for Fungal Virulence.

Homer CM, Summers DK, Goranov AI, Clarke SC, Wiesner DL, Diedrich JK, Moresco JJ, Toffaletti D, Upadhya R, Caradonna I, Petnic S, Pessino V, Cuomo CA, Lodge JK, Perfect J, Yates JR 3rd, Nielsen K, Craik CS, Madhani HD.

Cell Host Microbe. 2016 Jun 8;19(6):849-64. doi: 10.1016/j.chom.2016.05.001. Epub 2016 May 19.


Induction of Protective Immunity to Cryptococcal Infection in Mice by a Heat-Killed, Chitosan-Deficient Strain of Cryptococcus neoformans.

Upadhya R, Lam WC, Maybruck B, Specht CA, Levitz SM, Lodge JK.

mBio. 2016 May 10;7(3). pii: e00547-16. doi: 10.1128/mBio.00547-16.


Toxoplasma gondii Arginine Methyltransferase 1 (PRMT1) Is Necessary for Centrosome Dynamics during Tachyzoite Cell Division.

El Bissati K, Suvorova ES, Xiao H, Lucas O, Upadhya R, Ma Y, Angeletti RH, White MW, Weiss LM, Kim K.

mBio. 2016 Feb 2;7(1):e02094-15. doi: 10.1128/mBio.02094-15.


Cross talk between the cell wall integrity and cyclic AMP/protein kinase A pathways in Cryptococcus neoformans.

Donlin MJ, Upadhya R, Gerik KJ, Lam W, VanArendonk LG, Specht CA, Sharma NK, Lodge JK.

mBio. 2014 Aug 12;5(4). pii: e01573-14. doi: 10.1128/mBio.01573-14.


Cryptococcus at work: gene expression during human infection.

Upadhya R, Donlin MJ, Lodge JK.

mBio. 2014 Apr 22;5(2):e01097. doi: 10.1128/mBio.01097-14.


The art and science of medical interpretation: accessibility and lack of bias are both crucial.

Upadhya R.

Am J Nurs. 2013 Nov;113(11):11. doi: 10.1097/01.NAJ.0000437091.84748.a0. No abstract available.


Sulphiredoxin plays peroxiredoxin-dependent and -independent roles via the HOG signalling pathway in Cryptococcus neoformans and contributes to fungal virulence.

Upadhya R, Kim H, Jung KW, Park G, Lam W, Lodge JK, Bahn YS.

Mol Microbiol. 2013 Nov;90(3):630-648. doi: 10.1111/mmi.12388. Epub 2013 Oct 3.


Global transcriptome profile of Cryptococcus neoformans during exposure to hydrogen peroxide induced oxidative stress.

Upadhya R, Campbell LT, Donlin MJ, Aurora R, Lodge JK.

PLoS One. 2013;8(1):e55110. doi: 10.1371/journal.pone.0055110. Epub 2013 Jan 28.


Response of adipose tissue to early infection with Trypanosoma cruzi (Brazil strain).

Nagajyothi F, Desruisseaux MS, Machado FS, Upadhya R, Zhao D, Schwartz GJ, Teixeira MM, Albanese C, Lisanti MP, Chua SC Jr, Weiss LM, Scherer PE, Tanowitz HB.

J Infect Dis. 2012 Mar 1;205(5):830-40. doi: 10.1093/infdis/jir840. Epub 2012 Jan 31.


Analysis of the glycoproteome of Toxoplasma gondii using lectin affinity chromatography and tandem mass spectrometry.

Luo Q, Upadhya R, Zhang H, Madrid-Aliste C, Nieves E, Kim K, Angeletti RH, Weiss LM.

Microbes Infect. 2011 Dec;13(14-15):1199-210. doi: 10.1016/j.micinf.2011.08.013. Epub 2011 Aug 31.


γ-radiation induces cellular sensitivity and aberrant methylation in human tumor cell lines.

Kumar A, Rai PS, Upadhya R, Vishwanatha, Prasada KS, Rao BS, Satyamoorthy K.

Int J Radiat Biol. 2011 Nov;87(11):1086-96. doi: 10.3109/09553002.2011.605417. Epub 2011 Sep 7.


Evaluation of pharmacokinetic, biodistribution, pharmacodynamic, and toxicity profile of free juglone and its sterically stabilized liposomes.

Aithal BK, Sunil Kumar MR, Rao BN, Upadhya R, Prabhu V, Shavi G, Arumugam K, Sajankila SP, Udupa N, Satyamoorthy K, Satish Rao BS.

J Pharm Sci. 2011 Aug;100(8):3517-3528. doi: 10.1002/jps.22573. Epub 2011 Apr 26.


Improved techniques for endogenous epitope tagging and gene deletion in Toxoplasma gondii.

Upadhya R, Kim K, Hogue-Angeletti R, Weiss LM.

J Microbiol Methods. 2011 May;85(2):103-13. doi: 10.1016/j.mimet.2011.02.001. Epub 2011 Feb 23.


Plasma protein oxidation in patients with brain tumors.

Kumar P, Devi U, Ali S, Upadhya R, Pillai S, Raja A, Rao S, Rao A.

Neurol Res. 2009 Apr;31(3):270-3. doi: 10.1179/174313209X382296. Epub 2008 Nov 26.


Susceptibility of peripheral lymphocytes of brain tumour patients to in vitro radiation-induced DNA damage, a preliminary study.

Kalthur G, Kumar P, Devi U, Ali S, Upadhya R, Pillai S, Rao A.

Clin Exp Med. 2008 Sep;8(3):147-50. doi: 10.1007/s10238-008-0171-1. Epub 2008 Sep 13.


Pair-wise interactions of polymerization inhibitory contact site mutations of hemoglobin-S.

Srinivasulu S, Perumalsamy K, Upadhya R, Manjula BN, Feiring S, Alami R, Bouhassira E, Fabry ME, Nagel RL, Acharya AS.

Protein J. 2006 Dec;25(7-8):503-16.


System for expression of microsporidian methionine amino peptidase type 2 (MetAP2) in the yeast Saccharomyces cerevisiae.

Upadhya R, Zhang HS, Weiss LM.

Antimicrob Agents Chemother. 2006 Oct;50(10):3389-95. Epub 2006 Aug 17.


Two steps in Maf1-dependent repression of transcription by RNA polymerase III.

Desai N, Lee J, Upadhya R, Chu Y, Moir RD, Willis IM.

J Biol Chem. 2005 Feb 25;280(8):6455-62. Epub 2004 Dec 8.


Signaling repression of transcription by RNA polymerase III in yeast.

Willis IM, Desai N, Upadhya R.

Prog Nucleic Acid Res Mol Biol. 2004;77:323-53. Review. No abstract available.


Site-specific PEGylation of hemoglobin at Cys-93(beta): correlation between the colligative properties of the PEGylated protein and the length of the conjugated PEG chain.

Manjula BN, Tsai A, Upadhya R, Perumalsamy K, Smith PK, Malavalli A, Vandegriff K, Winslow RM, Intaglietta M, Prabhakaran M, Friedman JM, Acharya AS.

Bioconjug Chem. 2003 Mar-Apr;14(2):464-72.


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