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Items: 37


Clinical Significance of AR-V567es in Prostate Cancer-Letter.

Uo T, Plymate SR.

Clin Cancer Res. 2019 Oct 1;25(19):6009. doi: 10.1158/1078-0432.CCR-19-1400. No abstract available.


The androgen receptor regulates a druggable translational regulon in advanced prostate cancer.

Liu Y, Horn JL, Banda K, Goodman AZ, Lim Y, Jana S, Arora S, Germanos AA, Wen L, Hardin WR, Yang YC, Coleman IM, Tharakan RG, Cai EY, Uo T, Pillai SPS, Corey E, Morrissey C, Chen Y, Carver BS, Plymate SR, Beronja S, Nelson PS, Hsieh AC.

Sci Transl Med. 2019 Jul 31;11(503). pii: eaaw4993. doi: 10.1126/scitranslmed.aaw4993.


ARv7 Represses Tumor-Suppressor Genes in Castration-Resistant Prostate Cancer.

Cato L, de Tribolet-Hardy J, Lee I, Rottenberg JT, Coleman I, Melchers D, Houtman R, Xiao T, Li W, Uo T, Sun S, Kuznik NC, Göppert B, Ozgun F, van Royen ME, Houtsmuller AB, Vadhi R, Rao PK, Li L, Balk SP, Den RB, Trock BJ, Karnes RJ, Jenkins RB, Klein EA, Davicioni E, Gruhl FJ, Long HW, Liu XS, Cato ACB, Lack NA, Nelson PS, Plymate SR, Groner AC, Brown M.

Cancer Cell. 2019 Mar 18;35(3):401-413.e6. doi: 10.1016/j.ccell.2019.01.008. Epub 2019 Feb 14.


Inhibition of de novo lipogenesis targets androgen receptor signaling in castration-resistant prostate cancer.

Zadra G, Ribeiro CF, Chetta P, Ho Y, Cacciatore S, Gao X, Syamala S, Bango C, Photopoulos C, Huang Y, Tyekucheva S, Bastos DC, Tchaicha J, Lawney B, Uo T, D'Anello L, Csibi A, Kalekar R, Larimer B, Ellis L, Butler LM, Morrissey C, McGovern K, Palombella VJ, Kutok JL, Mahmood U, Bosari S, Adams J, Peluso S, Dehm SM, Plymate SR, Loda M.

Proc Natl Acad Sci U S A. 2019 Jan 8;116(2):631-640. doi: 10.1073/pnas.1808834116. Epub 2018 Dec 21.


Androgen receptor splice variant-7 expression emerges with castration resistance in prostate cancer.

Sharp A, Coleman I, Yuan W, Sprenger C, Dolling D, Rodrigues DN, Russo JW, Figueiredo I, Bertan C, Seed G, Riisnaes R, Uo T, Neeb A, Welti J, Morrissey C, Carreira S, Luo J, Nelson PS, Balk SP, True LD, de Bono JS, Plymate SR.

J Clin Invest. 2019 Jan 2;129(1):192-208. doi: 10.1172/JCI122819. Epub 2018 Nov 26.


Neuronal susceptibility to beta-amyloid toxicity and ischemic injury involves histone deacetylase-2 regulation of endophilin-B1.

Wang DB, Kinoshita C, Kinoshita Y, Sopher BL, Uo T, Lee RJ, Kim JK, Murphy SP, Dirk Keene C, Garden GA, Morrison RS.

Brain Pathol. 2019 Mar;29(2):164-175. doi: 10.1111/bpa.12647. Epub 2018 Oct 5.


The potential of AR-V7 as a therapeutic target.

Uo T, Plymate SR, Sprenger CC.

Expert Opin Ther Targets. 2018 Mar;22(3):201-216. doi: 10.1080/14728222.2018.1439016. Epub 2018 Feb 15. Review.


Androgen Receptor Variants and Castration-resistant Prostate Cancer: Looking Back and Looking Forward.

Uo T, Sprenger C.

Eur Urol. 2018 May;73(5):724-726. doi: 10.1016/j.eururo.2017.12.020. Epub 2018 Jan 3. No abstract available.


Allosteric alterations in the androgen receptor and activity in prostate cancer.

Uo T, Plymate SR, Sprenger CC.

Endocr Relat Cancer. 2017 Sep;24(9):R335-R348. doi: 10.1530/ERC-17-0108. Review.


Systematic and functional characterization of novel androgen receptor variants arising from alternative splicing in the ligand-binding domain.

Uo T, Dvinge H, Sprenger CC, Bradley RK, Nelson PS, Plymate SR.

Oncogene. 2017 Mar;36(10):1440-1450. doi: 10.1038/onc.2016.313. Epub 2016 Oct 3.


Androgen receptor splice variant V7 (AR-V7) in circulating tumor cells: a coming of age for AR splice variants?

Sprenger C, Uo T, Plymate S.

Ann Oncol. 2015 Sep;26(9):1805-7. doi: 10.1093/annonc/mdv311. Epub 2015 Jul 21. No abstract available.


Loss of endophilin-B1 exacerbates Alzheimer's disease pathology.

Wang DB, Kinoshita Y, Kinoshita C, Uo T, Sopher BL, Cudaback E, Keene CD, Bilousova T, Gylys K, Case A, Jayadev S, Wang HG, Garden GA, Morrison RS.

Brain. 2015 Jul;138(Pt 7):2005-19. doi: 10.1093/brain/awv128. Epub 2015 May 16.


MED1 mediates androgen receptor splice variant induced gene expression in the absence of ligand.

Liu G, Sprenger C, Wu PJ, Sun S, Uo T, Haugk K, Epilepsia KS, Plymate S.

Oncotarget. 2015 Jan 1;6(1):288-304.


Bax interacting factor-1 promotes survival and mitochondrial elongation in neurons.

Wang DB, Uo T, Kinoshita C, Sopher BL, Lee RJ, Murphy SP, Kinoshita Y, Garden GA, Wang HG, Morrison RS.

J Neurosci. 2014 Feb 12;34(7):2674-83. doi: 10.1523/JNEUROSCI.4074-13.2014.


MS-275, a class I histone deacetylase inhibitor, protects the p53-deficient mouse against ischemic injury.

Murphy SP, Lee RJ, McClean ME, Pemberton HE, Uo T, Morrison RS, Bastian C, Baltan S.

J Neurochem. 2014 May;129(3):509-15. doi: 10.1111/jnc.12498. Epub 2013 Nov 6.


A Bcl-xL-Drp1 complex regulates synaptic vesicle membrane dynamics during endocytosis.

Li H, Alavian KN, Lazrove E, Mehta N, Jones A, Zhang P, Licznerski P, Graham M, Uo T, Guo J, Rahner C, Duman RS, Morrison RS, Jonas EA.

Nat Cell Biol. 2013 Jul;15(7):773-85. doi: 10.1038/ncb2791. Epub 2013 Jun 23.


Transcription factor p53 influences microglial activation phenotype.

Jayadev S, Nesser NK, Hopkins S, Myers SJ, Case A, Lee RJ, Seaburg LA, Uo T, Murphy SP, Morrison RS, Garden GA.

Glia. 2011 Oct;59(10):1402-13. doi: 10.1002/glia.21178. Epub 2011 May 19.


A syngeneic glioma model to assess the impact of neural progenitor target cell age on tumor malignancy.

Mikheev AM, Stoll EA, Mikheeva SA, Maxwell JP, Jankowski PP, Ray S, Uo T, Morrison RS, Horner PJ, Rostomily RC.

Aging Cell. 2009 Aug;8(4):499-501. doi: 10.1111/j.1474-9726.2009.00494.x. Epub 2009 May 31.


Drp1 levels constitutively regulate mitochondrial dynamics and cell survival in cortical neurons.

Uo T, Dworzak J, Kinoshita C, Inman DM, Kinoshita Y, Horner PJ, Morrison RS.

Exp Neurol. 2009 Aug;218(2):274-85. doi: 10.1016/j.expneurol.2009.05.010. Epub 2009 May 13.


Histone deacetylase inhibitors prevent p53-dependent and p53-independent Bax-mediated neuronal apoptosis through two distinct mechanisms.

Uo T, Veenstra TD, Morrison RS.

J Neurosci. 2009 Mar 4;29(9):2824-32. doi: 10.1523/JNEUROSCI.6186-08.2009.


Serine racemase with catalytically active lysinoalanyl residue.

Yamauchi T, Goto M, Wu HY, Uo T, Yoshimura T, Mihara H, Kurihara T, Miyahara I, Hirotsu K, Esaki N.

J Biochem. 2009 Apr;145(4):421-4. doi: 10.1093/jb/mvp010. Epub 2009 Jan 20.


Proteomic analysis of protein expression changes in a model of gliomagenesis.

McBee JK, Yu LR, Kinoshita Y, Uo T, Beyer RP, Veenstra TD, Morrison RS.

Proteomics Clin Appl. 2007 Nov;1(11):1485-98. doi: 10.1002/prca.200700292.


Potential applications and limitations of proteomics in the study of neurological disease.

Kinoshita Y, Uo T, Jayadev S, Garden GA, Conrads TP, Veenstra TD, Morrison RS.

Arch Neurol. 2006 Dec;63(12):1692-6. Review. No abstract available.


Pescadillo interacts with the cadmium response element of the human heme oxygenase-1 promoter in renal epithelial cells.

Sikorski EM, Uo T, Morrison RS, Agarwal A.

J Biol Chem. 2006 Aug 25;281(34):24423-30. Epub 2006 Jun 30.


Physiological role of D-amino acid-N-acetyltransferase of Saccharomyces cerevisiae: detoxification of D-amino acids.

Yow GY, Uo T, Yoshimura T, Esaki N.

Arch Microbiol. 2006 Mar;185(1):39-46. Epub 2005 Dec 14.


The proteomics of neurodegeneration.

Johnson MD, Yu LR, Conrads TP, Kinoshita Y, Uo T, McBee JK, Veenstra TD, Morrison RS.

Am J Pharmacogenomics. 2005;5(4):259-70. Review.


Neurons exclusively express N-Bak, a BH3 domain-only Bak isoform that promotes neuronal apoptosis.

Uo T, Kinoshita Y, Morrison RS.

J Biol Chem. 2005 Mar 11;280(10):9065-73. Epub 2004 Dec 8.


Evaluation of the acid-cleavable isotope-coded affinity tag reagents: application to camptothecin-treated cortical neurons.

Yu LR, Conrads TP, Uo T, Issaq HJ, Morrison RS, Veenstra TD.

J Proteome Res. 2004 May-Jun;3(3):469-77.


Global analysis of the cortical neuron proteome.

Yu LR, Conrads TP, Uo T, Kinoshita Y, Morrison RS, Lucas DA, Chan KC, Blonder J, Issaq HJ, Veenstra TD.

Mol Cell Proteomics. 2004 Sep;3(9):896-907. Epub 2004 Jun 30.


Proteome analysis of DNA damage-induced neuronal death using high throughput mass spectrometry.

Johnson MD, Yu LR, Conrads TP, Kinoshita Y, Uo T, Matthews JD, Lee SW, Smith RD, Veenstra TD, Morrison RS.

J Biol Chem. 2004 Jun 18;279(25):26685-97. Epub 2004 Apr 1.


Gene cloning, purification, and characterization of 2,3-diaminopropionate ammonia-lyase from Escherichia coli.

Uo T, Yoshimura T, Nishiyama T, Esaki N.

Biosci Biotechnol Biochem. 2002 Dec;66(12):2639-44.


Proteomic analysis in the neurosciences.

Morrison RS, Kinoshita Y, Johnson MD, Uo T, Ho JT, McBee JK, Conrads TP, Veenstra TD.

Mol Cell Proteomics. 2002 Aug;1(8):553-60. Review.


Id proteins at the cross-road of development and cancer.

Lasorella A, Uo T, Iavarone A.

Oncogene. 2001 Dec 20;20(58):8326-33. Review.


Occurrence of pyridoxal 5'-phosphate-dependent serine racemase in silkworm, Bombyx mori.

Uo T, Yoshimura T, Shimizu S, Esaki N.

Biochem Biophys Res Commun. 1998 May 8;246(1):31-4.


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