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Items: 1 to 50 of 197

1.

A Case of Drug-Induced Proximal Tubular Dysfunction.

Hall AM, Unwin RJ.

Clin J Am Soc Nephrol. 2019 Jun 10. pii: CJN.01430219. doi: 10.2215/CJN.01430219. [Epub ahead of print] No abstract available.

PMID:
31182554
2.

A preliminary survey of practice patterns across several European kidney stone centers and a call for action in developing shared practice.

Ferraro PM, Arrabal-Polo MÁ, Capasso G, Croppi E, Cupisti A, Ernandez T, Fuster DG, Galan JA, Grases F, Hoorn EJ, Knauf F, Letavernier E, Mohebbi N, Moochhala S, Petkova K, Pozdzik A, Sayer J, Seitz C, Strazzullo P, Trinchieri A, Vezzoli G, Vitale C, Vogt L, Unwin RJ, Bonny O, Gambaro G.

Urolithiasis. 2019 Jun;47(3):219-224. doi: 10.1007/s00240-019-01119-z. Epub 2019 Mar 8.

PMID:
30848320
3.

Physiological regulation of phosphate by vitamin D, parathyroid hormone (PTH) and phosphate (Pi).

Jacquillet G, Unwin RJ.

Pflugers Arch. 2019 Jan;471(1):83-98. doi: 10.1007/s00424-018-2231-z. Epub 2018 Nov 5. Review.

4.

The renal and blood pressure response to low sodium diet in P2X4 receptor knockout mice.

Craigie E, Menzies RI, Larsen CK, Jacquillet G, Carrel M, Wildman SS, Loffing J, Leipziger J, Shirley DG, Bailey MA, Unwin RJ.

Physiol Rep. 2018 Oct;6(20):e13899. doi: 10.14814/phy2.13899.

5.

Acute saccharin infusion has no effect on renal glucose handling in normal rats in vivo.

Jacquillet G, Debnam ES, Unwin RJ, Marks J.

Physiol Rep. 2018 Jul;6(14):e13804. doi: 10.14814/phy2.13804.

6.

Liquorice, Liddle, Bartter or Gitelman-how to differentiate?

Mumford E, Unwin RJ, Walsh SB.

Nephrol Dial Transplant. 2019 Jan 1;34(1):38-39. doi: 10.1093/ndt/gfy199.

PMID:
29982819
7.

Glycine Amidinotransferase (GATM), Renal Fanconi Syndrome, and Kidney Failure.

Reichold M, Klootwijk ED, Reinders J, Otto EA, Milani M, Broeker C, Laing C, Wiesner J, Devi S, Zhou W, Schmitt R, Tegtmeier I, Sterner C, Doellerer H, Renner K, Oefner PJ, Dettmer K, Simbuerger JM, Witzgall R, Stanescu HC, Dumitriu S, Iancu D, Patel V, Mozere M, Tekman M, Jaureguiberry G, Issler N, Kesselheim A, Walsh SB, Gale DP, Howie AJ, Martins JR, Hall AM, Kasgharian M, O'Brien K, Ferreira CR, Atwal PS, Jain M, Hammers A, Charles-Edwards G, Choe CU, Isbrandt D, Cebrian-Serrano A, Davies B, Sandford RN, Pugh C, Konecki DS, Povey S, Bockenhauer D, Lichter-Konecki U, Gahl WA, Unwin RJ, Warth R, Kleta R.

J Am Soc Nephrol. 2018 Jul;29(7):1849-1858. doi: 10.1681/ASN.2017111179. Epub 2018 Apr 13.

8.

P2X7 receptor antagonism ameliorates renal dysfunction in a rat model of sepsis.

Arulkumaran N, Sixma ML, Pollen S, Ceravola E, Jentho E, Prendecki M, Bass PS, Tam FWK, Unwin RJ, Singer M.

Physiol Rep. 2018 Mar;6(5). doi: 10.14814/phy2.13622.

9.

Renal Tubular Cell Mitochondrial Dysfunction Occurs Despite Preserved Renal Oxygen Delivery in Experimental Septic Acute Kidney Injury.

Arulkumaran N, Pollen S, Greco E, Courtneidge H, Hall AM, Duchen MR, Tam FWK, Unwin RJ, Singer M.

Crit Care Med. 2018 Apr;46(4):e318-e325. doi: 10.1097/CCM.0000000000002937.

10.

A more tubulocentric view of diabetic kidney disease.

Zeni L, Norden AGW, Cancarini G, Unwin RJ.

J Nephrol. 2017 Dec;30(6):701-717. doi: 10.1007/s40620-017-0423-9. Epub 2017 Aug 24. Review.

11.

Hyperglycemia-induced Renal P2X7 Receptor Activation Enhances Diabetes-related Injury.

Menzies RI, Booth JWR, Mullins JJ, Bailey MA, Tam FWK, Norman JT, Unwin RJ.

EBioMedicine. 2017 May;19:73-83. doi: 10.1016/j.ebiom.2017.04.011. Epub 2017 Apr 20.

12.

Sequential Analysis of a Panel of Biomarkers and Pathologic Findings in a Resuscitated Rat Model of Sepsis and Recovery.

Arulkumaran N, Sixma ML, Jentho E, Ceravola E, Bass PS, Kellum JA, Unwin RJ, Tam FWK, Singer M.

Crit Care Med. 2017 Aug;45(8):e821-e830. doi: 10.1097/CCM.0000000000002381.

13.

Postprandial adjustments in renal phosphate excretion do not involve a gut-derived phosphaturic factor.

Lee GJ, Mossa-Al Hashimi L, Debnam ES, Unwin RJ, Marks J.

Exp Physiol. 2017 Apr 1;102(4):462-474. doi: 10.1113/EP086062. Epub 2017 Mar 14.

14.

Vitamin D deficiency is prevalent among idiopathic stone formers, but does correction pose any risk?

Johri N, Jaeger P, Ferraro PM, Shavit L, Nair D, Robertson WG, Gambaro G, Unwin RJ.

Urolithiasis. 2017 Dec;45(6):535-543. doi: 10.1007/s00240-016-0954-x. Epub 2016 Dec 16.

15.

Putative tissue location and function of the SLC5 family member SGLT3.

Soták M, Marks J, Unwin RJ.

Exp Physiol. 2017 Jan 1;102(1):5-13. doi: 10.1113/EP086042. Review.

16.

Purinergic signaling in kidney disease.

Menzies RI, Tam FW, Unwin RJ, Bailey MA.

Kidney Int. 2017 Feb;91(2):315-323. doi: 10.1016/j.kint.2016.08.029. Epub 2016 Oct 22. Review.

17.

Infrared vibrational spectroscopy: a rapid and novel diagnostic and monitoring tool for cystinuria.

Oliver KV, Vilasi A, Maréchal A, Moochhala SH, Unwin RJ, Rich PR.

Sci Rep. 2016 Oct 10;6:34737. doi: 10.1038/srep34737.

18.

Experimental type II diabetes and related models of impaired glucose metabolism differentially regulate glucose transporters at the proximal tubule brush border membrane.

Chichger H, Cleasby ME, Srai SK, Unwin RJ, Debnam ES, Marks J.

Exp Physiol. 2016 Jun 1;101(6):731-42. doi: 10.1113/EP085670. Epub 2016 May 10.

19.

Persistent severe polyuria after renal transplant.

Wong T, Laing C, Ekong R, Povey S, Unwin RJ.

Clin Kidney J. 2016 Apr;9(2):180-3. doi: 10.1093/ckj/sfv100. Epub 2015 Oct 20.

20.

Magnesium: The Disregarded Cation.

Walsh SB, Zdebik AA, Unwin RJ.

Mayo Clin Proc. 2015 Aug;90(8):993-5. doi: 10.1016/j.mayocp.2015.06.011. No abstract available.

PMID:
26250724
21.

Inhibition of the purinergic P2X7 receptor improves renal perfusion in angiotensin-II-infused rats.

Menzies RI, Howarth AR, Unwin RJ, Tam FW, Mullins JJ, Bailey MA.

Kidney Int. 2015 Nov;88(5):1079-87. doi: 10.1038/ki.2015.182. Epub 2015 Jun 24.

22.

What is nephrocalcinosis?

Shavit L, Jaeger P, Unwin RJ.

Kidney Int. 2015 Jul;88(1):35-43. doi: 10.1038/ki.2015.76. Epub 2015 Mar 25. Review.

PMID:
25807034
23.

Experimental and regional variations in Na+-dependent and Na+-independent phosphate transport along the rat small intestine and colon.

Marks J, Lee GJ, Nadaraja SP, Debnam ES, Unwin RJ.

Physiol Rep. 2015 Jan 27;3(1). pii: e12281. doi: 10.14814/phy2.12281. Print 2015 Jan 1.

24.

A London experience 1995-2012: demographic, dietary and biochemical characteristics of a large adult cohort of patients with renal stone disease.

Ferraro PM, Robertson WG, Johri N, Nair A, Gambaro G, Shavit L, Moochhala SH, Unwin RJ.

QJM. 2015 Jul;108(7):561-8. doi: 10.1093/qjmed/hcu251. Epub 2014 Dec 17.

PMID:
25524906
25.

Renal Fanconi syndrome: taking a proximal look at the nephron.

Klootwijk ED, Reichold M, Unwin RJ, Kleta R, Warth R, Bockenhauer D.

Nephrol Dial Transplant. 2015 Sep;30(9):1456-60. doi: 10.1093/ndt/gfu377. Epub 2014 Dec 9. Review.

PMID:
25492894
26.

Renal P2 receptors and hypertension.

Menzies RI, Unwin RJ, Bailey MA.

Acta Physiol (Oxf). 2015 Jan;213(1):232-41. doi: 10.1111/apha.12412. Epub 2014 Nov 12. Review.

PMID:
25345692
27.

The urinary proteome and metabonome differ from normal in adults with mitochondrial disease.

Hall AM, Vilasi A, Garcia-Perez I, Lapsley M, Alston CL, Pitceathly RD, McFarland R, Schaefer AM, Turnbull DM, Beaumont NJ, Hsuan JJ, Cutillas PR, Lindon JC, Holmes E, Unwin RJ, Taylor RW, Gorman GS, Rahman S, Hanna MG.

Kidney Int. 2015 Mar;87(3):610-22. doi: 10.1038/ki.2014.297. Epub 2014 Sep 10.

PMID:
25207879
28.

Urine retinol-binding protein 4: a functional biomarker of the proximal renal tubule.

Norden AG, Lapsley M, Unwin RJ.

Adv Clin Chem. 2014;63:85-122. Review.

PMID:
24783352
29.

Exaggerated renal fibrosis in P2X4 receptor-deficient mice following unilateral ureteric obstruction.

Kim MJ, Turner CM, Hewitt R, Smith J, Bhangal G, Pusey CD, Unwin RJ, Tam FW.

Nephrol Dial Transplant. 2014 Jul;29(7):1350-61. doi: 10.1093/ndt/gfu019. Epub 2014 Feb 25.

30.

Is the inflammasome a potential therapeutic target in renal disease?

Turner CM, Arulkumaran N, Singer M, Unwin RJ, Tam FW.

BMC Nephrol. 2014 Jan 23;15:21. doi: 10.1186/1471-2369-15-21.

31.

Mistargeting of peroxisomal EHHADH and inherited renal Fanconi's syndrome.

Klootwijk ED, Reichold M, Helip-Wooley A, Tolaymat A, Broeker C, Robinette SL, Reinders J, Peindl D, Renner K, Eberhart K, Assmann N, Oefner PJ, Dettmer K, Sterner C, Schroeder J, Zorger N, Witzgall R, Reinhold SW, Stanescu HC, Bockenhauer D, Jaureguiberry G, Courtneidge H, Hall AM, Wijeyesekera AD, Holmes E, Nicholson JK, O'Brien K, Bernardini I, Krasnewich DM, Arcos-Burgos M, Izumi Y, Nonoguchi H, Jia Y, Reddy JK, Ilyas M, Unwin RJ, Gahl WA, Warth R, Kleta R.

N Engl J Med. 2014 Jan 9;370(2):129-38. doi: 10.1056/NEJMoa1307581.

32.

Drug-induced renal Fanconi syndrome.

Hall AM, Bass P, Unwin RJ.

QJM. 2014 Apr;107(4):261-9. doi: 10.1093/qjmed/hct258. Epub 2013 Dec 24. Review.

PMID:
24368854
33.

Effect of P2X4 and P2X7 receptor antagonism on the pressure diuresis relationship in rats.

Menzies RI, Unwin RJ, Dash RK, Beard DA, Cowley AW Jr, Carlson BE, Mullins JJ, Bailey MA.

Front Physiol. 2013 Oct 25;4:305. doi: 10.3389/fphys.2013.00305. eCollection 2013.

34.

The relationship between P2X4 and P2X7: a physiologically important interaction?

Craigie E, Birch RE, Unwin RJ, Wildman SS.

Front Physiol. 2013 Aug 15;4:216. doi: 10.3389/fphys.2013.00216. eCollection 2013.

35.

The role of the gastrointestinal tract in phosphate homeostasis in health and chronic kidney disease.

Marks J, Debnam ES, Unwin RJ.

Curr Opin Nephrol Hypertens. 2013 Jul;22(4):481-7. doi: 10.1097/MNH.0b013e3283621310. Review.

36.

Nephrocalcinosis (enamel renal syndrome) caused by autosomal recessive FAM20A mutations.

Jaureguiberry G, De la Dure-Molla M, Parry D, Quentric M, Himmerkus N, Koike T, Poulter J, Klootwijk E, Robinette SL, Howie AJ, Patel V, Figueres ML, Stanescu HC, Issler N, Nicholson JK, Bockenhauer D, Laing C, Walsh SB, McCredie DA, Povey S, Asselin A, Picard A, Coulomb A, Medlar AJ, Bailleul-Forestier I, Verloes A, Le Caignec C, Roussey G, Guiol J, Isidor B, Logan C, Shore R, Johnson C, Inglehearn C, Al-Bahlani S, Schmittbuhl M, Clauss F, Huckert M, Laugel V, Ginglinger E, Pajarola S, Spartà G, Bartholdi D, Rauch A, Addor MC, Yamaguti PM, Safatle HP, Acevedo AC, Martelli-Júnior H, dos Santos Netos PE, Coletta RD, Gruessel S, Sandmann C, Ruehmann D, Langman CB, Scheinman SJ, Ozdemir-Ozenen D, Hart TC, Hart PS, Neugebauer U, Schlatter E, Houillier P, Gahl WA, Vikkula M, Bloch-Zupan A, Bleich M, Kitagawa H, Unwin RJ, Mighell A, Berdal A, Kleta R.

Nephron Physiol. 2012;122(1-2):1-6. doi: 10.1159/000349989. Epub 2013 Feb 23.

37.

ATP and arterial calcification.

Fish RS, Klootwijk E, Tam FW, Kleta R, Wheeler DC, Unwin RJ, Norman J.

Eur J Clin Invest. 2013 Apr;43(4):405-12. doi: 10.1111/eci.12055. Epub 2013 Feb 10. Review.

PMID:
23398250
38.

Urinary vesicles: in splendid isolation.

Jacquillet G, Hoorn EJ, Vilasi A, Unwin RJ.

Nephrol Dial Transplant. 2013 Jun;28(6):1332-5. doi: 10.1093/ndt/gfs599. Epub 2013 Jan 24. No abstract available.

PMID:
23348883
39.

Protease stimulation of renal sodium reabsorption in vivo by activation of the collecting duct epithelial sodium channel (ENaC).

Jacquillet G, Chichger H, Unwin RJ, Shirley DG.

Nephrol Dial Transplant. 2013 Apr;28(4):839-45. doi: 10.1093/ndt/gfs486. Epub 2012 Dec 4.

PMID:
23222417
40.

Renal tubular disorders.

Walsh SB, Unwin RJ.

Clin Med (Lond). 2012 Oct;12(5):476-9. No abstract available.

41.

P2X7 receptor-mediated Nlrp3-inflammasome activation is a genetic determinant of macrophage-dependent crescentic glomerulonephritis.

Deplano S, Cook HT, Russell R, Franchi L, Schneiter S, Bhangal G, Unwin RJ, Pusey CD, Tam FW, Behmoaras J.

J Leukoc Biol. 2013 Jan;93(1):127-34. doi: 10.1189/jlb.0612284. Epub 2012 Oct 22.

42.

Retinoic acid receptor-dependent, cell-autonomous, endogenous retinoic acid signaling and its target genes in mouse collecting duct cells.

Wong YF, Wilson PD, Unwin RJ, Norman JT, Arno M, Hendry BM, Xu Q.

PLoS One. 2012;7(9):e45725. doi: 10.1371/journal.pone.0045725. Epub 2012 Sep 26.

43.

Tropical distal renal tubular acidosis: clinical and epidemiological studies in 78 patients.

Khositseth S, Bruce LJ, Walsh SB, Bawazir WM, Ogle GD, Unwin RJ, Thong MK, Sinha R, Choo KE, Chartapisak W, Kingwatanakul P, Sumboonnanonda A, Vasuvattakul S, Yenchitsomanus P, Wrong O.

QJM. 2012 Sep;105(9):861-77. doi: 10.1093/qjmed/hcs139. Review.

PMID:
22919024
44.

Back to the future: renal tubular acidosis then and now.

Unwin RJ.

QJM. 2012 Sep;105(9):915-6. doi: 10.1093/qjmed/hcs134. Epub 2012 Aug 1. No abstract available.

PMID:
22855286
45.

An intact kidney slice model to investigate vasa recta properties and function in situ.

Crawford C, Kennedy-Lydon T, Sprott C, Desai T, Sawbridge L, Munday J, Unwin RJ, Wildman SS, Peppiatt-Wildman CM.

Nephron Physiol. 2012;120(3):p17-31. doi: 10.1159/000339110. Epub 2012 Jul 20.

46.

P2 purinoceptors: Renal pathophysiology and therapeutic potential.

Booth JW, Tam FW, Unwin RJ.

Clin Nephrol. 2012 Aug;78(2):154-63. Review.

PMID:
22790461
47.

In memoriam: Oliver M. Wrong.

Scheinman SJ, Feehally J, Feest TG, Norden AG, Thakker RV, Unwin RJ.

Kidney Int. 2012 Jul;82(2):121-2. doi: 10.1038/ki.2012.183. No abstract available.

48.

Regulatory T cells participate in CD39-mediated protection from renal injury.

Wang YM, McRae JL, Robson SC, Cowan PJ, Zhang GY, Hu M, Polhill T, Wang Y, Zheng G, Wang Y, Lee VW, Unwin RJ, Harris DC, Dwyer KM, Alexander SI.

Eur J Immunol. 2012 Sep;42(9):2441-51. doi: 10.1002/eji.201242434.

49.

Pathogenesis of calcineurin inhibitor-induced hypertension.

Hoorn EJ, Walsh SB, McCormick JA, Zietse R, Unwin RJ, Ellison DH.

J Nephrol. 2012 May-Jun;25(3):269-75. doi: 10.5301/jn.5000174. Review.

50.

Is the albumin retrieval hypothesis a paradigm shift for nephrology?

Norden AG, Unwin RJ.

J Am Soc Nephrol. 2012 Apr;23(4):569-71. doi: 10.1681/ASN.2012020207. Epub 2012 Mar 15. No abstract available.

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