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Items: 14

1.

Author Correction: CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells.

Kim J, Hu Z, Cai L, Li K, Choi E, Faubert B, Bezwada D, Rodriguez-Canales J, Villalobos P, Lin YF, Ni M, Huffman KE, Girard L, Byers LA, Unsal-Kacmaz K, Peña CG, Heymach JV, Wauters E, Vansteenkiste J, Castrillon DH, Chen BPC, Wistuba I, Lambrechts D, Xu J, Minna JD, DeBerardinis RJ.

Nature. 2019 May;569(7756):E4. doi: 10.1038/s41586-019-1133-3.

PMID:
31043737
2.

Purine Nucleotide Availability Regulates mTORC1 Activity through the Rheb GTPase.

Emmanuel N, Ragunathan S, Shan Q, Wang F, Giannakou A, Huser N, Jin G, Myers J, Abraham RT, Unsal-Kacmaz K.

Cell Rep. 2017 Jun 27;19(13):2665-2680. doi: 10.1016/j.celrep.2017.05.043.

3.

CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells.

Kim J, Hu Z, Cai L, Li K, Choi E, Faubert B, Bezwada D, Rodriguez-Canales J, Villalobos P, Lin YF, Ni M, Huffman KE, Girard L, Byers LA, Unsal-Kacmaz K, Peña CG, Heymach JV, Wauters E, Vansteenkiste J, Castrillon DH, Chen BPC, Wistuba I, Lambrechts D, Xu J, Minna JD, DeBerardinis RJ.

Nature. 2017 Jun 1;546(7656):168-172. doi: 10.1038/nature22359. Epub 2017 May 24. Erratum in: Nature. 2019 May;569(7756):E4.

4.

Enzyme kinetics and distinct modulation of the protein kinase N family of kinases by lipid activators and small molecule inhibitors.

Falk MD, Liu W, Bolaños B, Unsal-Kacmaz K, Klippel A, Grant S, Brooun A, Timofeevski S.

Biosci Rep. 2014 Apr 1;34(2). pii: e00097. Print 2014 Apr 1.

5.

Blocking lactate export by inhibiting the Myc target MCT1 Disables glycolysis and glutathione synthesis.

Doherty JR, Yang C, Scott KE, Cameron MD, Fallahi M, Li W, Hall MA, Amelio AL, Mishra JK, Li F, Tortosa M, Genau HM, Rounbehler RJ, Lu Y, Dang CV, Kumar KG, Butler AA, Bannister TD, Hooper AT, Unsal-Kacmaz K, Roush WR, Cleveland JL.

Cancer Res. 2014 Feb 1;74(3):908-20. doi: 10.1158/0008-5472.CAN-13-2034. Epub 2013 Nov 27.

6.

The interaction of PKN3 with RhoC promotes malignant growth.

Unsal-Kacmaz K, Ragunathan S, Rosfjord E, Dann S, Upeslacis E, Grillo M, Hernandez R, Mack F, Klippel A.

Mol Oncol. 2012 Jun;6(3):284-98. doi: 10.1016/j.molonc.2011.12.001. Epub 2011 Dec 28.

7.

Tipin-replication protein A interaction mediates Chk1 phosphorylation by ATR in response to genotoxic stress.

Kemp MG, Akan Z, Yilmaz S, Grillo M, Smith-Roe SL, Kang TH, Cordeiro-Stone M, Kaufmann WK, Abraham RT, Sancar A, Unsal-Kaçmaz K.

J Biol Chem. 2010 May 28;285(22):16562-71. doi: 10.1074/jbc.M110.110304. Epub 2010 Mar 15.

8.

Ubiquitylation of proliferating cell nuclear antigen and recruitment of human DNA polymerase eta.

Nikolaishvili-Feinberg N, Jenkins GS, Nevis KR, Staus DP, Scarlett CO, Unsal-Kaçmaz K, Kaufmann WK, Cordeiro-Stone M.

Biochemistry. 2008 Apr 1;47(13):4141-50. doi: 10.1021/bi702329h. Epub 2008 Mar 6.

PMID:
18321066
9.

The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement.

Unsal-Kaçmaz K, Chastain PD, Qu PP, Minoo P, Cordeiro-Stone M, Sancar A, Kaufmann WK.

Mol Cell Biol. 2007 Apr;27(8):3131-42. Epub 2007 Feb 12.

10.

Cdc7-Dbf4 and the human S checkpoint response to UVC.

Heffernan TP, Unsal-Kaçmaz K, Heinloth AN, Simpson DA, Paules RS, Sancar A, Cordeiro-Stone M, Kaufmann WK.

J Biol Chem. 2007 Mar 30;282(13):9458-68. Epub 2007 Feb 2.

11.

Coupling of human circadian and cell cycles by the timeless protein.

Unsal-Kaçmaz K, Mullen TE, Kaufmann WK, Sancar A.

Mol Cell Biol. 2005 Apr;25(8):3109-16.

12.

Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints.

Sancar A, Lindsey-Boltz LA, Unsal-Kaçmaz K, Linn S.

Annu Rev Biochem. 2004;73:39-85. Review.

PMID:
15189136
13.
14.

Preferential binding of ATR protein to UV-damaged DNA.

Unsal-Kaçmaz K, Makhov AM, Griffith JD, Sancar A.

Proc Natl Acad Sci U S A. 2002 May 14;99(10):6673-8.

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