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Truncation limits of patient-based real-time quality control: a new model derived from between-subject biological variations.

Coşkun A, Çavuşoğlu C, Serteser M, Serdar M, Kilercik M, Aksungar F, Ünsal İ.

Clin Chem Lab Med. 2020 Mar 13. pii: /j/cclm.ahead-of-print/cclm-2020-0111/cclm-2020-0111.xml. doi: 10.1515/cclm-2020-0111. [Epub ahead of print] No abstract available.


Serum cortisol level after low dose dexamethasone suppression test may be predictive for diabetes mellitus and hypertension presence in obese patients: A retrospective study.

Hepsen S, Sencar E, Sakiz D, Akhanli P, Ucan B, Unsal I, Ozbek M, Cakal E.

Diabetes Res Clin Pract. 2020 Mar;161:108081. doi: 10.1016/j.diabres.2020.108081. Epub 2020 Feb 15.


An Evaluation of the Results of the Steroid and Non-steroidal Anti-inflammatory Drug Treatments in Subacute Thyroiditis in relation to Persistent Hypothyroidism and Recurrence.

Sencar ME, Calapkulu M, Sakiz D, Hepsen S, Kus A, Akhanli P, Unsal IO, Kizilgul M, Ucan B, Ozbek M, Cakal E.

Sci Rep. 2019 Nov 15;9(1):16899. doi: 10.1038/s41598-019-53475-w.


Coexistence of Type-1 Diabetes Mellitus and Papillary Thyroid Carcinoma.

Calapkulu M, Sencar ME, Duger H, Bayram SM, Unsal IO, Cakal E, Ozbek M.

Curr Diabetes Rev. 2019 Nov 3. doi: 10.2174/1573399815666191104114551. [Epub ahead of print]


Serum Vitamin D Level Does not Affect The Sensitivity of Parathyroid Adenoma Localization Tests.

Sencar ME, Sakiz D, Unsal IO, Hepsen S, Calapkulu M, Gumus P, Ucan B, Ozbek M, Cakal E.

Sci Rep. 2019 Aug 19;9(1):12035. doi: 10.1038/s41598-019-48536-z.


An Assessment of HbA1c in Diabetes Mellitus and Pre-diabetes Diagnosis: a Multi-centered Data Mining Study.

Serdar MA, Serteser M, Ucal Y, Karpuzoglu HF, Aksungar FB, Coskun A, Kilercik M, Ünsal İ, Özpınar A.

Appl Biochem Biotechnol. 2020 Jan;190(1):44-56. doi: 10.1007/s12010-019-03080-4. Epub 2019 Jul 13.


The short story of the long-term Sigma metric: shift cannot be treated as a linear parameter.

Coskun A, Serteser M, Ünsal I.

Clin Chem Lab Med. 2019 Aug 27;57(9):e211-e213. doi: 10.1515/cclm-2018-1139. No abstract available.


A Simple Method for Quantification of Five Urinary Porphyrins, Porphobilinogen and 5-Aminolevulinic Acid, Using Liquid Chromatography Tandem Mass Spectrometry.

Dogan O, Serdar MA, Murat K, Sonmez C, İspir E, Serteser M, Unsal I.

Indian J Clin Biochem. 2019 Jan;34(1):82-88. doi: 10.1007/s12291-017-0716-8. Epub 2017 Nov 10.


Sigma metric revisited: True known mistakes.

Coskun A, Serteser M, Ünsal I.

Biochem Med (Zagreb). 2019 Feb 15;29(1):010902. doi: 10.11613/BM.2019.010902. Epub 2018 Dec 15.


Exposure to Perchlorate in Lactating Women and Its Associations With Newborn Thyroid Stimulating Hormone.

Ucal Y, Sahin ON, Serdar M, Blount B, Kumru P, Muhcu M, Eroglu M, Akin-Levi C, Keles ZZY, Turam C, Valentin-Blasini L, Morel-Espinosa M, Serteser M, Unsal I, Ozpinar A.

Front Endocrinol (Lausanne). 2018 Jul 3;9:348. doi: 10.3389/fendo.2018.00348. eCollection 2018.


The EuBIVAS: Within- and Between-Subject Biological Variation Data for Electrolytes, Lipids, Urea, Uric Acid, Total Protein, Total Bilirubin, Direct Bilirubin, and Glucose.

Aarsand AK, Díaz-Garzón J, Fernandez-Calle P, Guerra E, Locatelli M, Bartlett WA, Sandberg S, Røraas T, Ceriotti F, Sølvik UØ, Sverresdotter Sylte M, Coşkun A, Serteser M, Unsal I, Tosato F, Plebani M, Jonker N, Barla G, Carobene A; European Federation of Clinical Chemistry and Laboratory Medicine Working Group on Biological Variation.

Clin Chem. 2018 Sep;64(9):1380-1393. doi: 10.1373/clinchem.2018.288415. Epub 2018 Jun 25.


The assessment of thyroid autoantibody levels in euthyroid patients with polycystic ovary syndrome

Hepşen S, Karaköse M, Çakal E, Öztekin S, Ünsal İ, Akhanlı P, Uçan B, Özbek M.

J Turk Ger Gynecol Assoc. 2018 Nov 15;19(4):215-219. doi: 10.4274/jtgga.2018.0001. Epub 2018 Apr 27.


Within-subject and between-subject biological variation estimates of 21 hematological parameters in 30 healthy subjects.

Coşkun A, Carobene A, Kilercik M, Serteser M, Sandberg S, Aarsand AK, Fernandez-Calle P, Jonker N, Bartlett WA, Díaz-Garzón J, Huet S, Kızıltaş C, Dalgakıran I, Ugur E, Unsal I; European Biological Variation Study of the EFLM Working Group on Biological Variation.

Clin Chem Lab Med. 2018 Jul 26;56(8):1309-1318. doi: 10.1515/cclm-2017-1155.


Vitamin D levels and parathyroid hormone variations of children living in a subtropical climate: a data mining study.

Sahin ON, Serdar M, Serteser M, Unsal I, Ozpinar A.

Ital J Pediatr. 2018 Mar 21;44(1):40. doi: 10.1186/s13052-018-0479-8.


The effects of metformin in type 1 diabetes mellitus.

Beysel S, Unsal IO, Kizilgul M, Caliskan M, Ucan B, Cakal E.

BMC Endocr Disord. 2018 Jan 16;18(1):1. doi: 10.1186/s12902-017-0228-9.


Pregnancy-associated plasma protein-A (PAPP-A) levels in patients with severe allergic asthma are reduced by omalizumab.

Bulut I, Ozseker ZF, Coskun A, Serteser M, Unsal I.

J Asthma. 2018 Oct;55(10):1116-1121. doi: 10.1080/02770903.2017.1396471. Epub 2017 Dec 6.


The EuBIVAS Project: Within- and Between-Subject Biological Variation Data for Serum Creatinine Using Enzymatic and Alkaline Picrate Methods and Implications for Monitoring.

Carobene A, Marino I, Coşkun A, Serteser M, Unsal I, Guerra E, Bartlett WA, Sandberg S, Aarsand AK, Sylte MS, Røraas T, Sølvik UØ, Fernandez-Calle P, Díaz-Garzón J, Tosato F, Plebani M, Jonker N, Barla G, Ceriotti F; European Biological Variation Study of the EFLM Working Group on Biological Variation.

Clin Chem. 2017 Sep;63(9):1527-1536. doi: 10.1373/clinchem.2017.275115. Epub 2017 Jul 18.


Analysis of Changes in Parathyroid Hormone and 25 (OH) Vitamin D Levels with Respect to Age, Gender and Season: A Data Mining Study.

Serdar MA, Batu Can B, Kilercik M, Durer ZA, Aksungar FB, Serteser M, Coskun A, Ozpinar A, Unsal I.

J Med Biochem. 2017 Jan 25;36(1):73-83. doi: 10.1515/jomb-2017-0002. eCollection 2017 Jan.


Comparison of Intermittent Fasting Versus Caloric Restriction in Obese Subjects: A Two Year Follow-Up.

Aksungar FB, Sarıkaya M, Coskun A, Serteser M, Unsal I.

J Nutr Health Aging. 2017;21(6):681-685. doi: 10.1007/s12603-016-0786-y.


Biological Variation Estimates Obtained from 91 Healthy Study Participants for 9 Enzymes in Serum.

Carobene A, Røraas T, Sølvik UØ, Sylte MS, Sandberg S, Guerra E, Marino I, Jonker N, Barla G, Bartlett WA, Fernandez-Calle P, Díaz-Garzón J, Tosato F, Plebani M, Coşkun A, Serteser M, Unsal I, Ceriotti F; European Biological Variation Study of the EFLM Working Group on Biological Variation.

Clin Chem. 2017 Jun;63(6):1141-1150. doi: 10.1373/clinchem.2016.269811. Epub 2017 Apr 20.


Frequency of nodular goiter and autoimmune thyroid disease and association of these disorders with insulin resistance in polycystic ovary syndrome.

Karaköse M, Hepsen S, Çakal E, Saykı Arslan M, Tutal E, Akın Ş, Ünsal İ, Özbek M.

J Turk Ger Gynecol Assoc. 2017 Jun 1;18(2):85-89. doi: 10.4274/jtgga.2016.0217. Epub 2017 Feb 7.


Evaluation of the performance of INDEXOR® in the archive unit of a clinical laboratory: a step to Lean laboratory.

Coskun A, Serteser M, Altinayak R, Unsal I.

Clin Chem Lab Med. 2017 Mar 1;55(3):e62-e64. doi: 10.1515/cclm-2016-0427. No abstract available.


How can we evaluate differences between serial measurements on the same sample? A new approach based on within-subject biological variation.

Coskun A, Serteser M, Karpuzoglu HF, Unsal I.

Clin Chem Lab Med. 2017 Feb 1;55(2):e44-e46. doi: 10.1515/cclm-2016-0574. No abstract available.


Perchlorate Exposure Through Water and Milk in Istanbul.

Can O, Blount B, Valentin-Blasini L, Erdemgil Y, Uzunoglu D, Aksoy M, Coskun A, Serteser M, Unsal I, Ozpinar A.

Bull Environ Contam Toxicol. 2016 Sep;97(3):439-45. doi: 10.1007/s00128-016-1889-1. Epub 2016 Jul 19.


Sample collections from healthy volunteers for biological variation estimates' update: a new project undertaken by the Working Group on Biological Variation established by the European Federation of Clinical Chemistry and Laboratory Medicine.

Carobene A, Strollo M, Jonker N, Barla G, Bartlett WA, Sandberg S, Sylte MS, Røraas T, Sølvik UØ, Fernandez-Calle P, Díaz-Garzón J, Tosato F, Plebani M, Coşkun A, Serteser M, Unsal I, Ceriotti F; Biological Variation Working Group, European Federation of Clinical Chemistry and Laboratory Medicine.

Clin Chem Lab Med. 2016 Oct 1;54(10):1599-608. doi: 10.1515/cclm-2016-0035.


Z transformation is the gold standard for computing the sigma metric.

Coskun A, Serteser M, Serdar M, Aksungar F, Kilercik M, Unsal I.

Clin Biochem. 2016 Jun;49(9):732-733. doi: 10.1016/j.clinbiochem.2016.04.002. Epub 2016 Apr 11. No abstract available.


Visceral Obesity Mediates the Association Between Metabolic Syndrome and Obstructive Sleep Apnea Syndrome.

Bozkurt NC, Beysel S, Karbek B, Unsal İO, Cakir E, Delibasi T.

Metab Syndr Relat Disord. 2016 May;14(4):217-21. doi: 10.1089/met.2015.0086. Epub 2016 Mar 22.


Hepatitis C virus positive patient diagnosed after detection of atypical cryoglobulin.

Ongen B, Aksungar FB, Cicek B, Akyar I, Coskun A, Serteser M, Unsal I.

World J Clin Cases. 2016 Mar 16;4(3):81-7. doi: 10.12998/wjcc.v4.i3.81.


Perchlorate levels found in tap water collected from several cities in Turkey.

Erdemgil Y, Gözet T, Can Ö, Ünsal İ, Özpınar A.

Environ Monit Assess. 2016 Mar;188(3):158. doi: 10.1007/s10661-016-5161-2. Epub 2016 Feb 11.


Sigma metric or defects per million opportunities (DPMO): the performance of clinical laboratories should be evaluated by the Sigma metrics at decimal level with DPMOs.

Coskun A, Oosterhuis WP, Serteser M, Unsal I.

Clin Chem Lab Med. 2016 Aug 1;54(8):e217-9. doi: 10.1515/cclm-2015-1219. No abstract available.


A Simple and Easy Process for the Determination of Estimated Plasma Glucose Level in Patients Presenting to Hospital: An Example of Multicentric Data Mining.

Serdar MA, Koldaş M, Serteser M, Akın O, Sonmez C, Gülbahar O, Akbıyık F, Ünsal I.

J Lab Autom. 2016 Dec;21(6):794-798. Epub 2016 Jan 8.


Are Meteorological Parameters a Risk Factor for Pulmonary Embolism? A Retrospective Analysis of 530 Patients.

Anar C, İnal T, Erol S, Polat G, Ünsal İ, Ediboğlu Ö, Halilçolar H.

Balkan Med J. 2015 Jul;32(3):279-84. doi: 10.5152/balkanmedj.2015.15686. Epub 2015 Jul 1.


Hyperprolactinemia has no effect on plasma ghrelin levels in patients with prolactinoma.

Delibaşı T, Arslan MS, Çakal E, Şahin M, Topaloğlu O, Tutal E, Ünsal İÖ, Karbek B, Uçan B, Güngüneş A, Karaköse M, Çalışkan M, Demirci T, Tabur G, Özbek M.

J Turk Ger Gynecol Assoc. 2015 Jun 1;16(2):86-90. doi: 10.5152/jtgga.2015.15015. eCollection 2015.


Usefulness of the neutrophil-to-lymphocyte ratio to prediction of type 2 diabetes mellitus in morbid obesity.

Yilmaz H, Ucan B, Sayki M, Unsal I, Sahin M, Ozbek M, Delibasi T.

Diabetes Metab Syndr. 2015 Oct-Dec;9(4):299-304. doi: 10.1016/j.dsx.2014.04.009. Epub 2014 May 19.


Post-translational modifications of transthyretin affect the triiodonine-binding potential.

Henze A, Homann T, Serteser M, Can O, Sezgin O, Coskun A, Unsal I, Schweigert FJ, Ozpinar A.

J Cell Mol Med. 2015 Feb;19(2):359-70. doi: 10.1111/jcmm.12446. Epub 2014 Oct 14.


Comparison of therapeutic characteristics of islet cell transplantation simultaneous with pancreatic mesenchymal stem cell transplantation in rats with Type 1 diabetes mellitus.

Unsal IO, Ginis Z, Pinarli FA, Albayrak A, Cakal E, Sahin M, Delibasi T.

Stem Cell Rev Rep. 2015 Jun;11(3):526-32. doi: 10.1007/s12015-014-9563-7.


Elastography in the differential diagnosis of thyroid nodules.

Çakal E, Şahin M, Ünsal İÖ, Güngüneş A, Akkaymak E, Özkaya EÇ, Bozkurt NÇ, Özbek M, Delibaşı T.

Ultrason Imaging. 2015 Jul;37(3):251-7. doi: 10.1177/0161734614547542. Epub 2014 Aug 25.


Elastography in the differential diagnosis of thyroid nodules in Hashimoto thyroiditis.

Şahin M, Çakal E, Özbek M, Güngünes A, Arslan MS, Akkaymak ET, Uçan B, Ünsal IÖ, Bozkurt NÇ, Delibaşi T.

Med Oncol. 2014 Aug;31(8):97. doi: 10.1007/s12032-014-0097-2. Epub 2014 Jul 3.


Cushing's syndrome in type 2 diabetes patients with poor glycemic control.

Gungunes A, Sahin M, Demirci T, Ucan B, Cakir E, Arslan MS, Unsal IO, Karbek B, Calıskan M, Ozbek M, Cakal E, Delibasi T.

Endocrine. 2014 Dec;47(3):895-900. doi: 10.1007/s12020-014-0260-8. Epub 2014 Apr 17.


The prognostic value of D-dimer in lung cancer.

İnal T, Anar C, Polat G, Ünsal İ, Halilçolar H.

Clin Respir J. 2015 Jul;9(3):305-13. doi: 10.1111/crj.12144. Epub 2014 Jun 16.


Biological variations of ADAMTS13 and von Willebrand factor in human adults.

Kilercik M, Coskun A, Serteser M, Inan D, Unsal I.

Biochem Med (Zagreb). 2014 Feb 15;24(1):138-45. doi: 10.11613/BM.2014.015. eCollection 2014.


Iodine status in Turkish populations and exposure to iodide uptake inhibitors.

Ozpinar A, Kelestimur F, Songur Y, Can O, Valentin L, Caldwell K, Arikan E, Unsal I, Serteser M, Inal T, Erdemgil Y, Coskun A, Bakirci N, Sezgin O, Blount B.

PLoS One. 2014 Feb 5;9(2):e88206. doi: 10.1371/journal.pone.0088206. eCollection 2014.


Association between serum pregnancy-associated plasma protein-A and bicarbonate in hemodialysis patients.

Bicik Z, Coskun A, Serteser M, Bulur A, Mese M, Unsal I.

J Clin Lab Anal. 2014 Mar;28(2):114-7. doi: 10.1002/jcla.21653. Epub 2014 Jan 6.


A triclonal gammopathy in a relapsing multiple myeloma patient, detected by immunosubtraction method.

Aksungar FB, Ayer M, Serteser M, Coskun A, Unsal I.

Ann Clin Biochem. 2014 Sep;51(Pt 5):606-10. doi: 10.1177/0004563213512801. Epub 2013 Dec 20.


Cardiovascular risk factors, carotid artery intima media thickness, and HSCRP levels in patients with impaired glucose metabolism.

Karbek B, Cakal E, Cakir E, Bozkurt N, Unsal I, Sahin M, Delibaşi T.

Minerva Endocrinol. 2013 Sep;38(3):297-304.


Vitamin D3 levels and insulin resistance in papillary thyroid cancer patients.

Sahin M, Uçan B, Giniş Z, Topaloğlu O, Güngüneş A, Bozkurt NÇ, Arslan MS, Ünsal İÖ, Akkaymak ET, Demirci T, Karaköse M, Çalışkan M, Çakal E, Özbek M, Delibaşı T.

Med Oncol. 2013;30(2):589. doi: 10.1007/s12032-013-0589-5. Epub 2013 May 5.


A comparison between turbidimetric inhibition immunoassay and capillary electrophoresis in glycated hemoglobin (HbA1c) measurement.

Aksungar FB, Serteser M, Coşkun A, Ünsal İ.

Clin Chem Lab Med. 2013 Aug;51(8):e191-3. doi: 10.1515/cclm-2013-0033. No abstract available.


The relationship between LH and thyroid volume in patients with PCOS.

Cakir E, Sahin M, Topaloglu O, Colak NB, Karbek B, Gungunes A, Arslan MS, Unsal IO, Tutal E, Ucan B, Delibasi T.

J Ovarian Res. 2012 Dec 11;5(1):43. doi: 10.1186/1757-2215-5-43.


Reference interval of pregnancy-associated plasma protein-a in healthy men and non-pregnant women.

Coskun A, Serteser M, Duran S, Inal TC, Erdogan BE, Ozpinar A, Can O, Unsal I.

J Cardiol. 2013 Feb;61(2):128-31. doi: 10.1016/j.jjcc.2012.09.007. Epub 2012 Nov 16.


Parathyroid adenoma screening efficacies of different imaging tools and factors affecting the success rates.

Cakal E, Cakir E, Dilli A, Colak N, Unsal I, Aslan MS, Karbek B, Ozbek M, Kilic M, Delibasi T, Sahin M.

Clin Imaging. 2012 Nov-Dec;36(6):688-94. doi: 10.1016/j.clinimag.2012.01.038. Epub 2012 Jun 8.


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