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Items: 44

1.

CDCA7 and HELLS mutations undermine nonhomologous end joining in centromeric instability syndrome.

Unoki M, Funabiki H, Velasco G, Francastel C, Sasaki H.

J Clin Invest. 2019 Jan 2;129(1):78-92. doi: 10.1172/JCI99751. Epub 2018 Nov 19.

2.

Accurate estimation of 5-methylcytosine in mammalian mitochondrial DNA.

Matsuda S, Yasukawa T, Sakaguchi Y, Ichiyanagi K, Unoki M, Gotoh K, Fukuda K, Sasaki H, Suzuki T, Kang D.

Sci Rep. 2018 Apr 11;8(1):5801. doi: 10.1038/s41598-018-24251-z.

3.

Role of UHRF1 in de novo DNA methylation in oocytes and maintenance methylation in preimplantation embryos.

Maenohara S, Unoki M, Toh H, Ohishi H, Sharif J, Koseki H, Sasaki H.

PLoS Genet. 2017 Oct 4;13(10):e1007042. doi: 10.1371/journal.pgen.1007042. eCollection 2017 Oct.

4.

Corrigendum: Mutations in CDCA7 and HELLS cause immunodeficiency-centromeric instability-facial anomalies syndrome.

Thijssen PE, Ito Y, Grillo G, Wang J, Velasco G, Nitta H, Unoki M, Yoshihara M, Suyama M, Sun Y, Lemmers RJ, de Greef JC, Gennery A, Picco P, Kloeckener-Gruissem B, Güngör T, Reisli I, Picard C, Kebaili K, Roquelaure B, Iwai T, Kondo I, Kubota T, van Ostaijen-Ten Dam MM, van Tol MJ, Weemaes C, Francastel C, van der Maarel SM, Sasaki H.

Nat Commun. 2016 Jun 22;7:12003. doi: 10.1038/ncomms12003. No abstract available.

5.

Mutations in CDCA7 and HELLS cause immunodeficiency-centromeric instability-facial anomalies syndrome.

Thijssen PE, Ito Y, Grillo G, Wang J, Velasco G, Nitta H, Unoki M, Yoshihara M, Suyama M, Sun Y, Lemmers RJ, de Greef JC, Gennery A, Picco P, Kloeckener-Gruissem B, Güngör T, Reisli I, Picard C, Kebaili K, Roquelaure B, Iwai T, Kondo I, Kubota T, van Ostaijen-Ten Dam MM, van Tol MJ, Weemaes C, Francastel C, van der Maarel SM, Sasaki H.

Nat Commun. 2015 Jul 28;6:7870. doi: 10.1038/ncomms8870. Erratum in: Nat Commun. 2016 Jun 22;7:12003.

6.

Three novel ZBTB24 mutations identified in Japanese and Cape Verdean type 2 ICF syndrome patients.

Nitta H, Unoki M, Ichiyanagi K, Kosho T, Shigemura T, Takahashi H, Velasco G, Francastel C, Picard C, Kubota T, Sasaki H.

J Hum Genet. 2013 Jul;58(7):455-60. doi: 10.1038/jhg.2013.56. Epub 2013 Jun 6.

PMID:
23739126
7.

Lysyl 5-hydroxylation, a novel histone modification, by Jumonji domain containing 6 (JMJD6).

Unoki M, Masuda A, Dohmae N, Arita K, Yoshimatsu M, Iwai Y, Fukui Y, Ueda K, Hamamoto R, Shirakawa M, Sasaki H, Nakamura Y.

J Biol Chem. 2013 Mar 1;288(9):6053-62. doi: 10.1074/jbc.M112.433284. Epub 2013 Jan 9.

8.

UHRF1 expression is upregulated and associated with cellular proliferation in colorectal cancer.

Kofunato Y, Kumamoto K, Saitou K, Hayase S, Okayama H, Miyamoto K, Sato Y, Katakura K, Nakamura I, Ohki S, Koyama Y, Unoki M, Takenoshita S.

Oncol Rep. 2012 Dec;28(6):1997-2002. doi: 10.3892/or.2012.2064. Epub 2012 Sep 27.

PMID:
23023523
9.

Recognition of modification status on a histone H3 tail by linked histone reader modules of the epigenetic regulator UHRF1.

Arita K, Isogai S, Oda T, Unoki M, Sugita K, Sekiyama N, Kuwata K, Hamamoto R, Tochio H, Sato M, Ariyoshi M, Shirakawa M.

Proc Natl Acad Sci U S A. 2012 Aug 7;109(32):12950-5. doi: 10.1073/pnas.1203701109. Epub 2012 Jul 25.

10.

NIRF/UHRF2 occupies a central position in the cell cycle network and allows coupling with the epigenetic landscape.

Mori T, Ikeda DD, Yamaguchi Y, Unoki M; NIRF Project.

FEBS Lett. 2012 Jun 4;586(11):1570-83. doi: 10.1016/j.febslet.2012.04.038. Epub 2012 Apr 30. Review.

11.

Demethylation of RB regulator MYPT1 by histone demethylase LSD1 promotes cell cycle progression in cancer cells.

Cho HS, Suzuki T, Dohmae N, Hayami S, Unoki M, Yoshimatsu M, Toyokawa G, Takawa M, Chen T, Kurash JK, Field HI, Ponder BA, Nakamura Y, Hamamoto R.

Cancer Res. 2011 Feb 1;71(3):655-60. doi: 10.1158/0008-5472.CAN-10-2446. Epub 2010 Nov 29.

12.

Current and potential anticancer drugs targeting members of the UHRF1 complex including epigenetic modifiers.

Unoki M.

Recent Pat Anticancer Drug Discov. 2011 Jan;6(1):116-30. Review.

PMID:
21110828
13.

UHRF1 is a novel diagnostic marker of lung cancer.

Unoki M, Daigo Y, Koinuma J, Tsuchiya E, Hamamoto R, Nakamura Y.

Br J Cancer. 2010 Jul 13;103(2):217-22. doi: 10.1038/sj.bjc.6605717. Epub 2010 Jun 1.

14.

Dysregulation of PRMT1 and PRMT6, Type I arginine methyltransferases, is involved in various types of human cancers.

Yoshimatsu M, Toyokawa G, Hayami S, Unoki M, Tsunoda T, Field HI, Kelly JD, Neal DE, Maehara Y, Ponder BA, Nakamura Y, Hamamoto R.

Int J Cancer. 2011 Feb 1;128(3):562-73. doi: 10.1002/ijc.25366.

15.

Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers.

Hayami S, Kelly JD, Cho HS, Yoshimatsu M, Unoki M, Tsunoda T, Field HI, Neal DE, Yamaue H, Ponder BA, Nakamura Y, Hamamoto R.

Int J Cancer. 2011 Feb 1;128(3):574-86. doi: 10.1002/ijc.25349.

16.

Overexpression of the JmjC histone demethylase KDM5B in human carcinogenesis: involvement in the proliferation of cancer cells through the E2F/RB pathway.

Hayami S, Yoshimatsu M, Veerakumarasivam A, Unoki M, Iwai Y, Tsunoda T, Field HI, Kelly JD, Neal DE, Yamaue H, Ponder BA, Nakamura Y, Hamamoto R.

Mol Cancer. 2010 Mar 13;9:59. doi: 10.1186/1476-4598-9-59.

17.

Drug discovery targeting epigenetic codes: the great potential of UHRF1, which links DNA methylation and histone modifications, as a drug target in cancers and toxoplasmosis.

Unoki M, Brunet J, Mousli M.

Biochem Pharmacol. 2009 Nov 15;78(10):1279-88. doi: 10.1016/j.bcp.2009.05.035. Epub 2009 Jun 6. Review.

PMID:
19501055
18.

UHRF1 is a novel molecular marker for diagnosis and the prognosis of bladder cancer.

Unoki M, Kelly JD, Neal DE, Ponder BA, Nakamura Y, Hamamoto R.

Br J Cancer. 2009 Jul 7;101(1):98-105. doi: 10.1038/sj.bjc.6605123. Epub 2009 Jun 2.

19.

ING proteins as potential anticancer drug targets.

Unoki M, Kumamoto K, Harris CC.

Curr Drug Targets. 2009 May;10(5):442-54. Review.

20.

ING2 is upregulated in colon cancer and increases invasion by enhanced MMP13 expression.

Kumamoto K, Fujita K, Kurotani R, Saito M, Unoki M, Hagiwara N, Shiga H, Bowman ED, Yanaihara N, Okamura S, Nagashima M, Miyamoto K, Takenoshita S, Yokota J, Harris CC.

Int J Cancer. 2009 Sep 15;125(6):1306-15. doi: 10.1002/ijc.24437.

21.

Reviewing the current classification of inhibitor of growth family proteins.

Unoki M, Kumamoto K, Takenoshita S, Harris CC.

Cancer Sci. 2009 Jul;100(7):1173-9. doi: 10.1111/j.1349-7006.2009.01183.x. Epub 2009 Apr 28. Review.

22.

A novel ING2 isoform, ING2b, synergizes with ING2a to prevent cell cycle arrest and apoptosis.

Unoki M, Kumamoto K, Robles AI, Shen JC, Zheng ZM, Harris CC.

FEBS Lett. 2008 Nov 26;582(28):3868-74. doi: 10.1016/j.febslet.2008.10.024. Epub 2008 Oct 23.

23.

A concern regarding the current confusion with the human homolog of mouse Np95, ICBP90/UHRF1.

Unoki M, Bronner C, Mousli M.

Radiat Res. 2008 Feb;169(2):240-4. doi: 10.1667/RR1209.1.

PMID:
18220474
24.

Toxoplasma gondii exploits UHRF1 and induces host cell cycle arrest at G2 to enable its proliferation.

Brunet J, Pfaff AW, Abidi A, Unoki M, Nakamura Y, Guinard M, Klein JP, Candolfi E, Mousli M.

Cell Microbiol. 2008 Apr;10(4):908-20. Epub 2007 Nov 14.

PMID:
18005238
25.

Inhibitor of growth 4 suppresses cell spreading and cell migration by interacting with a novel binding partner, liprin alpha1.

Shen JC, Unoki M, Ythier D, Duperray A, Varticovski L, Kumamoto K, Pedeux R, Harris CC.

Cancer Res. 2007 Mar 15;67(6):2552-8.

26.

Comparison of the roex and gammachirp filters as representations of the auditory filter.

Unoki M, Irino T, Glasberg B, Moore BC, Patterson RD.

J Acoust Soc Am. 2006 Sep;120(3):1474-92.

27.

Novel splice variants of ING4 and their possible roles in the regulation of cell growth and motility.

Unoki M, Shen JC, Zheng ZM, Harris CC.

J Biol Chem. 2006 Nov 10;281(45):34677-86. Epub 2006 Sep 13.

28.

ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain.

Unoki M, Nishidate T, Nakamura Y.

Oncogene. 2004 Oct 7;23(46):7601-10.

PMID:
15361834
29.

Methylation at CpG islands in intron 1 of EGR2 confers enhancer-like activity.

Unoki M, Nakamura Y.

FEBS Lett. 2003 Nov 6;554(1-2):67-72.

30.

Extending the domain of center frequencies for the compressive gammachirp auditory filter.

Patterson RD, Unoki M, Irino T.

J Acoust Soc Am. 2003 Sep;114(3):1529-42.

PMID:
14514206
31.

Identification of a novel human gene, ZFP91, involved in acute myelogenous leukemia.

Unoki M, Okutsu J, Nakamura Y.

Int J Oncol. 2003 Jun;22(6):1217-23.

PMID:
12738986
32.
33.
34.

Growth and gene expression profile analyses of endometrial cancer cells expressing exogenous PTEN.

Matsushima-Nishiu M, Unoki M, Ono K, Tsunoda T, Minaguchi T, Kuramoto H, Nishida M, Satoh T, Tanaka T, Nakamura Y.

Cancer Res. 2001 May 1;61(9):3741-9.

35.
36.

Amino-acid substitutions in the IKAP gene product significantly increase risk for bronchial asthma in children.

Takeoka S, Unoki M, Onouchi Y, Doi S, Fujiwara H, Miyatake A, Fujita K, Inoue I, Nakamura Y, Tamari M.

J Hum Genet. 2001;46(2):57-63.

PMID:
11281413
37.

Association between a single-nucleotide polymorphism in the promoter of the human interleukin-3 gene and rheumatoid arthritis in Japanese patients, and maximum-likelihood estimation of combinatorial effect that two genetic loci have on susceptibility to the disease.

Yamada R, Tanaka T, Unoki M, Nagai T, Sawada T, Ohnishi Y, Tsunoda T, Yukioka M, Maeda A, Suzuki K, Tateishi H, Ochi T, Nakamura Y, Yamamoto K.

Am J Hum Genet. 2001 Mar;68(3):674-85. Epub 2001 Feb 14.

38.

Association studies of 33 single nucleotide polymorphisms (SNPs) in 29 candidate genes for bronchial asthma: positive association a T924C polymorphism in the thromboxane A2 receptor gene.

Unoki M, Furuta S, Onouchi Y, Watanabe O, Doi S, Fujiwara H, Miyatake A, Fujita K, Tamari M, Nakamura Y.

Hum Genet. 2000 Apr;106(4):440-6.

PMID:
10830912
39.

[Equilibrium test].

Yabe T, Unoki M.

Nihon Rinsho. 1997 Mar;55 Suppl 1:473-9. Review. Japanese. No abstract available.

PMID:
9097654
40.

Enzyme immunosensors based on electropolymerized polytyramine modified electrodes.

Tsuji I, Eguchi H, Yasukouchi K, Unoki M, Taniguchi I.

Biosens Bioelectron. 1990;5(2):87-101.

PMID:
2184844
41.

Epitope mapping of human thyrotropin.

Endo Y, Miyai K, Iijima Y, Nakajima T, Eda Y, Fujita H, Unoki M.

Acta Endocrinol (Copenh). 1989 Feb;120(2):201-9.

PMID:
2464890
42.

Highly specific enzyme immunoassay for the beta-subunit of human thyrotropin with use of monoclonal antibodies.

Iijima Y, Endo Y, Hata N, Fujita H, Unoki M, Miyal K.

Clin Chem. 1988 Jan;34(1):98-102.

43.

Plasma phosphorus, alkaline phosphatase and calcium levels, and bone mass of the second metacarpal in women: relation to body weight.

Kono S, Iiguma T, Takenaka S, Unoki M.

Asia Oceania J Obstet Gynaecol. 1985 Dec;11(4):563-71. No abstract available.

PMID:
3833158
44.

[SYNTHESIS OF O-ACYLTHIAMINES].

UNOKI M, MITSUGI T.

Yakugaku Zasshi. 1964 Aug;84:780-3. Japanese. No abstract available.

PMID:
14236249

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