Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 549

1.

The cholesterol, fatty acid and triglyceride synthesis pathways regulated by site 1 protease (S1P) are required for efficient replication of severe fever with thrombocytopenia syndrome virus.

Urata S, Uno Y, Kurosaki Y, Yasuda J.

Biochem Biophys Res Commun. 2018 Jun 14. pii: S0006-291X(18)31365-2. doi: 10.1016/j.bbrc.2018.06.053. [Epub ahead of print]

PMID:
29906459
2.

Limited Expression of Functional Cytochrome P450 2C Subtypes in the Liver and Small Intestine of Domestic Cats.

Ono Y, Sugiyama S, Matsushita M, Kitazawa T, Amano T, Uno Y, Ikushiro S, Teraoka H.

Xenobiotica. 2018 May 31:1-36. doi: 10.1080/00498254.2018.1483543. [Epub ahead of print]

PMID:
29848168
3.

"Latent Gastric Cancer" after Eradicating Helicobacter pylori.

Uno Y.

Gut Liver. 2018 May 15;12(3):367-368. doi: 10.5009/gnl17463. No abstract available.

4.

CLICK: one-step generation of conditional knockout mice.

Miyasaka Y, Uno Y, Yoshimi K, Kunihiro Y, Yoshimura T, Tanaka T, Ishikubo H, Hiraoka Y, Takemoto N, Tanaka T, Ooguchi Y, Skehel P, Aida T, Takeda J, Mashimo T.

BMC Genomics. 2018 May 2;19(1):318. doi: 10.1186/s12864-018-4713-y.

5.

[Effective Techniques to Reduce Radiation Exposure to Medical Staff during Assist of X-ray Computed Tomography Examination].

Miyajima R, Fujibuchi T, Miyachi Y, Tateishi S, Uno Y, Amakawa K, Ohura H, Orita S.

Nihon Hoshasen Gijutsu Gakkai Zasshi. 2018;74(4):326-334. doi: 10.6009/jjrt.2018_JSRT_74.4.326. Japanese.

6.

Colonic transit time and pressure based on Bernoulli's principle.

Uno Y.

Clin Exp Gastroenterol. 2018 Apr 5;11:153-163. doi: 10.2147/CEG.S153676. eCollection 2018.

7.

Importance of cynomolgus monkeys in development of monoclonal antibody drugs.

Iwasaki K, Uno Y, Uto M, Yamazaki H.

Drug Metab Pharmacokinet. 2018 Mar 20. pii: S1347-4367(17)30074-5. doi: 10.1016/j.dmpk.2018.02.003. [Epub ahead of print] Review.

PMID:
29655914
8.

In vivo and in vitro diclofenac 5-hydroxylation mediated primarily by cytochrome P450 3A enzymes in common marmoset livers genotyped for P450 2C19 variants.

Nakanishi K, Uehara S, Kusama T, Inoue T, Shimura K, Kamiya Y, Murayama N, Shimizu M, Uno Y, Sasaki E, Yamazaki H.

Biochem Pharmacol. 2018 Jun;152:272-278. doi: 10.1016/j.bcp.2018.04.002. Epub 2018 Apr 5.

PMID:
29626440
9.

Development and validation of a scoring system for prediction of insulin requirement for optimal control of blood glucose during glucocorticoid treatments.

Kawashima M, Taguchi K, Kitada Y, Yamauchi M, Ikeda T, Kajita K, Murakami D, Okada H, Uno Y, Mori I, Ishizuka T, Morita H.

Diabetes Res Clin Pract. 2018 Jun;140:72-80. doi: 10.1016/j.diabres.2018.03.043. Epub 2018 Apr 3.

PMID:
29621562
10.

Molecular characterization and polymorphisms of butyrylcholinesterase in cynomolgus macaques.

Uno Y, Uehara S, Mahadhi HMD, Ohura K, Hosokawa M, Imai T.

J Med Primatol. 2018 Jun;47(3):185-191. doi: 10.1111/jmp.12342. Epub 2018 Mar 24.

PMID:
29573432
11.

Correlation between the results of in vitro and in vivo chromosomal damage tests in consideration of exposure levels of test chemicals.

Yamamura E, Aruga C, Muto S, Baba N, Uno Y.

Genes Environ. 2018 Mar 6;40:6. doi: 10.1186/s41021-018-0094-3. eCollection 2018.

12.

Polymorphisms of cytochrome P450 2B6 (CYP2B6) in cynomolgus and rhesus macaques.

Uno Y, Uehara S, Yamazaki H.

J Med Primatol. 2018 Feb 22. doi: 10.1111/jmp.12336. [Epub ahead of print]

PMID:
29468688
13.

Radiation-induced enteropathy - how a low-FODMAP diet might help.

Uno Y.

Scand J Gastroenterol. 2018 Mar;53(3):377-378. doi: 10.1080/00365521.2018.1437929. Epub 2018 Feb 12. No abstract available.

PMID:
29433349
14.

Marmoset cytochrome P450 2B6, a propofol hydroxylase expressed in liver.

Oshio T, Uehara S, Uno Y, Inoue T, Sasaki E, Yamazaki H.

Xenobiotica. 2018 Feb 21:1-5. doi: 10.1080/00498254.2018.1439204. [Epub ahead of print]

PMID:
29417863
15.

Analysis of carboxylesterase 2 transcript variants in cynomolgus macaque liver.

Uno Y, Igawa Y, Tanaka M, Ohura K, Hosokawa M, Imai T.

Xenobiotica. 2018 Apr 27:1-9. doi: 10.1080/00498254.2018.1435927. [Epub ahead of print]

PMID:
29384423
16.

Integrative Analyses of De Novo Mutations Provide Deeper Biological Insights into Autism Spectrum Disorder.

Takata A, Miyake N, Tsurusaki Y, Fukai R, Miyatake S, Koshimizu E, Kushima I, Okada T, Morikawa M, Uno Y, Ishizuka K, Nakamura K, Tsujii M, Yoshikawa T, Toyota T, Okamoto N, Hiraki Y, Hashimoto R, Yasuda Y, Saitoh S, Ohashi K, Sakai Y, Ohga S, Hara T, Kato M, Nakamura K, Ito A, Seiwa C, Shirahata E, Osaka H, Matsumoto A, Takeshita S, Tohyama J, Saikusa T, Matsuishi T, Nakamura T, Tsuboi T, Kato T, Suzuki T, Saitsu H, Nakashima M, Mizuguchi T, Tanaka F, Mori N, Ozaki N, Matsumoto N.

Cell Rep. 2018 Jan 16;22(3):734-747. doi: 10.1016/j.celrep.2017.12.074.

17.

Rare loss of function mutations in N-methyl-D-aspartate glutamate receptors and their contributions to schizophrenia susceptibility.

Yu Y, Lin Y, Takasaki Y, Wang C, Kimura H, Xing J, Ishizuka K, Toyama M, Kushima I, Mori D, Arioka Y, Uno Y, Shiino T, Nakamura Y, Okada T, Morikawa M, Ikeda M, Iwata N, Okahisa Y, Takaki M, Sakamoto S, Someya T, Egawa J, Usami M, Kodaira M, Yoshimi A, Oya-Ito T, Aleksic B, Ohno K, Ozaki N.

Transl Psychiatry. 2018 Jan 10;8(1):12. doi: 10.1038/s41398-017-0061-y.

18.

Letter: irritable bowel syndrome-how a low-FODMAP diet or yoga might help.

Uno Y.

Aliment Pharmacol Ther. 2018 Feb;47(3):444-445. doi: 10.1111/apt.14433. No abstract available.

PMID:
29314135
19.

Astrocytes in primary cultures express serine racemase, synthesize d-serine and acquire A1 reactive astrocyte features.

Li S, Uno Y, Rudolph U, Cobb J, Liu J, Anderson T, Levy D, Balu DT, Coyle JT.

Biochem Pharmacol. 2018 May;151:245-251. doi: 10.1016/j.bcp.2017.12.023. Epub 2018 Jan 3.

PMID:
29305854
20.

Genetic polymorphisms of drug-metabolizing cytochrome P450 enzymes in cynomolgus and rhesus monkeys and common marmosets in preclinical studies for humans.

Uno Y, Uehara S, Yamazaki H.

Biochem Pharmacol. 2018 Jul;153:184-195. doi: 10.1016/j.bcp.2017.12.015. Epub 2017 Dec 23. Review.

PMID:
29277691
21.

Analysis of major paralogs encoding the Fra a 1 allergen based on their organ-specificity in Fragaria × ananassa.

Ishibashi M, Nabe T, Nitta Y, Tsuruta H, Iduhara M, Uno Y.

Plant Cell Rep. 2018 Mar;37(3):411-424. doi: 10.1007/s00299-017-2237-6. Epub 2017 Nov 25.

PMID:
29177844
22.

Assessment of multiple cytochrome P450 activities in metabolically inactivated human liver microsomes and roles of P450 2C isoforms in reaction phenotyping studies.

Murayama N, Yajima K, Hikawa M, Shimura K, Ishii Y, Takada M, Uno Y, Utoh M, Iwasaki K, Yamazaki H.

Biopharm Drug Dispos. 2018 Feb;39(2):116-121. doi: 10.1002/bdd.2115. Epub 2017 Dec 21.

PMID:
29136681
23.

FKBP8 protects the heart from hemodynamic stress by preventing the accumulation of misfolded proteins and endoplasmic reticulum-associated apoptosis in mice.

Misaka T, Murakawa T, Nishida K, Omori Y, Taneike M, Omiya S, Molenaar C, Uno Y, Yamaguchi O, Takeda J, Shah AM, Otsu K.

J Mol Cell Cardiol. 2018 Jan;114:93-104. doi: 10.1016/j.yjmcc.2017.11.004. Epub 2017 Nov 10.

24.

Possible involvement of a cell adhesion molecule, Migfilin, in brain development and pathogenesis of autism spectrum disorders.

Ishizuka K, Tabata H, Ito H, Kushima I, Noda M, Yoshimi A, Usami M, Watanabe K, Morikawa M, Uno Y, Okada T, Mori D, Aleksic B, Ozaki N, Nagata KI.

J Neurosci Res. 2018 May;96(5):789-802. doi: 10.1002/jnr.24194. Epub 2017 Nov 8.

PMID:
29114925
25.

Molecular cloning and tissue distribution of a novel marmoset ABC transporter.

Uehara S, Uno Y, Inoue T, Sasaki E, Yamazaki H.

Biopharm Drug Dispos. 2018 Jan;39(1):59-63. doi: 10.1002/bdd.2111. Epub 2017 Dec 11.

PMID:
29059459
26.

Letter: low-FODMAP diet for exercise-induced gastrointestinal syndrome.

Uno Y.

Aliment Pharmacol Ther. 2017 Nov;46(10):1021-1022. doi: 10.1111/apt.14330. No abstract available.

PMID:
29052863
27.

Association with polymorphic marmoset cytochrome P450 2C19 of in vivo hepatic clearances of chirally separated R-omeprazole and S-warfarin using individual marmoset physiologically based pharmacokinetic models.

Kusama T, Toda A, Shimizu M, Uehara S, Inoue T, Uno Y, Utoh M, Sasaki E, Yamazaki H.

Xenobiotica. 2017 Nov 10:1-6. doi: 10.1080/00498254.2017.1393121. [Epub ahead of print]

PMID:
29034770
28.

Overexpression of microRNAs from the Gtl2-Rian locus contributes to postnatal death in mice.

Kumamoto S, Takahashi N, Nomura K, Fujiwara M, Kijioka M, Uno Y, Matsuda Y, Sotomaru Y, Kono T.

Hum Mol Genet. 2017 Oct 1;26(19):3653-3662. doi: 10.1093/hmg/ddx223.

29.

A novel rare variant R292H in RTN4R affects growth cone formation and possibly contributes to schizophrenia susceptibility.

Kimura H, Fujita Y, Kawabata T, Ishizuka K, Wang C, Iwayama Y, Okahisa Y, Kushima I, Morikawa M, Uno Y, Okada T, Ikeda M, Inada T, Branko A, Mori D, Yoshikawa T, Iwata N, Nakamura H, Yamashita T, Ozaki N.

Transl Psychiatry. 2017 Aug 22;7(8):e1214. doi: 10.1038/tp.2017.170.

30.

Social support helps protect against perinatal bonding failure and depression among mothers: a prospective cohort study.

Ohara M, Okada T, Aleksic B, Morikawa M, Kubota C, Nakamura Y, Shiino T, Yamauchi A, Uno Y, Murase S, Goto S, Kanai A, Masuda T, Nakatochi M, Ando M, Ozaki N.

Sci Rep. 2017 Aug 25;7(1):9546. doi: 10.1038/s41598-017-08768-3.

31.

Expression of cytochrome P450 regulators in cynomolgus macaque.

Uno Y, Yamazaki H.

Xenobiotica. 2018 Jul;48(7):695-703. doi: 10.1080/00498254.2017.1363928. Epub 2017 Sep 11.

PMID:
28812950
32.

Rare genetic variants in CX3CR1 and their contribution to the increased risk of schizophrenia and autism spectrum disorders.

Ishizuka K, Fujita Y, Kawabata T, Kimura H, Iwayama Y, Inada T, Okahisa Y, Egawa J, Usami M, Kushima I, Uno Y, Okada T, Ikeda M, Aleksic B, Mori D, Someya T, Yoshikawa T, Iwata N, Nakamura H, Yamashita T, Ozaki N.

Transl Psychiatry. 2017 Aug 1;7(8):e1184. doi: 10.1038/tp.2017.173.

33.

Progesterone hydroxylation by cytochromes P450 2C and 3A enzymes in marmoset liver microsomes.

Nakanishi K, Uehara S, Uno Y, Inoue T, Sasaki E, Yamazaki H.

Xenobiotica. 2018 Aug;48(8):757-763. doi: 10.1080/00498254.2017.1363444. Epub 2017 Aug 17.

PMID:
28762864
34.

Metabolism of 7-ethoxycoumarin, flavanone and steroids by cytochrome P450 2C9 variants.

Uno T, Nakano R, Kanamaru K, Takenaka S, Uno Y, Imaishi H.

Biopharm Drug Dispos. 2017 Nov;38(8):486-493. doi: 10.1002/bdd.2090. Epub 2017 Oct 13.

PMID:
28758225
35.

Development of genotyping method for functionally relevant variants of cytochromes P450 in cynomolgus macaques.

Uno Y, Osada N, Sakurai S, Shimozawa N, Iwata T, Ikeo K, Yamazaki H.

J Vet Pharmacol Ther. 2018 Feb;41(1):e30-e34. doi: 10.1111/jvp.12443. Epub 2017 Jul 28.

PMID:
28752932
36.

Enigma of Intestinal Gas in Irritable Bowel Syndrome.

Uno Y.

Am J Gastroenterol. 2017 Jul;112(7):1166-1167. doi: 10.1038/ajg.2017.75. No abstract available.

PMID:
28725060
37.

Localization and functional analysis of the insect-specific RabX4 in the brain of Bombyx mori.

Uno T, Furutani M, Sakamoto K, Uno Y, Kanamaru K, Mizoguchi A, Hiragaki S, Takeda M.

Arch Insect Biochem Physiol. 2017 Sep;96(1). doi: 10.1002/arch.21404. Epub 2017 Jul 14.

PMID:
28707374
38.

A rare case of pediatric primary cardiac tumor in a patient with Down syndrome.

Okada K, Masuoka A, Hotoda K, Uno Y, Suzuki T.

Asian Cardiovasc Thorac Ann. 2017 Nov;25(9):630-632. doi: 10.1177/0218492317721788. Epub 2017 Jul 13.

PMID:
28705019
39.

Marmoset pulmonary cytochrome P450 2F1 oxidizes biphenyl and 7-ethoxycoumarin and hepatic human P450 substrates.

Uehara S, Uno Y, Oshio T, Inoue T, Sasaki E, Yamazaki H.

Xenobiotica. 2018 Jul;48(7):656-662. doi: 10.1080/00498254.2017.1354138. Epub 2017 Jul 24.

PMID:
28689458
40.

Effects of aging and rifampicin pretreatment on the pharmacokinetics of human cytochrome P450 probes caffeine, warfarin, omeprazole, metoprolol and midazolam in common marmosets genotyped for cytochrome P450 2C19.

Toda A, Uehara S, Inoue T, Utoh M, Kusama T, Shimizu M, Uno Y, Mogi M, Sasaki E, Yamazaki H.

Xenobiotica. 2018 Jul;48(7):720-726. doi: 10.1080/00498254.2017.1353716. Epub 2017 Jul 25.

PMID:
28686070
41.

Hepatic expression of cytochrome P450 enzymes in non-human primate species.

Uehara S, Uno Y, Yamazaki H.

J Med Primatol. 2017 Dec;46(6):347-351. doi: 10.1111/jmp.12288. Epub 2017 Jun 29.

PMID:
28664555
42.

Efavirenz clearances in vitro and in vivo in six cynomolgus monkeys associated with polymorphic cytochrome P450 2C9 and simulated by individual physiologically based pharmacokinetic models.

Utoh M, Miura T, Kusama T, Uehara S, Shimizu M, Uno Y, Yamazaki H.

Biopharm Drug Dispos. 2017 Oct;38(7):439-442. doi: 10.1002/bdd.2084. Epub 2017 Jul 19.

PMID:
28608515
43.

Expression Profiling of Strawberry Allergen Fra a during Fruit Ripening Controlled by Exogenous Auxin.

Ishibashi M, Yoshikawa H, Uno Y.

Int J Mol Sci. 2017 Jun 2;18(6). pii: E1186. doi: 10.3390/ijms18061186.

44.

Relationship between maternal depression and bonding failure: A prospective cohort study of pregnant women.

Ohara M, Okada T, Kubota C, Nakamura Y, Shiino T, Aleksic B, Morikawa M, Yamauchi A, Uno Y, Murase S, Goto S, Kanai A, Masuda T, Ando M, Ozaki N.

Psychiatry Clin Neurosci. 2017 Oct;71(10):733-741. doi: 10.1111/pcn.12541. Epub 2017 Jul 7.

PMID:
28556440
45.

Corrigendum to "Genetic polymorphism of cynomolgus and rhesus macaque CYP2C9" [Drug Metab Pharmacokinet 30 (2015) 130-132].

Uno Y, Matsushita A, Murayama N, Yamazaki H.

Drug Metab Pharmacokinet. 2017 Jun;32(3):192. doi: 10.1016/j.dmpk.2017.04.001. Epub 2017 Apr 25. No abstract available.

PMID:
28522025
46.

Hybrid Palliation for Interrupted Aortic Arch With Small Aortic Valve.

Uno Y, Masuoka A, Hotoda K, Katogi T, Suzuki T.

World J Pediatr Congenit Heart Surg. 2017 May;8(3):332-336. doi: 10.1177/2150135117690125.

PMID:
28520542
47.

Large-Scale Phase Synchrony Reflects Clinical Status After Stroke: An EEG Study.

Kawano T, Hattori N, Uno Y, Kitajo K, Hatakenaka M, Yagura H, Fujimoto H, Yoshioka T, Nagasako M, Otomune H, Miyai I.

Neurorehabil Neural Repair. 2017 Jun;31(6):561-570. doi: 10.1177/1545968317697031. Epub 2017 Mar 22.

PMID:
28506148
48.

Regio- and Stereo-Selective Oxidation of a Cardiovascular Drug, Metoprolol, Mediated by Cytochrome P450 2D and 3A Enzymes in Marmoset Livers.

Uehara S, Ishii S, Uno Y, Inoue T, Sasaki E, Yamazaki H.

Drug Metab Dispos. 2017 Aug;45(8):896-899. doi: 10.1124/dmd.117.075630. Epub 2017 May 11.

PMID:
28495902
49.

Molecular Cloning and Characterization of Marmoset Aldehyde Oxidase.

Uehara S, Uno Y, Okamoto E, Inoue T, Sasaki E, Yamazaki H.

Drug Metab Dispos. 2017 Aug;45(8):883-886. doi: 10.1124/dmd.117.076042. Epub 2017 May 9.

PMID:
28487309
50.

Functional characterization and tissue expression of marmoset cytochrome P450 2E1.

Uehara S, Uno Y, Tomioka E, Inoue T, Sasaki E, Yamazaki H.

Biopharm Drug Dispos. 2017 Sep;38(6):394-397. doi: 10.1002/bdd.2080. Epub 2017 Jun 28.

PMID:
28474789

Supplemental Content

Support Center