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Items: 1 to 50 of 821

1.

Pseudouridines on Trypanosoma brucei spliceosomal small nuclear RNAs and their implication for RNA and protein interactions.

Rajan KS, Doniger T, Cohen-Chalamish S, Chen D, Semo O, Aryal S, Glick Saar E, Chikne V, Gerber D, Unger R, Tschudi C, Michaeli S.

Nucleic Acids Res. 2019 May 31. pii: gkz477. doi: 10.1093/nar/gkz477. [Epub ahead of print]

PMID:
31147702
2.

Integration of Multiple Epigenomic Marks Improves Prediction of Variant Impact in Saturation Mutagenesis Reporter Assay.

Shigaki D, Adato O, Adhikar AN, Dong S, Hawkins-Hooker A, Inoue F, Juven-Gershon T, Kenlay H, Martin B, Patra A, Penzar DP, Schubach M, Xiong C, Yan Z, Boyle AP, Kreimer A, Kulakovskiy IV, Reid J, Unger R, Yosef N, Shendure J, Ahituv N, Kircher M, Beer MA.

Hum Mutat. 2019 May 20. doi: 10.1002/humu.23797. [Epub ahead of print]

PMID:
31106481
3.

Identification of evolutionarily conserved downstream core promoter elements required for the transcriptional regulation of Fushi tarazu target genes.

Shir-Shapira H, Sloutskin A, Adato O, Ovadia-Shochat A, Ideses D, Zehavi Y, Kassavetis G, Kadonaga JT, Unger R, Juven-Gershon T.

PLoS One. 2019 Apr 18;14(4):e0215695. doi: 10.1371/journal.pone.0215695. eCollection 2019.

4.

Automated cell segmentation in FIJI® using the DRAQ5 nuclear dye.

Schwendy M, Unger RE, Bonn M, Parekh SH.

BMC Bioinformatics. 2019 Jan 18;20(1):39. doi: 10.1186/s12859-019-2602-2.

5.

Small nucleolar RNAs controlling rRNA processing in Trypanosoma brucei.

Chikne V, Shanmugha Rajan K, Shalev-Benami M, Decker K, Cohen-Chalamish S, Madmoni H, Biswas VK, Kumar Gupta S, Doniger T, Unger R, Tschudi C, Ullu E, Michaeli S.

Nucleic Acids Res. 2019 Mar 18;47(5):2609-2629. doi: 10.1093/nar/gky1287.

6.

Contact Order Is a Determinant for the Dependence of GFP Folding on the Chaperonin GroEL.

Bandyopadhyay B, Mondal T, Unger R, Horovitz A.

Biophys J. 2019 Jan 8;116(1):42-48. doi: 10.1016/j.bpj.2018.11.019. Epub 2018 Nov 22.

PMID:
30577980
7.

Primary Mucosal Epithelial Cell Cultivation: A Reliable and Accelerated Isolation.

Bauer HK, Flesch D, Walenta S, Unger RE, Schwab R, Nezi-Cahn S, Hasenburg A, Heller M, Brenner W.

Tissue Eng Part C Methods. 2019 Feb;25(2):82-92. doi: 10.1089/ten.TEC.2018.0327.

PMID:
30501564
8.

Iatrogenic hypertension: a bioinformatic analysis.

Botzer A, Finkelstein Y, Grossman E, Moult J, Unger R.

Pharmacogenomics J. 2018 Nov 5. doi: 10.1038/s41397-018-0062-0. [Epub ahead of print]

PMID:
30393374
9.

In vitro evaluation of a biomaterial-based anticancer drug delivery system as an alternative to conventional post-surgery bone cancer treatment.

Bischoff I, Tsaryk R, Chai F, Fürst R, Kirkpatrick CJ, Unger RE.

Mater Sci Eng C Mater Biol Appl. 2018 Dec 1;93:115-124. doi: 10.1016/j.msec.2018.07.057. Epub 2018 Jul 21.

PMID:
30274043
10.

Paraoxonase 1 (PON1) attenuates sperm hyperactivity and spontaneous acrosome reaction.

Efrat M, Stein A, Pinkas H, Breitbart H, Unger R, Birk R.

Andrology. 2019 Jan;7(1):24-30. doi: 10.1111/andr.12552. Epub 2018 Sep 17.

PMID:
30225889
11.

Corpora amylacea in prostatectomy tissue and associations with molecular, histological, and lifestyle factors.

DuPre NC, Flavin R, Sfanos KS, Unger RH, To S, Gazeeva E, Fiorentino M, De Marzo AM, Rider JR, Mucci LA; Transdisciplinary Prostate Cancer Partnership(ToPCaP).

Prostate. 2018 Nov;78(15):1172-1180. doi: 10.1002/pros.23692. Epub 2018 Jul 15.

PMID:
30009541
12.

Mechanical, degradation and drug-release behavior of nano-grained Fe-Ag composites for biomedical applications.

Sharipova A, Swain SK, Gotman I, Starosvetsky D, Psakhie SG, Unger R, Gutmanas EY.

J Mech Behav Biomed Mater. 2018 Oct;86:240-249. doi: 10.1016/j.jmbbm.2018.06.037. Epub 2018 Jun 26.

PMID:
29986299
13.

Endothelialization and Anticoagulation Potential of Surface-Modified PET Intended for Vascular Applications.

Giol ED, Van Vlierberghe S, Unger RE, Schaubroeck D, Ottevaere H, Thienpont H, Kirkpatrick CJ, Dubruel P.

Macromol Biosci. 2018 Jul;18(7):e1800125. doi: 10.1002/mabi.201800125. Epub 2018 Jun 13.

PMID:
29900675
14.

Sinus Floor Elevation Using the Lateral Approach and Window Repositioning and a Xenogeneic Bone Substitute as a Grafting Material: A Histologic, Histomorphometric, and Radiographic Analysis.

Tawil G, Barbeck M, Unger R, Tawil P, Witte F.

Int J Oral Maxillofac Implants. 2018 September/October;33(5):1089–1096. doi: 10.11607/jomi.6226. Epub 2018 Jun 12.

PMID:
29894551
15.

Dietary patterns are positively associated with semen quality.

Efrat M, Stein A, Pinkas H, Unger R, Birk R.

Fertil Steril. 2018 May;109(5):809-816. doi: 10.1016/j.fertnstert.2018.01.010.

PMID:
29778381
16.

Particles of vaterite, a metastable CaCO3 polymorph, exhibit high biocompatibility for human osteoblasts and endothelial cells and may serve as a biomaterial for rapid bone regeneration.

Schröder R, Besch L, Pohlit H, Panthöfer M, Roth W, Frey H, Tremel W, Unger RE.

J Tissue Eng Regen Med. 2018 Jul;12(7):1754-1768. doi: 10.1002/term.2703. Epub 2018 Jun 10.

PMID:
29770592
17.

Glucagon Receptor Antagonism Improves Glucose Metabolism and Cardiac Function by Promoting AMP-Mediated Protein Kinase in Diabetic Mice.

Sharma AX, Quittner-Strom EB, Lee Y, Johnson JA, Martin SA, Yu X, Li J, Lu J, Cai Z, Chen S, Wang MY, Zhang Y, Pearson MJ, Dorn AC, McDonald JG, Gordillo R, Yan H, Thai D, Wang ZV, Unger RH, Holland WL.

Cell Rep. 2018 Feb 13;22(7):1760-1773. doi: 10.1016/j.celrep.2018.01.065.

18.

Comparative genomic analysis of mollicutes with and without a chaperonin system.

Schwarz D, Adato O, Horovitz A, Unger R.

PLoS One. 2018 Feb 13;13(2):e0192619. doi: 10.1371/journal.pone.0192619. eCollection 2018.

19.

A system view and analysis of essential hypertension.

Botzer A, Grossman E, Moult J, Unger R.

J Hypertens. 2018 May;36(5):1094-1103. doi: 10.1097/HJH.0000000000001680.

PMID:
29369145
20.

The Responsiveness of Patient- Reported Outcome Tools in Shoulder Surgery Is Dependent on the Underlying Pathological Condition.

Unger RZ, Burnham JM, Gammon L, Malempati CS, Jacobs CA, Makhni EC.

Am J Sports Med. 2019 Jan;47(1):241-247. doi: 10.1177/0363546517749213. Epub 2018 Jan 11.

PMID:
29323925
21.

Sonographic large fetal head circumference and risk of cesarean delivery.

Lipschuetz M, Cohen SM, Israel A, Baron J, Porat S, Valsky DV, Yagel O, Amsalem H, Kabiri D, Gilboa Y, Sivan E, Unger R, Schiff E, Hershkovitz R, Yagel S.

Am J Obstet Gynecol. 2018 Mar;218(3):339.e1-339.e7. doi: 10.1016/j.ajog.2017.12.230. Epub 2018 Jan 2.

PMID:
29305249
22.

Effect of a glucagon receptor antibody (REMD-477) in type 1 diabetes: A randomized controlled trial.

Pettus J, Reeds D, Cavaiola TS, Boeder S, Levin M, Tobin G, Cava E, Thai D, Shi J, Yan H, Bautista E, McMillan J, Unger R, Henry RR, Klein S.

Diabetes Obes Metab. 2018 May;20(5):1302-1305. doi: 10.1111/dom.13202. Epub 2018 Jan 22.

23.

RNA editing by ADAR1 leads to context-dependent transcriptome-wide changes in RNA secondary structure.

Solomon O, Di Segni A, Cesarkas K, Porath HT, Marcu-Malina V, Mizrahi O, Stern-Ginossar N, Kol N, Farage-Barhom S, Glick-Saar E, Lerenthal Y, Levanon EY, Amariglio N, Unger R, Goldstein I, Eyal E, Rechavi G.

Nat Commun. 2017 Nov 13;8(1):1440. doi: 10.1038/s41467-017-01458-8.

24.

Local energetic frustration affects the dependence of green fluorescent protein folding on the chaperonin GroEL.

Bandyopadhyay B, Goldenzweig A, Unger T, Adato O, Fleishman SJ, Unger R, Horovitz A.

J Biol Chem. 2017 Dec 15;292(50):20583-20591. doi: 10.1074/jbc.M117.808576. Epub 2017 Oct 24.

25.

Machine learning for prediction of 30-day mortality after ST elevation myocardial infraction: An Acute Coronary Syndrome Israeli Survey data mining study.

Shouval R, Hadanny A, Shlomo N, Iakobishvili Z, Unger R, Zahger D, Alcalai R, Atar S, Gottlieb S, Matetzky S, Goldenberg I, Beigel R.

Int J Cardiol. 2017 Nov 1;246:7-13. doi: 10.1016/j.ijcard.2017.05.067.

PMID:
28867023
26.

An Integrative Scoring System for Survival Prediction Following Umbilical Cord Blood Transplantation in Acute Leukemia.

Shouval R, Ruggeri A, Labopin M, Mohty M, Sanz G, Michel G, Kuball J, Chevallier P, Al-Seraihy A, Milpied NJ, de Heredia CD, Arcese W, Blaise D, Rocha V, Fein J, Unger R, Baron F, Bader P, Gluckman E, Nagler A.

Clin Cancer Res. 2017 Nov 1;23(21):6478-6486. doi: 10.1158/1078-0432.CCR-17-0489. Epub 2017 Jul 28.

27.

Working toward precision medicine: Predicting phenotypes from exomes in the Critical Assessment of Genome Interpretation (CAGI) challenges.

Daneshjou R, Wang Y, Bromberg Y, Bovo S, Martelli PL, Babbi G, Lena PD, Casadio R, Edwards M, Gifford D, Jones DT, Sundaram L, Bhat RR, Li X, Pal LR, Kundu K, Yin Y, Moult J, Jiang Y, Pejaver V, Pagel KA, Li B, Mooney SD, Radivojac P, Shah S, Carraro M, Gasparini A, Leonardi E, Giollo M, Ferrari C, Tosatto SCE, Bachar E, Azaria JR, Ofran Y, Unger R, Niroula A, Vihinen M, Chang B, Wang MH, Franke A, Petersen BS, Pirooznia M, Zandi P, McCombie R, Potash JB, Altman RB, Klein TE, Hoskins RA, Repo S, Brenner SE, Morgan AA.

Hum Mutat. 2017 Sep;38(9):1182-1192. doi: 10.1002/humu.23280. Epub 2017 Jul 7.

28.

Amino Acid Transporter Slc38a5 Controls Glucagon Receptor Inhibition-Induced Pancreatic α Cell Hyperplasia in Mice.

Kim J, Okamoto H, Huang Z, Anguiano G, Chen S, Liu Q, Cavino K, Xin Y, Na E, Hamid R, Lee J, Zambrowicz B, Unger R, Murphy AJ, Xu Y, Yancopoulos GD, Li WH, Gromada J.

Cell Metab. 2017 Jun 6;25(6):1348-1361.e8. doi: 10.1016/j.cmet.2017.05.006.

29.

Dapagliflozin suppresses glucagon signaling in rodent models of diabetes.

Wang MY, Yu X, Lee Y, McCorkle SK, Chen S, Li J, Wang ZV, Davidson JA, Scherer PE, Holland WL, Unger RH, Roth MG.

Proc Natl Acad Sci U S A. 2017 Jun 20;114(25):6611-6616. doi: 10.1073/pnas.1705845114. Epub 2017 Jun 5.

30.

Bioresorbable β-TCP-FeAg nanocomposites for load bearing bone implants: High pressure processing, properties and cell compatibility.

Swain SK, Gotman I, Unger R, Gutmanas EY.

Mater Sci Eng C Mater Biol Appl. 2017 Sep 1;78:88-95. doi: 10.1016/j.msec.2017.04.051. Epub 2017 Apr 11.

PMID:
28576063
31.

Hypoglycemic Effect of Combined Ghrelin and Glucagon Receptor Blockade.

Mani BK, Uchida A, Lee Y, Osborne-Lawrence S, Charron MJ, Unger RH, Berglund ED, Zigman JM.

Diabetes. 2017 Jul;66(7):1847-1857. doi: 10.2337/db16-1303. Epub 2017 May 9.

32.

The Canonical Poly (A) Polymerase PAP1 Polyadenylates Non-Coding RNAs and Is Essential for snoRNA Biogenesis in Trypanosoma brucei.

Chikne V, Gupta SK, Doniger T, K SR, Cohen-Chalamish S, Waldman Ben-Asher H, Kolet L, Yahia NH, Unger R, Ullu E, Kolev NG, Tschudi C, Michaeli S.

J Mol Biol. 2017 Oct 27;429(21):3301-3318. doi: 10.1016/j.jmb.2017.04.015. Epub 2017 Apr 26.

PMID:
28456523
33.

Trade-off between Transcriptome Plasticity and Genome Evolution in Cephalopods.

Liscovitch-Brauer N, Alon S, Porath HT, Elstein B, Unger R, Ziv T, Admon A, Levanon EY, Rosenthal JJC, Eisenberg E.

Cell. 2017 Apr 6;169(2):191-202.e11. doi: 10.1016/j.cell.2017.03.025.

34.

Macrophage type modulates osteogenic differentiation of adipose tissue MSCs.

Zhang Y, Böse T, Unger RE, Jansen JA, Kirkpatrick CJ, van den Beucken JJJP.

Cell Tissue Res. 2017 Aug;369(2):273-286. doi: 10.1007/s00441-017-2598-8. Epub 2017 Mar 30.

35.

Insulin and Glucagon: Partners for Life.

Holst JJ, Holland W, Gromada J, Lee Y, Unger RH, Yan H, Sloop KW, Kieffer TJ, Damond N, Herrera PL.

Endocrinology. 2017 Apr 1;158(4):696-701. doi: 10.1210/en.2016-1748. Review.

36.

Glucagon antagonism in islet cell proliferation.

Dean ED, Unger RH, Holland WL.

Proc Natl Acad Sci U S A. 2017 Mar 21;114(12):3006-3008. doi: 10.1073/pnas.1700468114. Epub 2017 Mar 10. No abstract available.

37.

Gold nanoparticle interactions with endothelial cells cultured under physiological conditions.

Freese C, Anspach L, Deller RC, Richards SJ, Gibson MI, Kirkpatrick CJ, Unger RE.

Biomater Sci. 2017 Mar 28;5(4):707-717. doi: 10.1039/c6bm00853d.

PMID:
28184390
38.

Validation of the acute leukemia-EBMT score for prediction of mortality following allogeneic stem cell transplantation in a multi-center GITMO cohort.

Shouval R, Bonifazi F, Fein J, Boschini C, Oldani E, Labopin M, Raimondi R, Sacchi N, Dabash O, Unger R, Mohty M, Rambaldi A, Nagler A.

Am J Hematol. 2017 May;92(5):429-434. doi: 10.1002/ajh.24677. Epub 2017 Feb 21.

39.

Multinucleated giant cells in the implant bed of bone substitutes are foreign body giant cells-New insights into the material-mediated healing process.

Barbeck M, Booms P, Unger R, Hoffmann V, Sader R, Kirkpatrick CJ, Ghanaati S.

J Biomed Mater Res A. 2017 Apr;105(4):1105-1111. doi: 10.1002/jbm.a.36006. Epub 2017 Feb 2.

PMID:
28093892
40.

Perineural Invasion and Risk of Lethal Prostate Cancer.

Zareba P, Flavin R, Isikbay M, Rider JR, Gerke TA, Finn S, Pettersson A, Giunchi F, Unger RH, Tinianow AM, Andersson SO, Andrén O, Fall K, Fiorentino M, Mucci LA; Transdisciplinary Prostate Cancer Partnership (ToPCaP).

Cancer Epidemiol Biomarkers Prev. 2017 May;26(5):719-726. doi: 10.1158/1055-9965.EPI-16-0237. Epub 2017 Jan 6.

41.

The role of the intestinal microvasculature in inflammatory bowel disease: studies with a modified Caco-2 model including endothelial cells resembling the intestinal barrier in vitro.

Kasper JY, Hermanns MI, Cavelius C, Kraegeloh A, Jung T, Danzebrink R, Unger RE, Kirkpatrick CJ.

Int J Nanomedicine. 2016 Dec 7;11:6353-6364. eCollection 2016.

42.

Identification of neuronal and angiogenic growth factors in an in vitro blood-brain barrier model system: Relevance in barrier integrity and tight junction formation and complexity.

Freese C, Hanada S, Fallier-Becker P, Kirkpatrick CJ, Unger RE.

Microvasc Res. 2017 May;111:1-11. doi: 10.1016/j.mvr.2016.12.001. Epub 2016 Dec 15.

PMID:
27988246
43.

Sniffing out significant "Pee values": genome wide association study of asparagus anosmia.

Markt SC, Nuttall E, Turman C, Sinnott J, Rimm EB, Ecsedy E, Unger RH, Fall K, Finn S, Jensen MK, Rider JR, Kraft P, Mucci LA.

BMJ. 2016 Dec 13;355:i6071. doi: 10.1136/bmj.i6071.

44.

An in vitro and in vivo study of peptide-functionalized nanoparticles for brain targeting: The importance of selective blood-brain barrier uptake.

Bode GH, Coué G, Freese C, Pickl KE, Sanchez-Purrà M, Albaiges B, Borrós S, van Winden EC, Tziveleka LA, Sideratou Z, Engbersen JFJ, Singh S, Albrecht K, Groll J, Möller M, Pötgens AJG, Schmitz C, Fröhlich E, Grandfils C, Sinner FM, Kirkpatrick CJ, Steinbusch HWM, Frank HG, Unger RE, Martinez-Martinez P.

Nanomedicine. 2017 Apr;13(3):1289-1300. doi: 10.1016/j.nano.2016.11.009. Epub 2016 Nov 21.

PMID:
27884636
45.

Monocyte preseeding leads to an increased implant bed vascularization of biphasic calcium phosphate bone substitutes via vessel maturation.

Barbeck M, Unger RE, Booms P, Dohle E, Sader RA, Kirkpatrick CJ, Ghanaati S.

J Biomed Mater Res A. 2016 Dec;104(12):2928-2935. doi: 10.1002/jbm.a.35834. Epub 2016 Jul 21.

PMID:
27419378
46.

Impact of polymer-modified gold nanoparticles on brain endothelial cells: exclusion of endoplasmic reticulum stress as a potential risk factor.

Anspach L, Unger RE, Brochhausen C, Gibson MI, Klok HA, Kirkpatrick CJ, Freese C.

Nanotoxicology. 2016 Nov;10(9):1341-50. doi: 10.1080/17435390.2016.1214761. Epub 2016 Aug 5.

47.

Clinical Trials, Triumphs, and Tribulations of Glucagon Receptor Antagonists.

Pearson MJ, Unger RH, Holland WL.

Diabetes Care. 2016 Jul;39(7):1075-7. doi: 10.2337/dci15-0033. No abstract available.

48.

e23D: database and visualization of A-to-I RNA editing sites mapped to 3D protein structures.

Solomon O, Eyal E, Amariglio N, Unger R, Rechavi G.

Bioinformatics. 2016 Jul 15;32(14):2213-5. doi: 10.1093/bioinformatics/btw204. Epub 2016 Apr 19.

PMID:
27153640
49.

A pseudouridylation switch in rRNA is implicated in ribosome function during the life cycle of Trypanosoma brucei.

Chikne V, Doniger T, Rajan KS, Bartok O, Eliaz D, Cohen-Chalamish S, Tschudi C, Unger R, Hashem Y, Kadener S, Michaeli S.

Sci Rep. 2016 May 4;6:25296. doi: 10.1038/srep25296.

50.

Glucagon is the key factor in the development of diabetes.

Lee YH, Wang MY, Yu XX, Unger RH.

Diabetologia. 2016 Jul;59(7):1372-1375. doi: 10.1007/s00125-016-3965-9. Epub 2016 Apr 26. Review.

PMID:
27115412

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