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Items: 1 to 50 of 53

1.

A Phase I Study of ADCT-402 (Loncastuximab Tesirine), a Novel Pyrrolobenzodiazepine-Based Antibody-Drug Conjugate, in Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma.

Kahl BS, Hamadani M, Radford J, Carlo-Stella C, Caimi P, Reid E, Feingold JM, Ardeshna KM, Solh M, Heffner LT, Ungar D, He S, Boni J, Havenith K, O'Connor OA.

Clin Cancer Res. 2019 Nov 4. doi: 10.1158/1078-0432.CCR-19-0711. [Epub ahead of print]

PMID:
31685491
2.

The N-Glycosylation Processing Potential of the Mammalian Golgi Apparatus.

Fisher P, Thomas-Oates J, Wood AJ, Ungar D.

Front Cell Dev Biol. 2019 Aug 13;7:157. doi: 10.3389/fcell.2019.00157. eCollection 2019.

3.

Modeling Glycan Processing Reveals Golgi-Enzyme Homeostasis upon Trafficking Defects and Cellular Differentiation.

Fisher P, Spencer H, Thomas-Oates J, Wood AJ, Ungar D.

Cell Rep. 2019 Apr 23;27(4):1231-1243.e6. doi: 10.1016/j.celrep.2019.03.107.

4.

GORAB scaffolds COPI at the trans-Golgi for efficient enzyme recycling and correct protein glycosylation.

Witkos TM, Chan WL, Joensuu M, Rhiel M, Pallister E, Thomas-Oates J, Mould AP, Mironov AA, Biot C, Guerardel Y, Morelle W, Ungar D, Wieland FT, Jokitalo E, Tassabehji M, Kornak U, Lowe M.

Nat Commun. 2019 Jan 10;10(1):127. doi: 10.1038/s41467-018-08044-6.

5.

Glycans modify mesenchymal stem cell differentiation to impact on the function of resulting osteoblasts.

Wilson KM, Jagger AM, Walker M, Seinkmane E, Fox JM, Kröger R, Genever P, Ungar D.

J Cell Sci. 2018 Feb 14;131(4). pii: jcs209452. doi: 10.1242/jcs.209452.

6.

Cell-free Fluorescent Intra-Golgi Retrograde Vesicle Trafficking Assay.

Cottam NP, Ungar D.

Bio Protoc. 2017 Nov 20;7(22). pii: e2616. doi: 10.21769/BioProtoc.2616.

7.

Prevalence and impact of obesity in people with haemophilia: Review of literature and expert discussion around implementing weight management guidelines.

Kahan S, Cuker A, Kushner RF, Maahs J, Recht M, Wadden T, Willis T, Majumdar S, Ungar D, Cooper D.

Haemophilia. 2017 Nov;23(6):812-820. doi: 10.1111/hae.13291. Epub 2017 Jun 21. Review.

PMID:
28636076
8.

One Filter, One Sample, and the N- and O-Glyco(proteo)me: Toward a System to Study Disorders of Protein Glycosylation.

Skeene K, Walker M, Clarke G, Bergström E, Genever P, Ungar D, Thomas-Oates J.

Anal Chem. 2017 Jun 6;89(11):5840-5849. doi: 10.1021/acs.analchem.7b00143. Epub 2017 May 10.

9.

Epithelial-to-mesenchymal transition drives a pro-metastatic Golgi compaction process through scaffolding protein PAQR11.

Tan X, Banerjee P, Guo HF, Ireland S, Pankova D, Ahn YH, Nikolaidis IM, Liu X, Zhao Y, Xue Y, Burns AR, Roybal J, Gibbons DL, Zal T, Creighton CJ, Ungar D, Wang Y, Kurie JM.

J Clin Invest. 2017 Jan 3;127(1):117-131. doi: 10.1172/JCI88736. Epub 2016 Nov 21.

10.

The role of acroblast formation during Drosophila spermatogenesis.

Fári K, Takács S, Ungár D, Sinka R.

Biol Open. 2016 Aug 15;5(8):1102-10. doi: 10.1242/bio.018275.

11.

Molecular architecture of the complete COG tethering complex.

Ha JY, Chou HT, Ungar D, Yip CK, Walz T, Hughson FM.

Nat Struct Mol Biol. 2016 Aug;23(8):758-60. doi: 10.1038/nsmb.3263. Epub 2016 Jul 18.

12.

Glycan Profiling Shows Unvaried N-Glycomes in MSC Clones with Distinct Differentiation Potentials.

Wilson KM, Thomas-Oates JE, Genever PG, Ungar D.

Front Cell Dev Biol. 2016 May 31;4:52. doi: 10.3389/fcell.2016.00052. eCollection 2016.

13.

COG Complex Complexities: Detailed Characterization of a Complete Set of HEK293T Cells Lacking Individual COG Subunits.

Bailey Blackburn J, Pokrovskaya I, Fisher P, Ungar D, Lupashin VV.

Front Cell Dev Biol. 2016 Mar 30;4:23. doi: 10.3389/fcell.2016.00023. eCollection 2016.

14.

Bridging the Gap between Glycosylation and Vesicle Traffic.

Fisher P, Ungar D.

Front Cell Dev Biol. 2016 Mar 8;4:15. doi: 10.3389/fcell.2016.00015. eCollection 2016. Review.

15.

Filter-aided N-glycan separation (FANGS): a convenient sample preparation method for mass spectrometric N-glycan profiling.

Abdul Rahman S, Bergström E, Watson CJ, Wilson KM, Ashford DA, Thomas JR, Ungar D, Thomas-Oates JE.

J Proteome Res. 2014 Mar 7;13(3):1167-76. doi: 10.1021/pr401043r. Epub 2014 Feb 6.

16.

Dissecting functions of the conserved oligomeric Golgi tethering complex using a cell-free assay.

Cottam NP, Wilson KM, Ng BG, Körner C, Freeze HH, Ungar D.

Traffic. 2014 Jan;15(1):12-21. doi: 10.1111/tra.12128. Epub 2013 Oct 31.

17.

The Golgi puppet master: COG complex at center stage of membrane trafficking interactions.

Willett R, Ungar D, Lupashin V.

Histochem Cell Biol. 2013 Sep;140(3):271-83. doi: 10.1007/s00418-013-1117-6. Epub 2013 Jul 10. Review.

18.

COG complexes form spatial landmarks for distinct SNARE complexes.

Willett R, Kudlyk T, Pokrovskaya I, Schönherr R, Ungar D, Duden R, Lupashin V.

Nat Commun. 2013;4:1553. doi: 10.1038/ncomms2535.

19.

Molecular insights into vesicle tethering at the Golgi by the conserved oligomeric Golgi (COG) complex and the golgin TATA element modulatory factor (TMF).

Miller VJ, Sharma P, Kudlyk TA, Frost L, Rofe AP, Watson IJ, Duden R, Lowe M, Lupashin VV, Ungar D.

J Biol Chem. 2013 Feb 8;288(6):4229-40. doi: 10.1074/jbc.M112.426767. Epub 2012 Dec 13.

20.

Re'COG'nition at the Golgi.

Miller VJ, Ungar D.

Traffic. 2012 Jul;13(7):891-7. doi: 10.1111/j.1600-0854.2012.01338.x. Epub 2012 Feb 27. Review.

21.

Retrograde vesicle transport in the Golgi.

Cottam NP, Ungar D.

Protoplasma. 2012 Oct;249(4):943-55. Epub 2011 Dec 12. Review.

PMID:
22160157
22.

Fatal outcome due to deficiency of subunit 6 of the conserved oligomeric Golgi complex leading to a new type of congenital disorders of glycosylation.

Lübbehusen J, Thiel C, Rind N, Ungar D, Prinsen BH, de Koning TJ, van Hasselt PM, Körner C.

Hum Mol Genet. 2010 Sep 15;19(18):3623-33. doi: 10.1093/hmg/ddq278. Epub 2010 Jul 6.

PMID:
20605848
23.

Structural basis for a human glycosylation disorder caused by mutation of the COG4 gene.

Richardson BC, Smith RD, Ungar D, Nakamura A, Jeffrey PD, Lupashin VV, Hughson FM.

Proc Natl Acad Sci U S A. 2009 Aug 11;106(32):13329-34. doi: 10.1073/pnas.0901966106. Epub 2009 Jul 27.

24.

Golgi linked protein glycosylation and associated diseases.

Ungar D.

Semin Cell Dev Biol. 2009 Sep;20(7):762-9. doi: 10.1016/j.semcdb.2009.03.004. Review.

PMID:
19508859
25.

Epstein Barr virus induced lymphoma in a child with IPEX syndrome.

Lucas KG, Ungar D, Comito M, Groh B.

Pediatr Blood Cancer. 2008 May;50(5):1056-7.

PMID:
17828748
26.

Structural analysis of conserved oligomeric Golgi complex subunit 2.

Cavanaugh LF, Chen X, Richardson BC, Ungar D, Pelczer I, Rizo J, Hughson FM.

J Biol Chem. 2007 Aug 10;282(32):23418-26. Epub 2007 Jun 12.

27.

Molecular and clinical characterization of a Moroccan Cog7 deficient patient.

Ng BG, Kranz C, Hagebeuk EE, Duran M, Abeling NG, Wuyts B, Ungar D, Lupashin V, Hartdorff CM, Poll-The BT, Freeze HH.

Mol Genet Metab. 2007 Jun;91(2):201-4. Epub 2007 Mar 28.

28.

COG8 deficiency causes new congenital disorder of glycosylation type IIh.

Kranz C, Ng BG, Sun L, Sharma V, Eklund EA, Miura Y, Ungar D, Lupashin V, Winkel RD, Cipollo JF, Costello CE, Loh E, Hong W, Freeze HH.

Hum Mol Genet. 2007 Apr 1;16(7):731-41. Epub 2007 Mar 1.

PMID:
17331980
29.

A new inborn error of glycosylation due to a Cog8 deficiency reveals a critical role for the Cog1-Cog8 interaction in COG complex formation.

Foulquier F, Ungar D, Reynders E, Zeevaert R, Mills P, García-Silva MT, Briones P, Winchester B, Morelle W, Krieger M, Annaert W, Matthijs G.

Hum Mol Genet. 2007 Apr 1;16(7):717-30. Epub 2007 Jan 12.

PMID:
17220172
30.

Involving children with cancer in decision-making about research participation.

Joffe S, Fernandez CV, Pentz RD, Ungar DR, Mathew NA, Turner CW, Alessandri AJ, Woodman CL, Singer DA, Kodish E.

J Pediatr. 2006 Dec;149(6):862-868. Review. No abstract available.

PMID:
17137908
31.

Submyeloablative cord blood transplantation corrects clinical defects seen in IPEX syndrome.

Lucas KG, Ungar D, Comito M, Bayerl M, Groh B.

Bone Marrow Transplant. 2007 Jan;39(1):55-6. Epub 2006 Nov 20. No abstract available.

PMID:
17115064
32.

Children are not small adults: documentation of assent for research involving children.

Ungar D, Joffe S, Kodish E.

J Pediatr. 2006 Jul;149(1 Suppl):S31-3.

PMID:
16829240
33.

Synovial chondromatosis of the subtalar joint and tenosynovial chondromatosis of the posterior ankle.

Van P, Wilusz PM, Ungar DS, Pupp GR.

J Am Podiatr Med Assoc. 2006 Jan-Feb;96(1):59-62.

PMID:
16415284
34.

Retrograde transport on the COG railway.

Ungar D, Oka T, Krieger M, Hughson FM.

Trends Cell Biol. 2006 Feb;16(2):113-20. Epub 2006 Jan 10. Review.

PMID:
16406524
35.

Genetic analysis of the subunit organization and function of the conserved oligomeric golgi (COG) complex: studies of COG5- and COG7-deficient mammalian cells.

Oka T, Vasile E, Penman M, Novina CD, Dykxhoorn DM, Ungar D, Hughson FM, Krieger M.

J Biol Chem. 2005 Sep 23;280(38):32736-45. Epub 2005 Jul 28.

36.

Subunit architecture of the conserved oligomeric Golgi complex.

Ungar D, Oka T, Vasile E, Krieger M, Hughson FM.

J Biol Chem. 2005 Sep 23;280(38):32729-35. Epub 2005 Jul 14.

37.

[Limb salvage by excision of calcaneus in diabetic atherosclerotic gangrene].

Teleki B, Ungár D, Horánszky Z, Kalocsai L.

Magy Seb. 2004 Feb;57(1):43-6. Hungarian.

PMID:
15270522
38.

The COG and COPI complexes interact to control the abundance of GEARs, a subset of Golgi integral membrane proteins.

Oka T, Ungar D, Hughson FM, Krieger M.

Mol Biol Cell. 2004 May;15(5):2423-35. Epub 2004 Mar 5.

39.

SNARE protein structure and function.

Ungar D, Hughson FM.

Annu Rev Cell Dev Biol. 2003;19:493-517. Review.

PMID:
14570579
40.

Characterization of a mammalian Golgi-localized protein complex, COG, that is required for normal Golgi morphology and function.

Ungar D, Oka T, Brittle EE, Vasile E, Lupashin VV, Chatterton JE, Heuser JE, Krieger M, Waters MG.

J Cell Biol. 2002 Apr 29;157(3):405-15. Epub 2002 Apr 29.

41.

Analysis of a putative voltage-gated prokaryotic potassium channel.

Ungar D, Barth A, Haase W, Kaunzinger A, Lewitzki E, Ruiz T, Reiländer H, Michel H.

Eur J Biochem. 2001 Oct;268(20):5386-96.

42.

Chronic hepatitis C virus infections in leukemia survivors: prevalence, viral load, and severity of liver disease.

Paul IM, Sanders J, Ruggiero F, Andrews T, Ungar D, Eyster ME.

Blood. 1999 Jun 1;93(11):3672-7.

PMID:
10339473
43.

Patulous eustachian tube in a case of adolescent anorexia nervosa.

Karwautz A, Hafferl A, Ungar D, Sailer H.

Int J Eat Disord. 1999 Apr;25(3):353-5.

PMID:
10192003
44.

[Innovative respiratory muscle training for patients with Duchenne muscular dystrophy--a psychological evaluation].

Ungar D, Gössler R, Toifl K, Wanke T.

Wien Med Wochenschr. 1996;146(9-10):213-6. German.

PMID:
9012219
45.

PET hydroxyephedrine imaging of neuroblastoma.

Shulkin BL, Wieland DM, Baro ME, Ungar DR, Mitchell DS, Dole MG, Rawwas JB, Castle VP, Sisson JC, Hutchinson RJ.

J Nucl Med. 1996 Jan;37(1):16-21.

46.

Neoplasms in a pediatric population: 2-[F-18]-fluoro-2-deoxy-D-glucose PET studies.

Shulkin BL, Mitchell DS, Ungar DR, Prakash D, Dole MG, Castle VP, Hernandez RJ, Koeppe RA, Hutchinson RJ.

Radiology. 1995 Feb;194(2):495-500.

PMID:
7824731
47.

Nm23-H1 mutation in neuroblastoma.

Chang CL, Zhu XX, Thoraval DH, Ungar D, Rawwas J, Hora N, Strahler JR, Hanash SM, Radany E.

Nature. 1994 Aug 4;370(6488):335-6. No abstract available.

48.

Hsp27 expression in neuroblastoma: correlation with disease stage.

Ungar DR, Hailat N, Strahler JR, Kuick RD, Brodeur GM, Seeger RC, Reynolds CP, Hanash SM.

J Natl Cancer Inst. 1994 May 18;86(10):780-4.

PMID:
8169976
49.

Mapping of the gene for interferon-inducible dsRNA-dependent protein kinase to chromosome region 2p21-22: a site of rearrangements in myeloproliferative disorders.

Hanash SM, Beretta L, Barcroft CL, Sheldon S, Glover TW, Ungar D, Sonenberg N.

Genes Chromosomes Cancer. 1993 Sep;8(1):34-7.

PMID:
7691157
50.

Data base analysis of protein expression patterns during T-cell ontogeny and activation.

Hanash SM, Strahler JR, Chan Y, Kuick R, Teichroew D, Neel JV, Hailat N, Keim DR, Gratiot-Deans J, Ungar D, et al.

Proc Natl Acad Sci U S A. 1993 Apr 15;90(8):3314-8.

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