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Items: 40

1.

Ectoine-Containing Inhalation Solution versus Saline Inhalation Solution in the Treatment of Acute Bronchitis and Acute Respiratory Infections: A Prospective, Controlled, Observational Study.

Tran BH, Dao VA, Bilstein A, Unfried K, Shah-Hosseini K, Mösges R.

Biomed Res Int. 2019 Jan 31;2019:7945091. doi: 10.1155/2019/7945091. eCollection 2019.

2.

Induction of a senescent like phenotype and loss of gap junctional intercellular communication by carbon nanoparticle exposure of lung epithelial cells.

Spannbrucker T, Ale-Agha N, Goy C, Dyballa-Rukes N, Jakobs P, Jander K, Altschmied J, Unfried K, Haendeler J.

Exp Gerontol. 2019 Mar;117:106-112. doi: 10.1016/j.exger.2018.11.017. Epub 2018 Nov 23.

PMID:
30476532
3.

Syntheses of gold nanoparticles and their impact on the cell cycle in breast cancer cells subjected to megavoltage X-ray irradiation.

Hanžić N, Horvat A, Bibić J, Unfried K, Jurkin T, Dražić G, Marijanović I, Slade N, Gotić M.

Mater Sci Eng C Mater Biol Appl. 2018 Oct 1;91:486-495. doi: 10.1016/j.msec.2018.05.066. Epub 2018 May 22.

PMID:
30033280
4.

CDKN1B/p27 is localized in mitochondria and improves respiration-dependent processes in the cardiovascular system-New mode of action for caffeine.

Ale-Agha N, Goy C, Jakobs P, Spyridopoulos I, Gonnissen S, Dyballa-Rukes N, Aufenvenne K, von Ameln F, Zurek M, Spannbrucker T, Eckermann O, Jakob S, Gorressen S, Abrams M, Grandoch M, Fischer JW, Köhrer K, Deenen R, Unfried K, Altschmied J, Haendeler J.

PLoS Biol. 2018 Jun 21;16(6):e2004408. doi: 10.1371/journal.pbio.2004408. eCollection 2018 Jun.

5.

Non-Canonical Activation of the Epidermal Growth Factor Receptor by Carbon Nanoparticles.

Stöckmann D, Spannbrucker T, Ale-Agha N, Jakobs P, Goy C, Dyballa-Rukes N, Hornstein T, Kümper A, Kraegeloh A, Haendeler J, Unfried K.

Nanomaterials (Basel). 2018 Apr 23;8(4). pii: E267. doi: 10.3390/nano8040267.

6.

Reduction of neutrophilic lung inflammation by inhalation of the compatible solute ectoine: a randomized trial with elderly individuals.

Unfried K, Krämer U, Sydlik U, Autengruber A, Bilstein A, Stolz S, Marini A, Schikowski T, Keymel S, Krutmann J.

Int J Chron Obstruct Pulmon Dis. 2016 Oct 18;11:2573-2583. eCollection 2016.

7.

Epigallocatechin gallate (EGCG) inhibits adhesion and migration of neural progenitor cells in vitro.

Barenys M, Gassmann K, Baksmeier C, Heinz S, Reverte I, Schmuck M, Temme T, Bendt F, Zschauer TC, Rockel TD, Unfried K, Wätjen W, Sundaram SM, Heuer H, Colomina MT, Fritsche E.

Arch Toxicol. 2017 Feb;91(2):827-837. doi: 10.1007/s00204-016-1709-8. Epub 2016 Apr 26.

PMID:
27116294
8.

Staurosporine resistance in inflammatory neutrophils is associated with the inhibition of caspase- and proteasome-mediated Mcl-1 degradation.

Hornstein T, Lehmann S, Philipp D, Detmer S, Hoffmann M, Peter C, Wesselborg S, Unfried K, Windolf J, Flohé S, Paunel-Görgülü A.

J Leukoc Biol. 2016 Jan;99(1):163-74. doi: 10.1189/jlb.3A1114-537RR. Epub 2015 Aug 26.

9.

Preventing carbon nanoparticle-induced lung inflammation reduces antigen-specific sensitization and subsequent allergic reactions in a mouse model.

Kroker M, Sydlik U, Autengruber A, Cavelius C, Weighardt H, Kraegeloh A, Unfried K.

Part Fibre Toxicol. 2015 Jul 4;12:20. doi: 10.1186/s12989-015-0093-5.

10.

Signalling-dependent adverse health effects of carbon nanoparticles are prevented by the compatible solute mannosylglycerate (firoin) in vitro and in vivo.

Autengruber A, Sydlik U, Kroker M, Hornstein T, Ale-Agha N, Stöckmann D, Bilstein A, Albrecht C, Paunel-Görgülü A, Suschek CV, Krutmann J, Unfried K.

PLoS One. 2014 Nov 21;9(11):e111485. doi: 10.1371/journal.pone.0111485. eCollection 2014.

11.

The compatible solute ectoine reduces the exacerbating effect of environmental model particles on the immune response of the airways.

Unfried K, Kroker M, Autengruber A, Gotić M, Sydlik U.

J Allergy (Cairo). 2014;2014:708458. doi: 10.1155/2014/708458. Epub 2014 Apr 13.

12.

BDE-47 and 6-OH-BDE-47 modulate calcium homeostasis in primary fetal human neural progenitor cells via ryanodine receptor-independent mechanisms.

Gassmann K, Schreiber T, Dingemans MM, Krause G, Roderigo C, Giersiefer S, Schuwald J, Moors M, Unfried K, Bergman Å, Westerink RH, Rose CR, Fritsche E.

Arch Toxicol. 2014 Aug;88(8):1537-48. doi: 10.1007/s00204-014-1217-7. Epub 2014 Mar 6.

PMID:
24599297
13.

Carbon nanoparticles induce ceramide- and lipid raft-dependent signalling in lung epithelial cells: a target for a preventive strategy against environmentally-induced lung inflammation.

Peuschel H, Sydlik U, Grether-Beck S, Felsner I, Stöckmann D, Jakob S, Kroker M, Haendeler J, Gotić M, Bieschke C, Krutmann J, Unfried K.

Part Fibre Toxicol. 2012 Dec 10;9:48. doi: 10.1186/1743-8977-9-48.

14.

Recovery of neutrophil apoptosis by ectoine: a new strategy against lung inflammation.

Sydlik U, Peuschel H, Paunel-Görgülü A, Keymel S, Krämer U, Weissenberg A, Kroker M, Seghrouchni S, Heiss C, Windolf J, Bilstein A, Kelm M, Krutmann J, Unfried K.

Eur Respir J. 2013 Feb;41(2):433-42. doi: 10.1183/09031936.00132211. Epub 2012 Oct 25.

15.

Unhealthy diet and ultrafine carbon black particles induce senescence and disease associated phenotypic changes.

Büchner N, Ale-Agha N, Jakob S, Sydlik U, Kunze K, Unfried K, Altschmied J, Haendeler J.

Exp Gerontol. 2013 Jan;48(1):8-16. doi: 10.1016/j.exger.2012.03.017. Epub 2012 Apr 6.

PMID:
22507566
16.

Endothelial NADPH oxidase 2: when does it matter in atherosclerosis?

Haendeler J, Eckers A, Lukosz M, Unfried K, Altschmied J.

Cardiovasc Res. 2012 Apr 1;94(1):1-2. doi: 10.1093/cvr/cvs106. Epub 2012 Feb 23. No abstract available.

PMID:
22362815
17.

c-Src-mediated activation of Erk1/2 is a reaction of epithelial cells to carbon nanoparticle treatment and may be a target for a molecular preventive strategy.

Peuschel H, Sydlik U, Haendeler J, Büchner N, Stöckmann D, Kroker M, Wirth R, Brock W, Unfried K.

Biol Chem. 2010 Nov;391(11):1327-32. doi: 10.1515/BC.2010.131.

PMID:
20868224
18.

Reactive oxygen species as mediators of membrane-dependent signaling induced by ultrafine particles.

Weissenberg A, Sydlik U, Peuschel H, Schroeder P, Schneider M, Schins RP, Abel J, Unfried K.

Free Radic Biol Med. 2010 Aug 15;49(4):597-605. doi: 10.1016/j.freeradbiomed.2010.05.011. Epub 2010 Jun 4.

PMID:
20570722
19.

The compatible solute ectoine protects against nanoparticle-induced neutrophilic lung inflammation.

Sydlik U, Gallitz I, Albrecht C, Abel J, Krutmann J, Unfried K.

Am J Respir Crit Care Med. 2009 Jul 1;180(1):29-35. doi: 10.1164/rccm.200812-1911OC. Epub 2009 Mar 26.

PMID:
19324973
20.

The forkhead transcription factor FOXO4 sensitizes cancer cells to doxorubicin-mediated cytotoxicity.

Lüpertz R, Chovolou Y, Unfried K, Kampkötter A, Wätjen W, Kahl R.

Carcinogenesis. 2008 Nov;29(11):2045-52. doi: 10.1093/carcin/bgn184. Epub 2008 Aug 6.

PMID:
18687668
21.

Lack of association of delta-aminolevulinate dehydratase polymorphisms with blood lead levels and hemoglobin in Romanian women from a lead-contaminated region.

Rabstein S, Unfried K, Ranft U, Illig T, Kolz M, Mambetova C, Vlad M, Roman C, Weiss T, Becker D, Brüning T, Pesch B.

J Toxicol Environ Health A. 2008;71(11-12):716-24. doi: 10.1080/15287390801985190.

PMID:
18569569
22.

Carbon nanoparticle-induced lung epithelial cell proliferation is mediated by receptor-dependent Akt activation.

Unfried K, Sydlik U, Bierhals K, Weissenberg A, Abel J.

Am J Physiol Lung Cell Mol Physiol. 2008 Feb;294(2):L358-67. Epub 2007 Dec 14.

23.

Ultrafine carbon particles induce apoptosis and proliferation in rat lung epithelial cells via specific signaling pathways both using EGF-R.

Sydlik U, Bierhals K, Soufi M, Abel J, Schins RP, Unfried K.

Am J Physiol Lung Cell Mol Physiol. 2006 Oct;291(4):L725-33. Epub 2006 Jun 2.

24.

Variation of the N-acetyltransferase 2 gene in a Romanian and a Kyrgyz population.

Rabstein S, Unfried K, Ranft U, Illig T, Kolz M, Rihs HP, Mambetova C, Vlad M, Brüning T, Pesch B.

Cancer Epidemiol Biomarkers Prev. 2006 Jan;15(1):138-41.

25.
26.

Signal transduction pathways relevant for neoplastic effects of fibrous and non-fibrous particles.

Albrecht C, Borm PJ, Unfried K.

Mutat Res. 2004 Sep 3;553(1-2):23-35. Review.

PMID:
15288530
27.
28.

Environmental arsenic exposure from a coal-burning power plant as a potential risk factor for nonmelanoma skin carcinoma: results from a case-control study in the district of Prievidza, Slovakia.

Pesch B, Ranft U, Jakubis P, Nieuwenhuijsen MJ, Hergemöller A, Unfried K, Jakubis M, Miskovic P, Keegan T.

Am J Epidemiol. 2002 May 1;155(9):798-809.

PMID:
11978583
29.
30.

mRNA expression patterns in different stages of asbestos-induced carcinogenesis in rats.

Sandhu H, Dehnen W, Roller M, Abel J, Unfried K.

Carcinogenesis. 2000 May;21(5):1023-9.

PMID:
10783328
31.

Differential Display Analysis of Fiber-Induced Carcinogenesis in Rat: Clue for Involvement of Integrin-Mediated Signal Transduction.

Sandhu H, Olbrück H, Abel J, Unfried K.

Inhal Toxicol. 2000 Jan;12 Suppl 3:337-43. doi: 10.1080/08958378.2000.11463243.

PMID:
26368633
32.

Effects of Crocidolite Fibers on the Peritoneal Mesothelium of Rats.

Unfried K, Sandhu H, Schürkes C, Albrecht C, Abel J.

Inhal Toxicol. 2000 Jan;12 Suppl 3:149-55. doi: 10.1080/08958378.2000.11463208.

PMID:
26368611
33.

Upregulation of the RAS-GTPase activating protein (GAP)-binding protein (G3BP) in proliferating RPE cells.

Kociok N, Esser P, Unfried K, Parker F, Schraermeyer U, Grisanti S, Toqué B, Heimann K.

J Cell Biochem. 1999 Aug 1;74(2):194-201.

PMID:
10404389
34.
35.

The nonradioisotopic representation of differentially expressed mRNA by a combination of RNA fingerprinting and differential display.

Kociok N, Unfried K, Esser P, Krott R, Schraermeyer U, Heimann K.

Mol Biotechnol. 1998 Feb;9(1):25-33.

PMID:
9592766
36.

Expression and upregulation of microtubule-associated protein 1B in cultured retinal pigment epithelial cells.

Esser P, Grisanti S, Kociok N, Abts H, Hueber A, Unfried K, Heimann K, Weller M.

Invest Ophthalmol Vis Sci. 1997 Dec;38(13):2852-6.

PMID:
9418739
37.

Fiber-specific molecular features of tumors induced in rat peritoneum.

Unfried K, Roller M, Pott F, Friemann J, Dehnen W.

Environ Health Perspect. 1997 Sep;105 Suppl 5:1103-8.

38.

P53 mutations in tumours induced by intraperitoneal injection of crocidolite asbestos and benzo[a]pyrene in rats.

Unfried K, Kociok N, Roller M, Friemann J, Pott F, Dehnen W.

Exp Toxicol Pathol. 1997 Aug;49(3-4):181-7.

PMID:
9314051
39.
40.

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