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Quantitation of all Four Gardnerella vaginalis Clades Detects Abnormal Vaginal Microbiota Characteristic of Bacterial Vaginosis More Accurately than Putative G. vaginalis Sialidase A Gene Count.

Shipitsyna E, Krysanova A, Khayrullina G, Shalepo K, Savicheva A, Guschin A, Unemo M.

Mol Diagn Ther. 2019 Feb 5. doi: 10.1007/s40291-019-00382-5. [Epub ahead of print]


Prevalence, macrolide resistance and fluoroquinolone resistance in Mycoplasma genitalium in men who have sex with men (MSM) attending an STD Clinic in Dublin, Ireland in 2017-2018.

Mulligan V, Lynagh Y, Clarke S, Unemo M, Crowley B.

Sex Transm Dis. 2019 Jan 19. doi: 10.1097/OLQ.0000000000000940. [Epub ahead of print]


Pharmacokinetic considerations regarding the treatment of bacterial sexually transmitted infections with azithromycin: a review.

Kong FYS, Horner P, Unemo M, Hocking JS.

J Antimicrob Chemother. 2019 Jan 11. doi: 10.1093/jac/dky548. [Epub ahead of print]


Pharmacokinetic Data Are Predictive of in vivo Efficacy for Cefixime and Ceftriaxone against Susceptible and Resistant Neisseria gonorrhoeae Strains in the Gonorrhea Mouse Model.

Connolly KL, Eakin AE, Gomez C, Osborn BL, Unemo M, Jerse AE.

Antimicrob Agents Chemother. 2019 Jan 14. pii: AAC.01644-18. doi: 10.1128/AAC.01644-18. [Epub ahead of print]


Antibiotic resistance and NG-MAST sequence types of Neisseria gonorrhoeae isolates in Poland compared to the world.

Mlynarczyk-Bonikowska B, Malejczyk M, Majewski S, Unemo M.

Postepy Dermatol Alergol. 2018 Dec;35(6):346-551. doi: 10.5114/ada.2018.79780. Epub 2018 Nov 26. Review.


Antimicrobial resistance prediction and phylogenetic analysis of Neisseria gonorrhoeae isolates using the Oxford Nanopore MinION sequencer.

Golparian D, Donà V, Sánchez-Busó L, Foerster S, Harris S, Endimiani A, Low N, Unemo M.

Sci Rep. 2018 Dec 4;8(1):17596. doi: 10.1038/s41598-018-35750-4.


Stably high azithromycin resistance and decreasing ceftriaxone susceptibility in Neisseria gonorrhoeae in 25 European countries, 2016.

Day MJ, Spiteri G, Jacobsson S, Woodford N, Amato-Gauci AJ, Cole MJ, Unemo M; Euro-GASP network.

BMC Infect Dis. 2018 Dec 3;18(1):609. doi: 10.1186/s12879-018-3528-4.


Multidrug-resistant Neisseria gonorrhoeae isolate, belonging to the internationally spreading Japanese FC428 clone, with ceftriaxone resistance and intermediate resistance to azithromycin, Ireland, August 2018.

Golparian D, Rose L, Lynam A, Mohamed A, Bercot B, Ohnishi M, Crowley B, Unemo M.

Euro Surveill. 2018 Nov;23(47). doi: 10.2807/1560-7917.ES.2018.23.47.1800617.


Establishment of a Gonococcal Antimicrobial Surveillance Programme, in Accordance With World Health Organization Standards, in Côte d'Ivoire, Western Africa, 2014-2017.

Yéo A, Kouamé-Blavo B, Kouamé CE, Ouattara A, Yao AC, Gbedé BD, Bazan F, Faye-Ketté H, Dosso M, Wi T, Unemo M.

Sex Transm Dis. 2019 Mar;46(3):179-184. doi: 10.1097/OLQ.0000000000000943.


WHO laboratory validation of Xpert® CT/NG and Xpert® TV on the GeneXpert system verifies high performances.

Jacobsson S, Boiko I, Golparian D, Blondeel K, Kiarie J, Toskin I, Peeling RW, Unemo M.

APMIS. 2018 Dec;126(12):907-912. doi: 10.1111/apm.12902.


Lymphogranuloma venereum (LGV) in men who have sex with men (MSM): a re-emerging problem, Malta, 2018.

Donachie A, Spiteri G, Barbara C, Melillo T, Hadad R, Gauci Farrugia A, Unemo M, Padovese V.

Euro Surveill. 2018 Oct;23(43). doi: 10.2807/1560-7917.ES.2018.23.43.1800541.


Quantitative Proteomics of the 2016 WHO Neisseria gonorrhoeae Reference Strains Surveys Vaccine Candidates and Antimicrobial Resistance Determinants.

El-Rami FE, Zielke RA, Wi T, Sikora AE, Unemo M.

Mol Cell Proteomics. 2019 Jan;18(1):127-150. doi: 10.1074/mcp.RA118.001125. Epub 2018 Oct 23.


Antimicrobial Susceptibility of Neisseria gonorrhoeae Isolates in Yaoundé, Cameroon From 2009 to 2014.

Tayimetha CY, Unemo M.

Sex Transm Dis. 2018 Dec;45(12):e101-e103. doi: 10.1097/OLQ.0000000000000915.


Performance characteristics of newer MIC gradient strip tests compared with the Etest for antimicrobial susceptibility testing of Neisseria gonorrhoeae.

Jönsson A, Jacobsson S, Foerster S, Cole MJ, Unemo M.

APMIS. 2018 Oct;126(10):822-827. doi: 10.1111/apm.12887. Epub 2018 Sep 6.


Aptima Trichomonas vaginalis assay elucidates significant underdiagnosis of trichomoniasis among women in Brazil according to an observational study.

Bruni MP, Freitas da Silveira M, Stauffert D, Bicca GLO, Caetano Dos Santos C, da Rosa Farias NA, Golparian D, Unemo M.

Sex Transm Infect. 2018 Aug 28. pii: sextrans-2018-053635. doi: 10.1136/sextrans-2018-053635. [Epub ahead of print]


Gonorrhoea treatment failure caused by a Neisseria gonorrhoeae strain with combined ceftriaxone and high-level azithromycin resistance, England, February 2018.

Eyre DW, Sanderson ND, Lord E, Regisford-Reimmer N, Chau K, Barker L, Morgan M, Newnham R, Golparian D, Unemo M, Crook DW, Peto TE, Hughes G, Cole MJ, Fifer H, Edwards A, Andersson MI.

Euro Surveill. 2018 Jul;23(27). doi: 10.2807/1560-7917.ES.2018.23.27.1800323.


Advancing the public health applications of Chlamydia trachomatis serology.

Woodhall SC, Gorwitz RJ, Migchelsen SJ, Gottlieb SL, Horner PJ, Geisler WM, Winstanley C, Hufnagel K, Waterboer T, Martin DL, Huston WM, Gaydos CA, Deal C, Unemo M, Dunbar JK, Bernstein K.

Lancet Infect Dis. 2018 Dec;18(12):e399-e407. doi: 10.1016/S1473-3099(18)30159-2. Epub 2018 Jul 5. Review.


Mismatch Amplification Mutation Assay-Based Real-Time PCR for Rapid Detection of Neisseria gonorrhoeae and Antimicrobial Resistance Determinants in Clinical Specimens.

Donà V, Smid JH, Kasraian S, Egli-Gany D, Dost F, Imeri F, Unemo M, Low N, Endimiani A.

J Clin Microbiol. 2018 Aug 27;56(9). pii: e00365-18. doi: 10.1128/JCM.00365-18. Print 2018 Sep.


Should we be testing for urogenital Mycoplasma hominis, Ureaplasma parvum and Ureaplasma urealyticum in men and women? - a position statement from the European STI Guidelines Editorial Board.

Horner P, Donders G, Cusini M, Gomberg M, Jensen JS, Unemo M.

J Eur Acad Dermatol Venereol. 2018 Nov;32(11):1845-1851. doi: 10.1111/jdv.15146. Epub 2018 Jul 6. Review.


Antimicrobial resistance and molecular epidemiology using whole-genome sequencing of Neisseria gonorrhoeae in Ireland, 2014-2016: focus on extended-spectrum cephalosporins and azithromycin.

Ryan L, Golparian D, Fennelly N, Rose L, Walsh P, Lawlor B, Mac Aogáin M, Unemo M, Crowley B.

Eur J Clin Microbiol Infect Dis. 2018 Jun 7. doi: 10.1007/s10096-018-3296-5. [Epub ahead of print]


Multidrug-resistant Neisseria gonorrhoeae failing treatment with ceftriaxone and doxycycline in France, November 2017.

Poncin T, Fouere S, Braille A, Camelena F, Agsous M, Bebear C, Kumanski S, Lot F, Mercier-Delarue S, Ngangro NN, Salmona M, Schnepf N, Timsit J, Unemo M, Bercot B.

Euro Surveill. 2018 May;23(21). doi: 10.2807/1560-7917.ES.2018.23.21.1800264.


In vitro activity of the novel triazaacenaphthylene gepotidacin (GSK2140944) against MDR Neisseria gonorrhoeae.

Jacobsson S, Golparian D, Scangarella-Oman N, Unemo M.

J Antimicrob Chemother. 2018 Aug 1;73(8):2072-2077. doi: 10.1093/jac/dky162.


Public health surveillance of multidrug-resistant clones of Neisseria gonorrhoeae in Europe: a genomic survey.

Harris SR, Cole MJ, Spiteri G, Sánchez-Busó L, Golparian D, Jacobsson S, Goater R, Abudahab K, Yeats CA, Bercot B, Borrego MJ, Crowley B, Stefanelli P, Tripodo F, Abad R, Aanensen DM, Unemo M; Euro-GASP study group.

Lancet Infect Dis. 2018 Jul;18(7):758-768. doi: 10.1016/S1473-3099(18)30225-1. Epub 2018 May 15.


First nationwide antimicrobial susceptibility surveillance for Neisseria gonorrhoeae in Brazil, 2015-16.

Bazzo ML, Golfetto L, Gaspar PC, Pires AF, Ramos MC, Franchini M, Ferreira WA, Unemo M, Benzaken AS; Brazilian-GASP Network .

J Antimicrob Chemother. 2018 Jul 1;73(7):1854-1861. doi: 10.1093/jac/dky090.


In Vivo-Selected Compensatory Mutations Restore the Fitness Cost of Mosaic penA Alleles That Confer Ceftriaxone Resistance in Neisseria gonorrhoeae.

Vincent LR, Kerr SR, Tan Y, Tomberg J, Raterman EL, Dunning Hotopp JC, Unemo M, Nicholas RA, Jerse AE.

MBio. 2018 Apr 3;9(2). pii: e01905-17. doi: 10.1128/mBio.01905-17.


Dual antimicrobial therapy for gonorrhoea: what is the role of azithromycin?

Unemo M, Workowski K.

Lancet Infect Dis. 2018 May;18(5):486-488. doi: 10.1016/S1473-3099(18)30162-2. Epub 2018 Mar 6. No abstract available.


In vitro activity of zoliflodacin (ETX0914) against macrolide-resistant, fluoroquinolone-resistant and antimicrobial-susceptible Mycoplasma genitalium strains.

Damião Gouveia AC, Unemo M, Jensen JS.

J Antimicrob Chemother. 2018 May 1;73(5):1291-1294. doi: 10.1093/jac/dky022.


Neisseria cinerea with High Ceftriaxone MIC Is a Source of Ceftriaxone and Cefixime Resistance-Mediating penA Sequences in Neisseria gonorrhoeae.

Igawa G, Yamagishi Y, Lee KI, Dorin M, Shimuta K, Suematsu H, Nakayama SI, Mikamo H, Unemo M, Ohnishi M.

Antimicrob Agents Chemother. 2018 Feb 23;62(3). pii: e02069-17. doi: 10.1128/AAC.02069-17. Print 2018 Mar.


Mycoplasma genitalium: whole genome sequence analysis, recombination and population structure.

Fookes MC, Hadfield J, Harris S, Parmar S, Unemo M, Jensen JS, Thomson NR.

BMC Genomics. 2017 Dec 28;18(1):993. doi: 10.1186/s12864-017-4399-6.


Macrolide and fluoroquinolone resistance in Mycoplasma genitalium in two Swedish counties, 2011-2015.

Hadad R, Golparian D, Lagos AC, Ljungberg J, Nilsson P, Jensen JS, Fredlund H, Unemo M.

APMIS. 2018 Feb;126(2):123-127. doi: 10.1111/apm.12792. Epub 2017 Dec 13.


Systematic reviews of point-of-care tests for the diagnosis of urogenital Chlamydia trachomatis infections.

Kelly H, Coltart CEM, Pant Pai N, Klausner JD, Unemo M, Toskin I, Peeling RW.

Sex Transm Infect. 2017 Dec;93(S4):S22-S30. doi: 10.1136/sextrans-2016-053067. Review.


Performance and operational characteristics of point-of-care tests for the diagnosis of urogenital gonococcal infections.

Guy RJ, Causer LM, Klausner JD, Unemo M, Toskin I, Azzini AM, Peeling RW.

Sex Transm Infect. 2017 Dec;93(S4):S16-S21. doi: 10.1136/sextrans-2017-053192. Review.


In vitro activity and time-kill curve analysis of sitafloxacin against a global panel of antimicrobial-resistant and multidrug-resistant Neisseria gonorrhoeae isolates.

Jönsson A, Foerster S, Golparian D, Hamasuna R, Jacobsson S, Lindberg M, Jensen JS, Ohnishi M, Unemo M.

APMIS. 2018 Jan;126(1):29-37. doi: 10.1111/apm.12777. Epub 2017 Nov 20.


Fitness cost and benefit of antimicrobial resistance in Neisseria gonorrhoeae: Multidisciplinary approaches are needed.

Unemo M, Althaus CL.

PLoS Med. 2017 Oct 31;14(10):e1002423. doi: 10.1371/journal.pmed.1002423. eCollection 2017 Oct.


Multidrug-resistant Neisseria gonorrhoeae infection with ceftriaxone resistance and intermediate resistance to azithromycin, Denmark, 2017.

Terkelsen D, Tolstrup J, Johnsen CH, Lund O, Larsen HK, Worning P, Unemo M, Westh H.

Euro Surveill. 2017 Oct;22(42). doi: 10.2807/1560-7917.ES.2017.22.42.17-00659.


Role of Molecular Biology in Diagnosis and Characterization of Vulvo-Vaginitis in Clinical Practice.

Donders GGG, Ravel J, Vitali B, Netea MG, Salumets A, Unemo M.

Gynecol Obstet Invest. 2017;82(6):607-616. doi: 10.1159/000478982. Epub 2017 Oct 10.


Clinical and analytical evaluation of the new Aptima Mycoplasma genitalium assay, with data on M. genitalium prevalence and antimicrobial resistance in M. genitalium in Denmark, Norway and Sweden in 2016.

Unemo M, Salado-Rasmussen K, Hansen M, Olsen AO, Falk M, Golparian D, Aasterød M, Ringlander J, Nilsson CS, Sundqvist M, Schønning K, Moi H, Westh H, Jensen JS.

Clin Microbiol Infect. 2018 May;24(5):533-539. doi: 10.1016/j.cmi.2017.09.006. Epub 2017 Sep 18.


Genomic Characterization of Urethritis-Associated Neisseria meningitidis Shows that a Wide Range of N. meningitidis Strains Can Cause Urethritis.

Ma KC, Unemo M, Jeverica S, Kirkcaldy RD, Takahashi H, Ohnishi M, Grad YH.

J Clin Microbiol. 2017 Dec;55(12):3374-3383. doi: 10.1128/JCM.01018-17. Epub 2017 Sep 13.


In Vitro Activity of the Novel Pleuromutilin Lefamulin (BC-3781) and Effect of Efflux Pump Inactivation on Multidrug-Resistant and Extensively Drug-Resistant Neisseria gonorrhoeae.

Jacobsson S, Paukner S, Golparian D, Jensen JS, Unemo M.

Antimicrob Agents Chemother. 2017 Oct 24;61(11). pii: e01497-17. doi: 10.1128/AAC.01497-17. Print 2017 Nov.


Overall Low Extended-Spectrum Cephalosporin Resistance but high Azithromycin Resistance in Neisseria gonorrhoeae in 24 European Countries, 2015.

Cole MJ, Spiteri G, Jacobsson S, Woodford N, Tripodo F, Amato-Gauci AJ, Unemo M; Euro-GASP network.

BMC Infect Dis. 2017 Sep 11;17(1):617. doi: 10.1186/s12879-017-2707-z.


Infection: Proof of principle for effectiveness of a gonorrhoea vaccine.

Unemo M, Sikora AE.

Nat Rev Urol. 2017 Nov;14(11):643-644. doi: 10.1038/nrurol.2017.139. Epub 2017 Aug 31. No abstract available.


Multidrug-resistant gonorrhea: A research and development roadmap to discover new medicines.

Alirol E, Wi TE, Bala M, Bazzo ML, Chen XS, Deal C, Dillon JR, Kularatne R, Heim J, Hooft van Huijsduijnen R, Hook EW, Lahra MM, Lewis DA, Ndowa F, Shafer WM, Tayler L, Workowski K, Unemo M, Balasegaram M.

PLoS Med. 2017 Jul 26;14(7):e1002366. doi: 10.1371/journal.pmed.1002366. eCollection 2017 Jul.


Recent advances in the development and use of molecular tests to predict antimicrobial resistance in Neisseria gonorrhoeae.

Donà V, Low N, Golparian D, Unemo M.

Expert Rev Mol Diagn. 2017 Sep;17(9):845-859. doi: 10.1080/14737159.2017.1360137. Epub 2017 Aug 3. Review.


Ten years transmission of the new variant of Chlamydia trachomatis in Sweden: prevalence of infections and associated complications.

Dahlberg J, Hadad R, Elfving K, Larsson I, Isaksson J, Magnuson A, Fredlund H, Unemo M, Herrmann B.

Sex Transm Infect. 2018 Mar;94(2):100-104. doi: 10.1136/sextrans-2016-052992. Epub 2017 Jul 19.


Sexually transmitted infections: challenges ahead.

Unemo M, Bradshaw CS, Hocking JS, de Vries HJC, Francis SC, Mabey D, Marrazzo JM, Sonder GJB, Schwebke JR, Hoornenborg E, Peeling RW, Philip SS, Low N, Fairley CK.

Lancet Infect Dis. 2017 Aug;17(8):e235-e279. doi: 10.1016/S1473-3099(17)30310-9. Epub 2017 Jul 9. Review.


Antimicrobial resistance in Neisseria gonorrhoeae: Global surveillance and a call for international collaborative action.

Wi T, Lahra MM, Ndowa F, Bala M, Dillon JR, Ramon-Pardo P, Eremin SR, Bolan G, Unemo M.

PLoS Med. 2017 Jul 7;14(7):e1002344. doi: 10.1371/journal.pmed.1002344. eCollection 2017 Jul.


Rapid accurate point-of-care tests combining diagnostics and antimicrobial resistance prediction for Neisseria gonorrhoeae and Mycoplasma genitalium.

Sadiq ST, Mazzaferri F, Unemo M.

Sex Transm Infect. 2017 Dec;93(S4):S65-S68. doi: 10.1136/sextrans-2016-053072. Epub 2017 Jul 6.


Trichomonas vaginalis is Rare Among Women in Iceland.

Hilmarsdottir I, Sigmundsdottir E, Eiriksdottir A, Golparian D, Unemo M.

Acta Derm Venereol. 2017 Nov 15;97(10):1258-1260. doi: 10.2340/00015555-2747. No abstract available.


Trichomonas vaginalis is very rare among women with vaginal discharge in Podlaskie province, Poland.

Serwin AB, Bulhak-Koziol V, Sokolowska M, Golparian D, Unemo M.

APMIS. 2017 Sep;125(9):840-843. doi: 10.1111/apm.12713. Epub 2017 Jun 14.


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